EKS-ORL-00238

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORL-00238

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/MAST	526.4	1.8E-158	388	661	274

Status

Unreviewed

Ensembl Protein

ENSORLP00000003364

UniProt Accession

H2LBT5;

Protein Name

Protein Synonyms/Alias

Gene Name

MAST4

Gene Synonyms/Alias

MAST4;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSORLG00000002700	ENSORLP00000003368	ENSORLT00000003369
ENSORLG00000002700	ENSORLP00000003366	ENSORLT00000003367
ENSORLG00000002700	ENSORLP00000003364	ENSORLT00000003365

Organism

Oryzias latipes

Functional Description

Protein Length

731

Protein Sequence
(FASTA)

MKAQRERLRI PGLTLDLTPR SLSPTPTSPC SPCSPLHAFH FWSCRTSNRK SLIGSGQSSG 60

LTRPHSPLSS LTAGTSPQDS PRNFSPSASA HFSFARRTDG RRWSLASLPS SGYGTNTPSS 120

TISSSCSSQE KLHQLPFQPT PDELHFLSKH FCTESISGEE CRRATAMRPR SRSLSPGRSP 180

SCYDHEIIMM NHVYKERFPK ATAQMEEKIQ EIIRSNSPES VPPLADGVLG FAHHQIIELA 240

RDCLEKSRFG HITSSYFCEL TDKLERLVQE STERSESEEV NFIKELVKKI LIVIARPARL 300

LECLEFDPEE FYHLLEAAEG HAKEGQGIKT DIPRYIISQL GLTRDPLEEI AQLTSCDSGI 360

AETPETDDSS QSIGTALRSR RKPCELDFEM IKLISNGAYG AVYLVRHKET KQRFAMKKIN 420

KQNLMLRNQI QQAFVERDIL TFAENPFVVS MYCSFETRRH LCMVMEYVEG GDCATLLKNM 480

GPLPVDMARM YFAETVLALE YLHNYGIVHR DLKPDNLLVT SMGHIKLTDF GLSKVGLMNM 540

TTNLYEGHIE KDAREFSDKQ VCGTPEYIAP EVILRQGYGK PVDWWAMGII LYEFLVGCVP 600

FFGDTPEELF GQVISDEINW PEGEEAPPLD AQELVTLLLR QNPLERLGTG GAAEVKQHQF 660

FHHLDWNGLL RQKAEFIPQL ESEDDTSYFD TRSERYHHLE TEEDDTNDED FSVDLRQFSS 720

CSHRFSKVYS S 731

Nucleotide Sequence
(FASTA)

ATGAAAGCCC AGCGGGAGAG GCTGAGGATC CCAGGGCTGA CGCTGGACCT CACTCCCAGA 60

AGCTTGAGCC CTACTCCCAC TAGCCCCTGC AGTCCGTGCA GCCCGCTGCA CGCTTTCCAT 120

TTCTGGAGCT GTAGAACCAG CAACAGGAAG AGCCTGATCG GAAGCGGGCA GTCGTCCGGT 180

CTCACCCGGC CTCACTCCCC TCTGTCGTCT CTCACAGCAG GAACAAGCCC ACAAGACAGC 240

CCTCGAAACT TCTCCCCCAG TGCCTCTGCC CACTTCTCCT TCGCTCGAAG GACTGATGGC 300

CGCCGCTGGT CCTTGGCCTC CCTTCCCTCC TCTGGATATG GAACCAACAC CCCCAGTTCC 360

ACCATTTCTT CATCCTGTTC ATCACAGGAG AAGCTGCACC AGCTGCCCTT CCAGCCCACC 420

CCCGATGAGC TCCACTTCCT CTCCAAGCAT TTCTGCACCG AGAGCATCTC AGGGGAGGAA 480

TGCCGCCGAG CGACGGCCAT GCGACCTCGC TCCCGCAGCC TCAGCCCTGG AAGATCTCCG 540

TCCTGCTACG ACCACGAGAT CATCATGATG AATCACGTCT ACAAGGAGCG GTTCCCCAAG 600

GCCACGGCTC AGATGGAGGA GAAGATTCAG GAGATCATCC GCAGCAACTC CCCAGAGAGC 660

GTCCCGCCTC TGGCGGACGG TGTGCTCGGC TTCGCCCACC ATCAGATCAT CGAACTGGCC 720

CGCGACTGTC TGGAAAAGAG TCGGTTCGGA CACATCACGT CCAGCTACTT CTGTGAGCTC 780

ACAGACAAGC TGGAGAGGCT CGTTCAAGAG TCCACAGAGA GGTCAGAAAG CGAGGAGGTG 840

AACTTCATCA AAGAGCTGGT GAAGAAGATC CTCATCGTGA TAGCTCGACC CGCTCGGCTG 900

CTGGAGTGTT TGGAGTTTGA CCCGGAGGAG TTTTACCACC TCCTGGAGGC AGCTGAAGGA 960

CACGCCAAAG AGGGCCAGGG CATCAAGACG GACATCCCTC GGTACATCAT CAGTCAGCTG 1020

GGGCTCACCA GAGACCCCCT GGAAGAAATC GCCCAGCTGA CCAGCTGTGA CAGCGGTATC 1080

GCAGAAACCC CAGAGACAGA TGATTCTTCT CAGAGCATCG GCACCGCGCT GCGATCCCGA 1140

AGGAAACCCT GTGAGCTCGA CTTTGAGATG ATAAAGCTCA TCAGCAACGG AGCCTATGGA 1200

GCTGTTTATT TAGTTCGACA CAAGGAAACC AAGCAGCGAT TTGCCATGAA GAAGATCAAC 1260

AAGCAGAATC TGATGCTGAG GAATCAAATA CAGCAGGCCT TCGTGGAGAG GGACATCCTC 1320

ACCTTCGCCG AGAACCCCTT TGTTGTGTCC ATGTATTGCT CATTTGAGAC GCGCCGGCAC 1380

CTGTGCATGG TGATGGAGTA CGTTGAAGGG GGAGACTGTG CCACCCTGCT GAAGAACATG 1440

GGTCCGCTGC CCGTGGACAT GGCCCGCATG TACTTTGCAG AAACCGTCTT GGCTTTGGAG 1500

TATCTCCACA ACTACGGCAT CGTCCACAGA GATCTCAAAC CTGACAATCT TCTGGTGACC 1560

TCGATGGGGC ACATCAAGCT GACAGATTTT GGTCTCTCCA AAGTGGGGCT GATGAACATG 1620

ACCACCAACC TGTACGAAGG TCACATTGAG AAAGACGCCC GAGAGTTCTC CGACAAGCAG 1680

GTTTGTGGAA CCCCGGAGTA CATCGCTCCT GAGGTCATTC TGAGACAAGG CTACGGGAAG 1740

CCGGTGGACT GGTGGGCCAT GGGAATAATC CTCTACGAGT TCCTCGTCGG CTGTGTGCCT 1800

TTTTTTGGAG ACACTCCAGA GGAGCTGTTT GGACAAGTTA TCAGCGATGA GATCAACTGG 1860

CCTGAAGGGG AGGAAGCGCC CCCTCTGGAC GCTCAGGAGC TAGTCACCTT GCTGCTCAGG 1920

CAGAACCCTC TGGAAAGGCT GGGCACAGGT GGCGCTGCGG AAGTGAAGCA GCATCAGTTC 1980

TTCCACCACC TGGACTGGAA CGGCCTGCTG AGGCAGAAGG CTGAGTTCAT TCCCCAGCTG 2040

GAGTCTGAGG ATGACACCAG CTACTTCGAC ACTCGCTCTG AGAGGTACCA CCACCTGGAA 2100

ACGGAGGAGG ACGACACAAA CGATGAGGAC TTCAGCGTGG ACCTGCGGCA GTTCTCCTCC 2160

TGCTCCCACA GATTCTCCAA GGTTTACAGC AGC 2193

Domain Profile

S: 1     feiiklisrGayGavylvrhketrkrfavkkikkqdlilknqvqqvfaerdilalaenpf  60

         fe+iklis+GayGavylvrhket++rfa+kki+kq+l+l+nq+qq+f+erdil++aenpf

Q: 388   FEMIKLISNGAYGAVYLVRHKETKQRFAMKKINKQNLMLRNQIQQAFVERDILTFAENPF  447

         89**********************************************************

S: 61    vvslyysletrrnlylvmeyveGGdvksllkniGaldvemarlyiaevvlaleylhryGi  120

         vvs+y+s+etrr+l++vmeyveGGd+++llkn+G+l+v+mar+y+ae+vlaleylh+yGi

Q: 448   VVSMYCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARMYFAETVLALEYLHNYGI  507

         ************************************************************

S: 121   vhrdlkPdnllitseGhikltdfGlskvglmslttnlyegyidkdarefldkqvcgtPey  180

         vhrdlkPdnll+ts+GhikltdfGlskvglm++ttnlyeg+i+kdaref+dkqvcgtPey

Q: 508   VHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMNMTTNLYEGHIEKDAREFSDKQVCGTPEY  567

         ************************************************************

S: 181   iaPevilrqgygkpvdwwalgiilyeflvgivpffgdtpeelfaqvlsdeivwPekdeal  240

         iaPevilrqgygkpvdwwa+giilyeflvg+vpffgdtpeelf+qv+sdei+wPe++ea

Q: 568   IAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEINWPEGEEAP  627

         ************************************************************

S: 241   ssealelisellesnPrerlgtgsaaevkqhefl  274

         + +a+el++ ll++nP erlgtg+aaevkqh+f+

Q: 628   PLDAQELVTLLLRQNPLERLGTGGAAEVKQHQFF  661

         ********************************97

Domain Sequence
(FASTA)

FEMIKLISNG AYGAVYLVRH KETKQRFAMK KINKQNLMLR NQIQQAFVER DILTFAENPF 60

VVSMYCSFET RRHLCMVMEY VEGGDCATLL KNMGPLPVDM ARMYFAETVL ALEYLHNYGI 120

VHRDLKPDNL LVTSMGHIKL TDFGLSKVGL MNMTTNLYEG HIEKDAREFS DKQVCGTPEY 180

IAPEVILRQG YGKPVDWWAM GIILYEFLVG CVPFFGDTPE ELFGQVISDE INWPEGEEAP 240

PLDAQELVTL LLRQNPLERL GTGGAAEVKQ HQFF 274

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Caenorhabditis elegans"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Loxodonta africana"; ?>Mus musculus"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0000287	; F:magnesium ion binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR015022	; MA_Ser/Thr_Kinase_dom.
IPR023142	; MAST_pre-PK_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF08926	; DUF1908; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013