EPS-ORL-00043

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-ORL-00043

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	168.5	2.8E-49	783	1029	247

Status

Unreviewed

Ensembl Protein

ENSORLP00000009956

UniProt Accession

H2LV25;

Protein Name

Protein Synonyms/Alias

Gene Name

PHLPP2

Gene Synonyms/Alias

PHLPP2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSORLG00000007937	ENSORLP00000009956	ENSORLT00000009957
ENSORLG00000007937	ENSORLP00000009953	ENSORLT00000009954

Organism

Oryzias latipes

Functional Description

Protein Length

1158

Protein Sequence
(FASTA)

MKRNGSRSCV TRKSRFGSRE RDWLKGDTQR GCVCLYRGTA EPPPPSSGPQ TSSNPQTDLQ 60

LVLCSTSTTV DELCAQRDGQ ELYIQLHGDL VRRMDSSEQP LQMVYDYLTS MGYADLTRVQ 120

HEAANSDLSC LIRFYSERPV NADQQERTLL KGVFSVRKGK TQLHKWAERQ VILCGTCLIV 180

ASVKDSLTGK MHILPLVGGK VEEVKRRQHC LMFSSAGSQA QTYFVNFDSL AEYQRWHRQA 240

SKVVSQTVSV VDLSCYSLET VPEYLFYCQD ITHLNLRHNF MNLQGSGGLL NLPRFSQLKS 300

LNLSHNRLGV FPECVCEILT LTELNLSCNK IHTIPEQISN LQSLQTLSLD GNHLQSLPKE 360

LGDLSQLNSL GLSFNDFSHI PAVLERLSTV DKLAMAGNRV ESLDLCTLIR MSHLRNVDLR 420

LNSLRWVKSE ALTGMSQVTL LDLRDNLLDS ADLSSMCNLE TLHCQRNQLG TLTLSGFTLR 480

TLHASSNRLT TVNLYPVPNQ LTHMDLSQNL LEYLPDWICD CRKIEVLDIT HNLLSELPSR 540

LFNSLSLRRL LTGNNRLQRL PDLLDHVPLE ALDLQHNRLK ELPESLFCKA LNLKFLNASA 600

NALESIPPSS QSEENLSTLQ ELYLSGNNLN ENCAALLVGH RNLHVLHMAY NQLLSFPASK 660

LSKLELLEEL NLSGNKLKSI PSTVSSCKRL HTLIAHSNHL TVFPEILSLP EIKLVDLSCN 720

ELTEIQLAES LPATLQELDL TGNSNLILEH KTLNLFSHIT TLKLDQKCVA TLGDSLSSSC 780

PWSHGYSEMT GQRNKLCVSV LAVDRFGDGV EACYGIFDGD RNEEVPRLLQ CTMGDVLCEE 840

LQHSSIDSVY MCNTFLTSHR KLGMAGQKLG ASALLCYIHH EATDSGGYLG LTVANVGTCQ 900

AVLCRNGRPV QLSKVYSLES CHEEMERVKL HKAIITEDNK VSGVTCCSRL LGCSYLSPWV 960

LPKPWVHTES LCPQDEFLIL GNRALFERVS YQEAVCTVQA VRDPQTAAKK LCSLAQSYGC 1020

KDNIGAVVVS LQIGEDSCTC EAPVSTTVTP TPNDQASLSS SSGVVTEFSS ETSASEVGSE 1080

AGSTASDENP SSVPGSRPER RCSLHPSSAP GIFQRQPTST MFSSKQSDNG LDSDDEGPLE 1140

GVMSNGSKLE VEVDIHCC 1158

Nucleotide Sequence
(FASTA)

ATGAAGCGGA ACGGGAGCCG GAGCTGTGTG ACTAGAAAAA GTCGATTTGG GTCTCGGGAG 60

AGGGACTGGC TGAAGGGGGA CACCCAGCGG GGCTGTGTGT GCCTTTACAG GGGCACTGCG 120

GAGCCCCCAC CACCTTCCTC TGGCCCACAA ACCTCCTCCA ACCCCCAGAC GGACCTGCAG 180

TTGGTGCTCT GCTCCACTAG TACCACAGTG GATGAGCTCT GCGCTCAGAG GGATGGACAG 240

GAGCTCTACA TTCAGCTCCA TGGAGATCTT GTCAGGAGAA TGGACTCCTC TGAGCAACCC 300

CTCCAGATGG TTTATGACTA CTTGACATCA ATGGGGTACG CTGACCTGAC GCGGGTGCAG 360

CATGAAGCTG CTAACTCTGA CCTCAGCTGT TTGATCCGTT TCTACAGTGA ACGTCCAGTG 420

AATGCGGACC AGCAGGAGCG AACCTTGCTG AAGGGTGTGT TCAGCGTGAG GAAAGGAAAA 480

ACACAGCTGC ACAAGTGGGC AGAGCGGCAG GTTATCCTCT GTGGCACCTG TTTGATCGTG 540

GCGTCTGTGA AAGACAGTCT GACTGGGAAG ATGCACATCC TGCCTCTGGT GGGGGGAAAG 600

GTTGAGGAGG TAAAGCGGAG GCAGCACTGT CTGATGTTCA GCTCAGCCGG CTCACAGGCC 660

CAGACTTACT TTGTCAACTT CGACTCACTC GCAGAGTACC AGCGATGGCA TCGGCAGGCA 720

TCAAAAGTAG TGTCTCAGAC AGTAAGTGTG GTGGACCTGT CCTGCTACAG CCTGGAAACA 780

GTGCCTGAAT ACCTGTTTTA CTGTCAAGAC ATCACCCACC TTAACCTGCG GCACAACTTC 840

ATGAACCTAC AGGGGTCTGG AGGCCTGCTC AACCTCCCCA GGTTTTCCCA GCTAAAAAGC 900

CTGAACTTGT CTCACAATCG TCTGGGTGTG TTCCCAGAGT GTGTGTGTGA AATCCTCACC 960

TTAACTGAAC TCAACCTGTC CTGTAATAAA ATCCACACCA TCCCGGAGCA GATCAGCAAC 1020

CTTCAGAGCC TGCAGACATT ATCTTTGGAT GGAAACCATC TCCAATCTCT GCCCAAAGAA 1080

CTGGGTGACC TGTCTCAACT CAACAGCCTG GGGCTCTCCT TCAATGATTT CTCTCACATT 1140

CCAGCTGTGC TTGAGAGATT AAGTACAGTG GACAAGCTGG CCATGGCTGG GAACAGAGTG 1200

GAGAGTCTGG ATTTATGTAC ACTGATTAGA ATGAGCCATC TAAGAAACGT CGACCTCCGG 1260

TTGAATAGTC TTAGGTGGGT TAAAAGCGAA GCCCTAACAG GAATGAGTCA GGTGACCCTG 1320

CTGGACCTAC GGGATAACCT CCTGGATTCG GCAGACCTGA GCTCCATGTG CAACCTGGAA 1380

ACTCTGCACT GCCAAAGGAA CCAGCTGGGA ACGCTCACAC TCAGCGGCTT CACACTGCGC 1440

ACGCTTCACG CCAGCAGCAA CCGCCTTACA ACAGTCAACC TATATCCAGT CCCTAATCAG 1500

CTGACACACA TGGACCTCTC ACAGAACCTC TTGGAATACC TTCCAGACTG GATATGTGAC 1560

TGCAGAAAAA TTGAGGTGCT GGACATAACG CACAACCTCC TGTCTGAACT TCCTTCCAGA 1620

CTGTTTAACA GCTTGAGCTT GAGGAGGCTG CTAACGGGCA ACAATCGTTT GCAGAGACTG 1680

CCTGACCTAC TTGACCATGT TCCTTTGGAA GCCCTAGACC TCCAGCATAA CAGGCTAAAA 1740

GAGCTTCCTG AGAGTCTTTT CTGCAAGGCC TTAAATCTAA AATTTCTAAA CGCATCAGCC 1800

AATGCCCTGG AGAGTATTCC TCCTAGCAGC CAATCAGAGG AGAACCTCAG CACACTTCAG 1860

GAACTCTACC TGTCAGGTAA CAACCTGAAC GAGAACTGTG CCGCCCTGCT GGTTGGACAC 1920

CGTAACCTTC ATGTCCTTCA TATGGCCTAC AACCAACTTC TCTCATTTCC TGCCAGCAAG 1980

CTGAGTAAGC TGGAACTGTT GGAGGAGCTA AATCTAAGTG GCAACAAACT AAAGAGTATC 2040

CCTTCCACCG TGTCTAGTTG TAAGAGACTG CACACCCTCA TAGCACACTC GAATCATTTA 2100

ACTGTCTTCC CAGAGATCCT CAGTCTTCCT GAGATCAAGC TTGTAGATCT AAGCTGCAAT 2160

GAGCTGACTG AGATCCAGCT CGCTGAATCC CTGCCTGCAA CCCTGCAAGA GCTGGATCTG 2220

ACGGGAAACA GCAACCTCAT TTTAGAGCAC AAAACCCTCA ACCTCTTCAG TCACATCACT 2280

ACCTTAAAAT TAGACCAGAA ATGCGTTGCG ACACTCGGAG ATTCGCTCAG CTCCTCCTGT 2340

CCGTGGAGCC ATGGTTACTC TGAAATGACC GGTCAAAGGA ACAAGTTATG TGTGTCTGTG 2400

TTGGCTGTCG ATCGCTTTGG AGACGGCGTG GAAGCATGCT ATGGTATCTT CGACGGTGAT 2460

CGCAATGAAG AAGTGCCTCG GCTGTTGCAG TGCACTATGG GAGATGTACT GTGTGAAGAA 2520

CTGCAGCACT CCAGCATTGA CAGTGTGTAC ATGTGTAACA CCTTCCTCAC CTCACACAGG 2580

AAACTTGGTA TGGCTGGGCA GAAACTTGGT GCTTCTGCAT TGCTGTGCTA CATTCATCAT 2640

GAAGCCACAG ACTCTGGAGG CTACCTTGGC CTTACTGTGG CCAACGTTGG CACCTGCCAG 2700

GCTGTTCTGT GCCGCAACGG ACGACCTGTT CAGCTCTCAA AGGTCTACAG CTTAGAGAGC 2760

TGCCACGAAG AGATGGAAAG GGTGAAACTC CACAAGGCCA TAATAACAGA GGACAACAAA 2820

GTGAGTGGAG TCACATGCTG CTCTCGTCTG TTGGGCTGCT CCTACCTGTC TCCTTGGGTG 2880

CTTCCGAAGC CGTGGGTGCA CACCGAGTCC CTCTGTCCGC AGGATGAGTT TTTGATCCTG 2940

GGGAATCGGG CCTTGTTTGA ACGAGTGTCC TACCAGGAAG CCGTGTGCAC TGTGCAGGCT 3000

GTGCGAGATC CACAGACTGC TGCCAAAAAG CTGTGCTCAC TTGCCCAGAG TTATGGTTGC 3060

AAGGACAACA TTGGAGCCGT GGTGGTGTCC CTTCAGATAG GGGAGGATAG CTGCACTTGT 3120

GAGGCTCCGG TGTCAACCAC TGTGACTCCA ACCCCCAATG ATCAAGCCAG CCTCTCCTCC 3180

AGCAGTGGTG TTGTCACTGA GTTTAGCAGT GAAACATCAG CCTCAGAGGT GGGGAGTGAG 3240

GCGGGGTCCA CCGCCTCAGA TGAAAACCCT TCCTCTGTCC CAGGATCCCG TCCAGAAAGG 3300

CGCTGCAGCC TGCACCCCTC TTCTGCACCA GGAATATTCC AGCGGCAACC AACTTCTACT 3360

ATGTTTTCAA GTAAGCAATC TGACAATGGC TTGGACAGTG ATGATGAAGG TCCACTTGAG 3420

GGCGTCATGT CCAATGGTAG CAAGTTAGAA GTGGAGGTGG ATATTCACTG CTGT 3474

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g++++ g+rn+++ +v ++++f++  e+      +g++DG++++ev + +++++ ++l

Q: 783   SHGYSEMTGQRNKLCVSVLAVDRFGDGVEA-----CYGIFDGDRNEEVPRLLQCTMGDVL  837

         689***********************9875.....8************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

          eel+    ++   + ++ ++Fl+ +++l       ++ +k G++a++++i ++

Q: 838   CEELQ----HSSIDSVYMCNTFLTSHRKL------GMAGQKLGASALLCYIHHEatdsgg  887

         ***99....66666778************......89***************999999**

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsre.dEleRieeaggsvilkdgaRvlGvL  172

            l+vanvG ++avLcrng +v+ls+ ++ ++  +E+eR++ +++ +++++  +v Gv+

Q: 888   ylGLTVANVGTCQAVLCRNGRPVQLSKVYSLESChEEMERVKLHKAIITEDN--KVSGVT  945

         ******************************976449*********9999998..******

S: 173   avsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekk  232

         ++sR lG+ yl+p+v p+P v+   l ++defliL+   l++ vs +eav  v+ v +

Q: 946   CCSRLLGCSYLSPWVLPKPWVHTESLCPQDEFLILGNRALFERVSYQEAVCTVQAVRD--  1003

         **********************************************************..

S: 233   eaeqeaakkLvklalargskdnvsaivv  260

           +q+aakkL+ la+++g+kdn+ a+vv

Q: 1004  --PQTAAKKLCSLAQSYGCKDNIGAVVV  1029

         ..***********************997

Domain Sequence
(FASTA)

SHGYSEMTGQ RNKLCVSVLA VDRFGDGVEA CYGIFDGDRN EEVPRLLQCT MGDVLCEELQ 60

HSSIDSVYMC NTFLTSHRKL GMAGQKLGAS ALLCYIHHEA TDSGGYLGLT VANVGTCQAV 120

LCRNGRPVQL SKVYSLESCH EEMERVKLHK AIITEDNKVS GVTCCSRLLG CSYLSPWVLP 180

KPWVHTESLC PQDEFLILGN RALFERVSYQ EAVCTVQAVR DPQTAAKKLC SLAQSYGCKD 240

NIGAVVV 247

Keyword

Complete proteome; Leucine-rich repeat; Reference proteome; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>