EKS-ORL-00082

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORL-00082

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	333.6	1.1E-99	26	335	310

Status

Unreviewed

Ensembl Protein

ENSORLP00000019100

UniProt Accession

H2MK92;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK19

Gene Synonyms/Alias

CDK19;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSORLG00000015247	ENSORLP00000019102	ENSORLT00000019103
ENSORLG00000015247	ENSORLP00000019100	ENSORLT00000019101

Organism

Oryzias latipes

Functional Description

Protein Length

489

Protein Sequence
(FASTA)

MDYDFKTKLA AERERVEDLF EYEGCKVGRG TYGHVYKAKR KDGKDEKEYA LKQIEGTGIS 60

MSACREIALL RELKHPNVIA LQKVFLSHSD RKVWLLFDYA EHDLWHIIKF HRASKANKKP 120

MQLPRGMVKS LLYQILDGIH YLHANWVLHR DLKPANILVM GEGPERGRVK IADMGFARLF 180

NSPLKPLADL DPVVVTFWYR APELLLGARH YTKAIDIWAI GCIFAELLTS EPIFHCRQED 240

IKTSNPFHHD QLDRIFTVMG FPADKDWEDI RKMPEYPTLQ KDFRRTTYTN SSLIKYMEKH 300

KVKPDSKVFL LLQKLLTMDP NKRITSELAL QDPYFLEDPL PTTDVFAGCQ IPYPKREFLN 360

EDEPEEKTEK KQTKQHQQTA GQTQTQNQQQ TTAQQAPSQQ SSAQTNGTTG GAGATGGGGL 420

QHSQDQGPPN KKPRLGPSGA SSGTGVLQSE YQHSSSRLGY QSNTQSSTQS QNTMGYSSSS 480

QQSSQYPRY 489

Nucleotide Sequence
(FASTA)

ATGGATTACG ACTTCAAAAC AAAGCTGGCA GCGGAGAGGG AGAGAGTGGA AGATCTTTTC 60

GAATATGAAG GTTGCAAAGT GGGTCGAGGC ACCTACGGGC ACGTTTATAA AGCTAAGCGC 120

AAAGACGGGA AGGATGAGAA GGAATATGCA CTGAAACAGA TTGAAGGCAC TGGAATCTCC 180

ATGTCTGCCT GCAGGGAAAT TGCTCTGCTG CGAGAGCTGA AGCACCCCAA CGTTATTGCC 240

CTGCAGAAGG TCTTCCTGTC CCACAGCGAC AGGAAGGTGT GGCTGCTCTT CGACTACGCC 300

GAGCATGACC TGTGGCACAT TATCAAGTTC CACCGCGCCT CCAAGGCCAA CAAGAAACCA 360

ATGCAACTTC CTCGCGGGAT GGTGAAGTCC CTGCTGTATC AGATTCTGGA CGGGATCCAC 420

TACCTCCACG CCAACTGGGT TCTCCACAGG GATTTGAAAC CAGCAAACAT CCTGGTGATG 480

GGAGAAGGTC CGGAGCGAGG AAGAGTCAAA ATAGCTGACA TGGGTTTCGC CCGACTCTTT 540

AACTCGCCCC TTAAGCCGCT GGCAGACCTC GATCCGGTGG TGGTGACCTT CTGGTACCGC 600

GCTCCTGAGC TCTTGCTGGG TGCCCGGCAC TACACCAAAG CTATTGACAT CTGGGCGATT 660

GGCTGCATCT TCGCAGAACT GCTGACGTCA GAACCCATTT TTCACTGTCG CCAAGAGGAC 720

ATCAAGACCA GCAACCCATT CCACCACGAC CAGCTAGACC GGATATTCAC CGTTATGGGT 780

TTCCCCGCAG ATAAAGACTG GGAAGACATC AGGAAGATGC CAGAGTACCC CACCCTTCAG 840

AAGGATTTTA GGAGGACAAC GTATACAAAC AGCAGCTTAA TCAAATACAT GGAGAAACAT 900

AAAGTGAAAC CCGACAGCAA GGTCTTCCTA TTGCTTCAGA AACTCCTCAC CATGGACCCT 960

AACAAGCGCA TCACATCTGA GCTGGCGCTG CAGGACCCCT ACTTCCTTGA GGACCCATTA 1020

CCGACCACAG ATGTGTTTGC TGGCTGTCAG ATTCCCTACC CCAAACGAGA GTTTCTGAAC 1080

GAAGACGAGC CCGAAGAGAA AACGGAAAAG AAACAAACCA AGCAGCACCA GCAGACGGCA 1140

GGCCAGACTC AGACCCAGAA CCAGCAACAG ACGACGGCCC AGCAGGCCCC CTCCCAGCAG 1200

AGCTCGGCCC AAACCAATGG CACCACTGGA GGCGCGGGAG CCACCGGCGG TGGGGGTCTG 1260

CAGCACAGTC AGGATCAGGG TCCACCCAAC AAGAAACCTC GGCTCGGGCC CTCTGGGGCT 1320

TCCTCAGGCA CGGGGGTTTT ACAGTCAGAA TACCAGCACT CCAGCTCCCG CCTCGGTTAC 1380

CAAAGCAACA CCCAAAGCTC CACCCAGTCC CAGAACACCA TGGGTTACTC TTCATCGTCT 1440

CAGCAGAGCT CTCAGTACCC TCGTTACTAA 1470

Domain Profile

S: 6     kigeGtygkvykakdke..tgevvAlKkirlekekegvpitalrEisllkelkhknivkL  63

         k+g+Gtyg+vykak+k+  +++ +AlK+i    e +g++++a+rEi+ll+elkh+n++ L

Q: 26    KVGRGTYGHVYKAKRKDgkDEKEYALKQI----EGTGISMSACREIALLRELKHPNVIAL  81

         79************986436678******....999************************

S: 64    levva.kdkkklyLvfefleqdLkkllkkkkkk.......klsleevkslllqlleglay  115

         ++v+  ++++k++L+f+++e+dL++++k ++++       +l++ +vksll+q+l+g++y

Q: 82    QKVFLsHSDRKVWLLFDYAEHDLWHIIKFHRASkankkpmQLPRGMVKSLLYQILDGIHY  141

         ****94555*********************99999999999*******************

S: 116   lHsnkilHRDlKpqNlLiske....gklklaDfGlarafssplk...tytkevvTlwYra  168

         lH+n++lHRDlKp+N+L++ e    g++k+aD+G+ar f+splk   +++++vvT+wYra

Q: 142   LHANWVLHRDLKPANILVMGEgperGRVKIADMGFARLFNSPLKplaDLDPVVVTFWYRA  201

         *******************9988889*************99999665699**********

S: 169   PelLlgakeYstavDiWsvgcilaelltrkplfqgkse.........idqlerifkllgt  219

         PelLlga++Y++a+DiW++gci+aellt++p+f++++e         +dql+rif+++g

Q: 202   PELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEdiktsnpfhHDQLDRIFTVMGF  261

         ************************************************************

S: 220   psekvwpevsklpeyk...ksfpkkkkk..klkekvkklk....ekaldllekllaldpk  270

         p +k+w++++k+pey    k+f++++++  +l ++++k k    +k + ll+kll++dp+

Q: 262   PADKDWEDIRKMPEYPtlqKDFRRTTYTnsSLIKYMEKHKvkpdSKVFLLLQKLLTMDPN  321

         ***************965457777666644566666443333545689************

S: 271   kRisakealqhkyf  284

         kRi+++ alq++yf

Q: 322   KRITSELALQDPYF  335

         *************9

Domain Sequence
(FASTA)

KVGRGTYGHV YKAKRKDGKD EKEYALKQIE GTGISMSACR EIALLRELKH PNVIALQKVF 60

LSHSDRKVWL LFDYAEHDLW HIIKFHRASK ANKKPMQLPR GMVKSLLYQI LDGIHYLHAN 120

WVLHRDLKPA NILVMGEGPE RGRVKIADMG FARLFNSPLK PLADLDPVVV TFWYRAPELL 180

LGARHYTKAI DIWAIGCIFA ELLTSEPIFH CRQEDIKTSN PFHHDQLDRI FTVMGFPADK 240

DWEDIRKMPE YPTLQKDFRR TTYTNSSLIK YMEKHKVKPD SKVFLLLQKL LTMDPNKRIT 300

SELALQDPYF 310

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013