EKS-ORL-00278

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORL-00278

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE7	318.8	3.3E-95	168	419	252

Status

Unreviewed

Ensembl Protein

ENSORLP00000002686

UniProt Accession

H2L9Y6;

Protein Name

Protein Synonyms/Alias

Gene Name

MAP2K5

Gene Synonyms/Alias

MAP2K5;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSORLG00000002158	ENSORLP00000002688	ENSORLT00000002689
ENSORLG00000002158	ENSORLP00000002686	ENSORLT00000002687
ENSORLG00000002158	ENSORLP00000002692	ENSORLT00000002693

Organism

Oryzias latipes

Functional Description

Protein Length

446

Protein Sequence
(FASTA)

LYMLISNSMF EMDNEAIVIR IKTPLGDMDS SVDSASLLNF NDLMVAIRDV MPEATVTAFE 60

YEDEVGDRIT VRSDEELKAM LSYYLNTVNE QRMNGLLPDP LQIFPRAGKT PGIRNIHGLK 120

VNTRPNPESD STHAVSDSIA NNSLKKSSAE LKKILTNGQQ INAQDIHYQE LLGHGNGGTV 180

YKAYHVLGNR VLAVKVIPLD ITVELQKQIM SELEILYKCD SPYIITFFSA FFVENRISIC 240

TEFMDGGSLD VYKTIPELVL GRIAVAVVKG LTYLWSLKIL HRDVKPSNML VNTRGQVKLC 300

DFGVSTQLVN SIAKTYVGTN AYMAPERISG EQYGIHADVW SVGISFMELA LGMFPYPQIQ 360

KNQGSLIPLQ LLQCIVDEDP PVLPVGEFSE MFVHFITLCM QRNPKERPAP NNLMDHPFII 420

QFNDGNAEVV SMWVCRSLEE RRTQQA 446

Nucleotide Sequence
(FASTA)

TTATATATGT TAATTTCAAA TAGCATGTTT GAAATGGACA ACGAGGCTAT AGTAATCCGC 60

ATAAAAACAC CGCTGGGAGA CATGGACTCG TCCGTGGACT CTGCATCTCT TCTGAACTTC 120

AATGACTTGA TGGTCGCAAT CAGGGATGTG ATGCCAGAAG CTACTGTCAC GGCATTTGAA 180

TATGAAGATG AGGTGGGAGA CAGAATCACG GTCAGAAGTG ATGAAGAACT CAAAGCCATG 240

TTGTCATACT ACTTAAACAC AGTAAATGAA CAACGCATGA ATGGACTGCT GCCAGATCCT 300

CTACAAATTT TTCCAAGAGC CGGCAAGACT CCAGGGATCC GGAACATACA TGGCCTGAAG 360

GTCAATACTA GACCCAACCC TGAAAGTGAC AGCACTCATG CTGTATCTGA CTCCATAGCC 420

AACAACAGCT TAAAAAAGTC ATCAGCTGAA CTCAAGAAGA TCTTGACAAA CGGGCAGCAG 480

ATAAATGCCC AAGATATCCA CTATCAAGAG CTGCTTGGCC ATGGAAATGG AGGCACAGTT 540

TACAAAGCGT ACCATGTTCT TGGCAATCGG GTTTTAGCTG TCAAGGTCAT TCCTCTGGAT 600

ATTACTGTGG AGTTACAAAA GCAAATTATG TCAGAATTAG AAATTCTTTA CAAGTGCGAT 660

TCCCCGTACA TCATCACGTT CTTCAGTGCC TTCTTTGTAG AGAACAGGAT ATCCATATGC 720

ACAGAATTTA TGGATGGTGG ATCTTTGGAT GTCTACAAAA CAATTCCAGA GCTTGTGTTG 780

GGGAGGATCG CAGTGGCGGT AGTCAAAGGC CTGACATATC TGTGGAGCCT GAAGATACTT 840

CACAGAGATG TCAAGCCTTC CAATATGCTG GTGAACACCC GAGGACAAGT CAAGCTGTGT 900

GACTTTGGTG TCAGCACACA GTTAGTAAAC TCCATCGCAA AGACATATGT GGGAACCAAC 960

GCATATATGG CACCAGAGAG AATATCAGGA GAACAGTATG GTATACATGC AGATGTCTGG 1020

AGTGTTGGGA TCTCTTTTAT GGAGCTGGCA CTGGGAATGT TCCCCTATCC ACAAATTCAG 1080

AAAAATCAAG GATCCTTAAT ACCTCTCCAG TTACTGCAAT GCATCGTTGA TGAGGACCCT 1140

CCAGTGCTTC CTGTTGGAGA GTTCAGTGAA ATGTTTGTTC ACTTCATCAC TCTCTGTATG 1200

CAACGAAACC CAAAGGAGAG ACCTGCACCC AACAACCTAA TGGATCATCC CTTCATCATC 1260

CAGTTTAATG ATGGAAATGC AGAGGTGGTG TCCATGTGGG TTTGCCGCTC TCTGGAGGAG 1320

AGGCGCACTC AGCAGGCT 1338

Domain Profile

S: 3     kleelGaGnggvVekvlhkksgkilavKtirleikkeeqkqilrelevlkkssnspyivk  62

           e lG+Gngg+V+k+ h   +++lavK i l+i+ e qkqi++ele+l k+ +spyi++

Q: 168   YQELLGHGNGGTVYKAYHVLGNRVLAVKVIPLDITVELQKQIMSELEILYKC-DSPYIIT  226

         56789***********************************************.*******

S: 63    fyGafvsegdvsicmelmdgtsldkvlkkvlekkkripekvlgkiavavvkaleylkekl  122

         f+ af+ e+++sic+e+mdg+sld v+k+       ipe vlg+iavavvk+l+yl+ +l

Q: 227   FFSAFFVENRISICTEFMDGGSLD-VYKT-------IPELVLGRIAVAVVKGLTYLW-SL  277

         ************************.6875.......9********************.78

S: 123   kiiHRDvKPsNiLvnskGevKlCDFGvsgqlvdsiAksavGtksYmaPEriegkkkYsvk  182

         ki+HRDvKPsN+Lvn++G+vKlCDFGvs+qlv+siAk++vGt++YmaPEri+g ++Y ++

Q: 278   KILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISG-EQYGIH  336

         *****************************************************.******

S: 183   sdvWslGltlvelatgrypyeklke......ilellkaivneeppklpeeefseefqefv  236

         +dvWs+G++++ela g +py++ ++      +l+ll++iv+e+pp+lp  efse f++f+

Q: 337   ADVWSVGISFMELALGMFPYPQIQKnqgsliPLQLLQCIVDEDPPVLPVGEFSEMFVHFI  396

         ***********************9999*********************************

S: 237   skClkkdekeRpklkellkhafi  259

         + C+++++keRp  ++l++h+fi

Q: 397   TLCMQRNPKERPAPNNLMDHPFI  419

         **********************7

Domain Sequence
(FASTA)

YQELLGHGNG GTVYKAYHVL GNRVLAVKVI PLDITVELQK QIMSELEILY KCDSPYIITF 60

FSAFFVENRI SICTEFMDGG SLDVYKTIPE LVLGRIAVAV VKGLTYLWSL KILHRDVKPS 120

NMLVNTRGQV KLCDFGVSTQ LVNSIAKTYV GTNAYMAPER ISGEQYGIHA DVWSVGISFM 180

ELALGMFPYP QIQKNQGSLI PLQLLQCIVD EDPPVLPVGE FSEMFVHFIT LCMQRNPKER 240

PAPNNLMDHP FI 252

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>