EPS-ORL-00087

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-ORL-00087

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/PTEN	254.5	8.9E-76	172	346	175

Status

Unreviewed

Ensembl Protein

ENSORLP00000005861

UniProt Accession

H2LIN4;

Protein Name

Protein Synonyms/Alias

Gene Name

TPTE

Gene Synonyms/Alias

TPTE;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSORLG00000004658	ENSORLP00000005861	ENSORLT00000005862
ENSORLG00000004658	ENSORLP00000005864	ENSORLT00000005865

Organism

Oryzias latipes

Functional Description

Protein Length

491

Protein Sequence
(FASTA)

MEDAKVEIDN GKEESALPDT LYHNIQRAIT PFVMSFGFRL FGVVLIIVDF VLVIVDFSLA 60

SKSREVAKAL EAVSLSISFF FLADVLLRVY VEGFKVYFRS KLNIVDACVV VLTLVVTMVY 120

TFSDLSGVSL IPRVVNFFRF LRIIILVRVF RLAAQKKELE KVTRRMISEN KRRYQKDGFD 180

LDLTYVTDRV IAMSFPSSGK QAFYRNPIKE VARFLDTKHE GHYKVFNLCS EKGYDPQHFH 240

YRVERVFIDD HNVPALEDML KFTASVREWM SADPQNVIAI HCKGGKGRTG TMVCTWLIDS 300

DQFESAQDSL EYFGERRTDK TRSSKFQGVE TPSQSRYVGY YEVMKNKFNR QLPPPQSLRI 360

KSLRIHSIAG VGRGDGSDLK VKIIVRGELV FQCVCAQQEN CTVFPDAGSN AAVISLQNGP 420

VVEGDVKVMF ESSAGLPKGY EDVPFYFWFN TSFVEHNKLF FPREELDNPH KPKTWNLYKE 480

DFGITVYFLP V 491

Nucleotide Sequence
(FASTA)

ATGGAAGATG CAAAAGTGGA GATCGATAAT GGAAAGGAGG AGAGTGCACT CCCAGACACT 60

CTTTATCACA ACATCCAGAG AGCGATAACT CCGTTTGTCA TGTCATTTGG ATTTCGCCTC 120

TTTGGAGTGG TGCTGATCAT CGTGGACTTC GTTCTTGTGA TTGTGGACTT CTCGTTGGCC 180

TCTAAGAGCA GAGAGGTTGC AAAGGCTTTG GAAGCCGTCT CCCTCAGCAT CTCCTTTTTC 240

TTCCTGGCTG ATGTCCTCCT GCGAGTCTAT GTGGAAGGCT TCAAGGTGTA CTTCCGCTCC 300

AAGTTGAACA TCGTAGATGC CTGTGTCGTG GTGTTGACGC TGGTGGTCAC CATGGTCTAC 360

ACCTTCAGTG ATCTGTCGGG TGTCAGCCTC ATTCCCAGGG TTGTCAACTT CTTTCGCTTC 420

TTGAGGATAA TAATCCTTGT GAGGGTTTTC CGACTGGCAG CTCAGAAAAA GGAGTTGGAG 480

AAAGTCACCA GGAGGATGAT TTCTGAGAAC AAGAGGCGCT ACCAGAAGGA TGGATTTGAC 540

CTTGATCTGA CGTACGTCAC AGATCGTGTC ATAGCGATGT CATTTCCCTC CTCTGGGAAG 600

CAGGCCTTTT ATAGAAATCC AATCAAGGAG GTGGCCAGGT TTCTGGACAC TAAACATGAA 660

GGCCATTACA AAGTTTTTAA CCTTTGCAGT GAGAAAGGCT ATGACCCTCA GCACTTCCAC 720

TACAGGGTTG AAAGGGTCTT CATTGACGAC CACAATGTCC CTGCTTTGGA GGATATGCTG 780

AAATTCACAG CGAGCGTCAG GGAGTGGATG TCTGCTGACC CCCAAAACGT CATCGCCATT 840

CACTGTAAAG GAGGCAAAGG TCGCACAGGC ACCATGGTCT GCACCTGGCT CATCGACAGC 900

GACCAGTTCG AGAGCGCACA GGACAGCCTT GAGTATTTTG GGGAGAGGAG GACGGACAAG 960

ACGCGGAGCT CTAAGTTCCA AGGGGTGGAG ACTCCCTCTC AGAGTCGTTA TGTTGGATAC 1020

TACGAGGTTA TGAAGAACAA GTTCAACAGA CAGCTGCCTC CACCTCAAAG CCTCCGAATC 1080

AAAAGCCTTC GCATCCACTC CATAGCAGGT GTGGGTAGAG GTGATGGCAG CGATCTGAAG 1140

GTGAAGATAA TCGTGAGGGG GGAGCTGGTA TTTCAGTGCG TGTGTGCCCA ACAAGAAAAC 1200

TGCACAGTGT TTCCTGACGC AGGCAGCAAT GCAGCCGTCA TCAGCCTGCA GAACGGGCCT 1260

GTGGTTGAAG GGGATGTGAA GGTTATGTTT GAGTCGAGTG CTGGGCTTCC AAAAGGATAT 1320

GAAGATGTTC CCTTCTACTT CTGGTTCAAT ACTTCTTTTG TGGAGCATAA TAAGCTGTTT 1380

TTTCCCAGAG AAGAACTGGA TAACCCCCAC AAACCAAAAA CATGGAACCT GTACAAGGAG 1440

GACTTTGGGA TCACCGTTTA CTTTTTGCCA GTCTAA 1476

Domain Profile

S: 1     rrltedgfdldltyvteriiavsfPaeareevyrnnlrevvrlldskhrnkyklynlcse  60

         rr+++dgfdldltyvt+r+ia+sfP+++++ +yrn+++ev+r+ld kh+++yk++nlcse

Q: 172   RRYQKDGFDLDLTYVTDRVIAMSFPSSGKQAFYRNPIKEVARFLDTKHEGHYKVFNLCSE  231

         79**********************************************************

S: 61    rrydltklnakvaefgiedlnaPaleklvsickeldeWlseddenvvvlhckggkgrlGv  120

         + yd+++++ +v+++ i+d+n+Pale +  ++  + eW+s+d++nv+++hckggkgr+G+

Q: 232   KGYDPQHFHYRVERVFIDDHNVPALEDMLKFTASVREWMSADPQNVIAIHCKGGKGRTGT  291

         ************************************************************

S: 121   ivcayllaseisakadealdtfgerr...tredkvagvkqPsqrryvsyfsqllk  172

         +vc++l+ s+ + +a+++l++fgerr   tr+ k++gv++Psq ryv y+  +++

Q: 292   MVCTWLIDSDQFESAQDSLEYFGERRtdkTRSSKFQGVETPSQSRYVGYYEVMKN  346

         *************************988899*******************98876

Domain Sequence
(FASTA)

RRYQKDGFDL DLTYVTDRVI AMSFPSSGKQ AFYRNPIKEV ARFLDTKHEG HYKVFNLCSE 60

KGYDPQHFHY RVERVFIDDH NVPALEDMLK FTASVREWMS ADPQNVIAIH CKGGKGRTGT 120

MVCTWLIDSD QFESAQDSLE YFGERRTDKT RSSKFQGVET PSQSRYVGYY EVMKN 175

Keyword

Complete proteome; Ion transport; Ionic channel; Membrane; Reference proteome; Transmembrane; Transport.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016021	; C:integral to membrane
GO:0005216	; F:ion channel activity
GO:0004725	; F:protein tyrosine phosphatase activity
GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0035335	; P:peptidyl-tyrosine dephosphorylation

KEGG

InterPros

IPR008973	; C2_Ca/lipid-bd_dom_CaLB.
IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR005821	; Ion_trans_dom.
IPR014019	; Phosphatase_tensin-typ.
IPR014020	; Tensin_phosphatase_C2-dom.
IPR016130	; Tyr_Pase_AS.

Pfam

PF00782	; DSPc; 1.
PF00520	; Ion_trans; 1.
PF10409	; PTEN_C2; 1.

SMARTs

Prosites

PS51182	; C2_TENSIN; 1.
PS51181	; PPASE_TENSIN; 1.
PS00383	; TYR_PHOSPHATASE_1; 1.

Prints

Created Date

20-Feb-2013