EKS-ORL-00346

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORL-00346

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/IRE	410.4	3.9E-123	564	824	261

Status

Unreviewed

Ensembl Protein

ENSORLP00000011199

UniProt Accession

H2LYI2;

Protein Name

Protein Synonyms/Alias

Gene Name

ERN2

Gene Synonyms/Alias

ERN2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSORLG00000008924	ENSORLP00000011199	ENSORLT00000011200

Organism

Oryzias latipes

Functional Description

Protein Length

953

Protein Sequence
(FASTA)

PSVYSVLLLL LGVHTPPPSF SAGARSVTLP ESLLFISTLD GSLHAVSKQT GDIKWTLRED 60

PIIQVPVYLT EPDFLPDPND GSLYVLGGKH KEGLMKLPFT IPELVQSAPC RSSDGILYTG 120

SGKKQDVWFV VDPETGEKQT SLTTSSSESI CPNSPLLYIG RTEYVITMFD TKTQELRWNA 180

TYNDYSAPPY DEKLDYKMAH LVSSGDGLVV TVDRESGDVL WSQNYGSPVI GVYLYSGDSL 240

RHAPHLSLAI ETLRFLTFSA KDQAEAHSSL KWSYQFVKEQ ATAQAQLVPT LYVGKLDSHF 300

YASTSLVHHG VSLLPRGLIL ARIEGPVTSG VTVSGRGECE ITPSTDVRYP PGSTASKKNH 360

WLLIAAGHHE LPPVAHTTIL RDFPVSLQHS TEKVIPPRST ASSFQKVSGI HGNPESNKEG 420

ADGRKTVQTP RPAAALPISL TQDHLTLAVL TLLLGGWLVF VLTCLLRPTQ QLTVQRQREE 480

AFETHPQVIH NNNQTNASVS EDVTQSTDTN VTKDPDSPPS STDSPPSLNS HSSNIPDSEE 540

VSAAAHKTTE EGFSEEVQVG KVSFFPSEVL GHGSAGTFVF KGKFDGRHVA VKRILPECFE 600

VAEREVQLLR ESDTHPNVIR YFCTERDRLF TYIAIELCTA TLQQYVEDPA SFSNLSPITV 660

LEQTMCGLSH LHSLNIVHRD LKPRNILLSG PGALGRVRAL ISDFGLCKKI PDGRSSFSMR 720

SGIPGTEGWI APEVLRDTPG NKPTAAVDVF SAGCVFYYVV SRGQHPFGDA LRRQINILSG 780

EYSLSHFKEE SNDDIIARDL IEQMIGANAE TRPSTECVLK HPFFWSREKQ LLFFQDVSDR 840

IEKEPADSPI VVRLETAGRV VVRTNWRMHI SVPLQTDLRR FRTYKGNSVR DLLRAMRNKK 900

HHYHELPPEV QETLGELPEG FVSYFTSRFP RLLMHTHAAL HICAQERLFH PYY 953

Nucleotide Sequence
(FASTA)

CCCTCAGTGT ATTCGGTATT ATTACTACTT TTGGGCGTAC ATACGCCCCC GCCTTCATTT 60

AGTGCAGGGG CCAGATCAGT CACACTCCCA GAGTCCCTTC TGTTCATCTC CACCTTGGAT 120

GGCAGCCTGC ATGCCGTCTC CAAACAGACA GGAGACATCA AGTGGACCCT AAGAGAAGAC 180

CCCATTATTC AAGTTCCTGT TTACCTCACA GAGCCCGATT TCCTCCCAGA TCCAAATGAC 240

GGCAGTTTAT ATGTACTCGG TGGAAAGCAC AAGGAGGGTC TGATGAAACT GCCATTCACC 300

ATCCCAGAGC TGGTTCAGTC AGCTCCCTGC AGAAGCTCTG ATGGCATACT GTACACAGGT 360

TCAGGGAAAA AGCAGGATGT GTGGTTTGTG GTGGATCCTG AAACAGGCGA AAAACAAACA 420

AGCCTAACCA CCTCCTCCTC CGAATCCATC TGTCCCAACA GCCCTCTGCT CTACATCGGA 480

CGCACAGAGT ATGTGATTAC CATGTTTGAC ACGAAGACGC AGGAACTGAG ATGGAATGCA 540

ACGTACAACG ATTACTCTGC CCCTCCTTAT GACGAGAAGC TAGACTACAA GATGGCCCAT 600

CTGGTGTCAA GCGGTGACGG ACTTGTTGTG ACTGTGGACA GAGAGTCAGG GGATGTCCTG 660

TGGAGTCAGA ACTACGGCTC CCCGGTCATC GGGGTGTACC TGTACTCTGG GGACTCTCTG 720

AGACACGCGC CTCACCTGTC CCTTGCCATA GAAACGCTCC GGTTCCTCAC CTTCTCCGCC 780

AAGGATCAGG CAGAAGCACA CTCTTCCTTG AAGTGGAGCT ATCAGTTTGT GAAAGAGCAA 840

GCCACTGCGC AGGCTCAGCT TGTACCCACT CTCTATGTCG GAAAGCTGGA CTCTCACTTC 900

TATGCCTCCA CTTCTCTCGT CCACCATGGT GTCTCATTAT TGCCGCGAGG ATTGATCCTG 960

GCACGGATCG AGGGTCCAGT GACGTCTGGA GTGACGGTTA GCGGGAGAGG GGAGTGTGAA 1020

ATCACACCGT CTACTGATGT GCGTTATCCA CCAGGAAGCA CAGCCAGCAA GAAAAACCAC 1080

TGGCTGCTCA TAGCTGCAGG GCACCATGAG CTCCCTCCTG TAGCCCACAC CACCATCCTG 1140

AGGGATTTTC CCGTCTCTCT GCAGCACTCC ACTGAGAAAG TTATCCCACC TCGATCTACG 1200

GCTTCCTCTT TCCAGAAAGT GTCTGGAATC CACGGCAACC CGGAGTCTAA CAAAGAAGGA 1260

GCTGACGGCA GGAAAACGGT ACAGACTCCA AGGCCAGCCG CTGCGCTACC CATCAGCCTG 1320

ACGCAGGACC ACCTGACCCT GGCTGTCCTC ACTCTGCTGC TTGGAGGATG GCTCGTCTTT 1380

GTGCTCACGT GTCTCCTCCG TCCCACCCAG CAGCTGACAG TTCAGAGGCA GCGAGAAGAA 1440

GCGTTTGAGA CTCACCCCCA GGTCATACAC AACAATAATC AGACCAACGC CTCCGTTTCT 1500

GAAGACGTGA CCCAGTCTAC TGACACAAAT GTCACAAAGG ACCCAGACTC TCCACCTTCA 1560

TCCACCGACT CTCCACCCAG CCTCAACAGT CACAGCAGCA ACATCCCCGA CTCAGAGGAA 1620

GTTAGTGCTG CTGCTCATAA AACCACAGAA GAAGGGTTCA GTGAGGAAGT GCAGGTGGGA 1680

AAAGTTTCCT TTTTCCCCTC GGAGGTGCTT GGACATGGAT CTGCAGGAAC ATTTGTGTTT 1740

AAGGGTAAAT TTGATGGACG GCATGTGGCG GTGAAGCGAA TCCTGCCAGA GTGTTTTGAG 1800

GTGGCAGAGC GGGAGGTGCA GCTCCTCCGG GAGTCCGACA CGCATCCAAA TGTCATCCGA 1860

TATTTCTGCA CAGAGAGGGA CCGCCTTTTC ACTTACATCG CCATCGAACT ATGCACTGCA 1920

ACGCTGCAAC AGTATGTGGA AGATCCCGCT TCTTTCTCGA ATCTGAGTCC AATAACTGTG 1980

CTGGAGCAGA CCATGTGTGG CCTCTCCCAC CTCCATTCAC TCAACATAGT CCATCGTGAC 2040

CTGAAGCCGA GGAACATTCT CCTCTCTGGG CCTGGAGCTC TGGGAAGAGT CCGAGCTCTC 2100

ATCTCAGACT TCGGACTCTG TAAAAAGATC CCCGACGGAC GAAGCAGCTT CTCTATGCGG 2160

TCTGGAATAC CAGGAACTGA AGGGTGGATA GCCCCCGAAG TGCTCCGAGA CACACCAGGA 2220

AACAAACCGA CGGCAGCAGT GGACGTGTTC TCGGCAGGCT GTGTCTTCTA CTATGTGGTC 2280

AGCAGAGGGC AGCACCCCTT TGGAGATGCG TTAAGAAGAC AAATTAACAT CCTGTCTGGA 2340

GAATATTCCC TCTCACACTT TAAAGAGGAA TCAAATGATG ACATCATAGC GCGGGATCTG 2400

ATTGAGCAGA TGATTGGTGC CAACGCAGAA ACCCGGCCCT CCACCGAGTG TGTGCTCAAA 2460

CACCCTTTCT TCTGGAGTCG GGAGAAACAG CTGCTCTTTT TCCAGGACGT GAGTGATCGG 2520

ATAGAGAAGG AGCCAGCAGA CAGCCCCATT GTGGTCAGAC TAGAGACGGC AGGACGAGTG 2580

GTGGTCCGGA CGAACTGGAG AATGCACATC TCTGTCCCTC TGCAGACAGA CTTGAGGCGG 2640

TTCAGGACAT ATAAAGGAAA CTCCGTTAGA GATCTGCTTC GAGCCATGAG GAATAAGAAG 2700

CATCACTATC ATGAGTTACC CCCAGAGGTG CAGGAGACTC TTGGCGAGCT TCCCGAGGGC 2760

TTCGTCAGCT ACTTCACCTC ACGGTTTCCA CGGTTACTGA TGCACACACA TGCTGCTCTC 2820

CACATCTGTG CTCAGGAGAG GCTGTTTCAT CCATACTAT 2859

Domain Profile

S: 1     fspkdvlGkGaeGtvvfrGsfegrevavkrllsefvdlakrevkllresdehpnviryfc  60

         f p++vlG+G+ Gt+vf+G+f+gr+vavkr+l+e++++a+rev+llresd+hpnviryfc

Q: 564   FFPSEVLGHGSAGTFVFKGKFDGRHVAVKRILPECFEVAEREVQLLRESDTHPNVIRYFC  623

         5789********************************************************

S: 61    tekdrqfryialelcaaslqdyvedkdlelqkelepisllkqiasGlahlhslkivhrdl  120

         te+dr f yia+elc+a+lq+yved+      +l pi++l+q++ Gl+hlhsl+ivhrdl

Q: 624   TERDRLFTYIAIELCTATLQQYVEDPASF--SNLSPITVLEQTMCGLSHLHSLNIVHRDL  681

         ************************98655..79***************************

S: 121   kpqnilislpdakgklrvlisdfGlckkldvGkssfsrrsgvsGteGwiapelleeltke  180

         kp+nil+s p a g++r+lisdfGlckk++ G+ssfs+rsg++GteGwiape+l++++ +

Q: 682   KPRNILLSGPGALGRVRALISDFGLCKKIPDGRSSFSMRSGIPGTEGWIAPEVLRDTPGN  741

         ************************************************************

S: 181   rltsavdifslGcvfyyvlskGkhpfGdslkrqanilsgelsldklkeekdeeviaedli  240

         ++t avd+fs+Gcvfyyv+s+G+hpfGd l+rq nilsge+sl+++kee+++++ia+dli

Q: 742   KPTAAVDVFSAGCVFYYVVSRGQHPFGDALRRQINILSGEYSLSHFKEESNDDIIARDLI  801

         ************************************************************

S: 241   skmidkdplkrpsakkvlkhplf  263

         ++mi  +  +rps+++vlkhp+f

Q: 802   EQMIGANAETRPSTECVLKHPFF  824

         **********************9

Domain Sequence
(FASTA)

FFPSEVLGHG SAGTFVFKGK FDGRHVAVKR ILPECFEVAE REVQLLRESD THPNVIRYFC 60

TERDRLFTYI AIELCTATLQ QYVEDPASFS NLSPITVLEQ TMCGLSHLHS LNIVHRDLKP 120

RNILLSGPGA LGRVRALISD FGLCKKIPDG RSSFSMRSGI PGTEGWIAPE VLRDTPGNKP 180

TAAVDVFSAG CVFYYVVSRG QHPFGDALRR QINILSGEYS LSHFKEESND DIIARDLIEQ 240

MIGANAETRP STECVLKHPF F 261

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mustela putorius furo"; ?>Oreochromis niloticus"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Takifugu rubripes"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0016891	; F:endoribonuclease activity, producing 5'-phosphomonoesters
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006397	; P:mRNA processing

KEGG

InterPros

IPR010513	; KEN_RNase_activator.
IPR011009	; Kinase-like_dom.
IPR018391	; PQQ_beta_propeller_repeat.
IPR000719	; Prot_kinase_cat_dom.
IPR006567	; PUG-dom.
IPR011047	; Quinonprotein_ADH-like.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF06479	; Ribonuc_2-5A; 1.

SMARTs

SM00564	; PQQ; 5.
SM00580	; PUG; 1.

Prosites

PS51392	; KEN; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013