EKS-ORL-00049

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORL-00049

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/RAD53	259.1	5.0E-77	178	374	197

Status

Unreviewed

Ensembl Protein

ENSORLP00000024979

UniProt Accession

H2N0R2;

Protein Name

Protein Synonyms/Alias

Gene Name

CHEK2

Gene Synonyms/Alias

CHEK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSORLG00000020130	ENSORLP00000024979	ENSORLT00000024980

Organism

Oryzias latipes

Functional Description

Protein Length

374

Protein Sequence
(FASTA)

SQVRSQSQSQ PGSGSSSGPT SGSQSSSGSG TLSSVDTIPV TLASVPEEQE PEPQPWGRLL 60

PMAKGLRVPD CIADQYLFGR DSTCNYVLDD PEERGSRKFR IYSKKHFRIF REDSQVFVED 120

LSNNGTFVDG LLVGKNKKLP LVNNAVLSLA EQRNRVFVFI DLMSDDQSSL PKDLQEKYLL 180

TRRIGAGVCG EVRLAFERST CRKVAVKVIN KKNFQSEGTA TRNAETEIKI LQRVDHPCLI 240

KTEDFYQTED SYFIVLEMME GGELFNKVKS QQQLKESVAK LYFYQMLCAV HYLHSNGIIH 300

RDLKPENILL SSNEDVCLIK VTDFNQSRIL EEAALMRTLC GTPSYLAPEV FTHANTTGYG 360

LAVDAWSLGV LLFV 374

Nucleotide Sequence
(FASTA)

TCTCAGGTGA GGTCTCAGTC CCAGTCTCAG CCAGGGTCCG GTTCGTCCAG CGGGCCCACT 60

TCAGGCAGTC AGTCTTCCAG CGGGTCTGGG ACTCTGAGCA GCGTGGACAC CATTCCTGTC 120

ACACTCGCTT CTGTCCCGGA GGAGCAAGAA CCAGAACCAC AACCCTGGGG CCGCCTGCTG 180

CCCATGGCCA AAGGCTTGAG GGTTCCAGAC TGCATTGCGG ACCAGTACCT GTTTGGACGG 240

GATTCCACAT GTAACTACGT CCTGGATGAC CCGGAAGAGA GGGGTTCCAG AAAGTTCAGA 300

ATCTACAGCA AGAAACACTT CAGGATCTTC AGAGAGGACT CTCAGGTCTT TGTGGAAGAT 360

CTCAGTAATA ACGGTACCTT TGTGGACGGT CTTCTAGTTG GTAAAAATAA GAAACTTCCT 420

CTGGTCAACA ACGCCGTCCT GTCTCTGGCC GAACAGCGAA ACAGAGTGTT TGTTTTCATT 480

GATCTCATGT CAGACGATCA GTCCAGTCTC CCCAAAGACC TGCAGGAGAA GTATCTGCTG 540

ACTCGGCGAA TTGGCGCAGG TGTGTGTGGG GAGGTGCGGC TGGCCTTCGA GCGATCTACC 600

TGCAGGAAGG TCGCAGTCAA GGTCATCAAC AAGAAGAACT TCCAGTCAGA GGGGACTGCC 660

ACACGGAACG CAGAGACAGA AATCAAGATT CTGCAGAGGG TCGACCACCC TTGTCTAATA 720

AAGACGGAGG ACTTCTACCA GACAGAGGAC AGTTACTTCA TCGTCCTCGA GATGATGGAG 780

GGGGGCGAGC TCTTCAATAA AGTCAAGTCT CAGCAGCAGC TCAAGGAATC TGTGGCCAAA 840

CTCTACTTCT ACCAGATGCT CTGCGCCGTC CACTACCTCC ACAGTAACGG GATCATCCAC 900

AGAGACCTGA AGCCGGAGAA CATCCTGCTG TCCTCCAACG AAGACGTATG CCTCATCAAG 960

GTGACGGACT TTAACCAGTC CAGGATCCTG GAAGAGGCTG CCCTGATGCG GACTCTGTGT 1020

GGGACTCCAT CCTACCTGGC TCCTGAGGTC TTCACCCACG CCAACACCAC CGGCTATGGC 1080

CTGGCTGTGG ACGCCTGGAG CCTCGGGGTC CTGCTCTTTG TC 1122

Domain Profile

S: 1     yilskelGkGafgkvklayekktgkkvavkilskrksirssreikkakeveeeveilkkl  60

         y+l +++G+G +g+v+la+e++t++kvavk+++k++    ++e + +++ e+e++il+++

Q: 178   YLLTRRIGAGVCGEVRLAFERSTCRKVAVKVINKKN---FQSEGTATRNAETEIKILQRV  234

         78999*****************************99...66677888999**********

S: 61    shPnivklkdvfeeeeskylvlelvegGelldkvvakkllkedlskllfkqlltavkylh  120

         +hP+++k +d++++e+s+++vle++egGel++kv ++++lke+++kl+f+q+l av+ylh

Q: 235   DHPCLIKTEDFYQTEDSYFIVLEMMEGGELFNKVKSQQQLKESVAKLYFYQMLCAVHYLH  294

         ************************************************************

S: 121   ekgiihrDlkPeniLlsekeedvlvkitDfGlakvlgevslmktlCGtpsyvaPevlvkk  180

         ++giihrDlkPeniLls++e+ +l+k+tDf ++++l+e  lm+tlCGtpsy+aPev ++

Q: 295   SNGIIHRDLKPENILLSSNEDVCLIKVTDFNQSRILEEAALMRTLCGTPSYLAPEVFTHA  354

         ************************************************************

S: 181   graeytskvDiWslGvvlfv  200

         ++++y  +vD WslGv+lfv

Q: 355   NTTGYGLAVDAWSLGVLLFV  374

         *******************8

Domain Sequence
(FASTA)

YLLTRRIGAG VCGEVRLAFE RSTCRKVAVK VINKKNFQSE GTATRNAETE IKILQRVDHP 60

CLIKTEDFYQ TEDSYFIVLE MMEGGELFNK VKSQQQLKES VAKLYFYQML CAVHYLHSNG 120

IIHRDLKPEN ILLSSNEDVC LIKVTDFNQS RILEEAALMR TLCGTPSYLA PEVFTHANTT 180

GYGLAVDAWS LGVLLFV 197

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>