EKS-ORL-00300

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORL-00300

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	336.7	9.0E-101	31	283	253

Status

Unreviewed

Ensembl Protein

ENSORLP00000002164

UniProt Accession

H2L8J4;

Protein Name

Protein Synonyms/Alias

Gene Name

PRKAA2

Gene Synonyms/Alias

PRKAA2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSORLG00000001742	ENSORLP00000002164	ENSORLT00000002165
ENSORLG00000001742	ENSORLP00000002167	ENSORLT00000002168

Organism

Oryzias latipes

Functional Description

Protein Length

570

Protein Sequence
(FASTA)

ARAPSSAAVG NGKMAERQQQ KHEGRVKIGH YILGDTLGVG TFGKVKIGEH QLTGHKVAVK 60

ILNRQRIRSL DVVGKIKREI QNLKLFRHPH IIKLYQVIST PTDFFMVMEY VSGGELFDYI 120

CKNGRVEDPE ARRLFQQIIS AVDYCHRHMV VHRDLKPENV LLDANKNAKI ADFGLSNMMS 180

DGEFLRTSCG SPNYAAPEVI SGRLYAGPEV DIWSCGVILY ALLCGTLPFD DEHVPTLFKK 240

IRGGVFYMPE YLTRSVASLL MLMLQVDPLK RATIKDIREH DWFKQDLPGY LFPEDSSYDC 300

TVLDEEAVRE VCEKFECTDS EVVSSLYSGD PQDQLAVAYH LIIDNRRIMT QASEFYLASS 360

PPQGSFIEEG MPLPPGVKPH PERMPPLMAD SPKSRCPLDA LNTTRPKPLA VKKAKWHLGI 420

RSQSRPHDIM TEVYRAMRQL AFDWKVVNPY HLRVRRKNPV TGNLVKMSLQ LYQVDNRSYL 480

LDFKSIDDDI LEAVGFKSGS STPQRSGSTA GLHRPRLSID FASPANDVPQ LSSSLPGSLS 540

GISPLLSPRQ GSHTMDFFEM CASLITTLAR 570

Nucleotide Sequence
(FASTA)

GCGCGCGCAC CGAGCAGCGC GGCCGTCGGT AACGGGAAGA TGGCAGAGCG GCAACAGCAG 60

AAGCACGAAG GCAGGGTCAA GATCGGACAC TACATCCTCG GCGACACGCT GGGAGTGGGG 120

ACGTTTGGCA AAGTGAAGAT TGGAGAGCAT CAGCTGACTG GACATAAAGT GGCCGTGAAG 180

ATCCTGAACA GACAGAGGAT CCGAAGCCTC GATGTTGTGG GAAAGATCAA ACGGGAGATC 240

CAGAACCTCA AACTCTTCAG ACACCCGCAC ATCATCAAGC TATACCAGGT AATCAGTACT 300

CCAACAGATT TCTTCATGGT GATGGAGTAC GTGTCTGGAG GGGAGCTGTT TGACTACATC 360

TGCAAAAATG GGCGGGTGGA GGACCCAGAA GCTCGGCGTC TTTTCCAGCA GATCATTTCA 420

GCCGTGGACT ACTGCCACCG GCACATGGTG GTGCACAGAG ACCTCAAACC TGAGAACGTC 480

TTGCTTGATG CCAATAAAAA TGCCAAAATT GCAGACTTTG GACTGTCCAA CATGATGTCA 540

GACGGGGAAT TCCTGCGAAC AAGCTGCGGC TCACCAAACT ATGCAGCTCC AGAGGTCATC 600

TCCGGAAGGC TGTACGCAGG CCCGGAGGTG GACATCTGGA GCTGCGGGGT GATCCTGTAC 660

GCCCTGCTGT GTGGCACCCT GCCCTTTGAC GATGAGCATG TTCCCACACT GTTTAAGAAG 720

ATCAGAGGAG GCGTTTTTTA CATGCCAGAG TACCTGACCC GCTCTGTGGC CTCACTGCTA 780

ATGCTCATGC TACAGGTGGA TCCGCTGAAA AGAGCCACCA TCAAAGACAT CAGGGAACAT 840

GATTGGTTTA AGCAGGACCT GCCAGGTTAC CTGTTCCCGG AGGACTCGTC GTACGATTGC 900

ACTGTGTTGG ATGAGGAAGC TGTTCGAGAA GTGTGTGAGA AGTTTGAATG CACAGACTCT 960

GAAGTGGTGT CCAGCCTCTA CAGTGGAGAT CCACAGGATC AGTTAGCGGT GGCGTATCAC 1020

CTCATCATAG ATAATCGACG CATCATGACG CAGGCCAGCG AGTTCTACTT GGCATCCAGT 1080

CCTCCACAGG GCTCTTTTAT AGAGGAGGGT ATGCCATTGC CCCCTGGGGT CAAACCCCAC 1140

CCAGAGAGGA TGCCTCCACT TATGGCTGAC AGCCCCAAGT CTCGATGTCC TCTGGATGCT 1200

CTCAACACCA CCCGGCCTAA ACCGCTAGCA GTGAAGAAAG CCAAGTGGCA CCTGGGGATC 1260

AGGAGTCAGA GCAGACCCCA TGACATCATG ACGGAGGTGT ACCGGGCTAT GAGGCAACTC 1320

GCTTTTGACT GGAAGGTGGT GAACCCATAC CATCTGCGTG TGCGGAGGAA GAACCCAGTG 1380

ACGGGAAACC TGGTGAAAAT GAGCCTGCAG CTCTACCAAG TGGATAACAG ATCCTACCTC 1440

CTTGACTTCA AAAGCATTGA TGATGACATC CTGGAAGCAG TGGGCTTTAA ATCGGGGTCG 1500

TCCACTCCTC AGAGGTCCGG CTCCACTGCA GGTCTCCACA GACCCAGGCT GAGCATTGAC 1560

TTTGCAAGCC CAGCCAACGA TGTGCCTCAG CTTAGCTCCT CCCTCCCGGG ATCGCTGTCC 1620

GGCATTTCCC CCCTCCTCTC CCCGCGGCAG GGATCGCACA CCATGGACTT CTTTGAAATG 1680

TGTGCCAGTC TGATCACCAC GCTTGCGCGC TGA 1713

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkkl.seeslekikrEieilkklkhpn  59

         y l++tlG g+fgkVk  +h++t++kvavKi++++++ s + + kikrEi+ lk ++hp+

Q: 31    YILGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQRIrSLDVVGKIKREIQNLKLFRHPH  90

         8899********************************96667788****************

S: 60    iikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgi  119

         iikl++vi+t +++++v+ey+sggeLfdyi ++gr++  ear+lf+q++sav+Y+h++ +

Q: 91    IIKLYQVISTPTDFFMVMEYVSGGELFDYICKNGRVEDPEARRLFQQIISAVDYCHRHMV  150

         ************************************************************

S: 120   vHrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkv  179

         vHrDlKpeN+lld+++n kiaDFGl+n++++g+ l+t+cGsp+YaaPe+++g+ Y gp+v

Q: 151   VHRDLKPENVLLDANKNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEV  210

         ************************************************************

S: 180   DvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpek  239

         D+Ws+Gv+Lyal++g+lPfd+e++ +l++ki  g + +p++l+++++sLl  +L+vdp k

Q: 211   DIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYMPEYLTRSVASLLMLMLQVDPLK  270

         ************************************************************

S: 240   Ratieeilkhewl  252

         Rati++i++h w+

Q: 271   RATIKDIREHDWF  283

         ************7

Domain Sequence
(FASTA)

YILGDTLGVG TFGKVKIGEH QLTGHKVAVK ILNRQRIRSL DVVGKIKREI QNLKLFRHPH 60

IIKLYQVIST PTDFFMVMEY VSGGELFDYI CKNGRVEDPE ARRLFQQIIS AVDYCHRHMV 120

VHRDLKPENV LLDANKNAKI ADFGLSNMMS DGEFLRTSCG SPNYAAPEVI SGRLYAGPEV 180

DIWSCGVILY ALLCGTLPFD DEHVPTLFKK IRGGVFYMPE YLTRSVASLL MLMLQVDPLK 240

RATIKDIREH DWF 253

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR001772	; Kinase-assoc_KA1.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013