EKS-ORL-00279

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORL-00279

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/MAPKAPK	425.7	7.7E-128	60	321	262

Status

Unreviewed

Ensembl Protein

ENSORLP00000016665

UniProt Accession

H2MDM0;

Protein Name

Protein Synonyms/Alias

Gene Name

MAPKAPK3 (1 of 2)

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSORLG00000013296	ENSORLP00000016665	ENSORLT00000016666

Organism

Oryzias latipes

Functional Description

Protein Length

398

Protein Sequence
(FASTA)

MLQNGNIKEE KLPQPEETGE TKGDSPGPAA DDKDSEPSHF PMPVHTKLEI KRNAVTDDYK 60

ISSQVLGLGI NGKVLECFNK KTGVKCALKI LYDSPKARRE VELHWRVSGG PYIVRILNLY 120

ENMHHGKKCL LIIMECMEGG ELFSRIQARG DQAFTEKEAS GIMKDIGTAI EFLHNINIAH 180

RDVKPENLLY TSKQKNAVLK LTDFGFAKET TLHNPLQTPC YTPYYVAPEV LGPEKYDKSC 240

DMWSLGVIMY ILLCGFPPFY SNTGQAISPG MKRRIRMGQY EFPKPEWSEV SQEAKDLIHQ 300

LLKTDPSERM TITQFMNHPW INQSMMVPST PLHRVLTEDR EMWEDVKEEM TSALATMRVD 360

YDQVKIKDLD TSSNPLLNKR RKKAAAGAKS GSTVCQSQ 398

Nucleotide Sequence
(FASTA)

ATGCTTCAAA ATGGAAATAT TAAGGAGGAA AAGCTGCCGC AACCAGAAGA GACGGGGGAG 60

ACGAAGGGTG ACTCACCCGG TCCCGCGGCG GACGACAAGG ACTCCGAGCC CTCACACTTC 120

CCCATGCCGG TTCACACCAA ACTGGAGATA AAACGCAACG CAGTGACGGA CGATTACAAA 180

ATCTCCAGTC AGGTTCTGGG CCTGGGGATC AATGGGAAAG TCCTGGAGTG CTTCAATAAG 240

AAGACTGGAG TCAAGTGCGC GCTGAAGATT TTGTACGACA GTCCCAAAGC CAGACGAGAA 300

GTTGAGCTTC ACTGGCGGGT TTCTGGGGGG CCGTACATCG TTCGCATTCT GAATCTCTAT 360

GAGAACATGC ATCATGGGAA GAAGTGTCTG CTCATCATCA TGGAGTGCAT GGAGGGAGGA 420

GAGCTGTTCA GCCGGATCCA AGCCAGAGGG GACCAGGCCT TCACTGAAAA AGAGGCATCA 480

GGGATCATGA AGGACATTGG CACAGCCATC GAGTTTCTCC ACAACATCAA CATTGCACAC 540

AGGGATGTCA AGCCAGAGAA CCTGCTGTAC ACCTCCAAAC AGAAAAACGC AGTCCTCAAA 600

CTGACAGACT TTGGCTTCGC CAAGGAGACA ACCCTGCACA ACCCTCTGCA GACGCCCTGT 660

TACACACCCT ACTACGTTGC TCCTGAGGTC TTGGGACCGG AGAAATATGA CAAGTCGTGC 720

GACATGTGGT CTCTGGGTGT CATCATGTAC ATCCTGTTGT GTGGGTTCCC TCCATTTTAC 780

TCCAACACCG GTCAGGCCAT CTCTCCGGGG ATGAAGAGGA GAATCCGGAT GGGCCAGTAT 840

GAATTCCCCA AACCGGAATG GTCTGAGGTG TCACAAGAAG CAAAAGATTT GATCCACCAG 900

TTATTGAAAA CAGACCCCAG TGAGAGGATG ACCATCACAC AGTTTATGAA CCACCCCTGG 960

ATCAATCAGT CCATGATGGT TCCATCCACT CCCCTTCACA GGGTCCTGAC GGAAGACAGA 1020

GAGATGTGGG AGGATGTGAA GGAGGAGATG ACCAGTGCTT TAGCCACCAT GCGCGTGGAC 1080

TACGATCAGG TGAAGATCAA GGATCTCGAC ACGTCCAGCA ACCCTCTGCT CAACAAGAGG 1140

CGCAAGAAGG CCGCCGCGGG AGCCAAGAGT GGCTCAACGG TCTGCCAGAG TCAGTAA 1197

Domain Profile

S: 1     klteevlGeGisgkvlecvkkktgekyalkilkdrkkvrrevelhvqasghknivelidv  60

         k++++vlG Gi+gkvlec++kktg k+alkil+d++k+rrevelh+++sg ++iv+++++

Q: 60    KISSQVLGLGINGKVLECFNKKTGVKCALKILYDSPKARREVELHWRVSGGPYIVRILNL  119

         5789********************************************************

S: 61    fensfedekrlllvlekleGGellsriqer..kaftekeasevvkdiasalkflhsknia  118

         +en+++++k+ll+++e++eGGel+sriq r  +aftekeas ++kdi++a++flh+ nia

Q: 120   YENMHHGKKCLLIIMECMEGGELFSRIQARgdQAFTEKEASGIMKDIGTAIEFLHNINIA  179

         *******************************9****************************

S: 119   hrDlkpenlLyeskeknapvklcDfglaketeeeeelktpcltaeyvaPevleaekeeal  178

         hrD+kpenlLy+sk+kna++kl+Dfg+aket+ ++ l+tpc+t++yvaPevl++ek

Q: 180   HRDVKPENLLYTSKQKNAVLKLTDFGFAKETTLHNPLQTPCYTPYYVAPEVLGPEK----  235

         ********************************************************....

S: 179   lydksCDlWslGvilyillcGypPfyskkgraiskklkeriqegkyefPeeeWsevseea  238

          ydksCD+WslGvi+yillcG+pPfys++g+ais+++k+ri++g+yefP++eWsevs+ea

Q: 236   -YDKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRMGQYEFPKPEWSEVSQEA  294

         .***********************************************************

S: 239   kdlirklLkrdpkerltieevlnhpwv  265

         kdli++lLk+dp+er+ti++++nhpw+

Q: 295   KDLIHQLLKTDPSERMTITQFMNHPWI  321

         **************************8

Domain Sequence
(FASTA)

KISSQVLGLG INGKVLECFN KKTGVKCALK ILYDSPKARR EVELHWRVSG GPYIVRILNL 60

YENMHHGKKC LLIIMECMEG GELFSRIQAR GDQAFTEKEA SGIMKDIGTA IEFLHNINIA 120

HRDVKPENLL YTSKQKNAVL KLTDFGFAKE TTLHNPLQTP CYTPYYVAPE VLGPEKYDKS 180

CDMWSLGVIM YILLCGFPPF YSNTGQAISP GMKRRIRMGQ YEFPKPEWSE VSQEAKDLIH 240

QLLKTDPSER MTITQFMNHP WI 262

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013