EKS-ORL-00285

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORL-00285

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/PDK1	403.1	7.4E-121	92	352	261

Status

Unreviewed

Ensembl Protein

ENSORLP00000009714

UniProt Accession

H2LUD7;

Protein Name

Protein Synonyms/Alias

Gene Name

PDPK1

Gene Synonyms/Alias

PDPK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSORLG00000007757	ENSORLP00000009714	ENSORLT00000009715
ENSORLG00000007757	ENSORLP00000009715	ENSORLT00000009716

Organism

Oryzias latipes

Functional Description

Protein Length

565

Protein Sequence
(FASTA)

MARATSQLYD VVPIQPNVVI CSCSHPSMVR NHPDSCSPLA IPGASSRHCS GMEGPAAEAC 60

AVGAPANSQS SEACKQPAIQ PAQPRKKKPE DFKFGKILGE GSFSTVVLAR EHATGKEFAI 120

KILEKRHIMK ENKVQYVKRE RDLMSSLDHP FFVKLYFTFQ DDEKLYFGLS YAKNGELLKY 180

IRKIGSFDET CTRFYSAEIV CALEYLHIKG IIHRDLKPEN ILLSEDMHIQ ITDFGTAKQL 240

SSDSKQARAN SFVGTAQYVS PELLTEKSAC KSSDLWALGC IIYQLVAGLP PFRAGNEYLI 300

FQKIIKLEYE FPEKFFPKAK DLVEQLLSLD PSKRIGCEEM GGYEPLKQHP FFDTISWCDL 360

HLQTPPKLTP YLPAMSEDDE DCYGNYDDLL SQFSNMQVAQ SSSSQSLSPH DSTPPQRSSS 420

NIEQYIHDLD SNSFELDLQF TEEEKRLLLD KQTIGNPWHQ FVENNLILKM GPVDKRKGLF 480

ARRRQLLLTE GPHLYYVDPV NRVLKGEIPW SLELRPEAKN FKTFFVHTPN RTYYLMDPSG 540

NADRWCKKIQ EVWRKIYQRH QNPGV 565

Nucleotide Sequence
(FASTA)

ATGGCAAGAG CGACAAGTCA GCTGTATGAT GTTGTGCCCA TTCAGCCCAA CGTTGTCATC 60

TGTTCCTGCT CACATCCATC AATGGTAAGA AACCACCCTG ACTCCTGCTC GCCACTTGCT 120

ATCCCAGGCG CAAGCAGCCG TCACTGCTCC GGTATGGAAG GCCCAGCTGC AGAGGCTTGT 180

GCTGTAGGAG CGCCTGCAAA CAGCCAGAGC TCAGAGGCCT GCAAGCAGCC GGCCATCCAG 240

CCGGCTCAGC CACGCAAGAA GAAGCCAGAG GACTTCAAGT TTGGCAAAAT ACTGGGAGAG 300

GGCTCCTTCT CAACGGTTGT CCTTGCAAGA GAGCATGCCA CAGGCAAAGA ATTTGCAATT 360

AAGATTTTAG AGAAACGCCA CATTATGAAG GAGAATAAAG TCCAGTACGT GAAAAGAGAA 420

AGGGATTTGA TGTCAAGCCT TGATCACCCA TTCTTCGTCA AGCTCTACTT CACATTTCAA 480

GATGATGAGA AGTTGTATTT TGGGCTCAGT TATGCTAAAA ATGGCGAACT CCTGAAATAC 540

ATACGCAAAA TTGGTTCCTT TGATGAGACC TGCACTCGGT TCTACTCGGC TGAAATAGTT 600

TGTGCATTAG AGTACTTGCA TATTAAGGGG ATAATACACA GAGACCTGAA ACCAGAAAAT 660

ATTCTTCTGA GTGAAGACAT GCACATCCAA ATAACAGATT TTGGAACAGC AAAACAGTTA 720

TCATCAGACA GTAAACAAGC CAGAGCAAAC TCTTTTGTTG GAACAGCACA GTACGTTTCC 780

CCCGAGCTGC TAACAGAGAA GTCGGCCTGC AAAAGCTCTG ACCTGTGGGC TTTGGGGTGT 840

ATTATCTATC AGCTGGTGGC TGGTCTACCT CCATTCAGAG CTGGAAACGA ATACCTTATA 900

TTCCAGAAGA TAATAAAGCT GGAGTATGAA TTTCCTGAGA AATTCTTTCC CAAAGCCAAG 960

GATCTTGTTG AACAGCTTTT GTCATTGGAT CCATCCAAGC GAATTGGATG TGAAGAGATG 1020

GGTGGGTATG AGCCACTGAA GCAGCACCCC TTCTTTGATA CCATTTCCTG GTGTGACCTG 1080

CACCTACAAA CGCCCCCAAA GCTTACACCT TACCTCCCAG CTATGTCTGA AGATGATGAG 1140

GACTGCTATG GAAATTACGA TGACCTCCTG AGCCAGTTCA GCAACATGCA GGTGGCCCAG 1200

TCCAGCTCAT CGCAGTCGCT GTCGCCACAC GACTCAACTC CCCCACAGAG GTCAAGCAGC 1260

AACATTGAAC AGTACATCCA CGACCTGGAC AGCAACTCCT TTGAGCTCGA TCTACAGTTC 1320

ACTGAAGAAG AAAAGAGGTT GTTGCTTGAC AAACAGACCA TTGGGAACCC TTGGCATCAG 1380

TTTGTGGAGA ATAACCTGAT CCTGAAAATG GGCCCAGTGG ATAAACGCAA AGGTCTTTTT 1440

GCACGTCGGC GGCAGCTCCT TCTCACGGAA GGACCACACC TGTACTACGT GGATCCTGTC 1500

AACAGGGTTC TGAAAGGGGA GATTCCTTGG TCCTTAGAGT TACGCCCCGA GGCCAAGAAC 1560

TTCAAAACCT TCTTCGTTCA CACGCCTAAT CGGACATACT ATTTGATGGA CCCCAGTGGA 1620

AATGCAGACA GGTGGTGCAA GAAGATCCAG GAAGTGTGGA GAAAGATTTA TCAAAGACAC 1680

CAAAACCCTG GCGTGTAG 1698

Domain Profile

S: 1     fkfekelgeGsystvvlarekeskkeyaikvlekryiikekkvkyvtrekevlaklnehp  60

         fkf+k+lgeGs+stvvlare ++ ke+aik+lekr+i+ke+kv+yv+re++ ++ l +hp

Q: 92    FKFGKILGEGSFSTVVLAREHATGKEFAIKILEKRHIMKENKVQYVKRERDLMSSL-DHP  150

         89******************************************************.9**

S: 61    givkLyatfqDeeslyfvleyakkGdllellkkvgsfdeactryyaaellsaleflhkkg  120

         ++vkLy+tfqD+e+lyf l+yak+G+ll++++k+gsfde+ctr+y+ae++ ale+lh kg

Q: 151   FFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYSAEIVCALEYLHIKG  210

         ************************************************************

S: 121   iihrDlkpeniLldkdgkilitDfGsakvlepklkedskkeeeesarsksfvGtaeyvsP  180

         iihrDlkpeniLl +d++i+itDfG+ak l++++k+         ar++sfvGta+yvsP

Q: 211   IIHRDLKPENILLSEDMHIQITDFGTAKQLSSDSKQ---------ARANSFVGTAQYVSP  261

         ******************************777766.........9**************

S: 181   elLtdsevskssDlWalgcilyqllaGkpPfraeneylifkkilkleyafpegfpekakd  240

         elLt+++++kssDlWalgci+yql+aG+pPfra neylif+ki+kley+fpe+f++kakd

Q: 262   ELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYEFPEKFFPKAKD  321

         ************************************************************

S: 241   lveklLvkdakerltlee......ikahkff  265

         lve+lL  d+++r+++ee      +k+h+ff

Q: 322   LVEQLLSLDPSKRIGCEEmggyepLKQHPFF  352

         ******************************9

Domain Sequence
(FASTA)

FKFGKILGEG SFSTVVLARE HATGKEFAIK ILEKRHIMKE NKVQYVKRER DLMSSLDHPF 60

FVKLYFTFQD DEKLYFGLSY AKNGELLKYI RKIGSFDETC TRFYSAEIVC ALEYLHIKGI 120

IHRDLKPENI LLSEDMHIQI TDFGTAKQLS SDSKQARANS FVGTAQYVSP ELLTEKSACK 180

SSDLWALGCI IYQLVAGLPP FRAGNEYLIF QKIIKLEYEF PEKFFPKAKD LVEQLLSLDP 240

SKRIGCEEMG GYEPLKQHPF F 261

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR011993	; PH_like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013