EKS-PRC-00080

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PRC-00080

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/MLK	270.7	9.6E-81	128	349	222

Status

Unreviewed

Ensembl Protein

ENSPCAP00000004928

Gene Name

MAP3K12

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPCAG00000005253	ENSPCAP00000004928	ENSPCAT00000005260

Organism

Procavia capensis

Protein Length

844

Protein Sequence
(FASTA)

MACLHETRTP SPSFGGFVST LSEASMRKLD PDTSDCTPEK DLTPTHVLQL HEQEAGGPGG 60

AAGSPETRAS RVRADEVRLQ CQSGTGFLEG LFGCLRPVWT MIGKAYSTEH KQQQEDLWEV 120

PFEEILDLQW VGSGAQGAVF LGRFHGEEVA VKKVRDLKET DIKHLRKLKH PNIITFKGVC 180

TQAPCYCILM EFCAQGQLYE VLRAGRPVTP SLLVDWSMGI AGGMNYLHLH KIIHRDLKSP 240

FGTSKELSDK STKMSFAGTV AWMAPEVIRN EPVSEKVDIW SFGVVLWELL TGEIPYKDVD 300

SSAIIWGVGS NSLHLPVPSS CPDGFKILLR QCWNSKPRNR PSFRQILLHL DIASADVLST 360

PQETYFKSQA EWREEVKLHF EKIKSEGTCL HRLEEELVMR RREELRHALD IREHYERKLE 420

RANNLYMELN ALMLQLELKE RELLRREQAL ERRCPGLLKS HPSRSLLHGN TVEKLIKKRN 480

VPQKLSPHSK RPDILKTESL LPKLDAALSG VGLPGCPKGP PSPGRSRRGK TRHRKASTKG 540

SCGDLPGLRA AVPAPEPGPG SPGGLGGGPS GWEACPPALR GLHHDLLLRK MSSSSPDLLS 600

AALGARGRGA TGGAGDAGSP PPARGDTPPS EGSAPGSTSP DSPGGAKGEP PPPAGPGDGV 660

GLLGTGKEGT AGRGGSRAGA QHLTPAALLY RAAVTRSQKR GISSEEEEGE VDSEVELTAS 720

QRWPQGLNMR QSLSTFSSEN PSDGEEGTAS EPSPSGTPEV GSTNTDERPD ERSDDMCSQG 780

SEIPLDPPVS VIVPGPEPSS LPIPQQDLLR EQGPPNPEDS DCDSTELDNS NNGDTLRPPA 840

SLPP 844

Nucleotide Sequence
(FASTA)

ATGGCCTGCC TCCATGAGAC TCGCACCCCT TCCCCTTCCT TTGGGGGCTT TGTGTCAACC 60

CTCAGCGAGG CGTCCATGCG CAAGCTTGAC CCAGACACTT CTGACTGCAC CCCTGAGAAG 120

GATCTGACGC CAACCCATGT CCTACAGCTA CATGAGCAGG AAGCAGGGGG TCCAGGGGGA 180

GCAGCTGGGT CCCCTGAGAC CCGGGCATCC CGAGTTCGAG CTGATGAAGT GCGGTTGCAG 240

TGCCAAAGTG GCACTGGCTT CCTTGAAGGC CTCTTTGGCT GCCTGCGCCC TGTCTGGACG 300

ATGATTGGCA AAGCCTACTC CACTGAACAC AAGCAGCAGC AGGAAGACCT CTGGGAGGTC 360

CCCTTTGAGG AAATCCTGGA CCTACAGTGG GTGGGCTCAG GGGCCCAGGG CGCTGTCTTC 420

CTGGGGCGAT TCCACGGGGA AGAGGTGGCT GTGAAGAAGG TGCGAGACCT CAAGGAAACC 480

GACATCAAGC ACCTCCGAAA GCTGAAGCAT CCCAACATCA TAACCTTCAA GGGTGTGTGC 540

ACTCAGGCAC CCTGCTACTG CATTCTCATG GAGTTCTGCG CCCAGGGCCA GCTGTATGAG 600

GTACTGCGGG CTGGCCGCCC CGTCACCCCC TCTTTGCTGG TTGACTGGTC CATGGGCATT 660

GCCGGTGGCA TGAACTACCT GCACCTGCAC AAGATTATCC ACAGAGACCT CAAATCCCCC 720

TTTGGCACTT CCAAGGAGCT GAGTGACAAG AGCACCAAGA TGTCCTTTGC AGGAACAGTA 780

GCATGGATGG CCCCTGAGGT GATCCGCAAT GAGCCCGTGT CTGAGAAGGT CGATATCTGG 840

TCATTTGGCG TTGTGCTGTG GGAACTGCTT ACTGGTGAGA TCCCCTACAA AGATGTGGAC 900

TCCTCAGCCA TCATCTGGGG TGTGGGAAGC AACAGTCTCC ATCTGCCTGT GCCCTCTAGC 960

TGCCCAGATG GTTTCAAAAT CCTCCTCCGC CAATGCTGGA ACAGCAAACC CCGAAATCGT 1020

CCATCATTCC GACAGATCCT GCTGCACCTG GATATCGCCT CAGCCGATGT GCTCTCCACA 1080

CCCCAGGAAA CTTACTTTAA GTCCCAGGCA GAGTGGCGGG AAGAGGTAAA GCTGCACTTT 1140

GAGAAAATTA AGTCAGAAGG GACCTGTCTA CATCGCCTAG AAGAGGAGCT GGTGATGCGA 1200

AGGAGGGAGG AACTCAGACA TGCCTTGGAC ATCAGGGAAC ACTATGAACG GAAGTTGGAG 1260

AGGGCCAACA ACCTGTACAT GGAACTTAAT GCCCTGATGT TGCAGCTGGA GCTCAAGGAA 1320

CGTGAGCTGC TCAGGCGGGA GCAAGCTTTA GAACGAAGGT GCCCAGGCCT GCTGAAGTCA 1380

CACCCTTCCC GGAGCCTCCT GCATGGGAAC ACAGTGGAGA AACTCATCAA GAAGAGGAAT 1440

GTGCCACAGA AGCTGTCACC ACATAGCAAA AGGCCAGATA TTCTCAAGAC AGAGTCTTTA 1500

CTACCTAAAT TAGACGCAGC CCTGAGTGGG GTGGGACTTC CTGGCTGTCC TAAAGGGCCC 1560

CCCTCACCAG GACGGAGTCG GCGTGGCAAG ACCCGTCACC GAAAGGCCAG CACCAAGGGC 1620

AGTTGTGGGG ACCTGCCTGG ACTTCGTGCA GCTGTGCCAG CGCCTGAGCC TGGACCAGGA 1680

AGCCCTGGGG GGCTGGGCGG GGGGCCTTCA GGCTGGGAGG CCTGCCCCCC TGCCCTCCGT 1740

GGGCTCCATC ATGATCTTCT GCTACGCAAG ATGTCTTCAT CATCCCCTGA TCTACTGTCA 1800

GCAGCACTGG GGGCCCGGGG CCGGGGAGCC ACAGGGGGAG CTGGAGATGC TGGCTCACCC 1860

CCTCCAGCCC GGGGTGACAC CCCTCCAAGT GAGGGCTCAG CTCCTGGCTC CACCAGTCCA 1920

GATTCACCTG GGGGAGCCAA AGGGGAGCCC CCTCCACCAG CTGGGCCTGG TGATGGTGTG 1980

GGGCTGCTAG GGACTGGAAA AGAAGGGACC GCGGGACGGG GAGGAAGTCG GGCTGGGGCC 2040

CAGCACTTGA CCCCAGCTGC ACTGCTGTAC AGGGCTGCTG TCACCCGAAG CCAGAAGCGA 2100

GGCATCTCAT CAGAAGAAGA GGAAGGAGAG GTGGACAGTG AAGTAGAGCT GACAGCAAGC 2160

CAGAGGTGGC CCCAGGGCCT GAACATGCGC CAGTCACTAT CTACCTTCAG TTCAGAGAAC 2220

CCATCAGATG GGGAGGAGGG CACAGCTAGT GAGCCTTCCC CCAGTGGCAC ACCCGAAGTT 2280

GGGAGTACCA ACACAGATGA GCGGCCAGAT GAGCGGTCTG ATGACATGTG CTCCCAGGGC 2340

TCAGAAATCC CACTGGACCC ACCTGTTTCA GTGATAGTCC CTGGTCCTGA ACCTAGCTCC 2400

TTGCCCATCC CACAGCAAGA CCTACTCAGA GAACAGGGCC CTCCCAATCC TGAGGATTCA 2460

GACTGTGACA GCACTGAACT GGACAATTCC AACAATGGCG ATACCTTGCG GCCTCCAGCC 2520

TCCCTCCCAC CATGA 2535

Domain Profile

S: 4     eeligsgafgkvykakwrkkevavKklreeaeekekleklereakllsklshpniiellG  63

          +++gsga+g+v+ ++++++evavKk+r+ +e+         ++k+l+kl+hpnii+++G

Q: 128   LQWVGSGAQGAVFLGRFHGEEVAVKKVRDLKET---------DIKHLRKLKHPNIITFKG  178

         689**************************9999.........******************

S: 64    vcleepnlllvmeyveggsLsnvlhekskreidlevlvswalqiArGmaYLhseapkkii  123

         vc++ p+++++me++++g+L++vl++   r ++++ lv+w++ iA Gm+YLh +   kii

Q: 179   VCTQAPCYCILMEFCAQGQLYEVLRA--GRPVTPSLLVDWSMGIAGGMNYLHLH---KII  233

         **************************..99************************...9**

S: 124   hrdLksknvLlseekktlkicdFGtarelsk.stkmsaagtlawmaPEvlkeekvseksD  182

         hrdLks+               FGt++els+ stkms+agt+awmaPEv+++e+vsek+D

Q: 234   HRDLKSP---------------FGTSKELSDkSTKMSFAGTVAWMAPEVIRNEPVSEKVD  278

         *****96...............********99****************************

S: 183   vwSygvvLWelltrevPykdlselaiaykvalkglrlpipsscpeklkkLmkecwnedpe  242

         +wS+gvvLWellt+e+Pykd+++ ai+++v++++l+lp+psscp+ +k L+++cwn++p+

Q: 279   IWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSKPR  338

         ************************************************************

S: 243   kRpsfseivks  253

         +Rpsf++i+ +

Q: 339   NRPSFRQILLH  349

         ********876

Domain Sequence
(FASTA)

LQWVGSGAQG AVFLGRFHGE EVAVKKVRDL KETDIKHLRK LKHPNIITFK GVCTQAPCYC 60

ILMEFCAQGQ LYEVLRAGRP VTPSLLVDWS MGIAGGMNYL HLHKIIHRDL KSPFGTSKEL 120

SDKSTKMSFA GTVAWMAPEV IRNEPVSEKV DIWSFGVVLW ELLTGEIPYK DVDSSAIIWG 180

VGSNSLHLPV PSSCPDGFKI LLRQCWNSKP RNRPSFRQIL LH 222

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>