EKS-ORL-00255

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORL-00255

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NKF2	446.6	6.6E-134	152	510	359

Status

Unreviewed

Ensembl Protein

ENSORLP00000020035

UniProt Accession

H2MMT9;

Protein Name

Protein Synonyms/Alias

Gene Name

PINK1

Gene Synonyms/Alias

PINK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSORLG00000016007	ENSORLP00000020035	ENSORLT00000020036

Organism

Oryzias latipes

Functional Description

Protein Length

588

Protein Sequence
(FASTA)

VSKNPSGLTM SVKHAISRGL ELGRSIFQLG VLKAGSRVAA KLRADRVRAG PAFRTAQPQA 60

FLPLRYRYYR TSLRGLAAQL QWAGFVRRFA GGSPRNRAVF LAFGLGVGLI EKQIEDDRLS 120

LATCNEIKAV FRKKKFQSPL KPLAYGYKLE DYIVGNQIGK GSNAAVYEAA PQFFCSKKSD 180

GEPAAVQIRD SEGEEGNRVM PSLSCCSLRN FPLAIKMLWN FGAGSSNEAI FRSMSHELVP 240

TDPLALAPAK QQLTLDGNFG VVPRRVSAHP NVIRVYRAFT ADVPLLPGAQ DEYPDVLPAR 300

LNPSGLGNNR TLFLVMKNYP FSLRQYLQVC TPSRKQRSVM VLQLLEGVDH LCKQGVAHRD 360

LKSDNVLLEF DSGTDGCPRL VITDFGCCLA ESEQSLQLPF NSQWVDRGGN ASLMAPEVAS 420

AVPGRRVVID YSKADAWAVG AISYEIFGEP NPFYHAVGLH SISYQEKQLP ILHSSAPADV 480

QLVIRLLLRR SPTKRPSARV AANMLHLTLW GQRILDKQGN AGMRKLAEWL LCQSAVVLLK 540

GCSGPAGNRV EAELQRNFLR NLELEELRTA MGFLIYGRNQ HTARIPSA 588

Nucleotide Sequence
(FASTA)

GTTTCTAAAA ACCCTTCTGG GCTCACAATG TCTGTTAAAC ACGCTATTAG CCGAGGGCTG 60

GAGTTGGGCC GGTCGATTTT TCAGCTGGGG GTCCTGAAAG CAGGTAGTCG GGTCGCAGCG 120

AAGCTCCGAG CTGACCGAGT TCGTGCGGGC CCGGCCTTCC GGACCGCTCA GCCTCAGGCT 180

TTCCTGCCTC TCCGATACCG GTATTACCGC ACCTCACTGA GGGGTCTGGC AGCTCAGCTC 240

CAGTGGGCTG GCTTCGTTAG GAGGTTTGCC GGAGGTTCAC CGCGGAACAG AGCCGTCTTT 300

CTGGCGTTTG GCCTCGGTGT GGGATTAATC GAGAAGCAGA TTGAGGACGA CAGGCTGAGT 360

TTGGCAACGT GCAATGAGAT AAAGGCGGTG TTCAGAAAGA AGAAGTTCCA GAGCCCGCTC 420

AAGCCCTTGG CCTATGGATA CAAACTGGAG GATTACATTG TAGGAAACCA GATTGGGAAA 480

GGATCCAACG CAGCTGTGTA TGAAGCTGCA CCTCAGTTTT TCTGCTCCAA GAAAAGCGAT 540

GGTGAGCCCG CCGCGGTGCA GATACGAGAC AGTGAGGGCG AGGAAGGAAA TCGCGTCATG 600

CCATCTCTGA GTTGCTGCTC TCTAAGGAAC TTCCCGCTGG CAATCAAGAT GCTGTGGAAC 660

TTTGGGGCAG GGTCATCAAA CGAGGCGATC TTTAGATCGA TGTCCCATGA GCTGGTTCCC 720

ACAGACCCCC TCGCTCTGGC GCCAGCAAAA CAGCAACTTA CTTTAGACGG AAACTTTGGA 780

GTCGTGCCCA GACGCGTGTC AGCTCACCCC AACGTGATCA GAGTGTACCG GGCGTTCACA 840

GCGGACGTCC CGCTGCTGCC AGGCGCTCAG GACGAGTATC CAGACGTGCT TCCTGCCAGG 900

CTCAACCCCA GCGGCCTGGG CAACAATCGC ACTCTGTTTT TGGTGATGAA AAACTACCCC 960

TTCTCGCTCC GTCAGTACCT GCAAGTGTGC ACGCCAAGCC GCAAGCAGAG ATCTGTGATG 1020

GTGCTGCAGC TCCTGGAGGG TGTGGACCAT CTGTGCAAGC AGGGCGTTGC TCACAGGGAT 1080

CTCAAATCAG ACAACGTGCT GCTGGAGTTT GACTCGGGCA CAGATGGTTG CCCCCGTTTA 1140

GTGATCACAG ACTTCGGCTG CTGTCTGGCT GAAAGTGAGC AGAGTTTGCA GCTGCCCTTC 1200

AACAGCCAGT GGGTGGACAG AGGGGGGAAT GCCTCTCTTA TGGCCCCTGA GGTGGCCTCT 1260

GCAGTCCCTG GGCGCAGAGT CGTGATCGAC TACAGCAAGG CCGATGCGTG GGCTGTGGGC 1320

GCCATTTCCT ACGAGATTTT TGGTGAACCA AATCCATTCT ACCATGCTGT TGGACTGCAT 1380

AGCATCAGCT ACCAGGAGAA GCAGCTCCCT ATCCTGCATT CCAGTGCCCC CGCTGATGTG 1440

CAGTTAGTGA TTCGATTACT CCTCAGGAGG AGTCCTACAA AGCGCCCCAG TGCTCGTGTA 1500

GCAGCAAACA TGCTGCACCT CACCCTTTGG GGTCAGAGGA TTCTGGATAA ACAGGGAAAT 1560

GCTGGCATGA GAAAGCTGGC TGAGTGGTTA CTGTGCCAGT CTGCTGTGGT TCTGCTGAAG 1620

GGCTGCAGTG GACCTGCTGG GAACAGGGTG GAGGCGGAGC TTCAGAGGAA CTTCCTGAGG 1680

AACCTGGAGC TTGAGGAGCT GCGCACAGCG ATGGGCTTCC TCATCTACGG ACGAAACCAG 1740

CACACGGCCC GCATCCCGTC TGCTTAG 1767

Domain Profile

S: 1     yligealgkgcnaavyeatlatldqelekakhlgll..gkevtvvlaeidqesavaakkf  58

         y +g+ +gkg naavyea      ++ +  +   +     e +   + +++ s  + ++f

Q: 152   YIVGNQIGKGSNAAVYEAAPQFFCSKKSDGEPAAVQirDSEGEEGNRVMPSLSCCSLRNF  211

         899***************87766555555554444411445556667788899999****

S: 59    plaiklmfnieadssseallksmsqelvpasrva.........ldgeygavpkllakhPn  109

         plaik+++n+ a+ss+ea+++sms+elvp+   a         ldg++g vp++++ hPn

Q: 212   PLAIKMLWNFGAGSSNEAIFRSMSHELVPTDPLAlapakqqltLDGNFGVVPRRVSAHPN  271

         *****************************876665566677779****************

S: 110   ivrvlrafidsvkllPdalldyPdalparlypeglgegktlylvmkrydqtlreylesqd  169

         ++rv+raf+ +v+llP+a  +yPd+lparl+p+glg+++tl+lvmk+y+ +lr+yl++ +

Q: 272   VIRVYRAFTADVPLLPGAQDEYPDVLPARLNPSGLGNNRTLFLVMKNYPFSLRQYLQVCT  331

         ************************************************************

S: 170   rstrlaalllaqlleavdhlvkhgvahrdlksdnilveld..ddeiPvlviadfGCclad  227

         +s +++ ++++qlle+vdhl k+gvahrdlksdn+l+e+d   d++P lvi+dfGCcla+

Q: 332   PSRKQRSVMVLQLLEGVDHLCKQGVAHRDLKSDNVLLEFDsgTDGCPRLVITDFGCCLAE  391

         ****************************************888*****************

S: 228   kvdglrlpyessevdkGGnaalmaPeistavpGpsavinyekadtWavGalayeifglsn  287

           ++l+lp++s+ vd+GGna+lmaPe+++avpG+++vi+y+kad+WavGa++yeifg+ n

Q: 392   SEQSLQLPFNSQWVDRGGNASLMAPEVASAVPGRRVVIDYSKADAWAVGAISYEIFGEPN  451

         ************************************************************

S: 288   PfygegkaslesasyqeaqlPalpesvppelrqlvydllkreaskrvsadiaanvlqlsl  347

         Pfy   +  l+s syqe+qlP l +s p +++ +++ ll+r ++kr+sa++aan+l+l+l

Q: 452   PFY--HAVGLHSISYQEKQLPILHSSAPADVQLVIRLLLRRSPTKRPSARVAANMLHLTL  509

         ***..8899**************************************************9

S: 348   f  348

Q: 510   W  510

Domain Sequence
(FASTA)

YIVGNQIGKG SNAAVYEAAP QFFCSKKSDG EPAAVQIRDS EGEEGNRVMP SLSCCSLRNF 60

PLAIKMLWNF GAGSSNEAIF RSMSHELVPT DPLALAPAKQ QLTLDGNFGV VPRRVSAHPN 120

VIRVYRAFTA DVPLLPGAQD EYPDVLPARL NPSGLGNNRT LFLVMKNYPF SLRQYLQVCT 180

PSRKQRSVMV LQLLEGVDHL CKQGVAHRDL KSDNVLLEFD SGTDGCPRLV ITDFGCCLAE 240

SEQSLQLPFN SQWVDRGGNA SLMAPEVASA VPGRRVVIDY SKADAWAVGA ISYEIFGEPN 300

PFYHAVGLHS ISYQEKQLPI LHSSAPADVQ LVIRLLLRRS PTKRPSARVA ANMLHLTLW 359

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xiphophorus maculatus"; ?>