EKS-ORL-00560

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORL-00560

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMK1	368.2	2.6E-110	31	285	255

Status

Unreviewed

Ensembl Protein

ENSORLP00000017485

UniProt Accession

H2MFV8;

Protein Name

Protein Synonyms/Alias

Gene Name

CAMK4

Gene Synonyms/Alias

CAMK4;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSORLG00000013945	ENSORLP00000017485	ENSORLT00000017486

Organism

Oryzias latipes

Functional Description

Protein Length

324

Protein Sequence
(FASTA)

ATTMPTSRPG SEPVEFWVDG SRRDGTVEDF YTLGSELGRG ATSIVYRCEE KQTQKPYAVK 60

VLKKTIDKKI VRTEIGVLLR LSHPNIIQLK EIFETDTDIA LVLELVTGGE LFDRIVERGY 120

YSERDAAHVI KQILEAVAYL HENGVVHRDL KPENLLYADL SLDASLKIAD FGLSKIIDDQ 180

VTMKTVCGTP GYCAPEILRG NAYGPEVDMW SVGVILYILL CGFEPFFDPR GDQYMYSRIL 240

NCDYEFVSPW WDEVSLNAKD LVGKLIVLDP HKRLSVREAL QHPWVLGKAA RFSHMDTTQR 300

KLQEFNARRK LKAAMKAVVA TSRM 324

Nucleotide Sequence
(FASTA)

GCAACAACCA TGCCGACGTC CCGTCCGGGT TCGGAGCCGG TGGAGTTCTG GGTGGACGGG 60

TCACGGCGGG ACGGGACGGT GGAGGACTTC TACACTCTGG GATCCGAGCT GGGCAGAGGA 120

GCAACGTCCA TCGTGTATCG CTGTGAGGAG AAGCAGACCC AGAAACCCTA CGCTGTCAAA 180

GTCCTCAAAA AAACGATTGA CAAGAAAATC GTTCGAACAG AAATCGGCGT CTTGTTACGT 240

CTTTCACATC CCAACATTAT CCAGTTAAAG GAGATCTTTG AAACAGATAC TGACATCGCA 300

CTCGTGCTCG AACTGGTGAC AGGAGGAGAG CTTTTTGACC GCATTGTGGA GCGCGGTTAC 360

TACAGCGAGA GAGACGCAGC CCACGTCATC AAGCAGATAC TAGAGGCCGT TGCGTATTTG 420

CATGAAAATG GGGTCGTCCA TCGAGATCTC AAACCGGAGA ACCTGCTTTA TGCCGACCTG 480

TCCCTGGACG CTTCACTAAA GATAGCCGAT TTTGGACTTT CAAAAATTAT TGATGACCAG 540

GTGACCATGA AGACGGTCTG TGGTACTCCA GGTTACTGTG CTCCAGAGAT CCTGCGGGGA 600

AATGCTTACG GCCCTGAGGT GGACATGTGG TCGGTGGGCG TCATCCTCTA CATCCTACTC 660

TGTGGGTTTG AACCCTTCTT TGACCCAAGG GGGGACCAGT ACATGTACAG CCGCATCCTC 720

AATTGTGATT ATGAGTTTGT ATCTCCGTGG TGGGACGAGG TCTCTCTGAA TGCCAAGGAC 780

CTGGTTGGTA AGCTGATTGT CCTCGACCCA CACAAGCGCC TCAGTGTCCG GGAAGCCCTG 840

CAGCACCCCT GGGTGCTGGG CAAAGCTGCC CGCTTCTCAC ACATGGACAC CACGCAGAGG 900

AAGCTGCAGG AGTTCAATGC TCGACGCAAA CTTAAGGCTG CCATGAAAGC TGTTGTGGCC 960

ACCAGTCGAA TG 972

Domain Profile

S: 1     yklkeklGeGafsevlkakekktqkavaikvikkkalkgkeesveneiavlkklkhpniv  60

         y+l ++lG+Ga+s v++++ek+tqk++a+kv+kk+    +++ v++ei vl +l+hpni+

Q: 31    YTLGSELGRGATSIVYRCEEKQTQKPYAVKVLKKTI---DKKIVRTEIGVLLRLSHPNII  87

         88999***************************9998...89*******************

S: 61    alkdiyesksklylvlelvtGGelfdrivekgvytekdasevikqvleavkylhelgivh  120

         +lk+i+e+++ + lvlelvtGGelfdrive+g+y+e+da++vikq+leav+ylhe+g+vh

Q: 88    QLKEIFETDTDIALVLELVTGGELFDRIVERGYYSERDAAHVIKQILEAVAYLHENGVVH  147

         ************************************************************

S: 121   rdlkPenllylskeedskikiadfGlskleeke.llktacGtvgyvapevlkqkkyskkv  179

         rdlkPenlly++ + d+ +kiadfGlsk+ +++  +kt+cGt+gy+ape+l+ ++y+ +v

Q: 148   RDLKPENLLYADLSLDASLKIADFGLSKIIDDQvTMKTVCGTPGYCAPEILRGNAYGPEV  207

         ****************************88888689************************

S: 180   dvWsiGvityillcGyppfydekeekl.lekilkgeyefesPyWdeisesakdfikklle  238

         d+Ws+Gvi+yillcG++pf+d + +++  ++il+++yef sP+Wde+s +akd++ kl+

Q: 208   DMWSVGVILYILLCGFEPFFDPRGDQYmYSRILNCDYEFVSPWWDEVSLNAKDLVGKLIV  267

         *********************998886379******************************

S: 239   ldpekrytieqaledpWi  256

         ldp+kr+ +++al++pW+

Q: 268   LDPHKRLSVREALQHPWV  285

         *****************7

Domain Sequence
(FASTA)

YTLGSELGRG ATSIVYRCEE KQTQKPYAVK VLKKTIDKKI VRTEIGVLLR LSHPNIIQLK 60

EIFETDTDIA LVLELVTGGE LFDRIVERGY YSERDAAHVI KQILEAVAYL HENGVVHRDL 120

KPENLLYADL SLDASLKIAD FGLSKIIDDQ VTMKTVCGTP GYCAPEILRG NAYGPEVDMW 180

SVGVILYILL CGFEPFFDPR GDQYMYSRIL NCDYEFVSPW WDEVSLNAKD LVGKLIVLDP 240

HKRLSVREAL QHPWV 255

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013