EKS-ORL-00485

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORL-00485

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/DAPK	217.3	2.7E-64	1	130	130

Status

Unreviewed

Ensembl Protein

ENSORLP00000025759

UniProt Accession

H2N2S0;

Protein Name

Protein Synonyms/Alias

Gene Name

DAPK1

Gene Synonyms/Alias

DAPK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSORLG00000020799	ENSORLP00000025759	ENSORLT00000025760

Organism

Oryzias latipes

Functional Description

Protein Length

1317

Protein Sequence
(FASTA)

MLLNRSAPHP RIKIIDFGLA HKIDFGNDFK NIFGTPEFVA PEVVNYEPLG LEADMWSVGV 60

ITYILLSGAS PFLGDNKQET LGNVSAVDFT FDEEFFSSTS ALAKDFISRL LVKDPKKRMT 120

IQDSLQHPWI KPKDTQQALS RKESAVNMEK FKKFAARRKW KQSVRLISLC NRLSRSFLSR 180

SNMSVARSDD TLDEEDSFVM KAIIHAINDD NVPGLQHLLG SLNSYDINQP NKPTGKCPVD 240

GVAPCRSVRV LELGFFGGGV VMDLQSGANA VYYAARHGHV ETLRFLHEKK CPLNVQDKSG 300

ETALHVAARY GNVDVVSYLC TIQADPNLAD REQEIPLHCA AWHGYSAVAR ALCQAGCDVN 360

ATNREGESPL LTASARGFVD IVECLVEHRA DLQATDKDGH TALHLAVRRC QVDVVRCLLK 420

HNCQQDQQDR HGNTALHIAC KDGNLPIVIA ICGAKANLDL PNKHGRTPLH LAAKNGSLEV 480

VRHLCLAGAN IDAVTNDGKT AEDLASADRH EPIVSLLSKL KKDNLKLSFI QQLRPTQSVQ 540

PRIKLKLFGH SGAGKSTLLE SLKCGILRSF FRRRRPRGNS TTRHPNSPVS SKPAVSVSIS 600

NLYPGCENVS VRSRSMMFEP SLTKGVLEVF SPVHSGLSTA DEQATKAIDI QHANIHGVGD 660

FSVWEFSGNP VYHCSYDYFA ADDITAIHLV LFSLEEPYET QLGHITYWLN QLKALTPPQD 720

SIVFGGRIPQ PLAAVLVATH ADLAGVPRAF SGEFSYDKER ALLKEVRNRF GNDLQISDRL 780

FVMDAGASNS RDVKLLRSHL QELRAAVISV SSRFVIDAFV SLPVVASSKR CSPVTPLSER 840

LLAALPAWRK LNGPNQLMSL QQFVSDVQDN INPLVSQDHL RSVAQQLHSM GEISIMQSET 900

VQDILLLEPR WLCTSVLGKL LSVEAPKAIH HYRGRYRLEE VQALAPESDV EELLQILDAM 960

DICSRDATNP TMVDVPALIK TNGLHRSWTE DEDEDSLIYG GVRLVPVEHL TAFPCGLFHK 1020

LQVNLCRWSH QQRPEEAGGE DSDGDIHLWT NGAKVSQSGV EAMVLLVNHG QGVEIRVRGH 1080

DSDRAKSYTL LDTICSITES LLASTLPGLL TARYYLSPQQ LREHHAPIMI YQPKDFIRAQ 1140

VQRESSLTNT MGGYRESFSS ILAFGCAEIY QQGILGTGVP VSELPLLARR KLCRMLDPPD 1200

ALGKDWCLLA MNLGLTELVA KYSSATPNGA PHPEAPELQP SPTAALLQEW SRHRESTVGV 1260

LMTKLRELGR RDAADFLLKA SPVFKVNVEA VGGAQNGYLP TCNGGTSYNS ISSVISR 1317

Nucleotide Sequence
(FASTA)

ATGCTGCTGA ACCGCTCGGC GCCTCACCCG CGCATCAAGA TCATCGACTT CGGATTGGCC 60

CACAAAATCG ACTTTGGCAA CGATTTTAAA AACATCTTTG GAACTCCGGA GTTTGTCGCT 120

CCAGAAGTGG TGAACTACGA GCCTTTGGGC CTGGAGGCAG ACATGTGGAG TGTCGGCGTG 180

ATAACATACA TCCTGCTCAG TGGCGCTTCT CCGTTTCTGG GCGACAACAA GCAGGAGACG 240

CTGGGCAACG TGTCGGCGGT GGACTTCACC TTCGACGAGG AGTTCTTCAG CAGCACCAGC 300

GCGCTGGCCA AAGACTTCAT CTCCAGACTT CTGGTCAAAG ATCCAAAGAA GAGGATGACG 360

ATCCAGGACA GCCTCCAGCA CCCCTGGATC AAGCCAAAAG ACACGCAGCA GGCGCTGAGC 420

AGGAAGGAGT CGGCCGTCAA CATGGAGAAG TTCAAGAAGT TTGCAGCACG AAGAAAGTGG 480

AAGCAATCCG TCCGACTCAT CTCCTTATGT AACCGCCTGT CCCGCTCCTT CCTGTCCAGA 540

AGCAACATGA GCGTGGCGCG CAGCGACGAC ACGCTGGATG AGGAGGACTC CTTTGTGATG 600

AAGGCCATCA TCCATGCCAT CAACGATGAC AACGTGCCCG GCCTGCAGCA TCTGCTCGGC 660

TCATTAAACA GCTACGACAT CAACCAACCC AACAAGCCCA CAGGGAAATG TCCAGTTGAT 720

GGCGTCGCCC CCTGCAGGTC AGTGCGTGTT CTGGAGTTGG GTTTTTTTGG AGGGGGGGTT 780

GTCATGGACC TTCAGAGCGG AGCCAACGCC GTCTACTATG CGGCGAGGCA CGGCCACGTG 840

GAGACCCTGA GATTCCTGCA CGAGAAGAAA TGCCCCCTGA ACGTCCAAGA CAAGTCGGGG 900

GAGACCGCGC TCCACGTGGC CGCTCGCTAT GGAAACGTGG ACGTGGTTAG CTACCTGTGC 960

ACCATCCAGG CAGACCCAAA CCTGGCCGAC AGAGAGCAGG AGATTCCTCT GCACTGCGCC 1020

GCCTGGCACG GTTACTCCGC CGTGGCCAGG GCCCTCTGCC AGGCAGGCTG CGACGTGAAC 1080

GCCACCAACC GCGAAGGAGA GAGCCCGCTG CTGACTGCAT CTGCTCGGGG CTTCGTGGAC 1140

ATCGTGGAGT GTTTGGTGGA GCACCGAGCC GACCTACAGG CAACCGACAA GGATGGCCAC 1200

ACCGCTCTGC ACCTGGCTGT CCGCAGATGT CAGGTGGATG TCGTCCGATG CCTCCTCAAA 1260

CACAACTGCC AGCAGGACCA GCAGGATCGC CATGGAAACA CTGCGCTACA CATCGCCTGC 1320

AAAGATGGCA ATCTGCCCAT CGTCATAGCG ATATGCGGCG CCAAGGCCAA CCTCGACCTG 1380

CCCAACAAGC ACGGCAGGAC TCCTCTCCAC CTGGCGGCTA AAAACGGGAG CCTGGAGGTG 1440

GTCCGGCATC TCTGCCTGGC CGGCGCCAAC ATCGACGCCG TCACCAACGA CGGAAAGACG 1500

GCCGAGGATT TGGCCTCAGC TGATCGACAC GAGCCCATCG TTTCCCTGCT GTCAAAGCTT 1560

AAGAAGGACA ACCTCAAGCT GAGCTTCATC CAGCAGCTGC GGCCCACCCA GAGCGTCCAG 1620

CCCAGAATCA AACTGAAGCT GTTCGGGCAC TCGGGGGCCG GGAAGAGCAC GCTGCTGGAG 1680

TCTCTGAAAT GCGGCATCCT GCGCAGCTTC TTCAGGAGGA GGCGACCGCG CGGGAACAGC 1740

ACAACCCGCC ACCCCAACTC CCCCGTCAGC TCCAAGCCTG CAGTGTCGGT GAGCATCTCC 1800

AACTTGTATC CGGGCTGCGA GAACGTGAGC GTCCGCAGTC GCAGCATGAT GTTTGAGCCC 1860

AGCCTGACCA AAGGCGTCCT GGAGGTCTTC TCTCCCGTCC ACAGCGGCCT GTCCACGGCC 1920

GACGAACAGG CCACCAAAGC CATCGACATC CAGCACGCCA ACATTCACGG CGTGGGGGAT 1980

TTCAGCGTTT GGGAGTTTTC GGGAAACCCC GTGTACCACT GCTCCTACGA CTACTTCGCC 2040

GCTGATGACA TCACGGCGAT CCACCTGGTC CTGTTCAGCC TGGAGGAGCC GTACGAGACG 2100

CAGCTGGGCC ACATCACGTA CTGGCTGAAC CAGCTGAAGG CGCTGACGCC GCCACAGGAC 2160

AGCATCGTCT TCGGAGGACG GATCCCGCAG CCGCTGGCCG CCGTCCTGGT GGCGACGCAT 2220

GCGGACCTCG CCGGCGTTCC CAGGGCTTTC TCCGGAGAGT TCAGCTACGA CAAGGAGCGG 2280

GCGCTGCTGA AGGAAGTCAG GAACAGGTTC GGGAACGACC TGCAGATCAG TGACAGGCTG 2340

TTTGTGATGG ACGCCGGCGC CTCCAACTCC AGAGACGTGA AGCTGCTGAG GAGTCACCTG 2400

CAGGAGCTCC GCGCCGCCGT CATCTCTGTG AGCTCACGTT TTGTGATCGA TGCTTTTGTC 2460

AGTTTACCTG TTGTTGCATC TTCAAAAAGG TGCAGTCCGG TGACGCCGCT CTCGGAGCGT 2520

CTGCTCGCCG CCCTGCCGGC CTGGAGGAAG CTGAACGGAC CCAACCAGCT CATGTCGCTG 2580

CAGCAGTTCG TCAGCGACGT CCAGGACAAC ATCAACCCAC TGGTCAGCCA GGACCACCTC 2640

CGCTCGGTGG CCCAGCAGCT GCACAGCATG GGGGAGATCA GCATCATGCA GAGCGAAACG 2700

GTGCAGGACA TCCTCCTGCT GGAGCCGCGC TGGCTGTGCA CCAGCGTCCT GGGGAAGCTG 2760

CTCTCTGTGG AGGCCCCCAA AGCCATCCAC CACTACCGGG GGCGCTACCG TCTGGAGGAG 2820

GTGCAGGCTC TGGCTCCTGA GAGCGACGTG GAGGAGCTGC TGCAGATCCT GGACGCCATG 2880

GACATCTGCT CCCGCGACGC CACCAACCCG ACCATGGTGG ACGTCCCCGC CCTCATCAAG 2940

ACCAACGGGC TTCACCGCTC CTGGACCGAA GACGAGGACG AGGACTCCCT GATCTACGGG 3000

GGGGTCCGGC TGGTTCCTGT CGAGCACCTC ACTGCCTTCC CCTGCGGCCT TTTCCACAAG 3060

CTGCAGGTCA ACCTGTGCCG CTGGAGCCAC CAGCAGAGGC CCGAGGAGGC CGGCGGCGAG 3120

GATTCGGATG GAGACATCCA CCTGTGGACC AACGGAGCCA AAGTCAGCCA GTCGGGGGTG 3180

GAGGCCATGG TGCTGCTGGT CAACCACGGG CAGGGCGTGG AGATCCGGGT ACGCGGACAC 3240

GACTCTGACC GCGCCAAGAG CTACACGCTG CTGGACACCA TCTGCAGCAT CACAGAGAGC 3300

CTGCTGGCCT CCACCCTCCC CGGCCTGCTC ACCGCCAGGT ACTACCTGAG CCCCCAGCAG 3360

CTGCGCGAGC ACCACGCCCC CATCATGATC TACCAACCAA AAGACTTCAT CCGCGCTCAG 3420

GTGCAGCGCG AGAGCTCCCT CACCAACACC ATGGGGGGCT ACCGCGAGAG CTTCAGCAGC 3480

ATCCTGGCCT TTGGCTGCGC CGAAATCTAC CAGCAGGGGA TTCTGGGAAC CGGAGTCCCC 3540

GTCTCAGAGC TGCCGCTGCT GGCTCGCCGG AAACTGTGCC GCATGCTGGA CCCCCCCGAC 3600

GCCCTGGGGA AGGACTGGTG CCTTCTGGCT ATGAACCTCG GCCTCACCGA ATTAGTTGCC 3660

AAATACAGCA GTGCGACTCC GAACGGCGCC CCCCACCCGG AGGCCCCGGA ACTGCAGCCC 3720

AGCCCCACGG CGGCGCTGCT GCAGGAGTGG AGCCGGCACA GGGAGAGCAC GGTGGGGGTG 3780

CTCATGACCA AACTGAGGGA GCTGGGCCGC AGGGATGCCG CCGACTTCCT CCTGAAGGCC 3840

TCCCCCGTTT TTAAGGTCAA CGTGGAGGCG GTGGGCGGGG CCCAGAACGG CTACCTGCCC 3900

ACCTGCAACG GAGGGACATC CTACAACTCG ATAAGCTCCG TCATTTCCCG CTGA 3954

Domain Profile

S: 135   llldkkvpkgdiklidfGlsrkieegaelkeilGtPefvaPeivnyeplsletdmwsiGv  194

         +ll+++ p+++ik+idfGl++ki+ g+++k+i+GtPefvaPe+vnyepl+le+dmws+Gv

Q: 1     MLLNRSAPHPRIKIIDFGLAHKIDFGNDFKNIFGTPEFVAPEVVNYEPLGLEADMWSVGV  60

         7999999*****************************************************

S: 195   ityillsgasPflGdtkqetllnisavnldfseelfssvselakdfirrllvkdpekrlt  254

         ityillsgasPflGd+kqetl n+sav+++f+ee+fss+s lakdfi rllvkdp+kr+t

Q: 61    ITYILLSGASPFLGDNKQETLGNVSAVDFTFDEEFFSSTSALAKDFISRLLVKDPKKRMT  120

         ************************************************************

S: 255   ieeclehswl  264

         i+++l+h+w+

Q: 121   IQDSLQHPWI  130

         *********8

Domain Sequence
(FASTA)

MLLNRSAPHP RIKIIDFGLA HKIDFGNDFK NIFGTPEFVA PEVVNYEPLG LEADMWSVGV 60

ITYILLSGAS PFLGDNKQET LGNVSAVDFT FDEEFFSSTS ALAKDFISRL LVKDPKKRMT 120

IQDSLQHPWI 130

Keyword

ANK repeat; Complete proteome; Reference proteome; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity
GO:0007165	; P:signal transduction

KEGG

InterPros

IPR002110	; Ankyrin_rpt.
IPR020683	; Ankyrin_rpt-contain_dom.
IPR000488	; Death.
IPR020676	; Death-assoc_prot_kinase.
IPR011029	; DEATH-like.
IPR011009	; Kinase-like_dom.
IPR020675	; Myosin_light_ch_kinase-rel.
IPR000719	; Prot_kinase_cat_dom.

Pfam

PF12796	; Ank_2; 3.
PF00531	; Death; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00248	; ANK; 8.
SM00005	; DEATH; 1.

Prosites

PS50297	; ANK_REP_REGION; 1.
PS50088	; ANK_REPEAT; 7.
PS50017	; DEATH_DOMAIN; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

PR01415

; ANKYRIN.

Created Date

20-Feb-2013