EKS-ORL-00184

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORL-00184

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/TLK	602.0	1.6E-181	441	719	279

Status

Unreviewed

Ensembl Protein

ENSORLP00000021626

UniProt Accession

H2MS90;

Protein Name

Protein Synonyms/Alias

Gene Name

TLK1 (1 of 2)

Gene Synonyms/Alias

TLK1 (1 of 2);

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSORLG00000017283	ENSORLP00000021626	ENSORLT00000021627

Organism

Oryzias latipes

Functional Description

Protein Length

749

Protein Sequence
(FASTA)

TMEELHSLDP RRQELLEARF MGGVGGSTGG LTNNECSNQS FGSLGSSSDK ELETPEKKQS 60

EGARGRKRKP EIQSESSQGK SGVRGPKISD YFDFQGGNGS SPVRGLPLVL RSPQNSHSLS 120

AQGTALLLFL GLNKMLLLQV RQNCSSPTCL SFGDHIMHPK HLAAKFVQVM HNYIYYDTSF 180

DNLSLELLKA LTDLTMLKLA ALESTKNLDL EKKEGRIDDL LRANCDLRRQ IDEQQKLLEK 240

YKERLNKCIT MSKKLLIEKS TQEKQACREK SMQDRLRLGH FTTVRHGASF TEQWTDGYAF 300

QKIVKQQEWI NQQREDIERQ RKLLAKRKPP SSSSSQAPAT NSESKQRKTK AVNGAESDPF 360

LKPSLPQLFV SLVRLTLAEY HEQEEIFKLR LGHLKKEEAE IQAELERLER VRNLHIRELK 420

RINNEDSSQR FKDHPTLNER YLLLHLLGRG GFSEVYKAFD LIEQRYAAVK IHQLNKNWRE 480

EKKENYHKHA CREYRIHKEL DHPRIVKLYD YFSLDTDTFC TVMEFCEGND LDFYLKQHKL 540

MSEKEARSIV MQIVNALKYL NEIKPPIIHY DLKPGNILLV DGTACGEIKI TDFGLSKIMD 600

DDNYGVDGMD LTSQGAGTYW YLPPECFVVG KEPPKISNKV DVWSVGIIFF QCLYGRKPFG 660

HNQSQQDILQ ENTILKATEV QFPVKPVVSN EAKAFIRRCL AYRKEDRSDV HQLGSDLYLL 720

PHIRRSSSSG NLQMSAAGSG LAPPSIISN 749

Nucleotide Sequence
(FASTA)

ACCATGGAGG AGCTTCACAG CCTGGACCCC AGGAGACAGG AGCTGCTGGA AGCACGTTTT 60

ATGGGTGGGG TTGGTGGCAG CACTGGGGGA TTGACCAATA ATGAATGTTC AAATCAGAGC 120

TTTGGAAGTC TAGGATCCTC CAGTGATAAG GAGTTAGAGA CTCCGGAGAA AAAACAGTCT 180

GAAGGAGCCA GAGGCAGAAA AAGGAAACCT GAGATCCAGT CAGAGAGCAG CCAAGGAAAG 240

TCAGGTGTCC GAGGACCCAA AATAAGCGAT TATTTTGATT TCCAGGGGGG AAATGGCTCC 300

AGTCCAGTGA GAGGTCTCCC TTTAGTGCTG CGCTCACCCC AGAACTCACA TTCCCTCTCT 360

GCTCAGGGCA CCGCTCTTCT CCTTTTTCTG GGTCTTAATA AAATGCTCCT CTTGCAGGTT 420

AGACAAAATT GTTCATCTCC CACCTGTCTG TCGTTTGGGG ACCACATCAT GCATCCAAAG 480

CATCTAGCAG CCAAATTTGT CCAGGTGATG CATAACTATA TATACTATGA TACAAGTTTT 540

GATAATTTGA GTCTTGAGTT GTTAAAAGCT CTTACGGACC TTACAATGTT GAAACTGGCT 600

GCTCTTGAAA GCACTAAGAA TCTAGACCTT GAGAAAAAAG AGGGCAGAAT AGATGACTTA 660

CTAAGGGCAA ACTGTGATCT CAGGAGGCAG ATAGATGAGC AACAAAAATT ACTTGAAAAG 720

TATAAGGAAC GTTTGAATAA GTGCATCACC ATGAGCAAGA AGTTGCTTAT AGAGAAGAGC 780

ACACAGGAGA AGCAGGCCTG TCGAGAGAAG AGCATGCAGG ACAGACTACG TTTAGGCCAT 840

TTCACTACAG TGAGACATGG AGCCTCATTC ACAGAGCAGT GGACCGACGG CTACGCCTTT 900

CAAAAAATTG TCAAGCAGCA AGAGTGGATA AACCAACAGA GAGAAGACAT TGAAAGGCAA 960

AGAAAACTTC TTGCCAAGAG GAAGCCTCCA TCTTCCAGCA GCTCCCAAGC ACCAGCCACA 1020

AACTCTGAGT CTAAACAACG CAAAACCAAG GCTGTGAACG GAGCGGAAAG CGATCCCTTT 1080

CTGAAACCCA GTCTACCTCA ACTATTTGTC TCTTTGGTAA GGCTGACACT GGCAGAGTAC 1140

CACGAACAGG AAGAGATCTT CAAACTGCGA CTGGGACACC TGAAGAAGGA AGAAGCTGAG 1200

ATCCAGGCAG AACTGGAGCG TTTAGAGAGG GTCCGCAACC TTCACATTAG GGAGCTGAAG 1260

AGAATAAATA ATGAAGACAG CTCCCAGAGA TTCAAAGATC ATCCAACACT GAATGAACGG 1320

TATCTGCTCC TGCACCTTTT AGGCAGAGGC GGCTTTAGTG AAGTTTACAA GGCCTTTGAC 1380

TTGATTGAGC AGCGATATGC TGCAGTGAAA ATTCACCAAC TCAACAAGAA CTGGAGAGAA 1440

GAAAAGAAAG AGAACTATCA CAAGCACGCA TGTCGAGAGT ACAGAATACA CAAGGAGCTG 1500

GACCACCCCC GGATCGTAAA ACTTTACGAC TACTTCTCAT TGGACACAGA CACGTTTTGC 1560

ACTGTGATGG AGTTTTGCGA AGGGAACGAC TTGGATTTCT ACTTGAAGCA GCATAAGCTA 1620

ATGTCAGAGA AAGAGGCGCG CTCCATCGTC ATGCAGATAG TGAACGCGCT CAAATACCTA 1680

AATGAAATCA AACCGCCTAT TATACATTAT GACCTTAAAC CAGGGAACAT CCTGTTGGTG 1740

GACGGCACAG CCTGTGGAGA AATTAAAATC ACTGACTTTG GTCTTTCTAA AATCATGGAT 1800

GACGACAACT ATGGAGTAGA TGGAATGGAT CTGACATCGC AGGGTGCAGG AACCTATTGG 1860

TACCTGCCAC CTGAATGTTT TGTGGTTGGT AAAGAACCTC CCAAAATCTC CAATAAGGTG 1920

GATGTGTGGT CAGTGGGCAT CATTTTTTTC CAGTGTCTGT ATGGAAGGAA ACCTTTTGGT 1980

CACAACCAGT CACAGCAGGA CATTCTGCAG GAGAACACCA TCCTCAAAGC TACAGAGGTC 2040

CAGTTCCCTG TGAAGCCCGT CGTTAGCAAT GAAGCAAAGG CCTTCATCAG AAGGTGCTTG 2100

GCGTACAGAA AGGAGGACCG GAGCGATGTT CACCAGCTGG GAAGTGACCT CTACCTGCTC 2160

CCTCACATAC GAAGATCAAG TTCGTCTGGG AATCTACAGA TGAGCGCGGC GGGCTCGGGG 2220

CTAGCTCCCC CCAGCATCAT CTCAAACTGA 2250

Domain Profile

S: 1     ylllkllgkggfsevykafdlkeqryvavkihqlnkdwkdekkenyvkhalreyrihkel  60

         ylll+llg+ggfsevykafdl eqry+avkihqlnk+w++ekkeny+kha+reyrihkel

Q: 441   YLLLHLLGRGGFSEVYKAFDLIEQRYAAVKIHQLNKNWREEKKENYHKHACREYRIHKEL  500

         9***********************************************************

S: 61    dhprivklydllsldtdsfctvleyvegndldfylkqhkllsekearsiimqivsalkyl  120

         dhprivklyd++sldtd+fctv+e++egndldfylkqhkl+sekearsi+mqiv+alkyl

Q: 501   DHPRIVKLYDYFSLDTDTFCTVMEFCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALKYL  560

         ************************************************************

S: 121   neikppiihydlkpgnillvegtacgeikitdfglskimdddsydsddgleltsqgagty  180

         neikppiihydlkpgnillv+gtacgeikitdfglskimddd+y++d g++ltsqgagty

Q: 561   NEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDNYGVD-GMDLTSQGAGTY  619

         *********************************************99.************

S: 181   wylppecfvvgkeppkisnkvdvwsvgvifyqclygkkpfghnqsqqdileentilkate  240

         wylppecfvvgkeppkisnkvdvwsvg+if+qclyg+kpfghnqsqqdil+entilkate

Q: 620   WYLPPECFVVGKEPPKISNKVDVWSVGIIFFQCLYGRKPFGHNQSQQDILQENTILKATE  679

         ************************************************************

S: 241   vqfpskpvvsseakafirrclayrkedridvqqlakdeyl  280

         vqfp+kpvvs+eakafirrclayrkedr dv+ql +d yl

Q: 680   VQFPVKPVVSNEAKAFIRRCLAYRKEDRSDVHQLGSDLYL  719

         ***********************************99886

Domain Sequence
(FASTA)

YLLLHLLGRG GFSEVYKAFD LIEQRYAAVK IHQLNKNWRE EKKENYHKHA CREYRIHKEL 60

DHPRIVKLYD YFSLDTDTFC TVMEFCEGND LDFYLKQHKL MSEKEARSIV MQIVNALKYL 120

NEIKPPIIHY DLKPGNILLV DGTACGEIKI TDFGLSKIMD DDNYGVDGMD LTSQGAGTYW 180

YLPPECFVVG KEPPKISNKV DVWSVGIIFF QCLYGRKPFG HNQSQQDILQ ENTILKATEV 240

QFPVKPVVSN EAKAFIRRCL AYRKEDRSDV HQLGSDLYL 279

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013