EKS-ORL-00506

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORL-00506

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/ULK	323.7	1.1E-96	15	268	254

Status

Unreviewed

Ensembl Protein

ENSORLP00000017969

UniProt Accession

H2MH71;

Protein Name

Protein Synonyms/Alias

Gene Name

ULK3

Gene Synonyms/Alias

ULK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSORLG00000014330	ENSORLP00000017969	ENSORLT00000017970

Organism

Oryzias latipes

Functional Description

Protein Length

471

Protein Sequence
(FASTA)

MASTSSFAPP KLADFILTER LGSGTYATVY KAYRKGNSRE VVAVKVVAKK TLNKASTENL 60

LTEIEILKTV RHPHIVQLKD FQWDADNIYL ILEWCSGGDL SRFIRSRRIL PEIVARRFLQ 120

QIACALQFLH ERNISHLDLK PQNILLSGCV LKLADFGFAQ YMSPWDEKSV LRGSPLYMAP 180

EMVCRRQYDS RVDLWSVGVI LYEALFGRAP FASKSFAELE EKIRSDQPVE LPPGAKVSKD 240

CRDLLLRLLE RNPDARITFA EFFTHPFVDM EHMPSADSIE KAKELVLQAV QKDQEGERSS 300

ALSLYCSALE HFVPAIHYET DRQRKEALRQ KVKQYVSRAE ELKALLASDN KRSFEEARSA 360

RDVLREMSQD HPRLVAALNM ASTAIAKEES RSDDCEALDM YQQCLGELLL ALAAEPQGRR 420

KELLHSEIKT LMARAEYLKK HIKMQETQQD VSLDRESFAD SIRSCEFCTI S 471

Nucleotide Sequence
(FASTA)

ATGGCTTCAA CATCAAGTTT TGCCCCCCCA AAGCTGGCGG ACTTCATCCT GACAGAGAGG 60

CTGGGCAGTG GCACATATGC TACGGTCTAC AAAGCTTATA GGAAAGGGAA CAGTCGGGAG 120

GTGGTGGCAG TGAAGGTGGT CGCGAAGAAG ACTCTAAATA AGGCCTCCAC AGAAAACCTG 180

TTGACAGAAA TCGAAATCCT GAAAACTGTG CGTCATCCTC ATATTGTCCA GCTGAAGGAC 240

TTCCAGTGGG ACGCTGACAA CATTTACCTG ATCCTGGAAT GGTGCTCTGG AGGGGATCTC 300

TCCCGCTTTA TTCGCAGCCG CAGGATTTTA CCTGAGATTG TGGCCAGGCG GTTTCTGCAG 360

CAGATTGCCT GTGCCCTCCA GTTTCTTCAT GAGAGAAACA TCTCGCATTT GGATTTGAAG 420

CCTCAAAATA TTCTATTGAG CGGCTGTGTC CTTAAACTAG CAGATTTTGG TTTTGCCCAG 480

TACATGTCAC CGTGGGATGA GAAGAGCGTC CTCAGAGGCT CTCCTCTGTA CATGGCTCCC 540

GAGATGGTGT GTCGCCGGCA GTACGACTCC CGAGTGGATC TCTGGTCCGT GGGAGTCATT 600

CTTTACGAGG CTCTGTTTGG ACGCGCTCCG TTTGCATCAA AGTCCTTCGC CGAGTTGGAA 660

GAGAAGATCA GGAGTGACCA GCCTGTTGAG CTACCTCCCG GGGCCAAGGT ATCCAAGGAC 720

TGCAGGGATC TGCTGTTGCG GCTTTTGGAG AGAAATCCAG ATGCCCGGAT CACATTTGCA 780

GAGTTCTTCA CCCACCCTTT TGTGGATATG GAGCACATGC CAAGTGCAGA CAGTATCGAG 840

AAAGCAAAGG AGCTGGTGCT GCAGGCGGTT CAGAAAGACC AGGAGGGAGA GAGGTCTTCT 900

GCTCTGTCTC TTTACTGTAG TGCCCTTGAG CACTTTGTCC CCGCTATCCA CTATGAAACA 960

GACCGACAGC GTAAAGAAGC CCTGAGGCAG AAGGTCAAAC AGTACGTTTC CAGAGCCGAG 1020

GAGCTCAAAG CTCTGCTAGC TTCAGACAAC AAACGAAGCT TCGAAGAGGC CCGAAGTGCC 1080

AGAGATGTTC TCCGAGAAAT GTCTCAAGAC CATCCACGAC TGGTCGCTGC CTTGAATATG 1140

GCCTCTACAG CTATCGCTAA GGAGGAGAGT CGATCAGATG ATTGTGAGGC ACTGGACATG 1200

TACCAGCAAT GCTTAGGAGA GCTTTTGTTG GCGCTTGCAG CGGAGCCGCA GGGCCGGAGA 1260

AAAGAGCTGC TGCACAGTGA GATAAAAACC CTCATGGCGA GAGCAGAGTA CCTTAAAAAG 1320

CATATTAAGA TGCAGGAGAC TCAGCAGGAT GTTTCTCTGG ATCGGGAATC TTTCGCAGAT 1380

TCTATCAGAA GCTGTGAGTT TTGCACAATT TCT 1413

Domain Profile

S: 1     ysleeeiGkGsfavvykgrlrkktsqvvAikvvekkkl.kkslenlekeikilkelkhen  59

         ++l+e++G+G++a+vyk++ + ++++vvA+kvv+kk+l k+s+enl +ei+ilk ++h++

Q: 15    FILTERLGSGTYATVYKAYRKGNSREVVAVKVVAKKTLnKASTENLLTEIEILKTVRHPH  74

         7899***************99999**************9999******************

S: 60    ivalldveetskevylvmeycaggdLakllkqkkeLsedtvreflqqlasalkaLhskki  119

         iv+l+d++++++++yl++e+c+ggdL++++++++ L+e ++r+flqq+a al++Lh+++i

Q: 75    IVQLKDFQWDADNIYLILEWCSGGDLSRFIRSRRILPEIVARRFLQQIACALQFLHERNI  134

         ************************************************************

S: 120   vhrDlkPqniLlsyadakkelkkvtlkladFglarvlkeesmaatlkGsplYmaPEvvke  179

         +h DlkPqniLls            lkladFg+a++++ +++++ l+GsplYmaPE+v++

Q: 135   SHLDLKPQNILLS---------GCVLKLADFGFAQYMSPWDEKSVLRGSPLYMAPEMVCR  185

         *************.........899***********************************

S: 180   qqydakaDlWSiGtilyellvGkpPfaaesiseLvekiekndvleppipkeisselkdll  239

         +qyd+++DlWS+G+ilye+l+G++Pfa++s+ eL+eki++++ +e+p  +++s++++dll

Q: 186   RQYDSRVDLWSVGVILYEALFGRAPFASKSFAELEEKIRSDQPVELPPGAKVSKDCRDLL  245

         *****************************************999****************

S: 240   qsLLqrdpkkRisfeelfahpfl  262

          +LL+r+p +Ri+f+e+f+hpf+

Q: 246   LRLLERNPDARITFAEFFTHPFV  268

         *********************96

Domain Sequence
(FASTA)

FILTERLGSG TYATVYKAYR KGNSREVVAV KVVAKKTLNK ASTENLLTEI EILKTVRHPH 60

IVQLKDFQWD ADNIYLILEW CSGGDLSRFI RSRRILPEIV ARRFLQQIAC ALQFLHERNI 120

SHLDLKPQNI LLSGCVLKLA DFGFAQYMSP WDEKSVLRGS PLYMAPEMVC RRQYDSRVDL 180

WSVGVILYEA LFGRAPFASK SFAELEEKIR SDQPVELPPG AKVSKDCRDL LLRLLERNPD 240

ARITFAEFFT HPFV 254

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR007330	; MIT.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF04212	; MIT; 2.
PF00069	; Pkinase; 1.

SMARTs

SM00745	; MIT; 2.
SM00220	; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013