EKS-ORL-00412

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORL-00412

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/PEK	224.6	1.9E-66	9	242	234

Status

Unreviewed

Ensembl Protein

ENSORLP00000023678

UniProt Accession

H2MXL1;

Protein Name

Protein Synonyms/Alias

Gene Name

EIF2AK2 (1 of 2)

Gene Synonyms/Alias

EIF2AK2 (1 of 2);

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSORLG00000018980	ENSORLP00000023678	ENSORLT00000023679
ENSORLG00000018980	ENSORLP00000023685	ENSORLT00000023686

Organism

Oryzias latipes

Functional Description

Protein Length

251

Protein Sequence
(FASTA)

RFTSEYDCIE GLGRGKFGFV YKAKRKLEGT DCAVKIVRYK KEALREVKVL SDLNHCNIVR 60

YYICWIEDSA PQWDGSTDSS SSAQSSSDSP VKYLYIHMEL CDTKTLRAWI DEKNMQDPKK 120

PCKRREEGLG VALQIVNGVE HIHSKTLIHR DLKPANILFD RNGMVKIGDF GLVTAEIEDD 180

AENQKERSGF KGTPSYMAPE QKRQTVYNNK VDIFALGLIY FELLWNFPTF HERNENIASA 240

ERLEFSRKSP D 251

Nucleotide Sequence
(FASTA)

AGGTTTACGT CCGAGTATGA CTGCATCGAA GGCCTGGGTA GAGGAAAGTT CGGTTTTGTC 60

TACAAGGCCA AACGAAAACT GGAGGGGACC GATTGTGCTG TGAAGATTGT GCGCTACAAA 120

AAAGAAGCTC TGCGAGAGGT GAAGGTACTG TCCGACCTCA ACCACTGCAA CATCGTCCGC 180

TACTACATAT GTTGGATAGA AGACTCCGCT CCTCAGTGGG ACGGCTCAAC GGACAGCAGC 240

TCTTCAGCGC AGTCGTCCAG CGATTCGCCT GTAAAGTACC TCTACATTCA TATGGAGCTG 300

TGTGACACTA AAACGCTGAG GGCGTGGATA GATGAGAAGA ACATGCAGGA CCCAAAGAAA 360

CCCTGTAAAA GACGGGAGGA GGGTCTAGGC GTCGCCCTGC AGATAGTGAA CGGAGTGGAG 420

CACATTCACT CCAAGACGCT CATCCACAGG GACCTGAAGC CTGCAAACAT CTTGTTTGAT 480

CGGAACGGAA TGGTGAAGAT CGGAGACTTT GGCCTCGTCA CAGCCGAGAT CGAAGATGAC 540

GCTGAGAACC AGAAGGAGAG AAGTGGGTTC AAAGGGACCC CGTCCTACAT GGCTCCTGAG 600

CAGAAAAGAC AAACCGTTTA TAACAATAAA GTAGATATAT TTGCCTTGGG CCTGATCTAC 660

TTCGAACTCC TTTGGAACTT CCCAACTTTT CATGAAAGGA ATGAGAATAT AGCTTCTGCA 720

GAGCGGCTGG AGTTCAGTAG AAAGTCACCA GAC 753

Domain Profile

S: 4     ikvlGkGgfgvVlkaknkldkkeyaikriklnkakkelekverevkaLaklehpnivrYf  63

         i+ lG+G fg V+kak+kl++++ a+k ++++k      +++revk+L+ l+h nivrY+

Q: 9     IEGLGRGKFGFVYKAKRKLEGTDCAVKIVRYKK------EALREVKVLSDLNHCNIVRYY  62

         6789***************************99......56*******************

S: 64    aawleekeesltdsseveaeaeleesesseesdtkllyiqmelceketLkdwiderklle  123

          +w+e+   +++      +  ++++ +ss++s +k+lyi melc+ +tL+ wide++++

Q: 63    ICWIEDSAPQWD-----GSTDSSSSAQSSSDSPVKYLYIHMELCDTKTLRAWIDEKNMQD  117

         ***********3.....233334455566777899*********************7444

S: 124   srselvm......rlfkqllegleylHskgliHrdLkpsniFldsddqvKigDFgLatal  177

          ++           ++ q+++g+e++Hsk liHrdLkp ni++d ++ vKigDFgL+ta+

Q: 118   PKK-PCKrreeglGVALQIVNGVEHIHSKTLIHRDLKPANILFDRNGMVKIGDFGLVTAE  176

         333.3333566669*********************************************9

S: 178   aealkedvkqdaqskeakhtgqvgtklymsPeqleksqYnkkvDifsLGlilfeLlypfs  237

         +e+  e        +++++ g  gt +ym+Peq ++  Yn+kvDif+LGli feLl  f

Q: 177   IEDDAE--------NQKERSGFKGTPSYMAPEQKRQTVYNNKVDIFALGLIYFELLWNFP  228

         888665........33356899**************************************

S: 238   temervetltelrd  251

         t  er e +++

Q: 229   TFHERNENIASAER  242

         ****9988776655

Domain Sequence
(FASTA)

IEGLGRGKFG FVYKAKRKLE GTDCAVKIVR YKKEALREVK VLSDLNHCNI VRYYICWIED 60

SAPQWDGSTD SSSSAQSSSD SPVKYLYIHM ELCDTKTLRA WIDEKNMQDP KKPCKRREEG 120

LGVALQIVNG VEHIHSKTLI HRDLKPANIL FDRNGMVKIG DFGLVTAEIE DDAENQKERS 180

GFKGTPSYMA PEQKRQTVYN NKVDIFALGL IYFELLWNFP TFHERNENIA SAER 234

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Equus caballus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Loxodonta africana"; ?>Monodelphis domestica"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>