EKS-ORL-00289

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORL-00289

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	388.4	1.5E-116	53	304	252

Status

Unreviewed

Ensembl Protein

ENSORLP00000022432

UniProt Accession

H2MUG7;

Protein Name

Protein Synonyms/Alias

Gene Name

MARK3

Gene Synonyms/Alias

MARK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSORLG00000017921	ENSORLP00000022434	ENSORLT00000022435
ENSORLG00000017921	ENSORLP00000022432	ENSORLT00000022433
ENSORLG00000017921	ENSORLP00000022431	ENSORLT00000022432

Organism

Oryzias latipes

Functional Description

Protein Length

690

Protein Sequence
(FASTA)

WVTADARRRS NRMSSLQHTS HSNGRSDLGT RSSRTGVRTR SSDESQPPHV GNYRLLKTIG 60

KGNFAKVKLA RHILTGREVA IKIIDKTQLN PNSLQKLFRE VRIMKILNHP NIVKLFEVIE 120

TDRTLYLVME YASGGEVFDY LVAHGRMKEK EARAKFRQIV SAVQYCHQKH IVHRDLKAEN 180

LLLDADMNIK IADFGFSNEF TLGNKLDTFC GSPPYAAPEL FQGKKYDGPE VDVWSLGVIL 240

YTLVSGSLPF DGQNLKELRE RVLRGKYRIP FYMSTDCENL LKRFLVLNPA KRGTLEQIMK 300

DRWINAGFEE DELKPYTEPE LDITDQKRID VMVGMGYKLE DIQESLTKMK YDQFTATYLL 360

LGRKASEVGA PGSRNASLAK PRPSSELNGQ SPSHLKVQRS VSSNHKQRRY SEQVGQNVPP 420

GMTHPKRSQT TTGESNAKEE AGVQKPSTPG GRGAPPSSPL LGNANNPNKA DIPDRRKGGT 480

TGPATNSASA GMTRRNTYVC SDRNNADRLS VIPNGKENSV AVSPGGQRNP VASTHSIANS 540

TTPDRLRFPR GTASRSTFHG GQLRDRRTAT YNGPPASPTL SHDATPLSQT RSRGTSNLFS 600

KLTSKLTRRI TGVLLLVGGP DTLTVVRHVP GDQKGEGKDG KPRSLRFTWS MRTTTSMEPC 660

DIMEEIFKVL DANDCNYKQQ ESFLLLCFHG 690

Nucleotide Sequence
(FASTA)

TGGGTCACAG CTGACGCACG GAGACGCTCT AACAGGATGT CCTCTCTGCA GCACACCTCG 60

CACAGCAACG GCCGCTCGGA CCTCGGCACG CGCTCCAGCC GGACCGGCGT TCGAACCCGC 120

AGCTCCGACG AGTCGCAGCC ACCCCACGTC GGAAACTACC GCCTGCTCAA AACCATCGGC 180

AAGGGCAACT TCGCCAAAGT CAAACTGGCC CGGCACATCC TCACAGGCAG GGAGGTGGCA 240

ATTAAGATCA TAGACAAGAC TCAGCTGAAC CCCAACAGCC TACAGAAGCT CTTCAGAGAA 300

GTCCGAATAA TGAAGATCTT GAATCATCCT AATATTGTCA AACTGTTTGA GGTGATCGAA 360

ACGGACCGGA CGCTCTACCT GGTCATGGAG TACGCCAGCG GAGGAGAGGT GTTCGACTAC 420

CTGGTTGCAC ATGGAAGAAT GAAGGAAAAA GAGGCCAGAG CTAAATTTAG ACAGATCGTG 480

TCAGCGGTGC AGTACTGCCA CCAGAAGCAC ATCGTTCACC GTGACCTCAA GGCCGAGAAC 540

CTCCTCCTCG ACGCAGACAT GAACATAAAG ATCGCAGATT TTGGCTTCAG CAACGAGTTC 600

ACCCTGGGCA ACAAGCTGGA CACGTTCTGC GGCTCGCCGC CGTACGCGGC GCCGGAGCTG 660

TTCCAGGGCA AGAAATACGA CGGGCCGGAG GTGGACGTGT GGAGTCTGGG GGTCATCCTG 720

TACACGCTGG TCAGCGGCTC GCTGCCCTTC GATGGACAGA ACCTGAAGGA GCTGCGGGAG 780

CGCGTCCTCA GAGGGAAGTA CCGCATTCCC TTCTACATGT CCACCGACTG CGAGAACCTC 840

CTCAAACGCT TCCTGGTCCT CAACCCGGCC AAGCGGGGTA CTCTCGAGCA AATCATGAAG 900

GATCGATGGA TCAACGCCGG GTTTGAGGAG GACGAGCTGA AGCCGTACAC GGAGCCGGAG 960

CTGGACATCA CAGACCAGAA GAGAATAGAT GTGATGGTGG GGATGGGCTA CAAGCTGGAG 1020

GACATCCAGG AATCTCTGAC CAAGATGAAG TACGACCAGT TCACAGCCAC CTACCTGCTG 1080

CTGGGCAGGA AGGCCTCTGA GGTAGGAGCA CCAGGCAGCC GTAATGCGTC TTTGGCCAAA 1140

CCCAGACCTA GCAGCGAGCT CAACGGCCAG TCGCCATCCC ACCTCAAAGT CCAGAGAAGT 1200

GTTTCCTCCA ACCACAAACA GAGACGATAC AGCGAGCAAG TCGGGCAGAA CGTCCCTCCG 1260

GGGATGACCC ATCCAAAGAG GAGTCAGACC ACCACAGGGG AAAGCAACGC CAAGGAGGAG 1320

GCCGGCGTCC AGAAACCCAG CACCCCAGGC GGACGCGGCG CTCCCCCCTC CAGCCCTTTG 1380

CTGGGCAACG CCAACAACCC CAACAAGGCA GACATCCCTG ACCGCAGGAA AGGGGGCACC 1440

ACCGGCCCCG CTACTAACTC GGCGTCAGCA GGCATGACCC GCAGGAACAC GTATGTGTGC 1500

AGCGACAGGA ACAACGCGGA CCGCCTCTCC GTCATTCCCA ACGGGAAGGA GAACAGTGTC 1560

GCCGTGTCTC CTGGCGGGCA GAGGAACCCT GTGGCGTCCA CCCACAGCAT CGCCAACAGC 1620

ACCACACCCG ACCGCCTCCG CTTCCCCCGA GGCACGGCCA GCCGCAGCAC CTTCCACGGC 1680

GGCCAGCTGA GAGACCGCCG CACCGCCACG TACAACGGGC CCCCGGCCTC GCCCACGCTG 1740

TCACACGACG CCACGCCCCT GTCCCAAACC CGCAGCCGTG GAACCAGCAA CCTCTTCTCC 1800

AAACTCACGT CTAAACTCAC ACGCAGAATC ACTGGTGTAT TATTGCTGGT GGGGGGCCCC 1860

GACACCCTCA CTGTAGTTCG CCATGTACCT GGGGATCAAA AAGGGGAAGG TAAAGACGGG 1920

AAGCCCCGCT CCCTCAGGTT CACCTGGAGT ATGAGGACCA CCACCTCCAT GGAACCCTGC 1980

GACATCATGG AGGAAATCTT CAAGGTGCTC GACGCCAACG ACTGCAACTA CAAACAGCAA 2040

GAGAGCTTCC TGCTTCTGTG TTTCCATGGA 2070

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkklseeslekikrEieilkklkhpni  60

         y+llkt+G+g+f+kVkla+h +t+++va+Kii+k++l+ +sl+k++rE++i+k+l+hpni

Q: 53    YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPNSLQKLFREVRIMKILNHPNI  112

         99**********************************************************

S: 61    ikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgiv  120

         +kl+eviet+++lylv+eyasgge+fdy++++gr+kekear+ f+q+vsav+Y+h+k+iv

Q: 113   VKLFEVIETDRTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKHIV  172

         ************************************************************

S: 121   HrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkvD  180

         HrDlK+eNllld+++nikiaDFG++n+f+ g++l+tfcGsppYaaPel++gkkY+gp+vD

Q: 173   HRDLKAENLLLDADMNIKIADFGFSNEFTLGNKLDTFCGSPPYAAPELFQGKKYDGPEVD  232

         ************************************************************

S: 181   vWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpekR  240

         vWslGv+Ly+lv+g+lPfd++nlkel+e++l+gk++ip+++s+++e+Ll+++Lv +p+kR

Q: 233   VWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPAKR  292

         ************************************************************

S: 241   atieeilkhewl  252

          t+e+i+k++w+

Q: 293   GTLEQIMKDRWI  304

         ***********7

Domain Sequence
(FASTA)

YRLLKTIGKG NFAKVKLARH ILTGREVAIK IIDKTQLNPN SLQKLFREVR IMKILNHPNI 60

VKLFEVIETD RTLYLVMEYA SGGEVFDYLV AHGRMKEKEA RAKFRQIVSA VQYCHQKHIV 120

HRDLKAENLL LDADMNIKIA DFGFSNEFTL GNKLDTFCGS PPYAAPELFQ GKKYDGPEVD 180

VWSLGVILYT LVSGSLPFDG QNLKELRERV LRGKYRIPFY MSTDCENLLK RFLVLNPAKR 240

GTLEQIMKDR WI 252

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Sarcophilus harrisii"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR001772	; Kinase-assoc_KA1.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR015940	; UBA/transl_elong_EF1B_N_euk.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220	; S_TKc; 1.
SM00165	; UBA; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.
PS50030	; UBA; 1.

Prints

Created Date

20-Feb-2013