EKS-ORL-00025

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORL-00025

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/PHK	490.6	1.4E-147	24	291	268

Status

Unreviewed

Ensembl Protein

ENSORLP00000009764

UniProt Accession

H2LUI7;

Protein Name

Protein Synonyms/Alias

Gene Name

PHKG2

Gene Synonyms/Alias

PHKG2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSORLG00000007794	ENSORLP00000009764	ENSORLT00000009765

Organism

Oryzias latipes

Functional Description

Protein Length

390

Protein Sequence
(FASTA)

MTKDIVVGDE LPDWVGAKEF YQKYDPKEVI GRGVSSVVRR CVHRHTGQEL AVKIIEITAE 60

KMTAQQLEEV KSSTLKEIHL LNMVKGHPSI ITLIDSYEST TFIFLVFDLM RRGELFDYLT 120

EKVTLSEKET RSIMRALLEA VQYLHSLNIV HRDLKPENIL LDDHGHIKLS DFGFSVQLEP 180

GKNLRELCGT PGYLAPEILK CSMDEMHPGY GKEVDLWACG VILFTLLAGS PPFWHRKQML 240

MLRLIMEGRY QFSSPEWDDR SDTVKDLISR LLVVDSAARL TAEQALAHPF FRQYQKEDVR 300

LFSPRKTFRV LIVSVLACIR MYSRYRRVRP LTREVLARDP YSIRGVRKLI DGCAFRIYGH 360

WVKKGEQQNR AALFQNTAKI MLLGLEDFET 390

Nucleotide Sequence
(FASTA)

ATGACCAAGG ACATCGTTGT TGGAGACGAG CTGCCAGACT GGGTGGGAGC GAAGGAATTT 60

TACCAGAAAT ATGACCCGAA GGAGGTTATT GGCAGGGGGG TGAGCAGTGT GGTCCGCCGG 120

TGTGTGCACA GGCACACGGG GCAGGAGCTG GCCGTGAAAA TCATAGAGAT CACCGCCGAG 180

AAGATGACAG CCCAGCAGCT GGAGGAGGTG AAAAGCTCCA CCCTGAAGGA GATCCACCTT 240

CTCAACATGG TGAAGGGACA CCCCTCCATC ATCACTCTCA TTGATTCCTA TGAGTCCACA 300

ACATTCATAT TTCTAGTGTT TGACCTCATG AGGCGAGGAG AGCTGTTTGA CTACCTCACA 360

GAAAAGGTAA CACTGAGTGA GAAGGAGACA AGGAGTATAA TGCGCGCTCT GCTGGAGGCT 420

GTGCAGTACC TGCATTCGCT GAACATCGTG CACCGGGATT TGAAACCTGA AAACATTCTT 480

CTAGATGATC ATGGGCACAT CAAACTCTCT GACTTTGGTT TCTCAGTGCA GCTAGAACCC 540

GGGAAGAATC TCAGAGAACT CTGTGGAACG CCTGGTTACT TGGCCCCAGA AATTCTGAAA 600

TGCTCCATGG ATGAAATGCA TCCAGGCTAT GGCAAAGAGG TTGATCTATG GGCTTGTGGA 660

GTCATCCTCT TCACGCTCTT AGCTGGCTCA CCGCCGTTTT GGCACCGCAA ACAGATGCTG 720

ATGCTGCGGC TGATCATGGA GGGTCGGTAT CAGTTCAGTT CTCCAGAGTG GGATGACCGC 780

TCGGACACTG TGAAAGATCT GATATCAAGG TTGTTGGTGG TGGACTCAGC CGCCCGGCTC 840

ACTGCAGAGC AAGCTTTAGC ACACCCCTTC TTCAGACAGT ACCAGAAAGA GGATGTGCGC 900

CTCTTCAGCC CCAGAAAGAC ATTTCGGGTG TTGATAGTGA GCGTGCTCGC CTGCATCAGA 960

ATGTACAGCC GTTACCGTAG GGTGCGGCCA CTGACCCGCG AGGTGCTGGC CAGAGATCCA 1020

TACTCCATCC GCGGTGTCCG CAAGCTTATC GACGGCTGCG CCTTCCGCAT CTACGGCCAC 1080

TGGGTGAAGA AAGGGGAGCA GCAGAACAGA GCAGCTCTCT TTCAGAACAC GGCGAAGATC 1140

ATGCTCCTGG GGCTGGAGGA CTTTGAAACA TAA 1173

Domain Profile

S: 1     yepkeilGrGvssvvrrciekatgqefavkiidvsaeklseeevkelreatlkeveilrq  60

         y+pke++GrGvssvvrrc++++tgqe avkii+++aek++ ++++e++ +tlke+++l+

Q: 24    YDPKEVIGRGVSSVVRRCVHRHTGQELAVKIIEITAEKMTAQQLEEVKSSTLKEIHLLNM  83

         9***********************************************************

S: 61    vsGhpsiiklkdvyesssflflvfdlmkkGelfdyltekvtlseketrkimralleavey  120

         v Ghpsii+l+d+yes++f+flvfdlm++Gelfdyltekvtlseketr+imralleav+y

Q: 84    VKGHPSIITLIDSYESTTFIFLVFDLMRRGELFDYLTEKVTLSEKETRSIMRALLEAVQY  143

         ************************************************************

S: 121   lhaknivhrdlkpenillddneniklsdfGfstqleeGeklrelcGtpgylapeilkcsm  180

         lh+ nivhrdlkpenilldd+ +iklsdfGfs+qle+G++lrelcGtpgylapeilkcsm

Q: 144   LHSLNIVHRDLKPENILLDDHGHIKLSDFGFSVQLEPGKNLRELCGTPGYLAPEILKCSM  203

         ************************************************************

S: 181   deeapGyskevdlwalGvilytllaGsppfwhrkqllmlrlimeGkyqftspewddisee  240

         de +pGy+kevdlwa+Gvil+tllaGsppfwhrkq+lmlrlimeG+yqf+spewdd+s++

Q: 204   DEMHPGYGKEVDLWACGVILFTLLAGSPPFWHRKQMLMLRLIMEGRYQFSSPEWDDRSDT  263

         ************************************************************

S: 241   vkdliskllvvdpekrltaeealahpff  268

         vkdlis+llvvd+ +rltae+alahpff

Q: 264   VKDLISRLLVVDSAARLTAEQALAHPFF  291

         ***************************8

Domain Sequence
(FASTA)

YDPKEVIGRG VSSVVRRCVH RHTGQELAVK IIEITAEKMT AQQLEEVKSS TLKEIHLLNM 60

VKGHPSIITL IDSYESTTFI FLVFDLMRRG ELFDYLTEKV TLSEKETRSI MRALLEAVQY 120

LHSLNIVHRD LKPENILLDD HGHIKLSDFG FSVQLEPGKN LRELCGTPGY LAPEILKCSM 180

DEMHPGYGKE VDLWACGVIL FTLLAGSPPF WHRKQMLMLR LIMEGRYQFS SPEWDDRSDT 240

VKDLISRLLV VDSAARLTAE QALAHPFF 268

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005964	; C:phosphorylase kinase complex
GO:0005524	; F:ATP binding
GO:0004689	; F:phosphorylase kinase activity
GO:0005978	; P:glycogen biosynthetic process

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR002291	; Phosph_kin_gamma.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR01049

; PHOSPHBKNASE.

Created Date

20-Feb-2013