EPS-ORL-00086

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-ORL-00086

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/PTEN	257.7	9.2E-77	5	175	171

Status

Unreviewed

Ensembl Protein

ENSORLP00000001868

UniProt Accession

H2L7Q1;

Protein Name

Protein Synonyms/Alias

Gene Name

TENC1 (1 of 2)

Gene Synonyms/Alias

TENC1 (1 of 2);

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSORLG00000001505	ENSORLP00000001868	ENSORLT00000001869

Organism

Oryzias latipes

Functional Description

Protein Length

1583

Protein Sequence
(FASTA)

RVMERVMERN YDFDLTYITE RIISVFFPPK LEEQRYRINL KEVAAMLKSK HQDKFLLLNL 60

SERRHDITRL NPKVQDFGWP DLHAPPLDKI CAICKAMETW LTSDPQHVVV LHCKGNKGKT 120

GVIIAAYMHY SKISAGADQA LSTLAMRKFC EDKVSSSLQP SQNRYIYYFG GLLSGAIKMN 180

SSPLFLHQVL IPSLPNFQGE GGYYPFLKIY QCMQLVYTSG IYDLQGTGGR RLCVTIEPAL 240

LLKGDIMVKC YHRQAQSADR DTVFRLQFHT CTVHGSQLWF GKGELDEAFT DERFPSDATV 300

EFIFSSGPER IKGREYHKND PAVTVDYNTA DPVVRWDSYE NFNQRYQDSL EDIAHTRGPV 360

DGSLYAQIKK RRAAGSGSLN STNGSSPGGP LGDDRPDHFI GRGSDSALSA HSLHLNQAST 420

HPDHDEALLR PPPPPTRQER EELERLLGGI EGSRDGERET AILDDGDTLE RTGTLGLSRS 480

CSCREGYRSQ RCAEPGCDRT LLMPNGYCLD RAPGTNGHHG AAPLAAPPSH VDLCQHYSPH 540

SHQPLPPPDL VWDRQSGPAQ YLHRTCSEAS RHICPYPSPD LTPHNHSHHH PAPAPGRFCC 600

REEDYPEAGP RRQLPLGQRG GASAKRGEMS LHWEQDREAE LQWEREADYW HRRATVASYG 660

SQSHDPPAFT YDPLPSGHPT YPEASRSHAH SHLDLKYSSS SSGYQTPRQV CPCSPYQPSP 720

SESRGYASGY QSESTSPLPP PSSMTGPCSH SNGTANHSHP HPDSQQCYHP DSHTVSSFIK 780

ILVLKSCDSI PSVVPASSDA LRKRGLEGPH HPRLLQEGPQ RRSRRLLHAV RYVRPSHSGP 840

HQQPPALTER SAAAGTNSFQ SWKVSTSSSP AALNLQFITF SSSKIIRVNT KCSLEKMAAP 900

VWESKGLSVL NKKETLPYFL ANKSLLSISR THGQTMHKRL RRFILRKVHT DVLSDNRIYL 960

DEDEYNKVLF ASILVRSESE STSSDKCLRF RFDEVKSFKA GGLITSMCSR SKDKQQNKIM 1020

FLENLSANHH PQRESPSPGG RDFHIRTTDI IDDYESPQLQ DAHHRGNDTV ADSGRSPKSS 1080

SEGSSVQLRD AQSHTDPAPT SPQHSPETTT PSSLDSAASC QAPPPAPAGP PTPTPAEGAA 1140

PPPTSPDSLP QSQSNASVQP NGSSPSQKPL PAAPESSSPT FAPPPSSNSM EGSPVSDPPV 1200

PGFATLSRRL MLSGSDLHHP SYPQNHGALH YHPPAAEHCA PLDTNKLPEK RHHPALSDSA 1260

RPAPGSAQHQ HHVTFSPTVG EVAPPAGLND EVAHGEAASR VSVKFVQDSS RFWYKPGITR 1320

EQAIAALKER EPGTFLIRDS NSFQGAYGLA LKVAVPPPSV HNNKGGDPLE QLVRHFLIET 1380

GPRGVKIKGC QNEPYFGSLS ALVYQHSITP ISLPCALQIP EKDLLGEVQE APPVSNISTA 1440

ADLLKQGAAC NVLYLNSVET ESLTGPQAIA KATEATLGRQ PRPAATVVQF KVTSQGITLT 1500

DSQRRVFFRR HYPVNSVTFS SVDPKDHRWT NPDNTTVRVF GFVAKKPGSL AENVCHLFAE 1560

LDPEQPACAI VNFINKVMLA QRR 1583

Nucleotide Sequence
(FASTA)

CGTGTGATGG AGCGCGTGAT GGAGCGCAAC TATGACTTTG ACCTGACCTA CATCACGGAG 60

AGAATCATCT CCGTCTTCTT TCCTCCGAAG CTGGAGGAGC AGAGGTATCG GATCAACCTG 120

AAGGAAGTGG CGGCCATGCT CAAGTCCAAA CACCAGGACA AATTTCTGCT CCTGAATCTC 180

TCTGAAAGGC GCCATGACAT CACCAGACTG AATCCAAAGG TTCAAGACTT CGGCTGGCCC 240

GACCTGCACG CCCCGCCGCT GGATAAGATC TGCGCCATAT GCAAAGCCAT GGAGACCTGG 300

CTGACCTCCG ACCCTCAGCA TGTTGTGGTC CTGCACTGCA AGGGGAACAA AGGTAAAACT 360

GGCGTGATCA TTGCGGCGTA CATGCACTAC AGCAAGATCT CTGCAGGGGC GGACCAGGCT 420

CTCAGTACTC TTGCCATGAG GAAGTTCTGC GAAGATAAGG TGTCCTCGTC TCTCCAGCCG 480

TCCCAAAACA GGTACATCTA TTACTTTGGA GGTCTCCTCT CTGGAGCCAT AAAGATGAAC 540

AGCAGCCCGT TGTTCCTCCA TCAAGTCCTC ATCCCATCTC TTCCAAACTT CCAGGGGGAA 600

GGAGGTTACT ACCCCTTCCT GAAGATCTAC CAGTGCATGC AGCTGGTCTA CACCTCTGGA 660

ATATATGACC TTCAGGGCAC AGGAGGCCGA CGTCTGTGTG TGACCATCGA ACCGGCGCTG 720

TTGCTGAAGG GTGACATCAT GGTGAAATGC TACCACAGGC AGGCCCAGAG CGCCGACAGA 780

GACACCGTTT TCCGGCTGCA GTTCCACACC TGCACCGTCC ACGGGTCCCA GCTGTGGTTC 840

GGCAAAGGAG AGCTGGATGA AGCTTTCACT GATGAACGTT TTCCTTCTGA CGCCACCGTG 900

GAGTTCATCT TCTCCTCTGG ACCTGAGAGG ATCAAAGGCC GGGAATATCA CAAGAACGAC 960

CCGGCCGTGA CGGTGGACTA CAACACGGCC GACCCGGTGG TCCGCTGGGA TTCCTACGAG 1020

AACTTCAACC AGAGATACCA GGACAGCCTG GAGGACATTG CCCACACCAG AGGTCCTGTA 1080

GATGGAAGCC TGTATGCACA GATCAAGAAG CGCAGAGCAG CTGGTTCCGG TTCCCTCAAC 1140

TCCACCAACG GCAGCAGTCC TGGGGGGCCC CTTGGCGACG ACAGGCCCGA TCACTTCATT 1200

GGCCGGGGAT CTGACTCCGC CCTCTCTGCT CACTCTCTGC ATTTGAACCA AGCATCGACC 1260

CATCCCGACC ACGATGAGGC GCTGCTTCGC CCGCCGCCAC CGCCGACAAG GCAGGAGAGG 1320

GAGGAGCTTG AACGTCTTCT TGGCGGCATC GAGGGCAGCA GAGATGGGGA ACGGGAGACG 1380

GCCATCTTGG ATGATGGAGA CACGCTGGAG AGGACGGGGA CGTTGGGTCT GAGCCGCTCC 1440

TGCTCCTGTC GGGAGGGTTA CCGGTCGCAG CGCTGCGCAG AGCCCGGCTG TGATCGGACC 1500

CTCCTCATGC CCAACGGCTA CTGCCTGGAT CGAGCCCCGG GGACCAACGG CCACCACGGG 1560

GCAGCCCCCC TGGCTGCTCC CCCCTCGCAT GTGGATCTAT GCCAGCATTA CAGCCCCCAC 1620

AGCCACCAGC CCCTCCCACC CCCAGACCTG GTGTGGGACA GGCAGAGTGG CCCGGCTCAG 1680

TACTTGCACC GGACCTGTTC GGAGGCCTCT CGCCACATCT GTCCGTACCC TTCACCGGAT 1740

CTGACCCCCC ACAACCATTC CCATCACCAC CCCGCGCCTG CCCCCGGCCG CTTCTGCTGC 1800

CGGGAGGAGG ACTATCCTGA GGCTGGACCG CGGCGACAGC TTCCACTGGG ACAGAGAGGC 1860

GGAGCTTCAG CAAAGAGAGG AGAGATGTCC CTCCACTGGG AGCAGGACAG GGAGGCGGAG 1920

CTTCAGTGGG AGAGGGAGGC CGATTATTGG CACAGAAGAG CCACCGTAGC CTCCTACGGC 1980

TCGCAGAGCC ACGACCCCCC AGCCTTCACC TATGACCCTC TGCCCTCCGG TCACCCCACC 2040

TATCCTGAAG CATCGAGGTC GCACGCCCAC TCCCACCTGG ATCTGAAGTA CAGCAGCAGC 2100

AGCAGCGGCT ACCAGACGCC CCGCCAGGTC TGCCCCTGCT CGCCATACCA GCCCTCACCG 2160

TCTGAGAGCA GAGGCTACGC CTCCGGTTAC CAGTCCGAGT CAACGTCACC GCTGCCTCCC 2220

CCTTCCTCCA TGACGGGACC CTGCAGCCAC AGCAACGGGA CCGCCAACCA CAGCCACCCC 2280

CATCCAGACT CACAGCAGTG CTACCACCCG GACTCCCACA CCGTTTCATC CTTCATCAAG 2340

ATACTTGTCC TGAAGTCATG TGACTCCATC CCCTCTGTTG TCCCCGCCTC CTCAGATGCT 2400

CTTCGAAAGC GTGGGCTGGA GGGACCACAT CACCCACGGC TCCTTCAAGA GGGTCCACAG 2460

AGACGCTCAC GGCGCCTGCT CCACGCCGTC CGATATGTCC GGCCCTCCCA CTCCGGTCCA 2520

CACCAGCAGC CCCCTGCGCT CACAGAACGT TCTGCTGCTG CCGGGACGAA TTCATTCCAG 2580

TCATGGAAAG TTTCTACTTC TTCCAGTCCA GCAGCACTAA ATCTGCAGTT TATCACTTTT 2640

TCTTCCTCAA AGATAATCAG AGTAAATACA AAATGCAGTT TGGAAAAGAT GGCTGCTCCT 2700

GTCTGGGAAA GCAAAGGCCT TTCCGTGCTC AATAAAAAAG AAACTCTACC GTATTTTTTG 2760

GCAAATAAGT CGCTCCTGAG TATAAGTCGC ACCCATGGCC AAACGATGCA TAAAAGACTT 2820

CGGAGATTTA TACTCAGAAA GGTTCACACT GATGTGTTAT CAGACAACCG AATCTATCTT 2880

GATGAGGATG AATATAATAA AGTATTATTT GCATCCATTC TCGTAAGATC TGAATCTGAA 2940

TCTACATCTT CAGATAAATG CTTGAGATTT CGTTTTGATG AAGTTAAATC CTTTAAGGCA 3000

GGTGGGCTTA TTACGTCAAT GTGCAGTAGA TCAAAGGATA AACAACAAAA TAAAATCATG 3060

TTTTTAGAAA ATCTGTCAGC AAATCATCAT CCTCAGCGTG AAAGCCCCAG TCCAGGAGGG 3120

AGGGACTTCC ACATCCGGAC CACAGACATC ATTGACGACT ACGAGTCTCC GCAGCTGCAG 3180

GATGCACATC ACCGTGGCAA CGACACGGTC GCGGATAGTG GGAGGAGCCC CAAAAGCAGC 3240

TCAGAGGGCT CCTCTGTCCA ACTCAGAGAT GCACAGTCGC ACACAGACCC CGCCCCCACC 3300

TCTCCACAGC ACAGCCCGGA GACGACCACG CCGTCTTCTT TAGATTCCGC TGCGTCCTGT 3360

CAGGCCCCTC CTCCTGCCCC CGCAGGTCCT CCCACACCAA CTCCTGCGGA GGGAGCTGCT 3420

CCGCCCCCCA CATCCCCGGA TTCCCTGCCT CAGAGCCAAA GCAACGCTTC GGTGCAGCCC 3480

AACGGATCCT CCCCCTCTCA GAAACCTCTG CCCGCAGCCC CCGAATCCTC CAGCCCCACC 3540

TTTGCCCCCC CACCGTCATC CAACAGCATG GAGGGCTCCC CGGTGTCCGA CCCTCCGGTT 3600

CCCGGGTTTG CCACTCTGAG CAGGCGTCTG ATGTTGAGTG GGTCAGATCT CCATCACCCC 3660

AGTTACCCTC AGAACCACGG CGCCCTTCAT TACCACCCCC CTGCTGCGGA GCACTGCGCC 3720

CCCCTGGACA CCAACAAGCT GCCGGAGAAA CGGCATCACC CCGCCCTGTC TGACTCCGCC 3780

AGGCCCGCCC CCGGCTCCGC CCAGCATCAG CACCACGTCA CTTTCTCTCC AACTGTGGGG 3840

GAAGTTGCAC CCCCCGCAGG CCTAAATGAC GAGGTGGCGC ACGGTGAGGC GGCGAGCAGA 3900

GTCAGCGTGA AGTTCGTCCA GGACAGTTCC AGGTTCTGGT ACAAACCCGG CATCACCAGA 3960

GAACAAGCCA TCGCCGCTTT GAAGGAGAGA GAACCAGGAA CCTTCCTCAT CAGGGACAGC 4020

AACTCCTTCC AGGGGGCGTA CGGCCTGGCC CTGAAGGTGG CGGTCCCGCC CCCCAGCGTC 4080

CACAACAACA AAGGGGGGGA CCCTCTGGAG CAGCTGGTGA GGCACTTCCT GATAGAAACC 4140

GGCCCCCGAG GAGTCAAGAT CAAAGGCTGC CAGAATGAAC CGTACTTCGG GAGTCTGTCT 4200

GCGCTGGTCT ACCAACACTC CATCACCCCC ATCTCTTTGC CCTGCGCCCT GCAAATCCCA 4260

GAGAAAGATC TCCTGGGGGA GGTGCAGGAG GCCCCGCCTG TCAGTAACAT CAGCACGGCG 4320

GCCGACCTGC TGAAACAGGG AGCAGCCTGC AACGTCCTCT ACCTGAACTC TGTGGAGACA 4380

GAGTCCCTGA CTGGCCCCCA GGCAATCGCC AAGGCAACAG AGGCCACCCT CGGGCGACAG 4440

CCGCGTCCTG CCGCCACCGT GGTCCAGTTC AAGGTGACGT CGCAGGGCAT CACGCTGACG 4500

GACAGCCAGC GCCGGGTCTT CTTCAGGAGG CACTACCCCG TCAACAGCGT CACCTTCAGC 4560

AGCGTCGACC CGAAGGACCA CAGGTGGACT AACCCCGACA ACACCACGGT TAGGGTCTTT 4620

GGGTTTGTCG CCAAGAAGCC CGGCAGCCTG GCGGAGAACG TCTGCCACCT TTTCGCCGAG 4680

TTGGACCCCG AGCAGCCCGC CTGCGCCATC GTCAACTTCA TCAACAAGGT CATGCTGGCG 4740

CAGCGCCGAT AG 4752

Domain Profile

S: 2     rltedgfdldltyvteriiavsfPaeareevyrnnlrevvrlldskhrnkyklynlcser  61

         r++e+++d+dlty+terii+v fP + +e++yr nl+ev+ +l+skh++k++l nl ser

Q: 5     RVMERNYDFDLTYITERIISVFFPPKLEEQRYRINLKEVAAMLKSKHQDKFLLLNL-SER  63

         89******************************************************.***

S: 62    rydltklnakvaefgiedlnaPaleklvsickeldeWlseddenvvvlhckggkgrlGvi  121

         r+d+t+ln+kv++fg++dl+aP+l+k+++ick++++Wl+ d+++vvvlhckg+kg++Gvi

Q: 64    RHDITRLNPKVQDFGWPDLHAPPLDKICAICKAMETWLTSDPQHVVVLHCKGNKGKTGVI  123

         ************************************************************

S: 122   vcayllaseisakadealdtfgerrtredkvagvkqPsqrryvsyfsqllkg  173

         ++ay+++s+isa+ad+al t+++r+++edkv++  qPsq+ry++yf +ll+g

Q: 124   IAAYMHYSKISAGADQALSTLAMRKFCEDKVSSSLQPSQNRYIYYFGGLLSG  175

         *************************************************986

Domain Sequence
(FASTA)

RVMERNYDFD LTYITERIIS VFFPPKLEEQ RYRINLKEVA AMLKSKHQDK FLLLNLSERR 60

HDITRLNPKV QDFGWPDLHA PPLDKICAIC KAMETWLTSD PQHVVVLHCK GNKGKTGVII 120

AAYMHYSKIS AGADQALSTL AMRKFCEDKV SSSLQPSQNR YIYYFGGLLS G 171

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

KEGG

InterPros

IPR008973	; C2_Ca/lipid-bd_dom_CaLB.
IPR011993	; PH_like_dom.
IPR014019	; Phosphatase_tensin-typ.
IPR013625	; PTB.
IPR006020	; PTyr_interaction_dom.
IPR000980	; SH2.
IPR014020	; Tensin_phosphatase_C2-dom.

Pfam

PF08416	; PTB; 1.
PF10409	; PTEN_C2; 1.
PF00017	; SH2; 1.

SMARTs

SM00462	; PTB; 1.
SM00252	; SH2; 1.

Prosites

PS51182	; C2_TENSIN; 1.
PS51181	; PPASE_TENSIN; 1.
PS50001	; SH2; 1.

Prints

Created Date

20-Feb-2013