EKS-ORL-00398

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORL-00398

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	302.3	3.5E-90	30	281	252

Status

Unreviewed

Ensembl Protein

ENSORLP00000001389

UniProt Accession

H2L6E2;

Protein Name

Protein Synonyms/Alias

Gene Name

TAOK3 (1 of 2)

Gene Synonyms/Alias

TAOK3 (1 of 2);

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSORLG00000001125	ENSORLP00000001389	ENSORLT00000001390

Organism

Oryzias latipes

Functional Description

Protein Length

928

Protein Sequence
(FASTA)

MPSSTRKAVP KDPELGDLFF KDDPEDVFCD LHEIGHGSFG AVYFARNSYS NEVVAIKKMS 60

YNGKQTTEKW QDIIKEVKFL GQLRHPNTIE YKGCYLKDNT AWLVMEYCLG SASDLLEVHK 120

KPLQEMEIAA ITHGALLGLA YLHSHNMIHR DVKAGNILLT ELGLVKLADF GSASIASPAN 180

SFVGTPYWMA PEVILAMDEG QYEGKVDIWS LGITCIELAE RKPPLFNMNA MSALYHIAQN 240

DSPTLQSNEW SDIFRSFVDY CLLKIPQDRP SSGELLRHDF VRRDRSPRIL LDLIQRTKDA 300

VRELDNLQYR KMKKILYQEK HNGLMGESQE EEEEKRISKE TEEEPLTSNE AASCKMNSLG 360

SNHSIPSTSV STGSQSSSVN SMQEVLEDNC SDMAMMHPQD YSGNLDASSH AKKVKHPKKR 420

KTLTDVLFWT QDHQYNWDDG IHRDQRPEPR SASSERSSQA QNYKNQGRFA TIKSASLVTK 480

QIHEHEQESE LREQMSGYKR MRRQHQKQLI ALENKLKAEM DEHRLKLQKE VETQANNAYI 540

ELEKLAKRHA ALTDKEMKTA LTDEKKFQQQ IVAQQKKELT TFLDNQKKQY KLCKEKIKET 600

HTREHPQASA EPLIQTEDLW PPQSPERTWG GPLLSQQRVF YDRNCRAFKR KVMIRRHDVE 660

QEQIREELNK KKTQKEMEHA MLIRHDESTQ ELEQRQLKNL QKLRMDLIRL QHQTELENQI 720

EYNNRREREL HRKHVLELRQ QPKNLKVLEL QIKKQFQDTC KVQTKQYKAL RHHQMEVTPK 780

AEHKTVLKAL KDEQTRKLAI LAEQYEQSIN EMMASQALRL DEAQEAECQA LRLQLQQEME 840

LLNAYQSKIK MQTEAQHERE QQKLEQKVSL RRAHLEQKIE EELGSLQKER TDRIKHLLER 900

QEREIDSFDM ESMRLGFSNL GILDFPKD 928

Nucleotide Sequence
(FASTA)

ATGCCGTCGT CCACAAGGAA GGCGGTGCCG AAGGACCCCG AGCTGGGTGA CCTCTTCTTC 60

AAAGATGACC CAGAGGACGT GTTCTGCGAC CTGCACGAGA TCGGACATGG CAGCTTTGGG 120

GCCGTCTACT TTGCACGAAA CTCGTACTCC AACGAGGTGG TGGCCATCAA GAAGATGTCC 180

TACAACGGCA AGCAGACGAC GGAGAAGTGG CAGGACATCA TCAAGGAGGT CAAGTTTTTG 240

GGGCAGCTGC GACACCCCAA CACCATCGAG TACAAAGGCT GCTACCTGAA GGACAACACC 300

GCCTGGCTGG TGATGGAGTA CTGCCTGGGC TCTGCATCTG ATCTACTAGA AGTTCACAAG 360

AAACCACTCC AAGAAATGGA AATTGCTGCC ATTACCCACG GTGCCTTGTT AGGACTGGCC 420

TACTTACATT CCCATAACAT GATTCACAGA GATGTGAAAG CTGGCAACAT CCTGCTGACT 480

GAGCTGGGCC TGGTCAAGCT GGCTGACTTT GGCTCCGCCT CCATTGCCTC ACCTGCCAAC 540

TCCTTTGTCG GAACGCCGTA CTGGATGGCC CCTGAAGTGA TTTTAGCCAT GGACGAGGGT 600

CAGTACGAGG GGAAAGTGGA CATCTGGTCG CTGGGGATCA CCTGTATTGA ACTGGCGGAG 660

CGTAAGCCGC CGCTGTTCAA CATGAATGCA ATGAGTGCCT TATACCACAT CGCACAGAAC 720

GACTCCCCCA CGCTGCAGTC CAACGAGTGG TCCGACATCT TCCGGAGCTT CGTTGACTAT 780

TGCCTACTAA AAATTCCTCA GGACAGACCC TCGTCAGGGG AGCTGCTGCG ACATGACTTT 840

GTGCGTCGGG ATCGCTCGCC GCGCATCCTC CTGGACCTCA TCCAGAGGAC CAAGGATGCG 900

GTGCGCGAAC TGGACAACCT GCAGTACCGC AAGATGAAGA AGATTCTGTA CCAGGAGAAG 960

CACAACGGGC TGATGGGAGA AAGCCAGGAG GAGGAAGAGG AGAAAAGAAT CAGTAAGGAA 1020

ACAGAAGAAG AACCTTTGAC TTCAAATGAG GCGGCTAGCT GTAAGATGAA CAGCCTGGGC 1080

AGCAACCACT CCATCCCCAG CACGTCGGTC AGCACCGGCA GCCAGAGCAG CAGCGTCAAC 1140

AGCATGCAGG AGGTGCTGGA GGACAACTGC TCCGACATGG CCATGATGCA CCCGCAGGAC 1200

TACAGTGGCA ACCTGGACGC GTCCTCGCAC GCCAAGAAGG TGAAGCACCC TAAAAAAAGA 1260

AAAACTCTGA CGGATGTTTT GTTTTGGACT CAGGACCATC AGTACAACTG GGATGACGGG 1320

ATCCACAGAG ACCAGCGGCC CGAGCCCAGG TCGGCCTCCT CCGAACGCAG CAGCCAGGCC 1380

CAAAACTACA AAAACCAGGG CCGTTTCGCC ACCATAAAGT CAGCCTCTCT GGTCACCAAA 1440

CAAATCCACG AGCATGAGCA GGAAAGCGAG CTGCGGGAGC AGATGTCGGG CTACAAGCGC 1500

ATGCGGCGGC AGCACCAGAA GCAGCTCATC GCCCTGGAGA ACAAGCTGAA GGCTGAGATG 1560

GACGAGCACC GGCTGAAGCT GCAAAAGGAG GTGGAGACGC AGGCCAACAA CGCCTACATC 1620

GAGCTGGAGA AGCTGGCCAA ACGCCACGCG GCGCTGACTG ACAAAGAGAT GAAGACGGCG 1680

CTCACGGATG AGAAGAAGTT CCAGCAGCAG ATCGTGGCGC AGCAGAAGAA GGAGCTGACC 1740

ACCTTCCTGG ACAACCAGAA GAAGCAATAC AAACTCTGCA AGGAGAAGAT TAAGGAGACA 1800

CACACACGTG AACACCCCCA AGCCTCCGCT GAGCCGTTAA TCCAAACGGA GGATTTGTGG 1860

CCTCCACAAT CTCCAGAAAG AACGTGGGGA GGCCCCCTGC TGAGCCAGCA GAGGGTTTTC 1920

TACGACCGCA ACTGCCGCGC CTTCAAGCGC AAAGTCATGA TCAGGAGGCA CGACGTGGAG 1980

CAGGAGCAGA TCCGAGAGGA ACTGAACAAG AAGAAGACCC AGAAAGAGAT GGAGCACGCC 2040

ATGCTGATCC GCCACGACGA GTCCACGCAG GAGCTGGAGC AGCGGCAGCT GAAGAACCTG 2100

CAGAAGCTGC GCATGGACCT CATCCGCCTG CAGCACCAGA CGGAGCTGGA GAACCAGATC 2160

GAGTACAACA ACCGGCGAGA GCGCGAGCTC CACCGCAAAC ACGTGCTGGA GCTGCGGCAG 2220

CAGCCCAAGA ACCTGAAGGT GTTGGAGCTG CAGATAAAGA AGCAGTTCCA GGACACGTGT 2280

AAGGTGCAGA CCAAACAGTA CAAGGCTCTG CGCCACCACC AGATGGAAGT CACCCCCAAG 2340

GCGGAGCACA AGACGGTGCT GAAGGCCCTG AAGGACGAGC AGACGCGCAA GCTGGCCATC 2400

CTGGCCGAGC AGTACGAGCA GAGCATCAAC GAGATGATGG CCTCGCAGGC TCTGCGTCTG 2460

GACGAAGCCC AGGAAGCCGA GTGTCAGGCC CTGCGGCTGC AGCTGCAGCA GGAGATGGAG 2520

CTGCTCAACG CCTACCAGAG CAAGATCAAG ATGCAGACCG AGGCGCAGCA CGAGCGCGAG 2580

CAGCAGAAGC TGGAGCAGAA GGTGTCGCTG CGCCGCGCTC ACCTGGAACA AAAGATCGAA 2640

GAGGAGCTGG GTTCCCTTCA GAAGGAGCGG ACCGACCGCA TCAAACACCT GCTGGAGCGC 2700

CAGGAGCGCG AGATCGACAG CTTCGACATG GAGAGCATGC GGCTGGGCTT CAGCAACCTG 2760

GGCATCCTGG ACTTTCCCAA GGAC 2784

Domain Profile

S: 3     lleeigkGalgkvylarekktgelvaikkinlekq...ekleelqkeisvlkklkhpniv  59

          l+eig+G++g+vy ar+  ++e+vaikk++++ +   ek+++++ke+++l +l+hpn +

Q: 30    DLHEIGHGSFGAVYFARNSYSNEVVAIKKMSYNGKqttEKWQDIIKEVKFLGQLRHPNTI  89

         5789****************************988889**********************

S: 60    eylesflkeeelwlvmeylagGslsdlvkeelkselkEeqiayilrevlkaLeylHskkv  119

         ey +++lk+++ wlvmey+  Gs+sdl++ ++k++l+E +ia+i++++l +L+ylHs+++

Q: 90    EYKGCYLKDNTAWLVMEYCL-GSASDLLE-VHKKPLQEMEIAAITHGALLGLAYLHSHNM  147

         *******************7.********.******************************

S: 120   iHrdikakniLlteegeVkLsdfgvaaqlektrkkrktvvgtpywmAPEviaqe.ekgYd  178

         iHrd+ka+niLlte g VkL+dfg+a+  +      +++vgtpywmAPEvi ++ e +Y+

Q: 148   IHRDVKAGNILLTELGLVKLADFGSASIASP----ANSFVGTPYWMAPEVILAMdEGQYE  203

         ************************9988887....69**************9887999**

S: 179   ekaDiwslGItaielaegepPfkdleplkallkilkneppklkskkkfskefkefvekcl  238

          k+DiwslGIt+ielae++pP++++++++al++i++n++p+l+s+ ++s+ f++fv+ cl

Q: 204   GKVDIWSLGITCIELAERKPPLFNMNAMSALYHIAQNDSPTLQSN-EWSDIFRSFVDYCL  262

         ******************************************888.**************

S: 239   qknpekRpsasellkhkFl  257

          k p++Rps+ ell+h F+

Q: 263   LKIPQDRPSSGELLRHDFV  281

         *****************97

Domain Sequence
(FASTA)

DLHEIGHGSF GAVYFARNSY SNEVVAIKKM SYNGKQTTEK WQDIIKEVKF LGQLRHPNTI 60

EYKGCYLKDN TAWLVMEYCL GSASDLLEVH KKPLQEMEIA AITHGALLGL AYLHSHNMIH 120

RDVKAGNILL TELGLVKLAD FGSASIASPA NSFVGTPYWM APEVILAMDE GQYEGKVDIW 180

SLGITCIELA ERKPPLFNMN AMSALYHIAQ NDSPTLQSNE WSDIFRSFVD YCLLKIPQDR 240

PSSGELLRHD FV 252

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013