EKS-PEM-00181

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PEM-00181

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/PEK	293.6	8.4E-88	105	505	401

Status

Unreviewed

Ensembl Protein

ENSPMAP00000002333

Gene Name

EIF2AK1

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPMAG00000002117	ENSPMAP00000002333	ENSPMAT00000002344

Organism

Petromyzon marinus

Protein Length

544

Protein Sequence
(FASTA)

VSNQLLLVTL LEHLCSLYER DPINKQALFH AIGAHLIKLK LVSPSSFCDE FATVRNQYSK 60

ALCDLLRSGS SHLHTEDCEN DGFASYRGQK EQAFHMHTSR YLSEFEEVCR LGRGGYGQVF 120

KVRNKLDRQL YAVKKVLIKG SGESICKKVL REVKLLAGLQ HLSIVGYHGA WLELLQPPTL 180

AAPFQPLPSA EAGCQRNVGW CPPGRFSSCH VPSLVQAHGG LNSESRDNSG HNKNSINEDS 240

GRKSEHSGSN GKPTNLRKEL YESNSKHVGS NYEHSESNSE HSENSNTSWT PGSDSKDRDL 300

HLVLYIQMQL CERSLKEWLM DRNALLQQCT GRYALVDGKQ TTRMFQQLLE GVHYIHSRGI 360

MHRDLKPRNI FLHGPDHHVR IGDFGLACQD IVYEDPRLIR AGAGVVGSAH TSGVGTTLYA 420

APEQLSGSHY DFKSDMYSVG IVLFELFQPF GTEMERVKTI QELRGGVVSS PFTAQWPVQA 480

KYIGLLTQDD PAARPNPQDI LTTDLIGNKD QVGLTLHIIC LLRRSFKDRT KVFVFLSMLL 540

NLCQ 544

Nucleotide Sequence
(FASTA)

GTGTCCAACC AGCTGCTGTT GGTCACGCTG CTGGAGCACC TATGCTCATT GTATGAGCGA 60

GATCCCATAA ACAAGCAGGC GCTCTTCCAC GCCATTGGTG CACACCTAAT CAAACTGAAG 120

CTGGTCTCTC CATCATCCTT CTGCGATGAA TTTGCCACGG TGCGGAATCA GTACAGCAAG 180

GCTTTGTGTG ACCTGCTGCG CTCTGGATCC AGCCACCTGC ACACCGAGGA TTGTGAAAAC 240

GATGGCTTCG CATCTTATAG AGGGCAGAAA GAGCAAGCTT TCCACATGCA CACATCACGT 300

TACTTGAGCG AGTTTGAAGA GGTTTGCCGG CTTGGTCGCG GGGGCTATGG TCAGGTCTTC 360

AAGGTGCGCA ACAAGTTGGA TAGACAGCTG TACGCTGTCA AAAAGGTGCT CATCAAGGGA 420

TCCGGCGAAA GTATTTGCAA AAAGGTGCTG CGGGAGGTAA AGTTGCTGGC CGGGCTGCAG 480

CACCTGAGCA TTGTGGGCTA CCACGGCGCA TGGTTGGAGT TGCTCCAACC TCCTACTCTA 540

GCAGCACCAT TTCAACCCCT GCCAAGTGCA GAGGCAGGTT GCCAGAGAAA TGTTGGCTGG 600

TGTCCACCTG GTAGATTTTC TTCATGTCAC GTGCCTTCTC TGGTCCAGGC CCATGGTGGC 660

TTAAACAGTG AGAGCCGCGA CAACAGCGGC CACAATAAGA ATAGTATAAA CGAGGATTCT 720

GGGAGAAAAA GCGAGCATTC TGGGAGCAAT GGCAAACCCA CAAACCTCAG AAAGGAATTG 780

TATGAGAGCA ACAGCAAGCA TGTTGGGAGT AATTATGAAC ATTCTGAGAG TAATAGTGAA 840

CATTCTGAAA ACAGCAACAC CAGTTGGACT CCAGGGTCTG ACAGCAAAGA TCGGGACCTT 900

CACCTCGTCC TCTACATCCA GATGCAGCTG TGTGAAAGGT CACTCAAAGA GTGGCTCATG 960

GATCGGAATG CCCTTTTACA GCAATGTACA GGGCGATACG CACTGGTGGA TGGGAAGCAG 1020

ACCACTCGAA TGTTTCAGCA ACTTCTGGAG GGAGTTCATT ACATCCACTC GAGGGGTATC 1080

ATGCACCGTG ACCTCAAGCC AAGGAATATT TTTCTCCATG GACCGGACCA CCACGTGCGC 1140

ATTGGAGACT TTGGGCTGGC TTGCCAGGAC ATTGTATATG AAGACCCCAG GCTCATACGT 1200

GCCGGTGCTG GAGTTGTCGG TAGCGCTCAC ACGTCAGGGG TGGGCACTAC CCTGTACGCG 1260

GCTCCCGAGC AGCTCTCGGG CTCCCACTAC GACTTTAAGT CGGACATGTA CAGTGTAGGG 1320

ATCGTGCTGT TCGAGCTGTT CCAACCGTTC GGAACAGAGA TGGAGCGTGT GAAGACCATC 1380

CAGGAACTTA GGGGTGGAGT TGTCTCCAGC CCTTTCACAG CACAGTGGCC CGTACAGGCC 1440

AAGTACATTG GCCTCCTGAC TCAGGATGAC CCTGCCGCGC GTCCCAACCC GCAAGACATC 1500

CTCACCACAG ACCTCATTGG TAACAAGGAC CAGGTAGGCC TTACGTTACA TATTATTTGT 1560

TTGTTAAGGA GGTCTTTTAA AGATCGTACA AAAGTGTTTG TGTTTTTGTC AATGCTTCTA 1620

AATTTATGCC AA 1632

Domain Profile

S: 1     feeikvlGkGgfgvVlkaknkldkkeyaikriklnkakke.lekverevkaLaklehpni  59

         fee++ lG+Gg+g+V+k++nkld++ ya+k++ ++   ++ ++kv+revk+La l+h +i

Q: 105   FEEVCRLGRGGYGQVFKVRNKLDRQLYAVKKVLIKGSGESiCKKVLREVKLLAGLQHLSI  164

         899*********************************99999*******************

S: 60    vrYfaawleekeesl.............................................  74

         v Y+ awle  + +

Q: 165   VGYHGAWLELLQPPTlaapfqplpsaeagcqrnvgwcppgrfsschvpslvqahgglnse  224

         *********9999999********************************************

S: 75    ......................................tdsseveaeaeleesesseesd  96

                                               ++s++v +++e +es+s+++++

Q: 225   srdnsghnknsinedsgrksehsgsngkptnlrkelyeSNSKHVGSNYEHSESNSEHSEN  284

         **************9999999999999999999999963366666666555555554444

S: 97    tk................llyiqmelceketLkdwiderkllesrselvm.........r  131

         ++                +lyiqm+lce ++Lk+w+ +r+ l +++  +          r

Q: 285   SNtswtpgsdskdrdlhlVLYIQMQLCE-RSLKEWLMDRNALLQQCTGRYalvdgkqttR  343

         445688899999****************.9******99995555555544456777777*

S: 132   lfkqllegleylHskgliHrdLkpsniFld.sddqvKigDFgLatalaealked.vkqda  189

         +f+qlleg++y+Hs+g++HrdLkp+niFl+  d++v+igDFgLa++++  +  + ++  a

Q: 344   MFQQLLEGVHYIHSRGIMHRDLKPRNIFLHgPDHHVRIGDFGLACQDIVYEDPRlIRAGA  403

         ******************************9999************88655543144555

S: 190   qskeakhtgqvgtklymsPeqleksqYnkkvDifsLGlilfeLlypfstemervetltel  249

             + ht+ vgt+ly++Peql++s+Y+ k+D++s+G++lfeL++pf temerv+t++el

Q: 404   GVVGSAHTSGVGTTLYAAPEQLSGSHYDFKSDMYSVGIVLFELFQPFGTEMERVKTIQEL  463

         55558*******************************************************

S: 250   rdgkipedfddkvpkekkllqkllsrdpkeRpsasellksel  291

         r g +++ f+++ p+++k++  l++ dp+ Rp+++++l ++l

Q: 464   RGGVVSSPFTAQWPVQAKYIGLLTQDDPAARPNPQDILTTDL  505

         **************************************9876

Domain Sequence
(FASTA)

FEEVCRLGRG GYGQVFKVRN KLDRQLYAVK KVLIKGSGES ICKKVLREVK LLAGLQHLSI 60

VGYHGAWLEL LQPPTLAAPF QPLPSAEAGC QRNVGWCPPG RFSSCHVPSL VQAHGGLNSE 120

SRDNSGHNKN SINEDSGRKS EHSGSNGKPT NLRKELYESN SKHVGSNYEH SESNSEHSEN 180

SNTSWTPGSD SKDRDLHLVL YIQMQLCERS LKEWLMDRNA LLQQCTGRYA LVDGKQTTRM 240

FQQLLEGVHY IHSRGIMHRD LKPRNIFLHG PDHHVRIGDF GLACQDIVYE DPRLIRAGAG 300

VVGSAHTSGV GTTLYAAPEQ LSGSHYDFKS DMYSVGIVLF ELFQPFGTEM ERVKTIQELR 360

GGVVSSPFTA QWPVQAKYIG LLTQDDPAAR PNPQDILTTD L 401

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xiphophorus maculatus"; ?>