EKS-PEM-00141

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PEM-00141

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/DYRK	436.9	2.6E-131	192	520	329

Status

Unreviewed

Ensembl Protein

ENSPMAP00000002996

Gene Name

HIPK3

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPMAG00000002739	ENSPMAP00000002996	ENSPMAT00000003011

Organism

Petromyzon marinus

Protein Length

1127

Protein Sequence
(FASTA)

VDPHSQGMAS QVQVFSPHLG AFFSAKKLKV ESSGYGCHDG AAAYRHTLPS GPLALLLLLL 60

LLPPPLPATP ARRSFHTTAE ARGHSRAASV GGAAVPGAAG GGPTHSLMRR STVSLLDTYT 120

RCGLKRKSEE LDACAAAAAT AAAPPLLQSN AGGGGTVPGG GAGGGGKAGG PAADGDYTLV 180

QHEVLRSMTN SYEVLEFLGR GTFGQVVKCW KRGTSEIVAI KILKNHPSYA RQGQVEVGIL 240

ARLSSESADD YNFVRAHECF QHKSHTCLVF EMLEQNLYDF LKQNNFSPLP LKYIRPVLQQ 300

VASALMKLKS LGLIHADLKP ENIMLVDPVR QPYRVKVIDF GSASHVSKAV CSTYLQSRYY 360

RAPEIILGLP FCEAIDMWSL GCVIAELFLG WPLYPGASEY DQIRYISATQ GLPPEQLLSA 420

GTKTGRFFQR ETGAGYPLWR IKSPEEHEAE TGIKSKEARK YMFNCLEDMG QVNPASDLEG 480

SDVLAEKADR RQFIELLRRM LTMDADKRIS PLETLAHPFV TMTHLVDFPR TNHIKSCFQN 540

MEVCKRRLQL YELGPSKAPF LAQVAQGPST NLTVTFNTMH TQAAGPPSAG GATLSLLSPE 600

VGSLLGYPSA LYQPVARGGV TLGPAGPPQY PPRHDTYQQT LIVCPPPTFT AGLQASPSKP 660

PGFSVVSQAQ PLTLAPQGGG LLAQGGLLAQ AWPSGAQQIL LPTWQQLAAP PPPPVLAESL 720

TDWRAPHAHR TSYGTLVQQP PILAGRVTLP GGPPVGVAVG VGLHSQLHRH TSSQTGGEHK 780

RSNKENCSPP TPPLAPSGSA ATALLPHCTV VRGSPPSQGS SSGAVWCAPP GAHRGAHTIV 840

ITDTPSPSTS VITISSDTDT EREERTCSQA NGHQQTPIGC VTVCDSPESG SPSPAGRPSP 900

AGDWGYRKLA PPSAMVQPLQ HQHTDKITLA LGPNLLQVAT CFQDVARESS RNEPHRAMIG 960

LSSPARLPGA GQHGLPHRGS HNQHQQQPLN LSQVRAVTKR SISARRQQAY IAPYCFPHAS 1020

PPHALHTHLA APPPPPAQTH LYTYAAHLVG PPHPSAGGPA APPQGRGCAG AGGGFPGALV 1080

AIGHRVLPSP HFAALPVRAP YLGASQGSAI YTGYPLSPGK IGTFTYM 1127

Nucleotide Sequence
(FASTA)

GTGGATCCCC ACTCCCAAGG CATGGCTTCC CAGGTGCAGG TGTTCTCCCC ACACTTGGGA 60

GCCTTCTTCA GCGCCAAGAA GCTCAAGGTG GAGTCCAGCG GCTACGGCTG CCATGACGGC 120

GCCGCTGCCT ACCGCCACAC CCTGCCTTCC GGCCCGTTGG CGCTGCTGCT GCTGCTGCTG 180

CTGCTGCCGC CGCCACTGCC AGCGACCCCG GCTCGTCGCT CCTTCCACAC GACGGCGGAG 240

GCTCGGGGCC ACTCGCGGGC GGCATCGGTG GGTGGGGCAG CCGTGCCGGG AGCTGCGGGT 300

GGGGGCCCCA CACACAGCCT GATGCGGCGC AGCACAGTCA GCCTGCTGGA CACCTACACG 360

CGCTGCGGGC TCAAGCGTAA GAGTGAGGAG CTGGACGCTT GTGCTGCTGC CGCCGCCACT 420

GCTGCTGCGC CACCACTGCT GCAGAGCAAT GCAGGTGGAG GTGGCACGGT GCCCGGTGGT 480

GGCGCGGGTG GCGGAGGGAA GGCGGGGGGG CCAGCCGCGG ATGGGGACTA CACACTGGTG 540

CAACACGAGG TCCTGCGCTC CATGACCAAC AGCTATGAGG TGCTGGAGTT TCTGGGGCGC 600

GGTACGTTCG GCCAGGTGGT GAAATGCTGG AAGCGCGGCA CCAGCGAGAT CGTGGCCATC 660

AAGATCCTGA AGAACCACCC GTCTTACGCT CGACAGGGCC AGGTGGAGGT GGGCATCCTC 720

GCGCGCCTGA GCTCGGAAAG CGCCGATGAC TACAACTTTG TGCGCGCGCA CGAGTGTTTC 780

CAGCATAAGA GCCACACGTG CCTCGTCTTC GAGATGCTGG AGCAGAACCT CTACGACTTC 840

CTGAAGCAGA ACAACTTCAG CCCGCTGCCC CTCAAGTACA TCCGACCCGT GCTGCAGCAG 900

GTGGCCAGCG CACTCATGAA GCTCAAGAGC CTGGGTCTCA TTCACGCCGA CCTGAAGCCA 960

GAGAACATCA TGCTGGTGGA CCCCGTGCGT CAGCCCTACC GTGTCAAGGT CATTGACTTC 1020

GGCTCGGCCA GCCACGTCTC CAAGGCCGTG TGCTCCACCT ACCTGCAGTC TCGTTACTAC 1080

AGGGCTCCGG AAATCATTCT GGGTCTGCCA TTCTGCGAGG CCATCGACAT GTGGTCGCTT 1140

GGCTGTGTCA TAGCGGAGCT TTTCCTGGGC TGGCCTCTCT ACCCTGGTGC CTCTGAGTAT 1200

GACCAGATCC GCTACATTTC TGCAACTCAA GGCCTCCCAC CGGAGCAGTT GCTCAGTGCC 1260

GGCACCAAGA CGGGGCGGTT CTTCCAGCGC GAGACAGGAG CAGGATACCC TCTGTGGAGG 1320

ATCAAGTCCC CAGAGGAGCA CGAGGCAGAA ACGGGAATCA AATCTAAAGA GGCAAGGAAG 1380

TACATGTTTA ATTGCCTGGA GGACATGGGC CAGGTGAACC CAGCGTCGGA CCTGGAGGGC 1440

AGCGACGTGC TGGCGGAGAA AGCCGACCGG CGCCAGTTCA TCGAGCTGCT GCGCCGCATG 1500

CTGACGATGG ACGCCGACAA GCGCATATCA CCGCTCGAGA CACTGGCGCA TCCCTTCGTC 1560

ACCATGACCC ACCTTGTCGA CTTCCCCCGC ACCAACCACA TCAAGTCGTG CTTTCAGAAC 1620

ATGGAGGTGT GTAAGCGGCG GCTGCAACTG TACGAGCTGG GGCCCAGCAA GGCCCCATTC 1680

CTCGCGCAGG TGGCACAGGG ACCGTCGACA AACCTCACGG TCACTTTCAA TACCATGCAC 1740

ACACAGGCGG CCGGGCCTCC GTCAGCTGGT GGGGCCACGT TGTCCTTGCT GAGCCCGGAG 1800

GTCGGCTCCC TGCTGGGCTA CCCGTCCGCC CTCTATCAGC CGGTGGCACG GGGCGGTGTG 1860

ACGCTGGGCC CCGCAGGGCC CCCTCAGTAC CCACCGCGCC ACGACACCTA CCAGCAGACA 1920

CTCATTGTGT GTCCGCCTCC TACCTTCACT GCAGGCCTGC AGGCCTCCCC CAGCAAGCCG 1980

CCCGGCTTCT CGGTCGTGAG CCAAGCCCAG CCGCTCACGC TGGCGCCCCA GGGAGGGGGC 2040

CTCTTGGCCC AGGGAGGGCT GTTGGCACAG GCATGGCCCA GCGGAGCCCA GCAGATTCTC 2100

CTGCCAACCT GGCAGCAGTT GGCCGCTCCC CCACCTCCTC CGGTTCTCGC CGAGTCCCTC 2160

ACCGACTGGA GGGCACCTCA TGCGCATCGA ACGTCGTACG GGACGCTGGT GCAGCAGCCG 2220

CCGATCCTGG CAGGGCGCGT CACGCTCCCT GGAGGACCCC CCGTCGGTGT GGCTGTTGGG 2280

GTCGGGTTGC ACTCACAGCT GCACCGACAC ACGTCCAGCC AAACCGGGGG GGAGCACAAG 2340

CGGAGCAACA AGGAGAACTG CTCCCCGCCG ACGCCCCCTC TGGCCCCCTC GGGATCCGCC 2400

GCCACCGCGC TGCTCCCGCA CTGCACGGTG GTGCGCGGGA GCCCCCCGTC CCAGGGCAGC 2460

AGCTCAGGCG CAGTGTGGTG CGCCCCGCCC GGGGCCCACC GGGGTGCCCA CACCATCGTC 2520

ATCACGGACA CGCCCAGCCC CAGCACCAGC GTCATCACCA TCAGCAGCGA CACGGACACG 2580

GAAAGGGAGG AGCGCACGTG CAGCCAAGCT AACGGCCACC AGCAGACCCC TATCGGCTGT 2640

GTGACGGTGT GCGACTCCCC CGAGAGTGGC TCCCCATCAC CCGCAGGCCG TCCGTCGCCC 2700

GCAGGGGACT GGGGGTACAG GAAGCTAGCG CCCCCCTCAG CCATGGTGCA GCCCCTGCAG 2760

CACCAGCACA CAGACAAGAT CACTCTAGCA CTTGGCCCCA ACCTTCTTCA AGTGGCGACC 2820

TGCTTCCAAG ATGTGGCTCG TGAGAGCTCC CGGAATGAAC CCCACCGAGC TATGATCGGT 2880

CTTAGCTCGC CTGCACGTCT GCCGGGGGCT GGGCAGCATG GCCTTCCTCA CCGGGGAAGC 2940

CACAATCAGC ACCAGCAGCA GCCCTTAAAC CTCAGCCAGG TGAGAGCCGT AACAAAGAGA 3000

AGCATAAGCG CCCGTCGCCA GCAGGCGTAC ATCGCTCCCT ACTGCTTCCC GCACGCGAGC 3060

CCCCCGCACG CGCTGCACAC CCACCTGGCA GCACCTCCCC CACCGCCCGC ACAGACGCAC 3120

CTCTACACCT ACGCGGCCCA CCTGGTGGGG CCCCCGCATC CTTCCGCCGG GGGCCCTGCC 3180

GCACCCCCCC AGGGTCGTGG CTGCGCTGGC GCTGGCGGTG GTTTCCCGGG GGCCCTGGTG 3240

GCCATCGGTC ACCGCGTTCT GCCCTCGCCG CACTTTGCCG CTCTGCCAGT GAGGGCCCCG 3300

TACCTAGGCG CATCGCAAGG CTCGGCAATC TACACGGGCT ACCCGCTCAG CCCCGGCAAG 3360

ATCGGCACGT TCACCTACAT GTGA 3384

Domain Profile

S: 1     yevlevigkGsfgqVvkaldkktkeivaikiiknkkrfarqaqeEveiLeklnkkdkeek  60

         yevle++g+G+fgqVvk++++ t+eivaiki+kn++++arq+q Ev iL++l++ +++++

Q: 192   YEVLEFLGRGTFGQVVKCWKRGTSEIVAIKILKNHPSYARQGQVEVGILARLSS-ESADD  250

         9****************************************************9.999**

S: 61    ynvvrllelfvfrnhlclvfellsqnLyellkknkfsglslklvrklaqqilkaLklLke  120

         yn+vr+ e+f++++h+clvfe+l+qnLy++lk+n+fs+l+lk++r+++qq+++aL++Lk+

Q: 251   YNFVRAHECFQHKSHTCLVFEMLEQNLYDFLKQNNFSPLPLKYIRPVLQQVASALMKLKS  310

         ************************************************************

S: 121   lkiiHaDlKPeNillvekkrse..vkviDFGsssavsqkeiytyiqsrfYraPEiilglk  178

         l++iHaDlKPeNi+lv++ r++  vkviDFGs+s+vs+++++ty+qsr+YraPEiilgl+

Q: 311   LGLIHADLKPENIMLVDPVRQPyrVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLP  370

         *********************999************************************

S: 179   ydeaiDmWSlGcvlaElftGkpLfpGenevdqlalivevlglppekllekakkakkff..  236

         ++eaiDmWSlGcv+aElf+G+pL+pG++e+dq+++i+ ++glppe+ll++++k+ +ff

Q: 371   FCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISATQGLPPEQLLSAGTKTGRFFqr  430

         **********************************************************65

S: 237   .tkkeapkyilktk.........ksdrkkklvlnvkkaakkrkaplskelgealkekedk  286

          t  ++p +++k+          ks++++k+++n+ +++ ++++  + e +++l+ek+d+

Q: 431   eTGAGYPLWRIKSPeeheaetgiKSKEARKYMFNCLEDMGQVNPASDLEGSDVLAEKADR  490

         5556778888887799*****************************************999

S: 287   l.fkdllkrmleldpakRitpkealkhpfv  315

         + f++ll+rml++d++kRi+p e+l hpfv

Q: 491   RqFIELLRRMLTMDADKRISPLETLAHPFV  520

         99***************************7

Domain Sequence
(FASTA)

YEVLEFLGRG TFGQVVKCWK RGTSEIVAIK ILKNHPSYAR QGQVEVGILA RLSSESADDY 60

NFVRAHECFQ HKSHTCLVFE MLEQNLYDFL KQNNFSPLPL KYIRPVLQQV ASALMKLKSL 120

GLIHADLKPE NIMLVDPVRQ PYRVKVIDFG SASHVSKAVC STYLQSRYYR APEIILGLPF 180

CEAIDMWSLG CVIAELFLGW PLYPGASEYD QIRYISATQG LPPEQLLSAG TKTGRFFQRE 240

TGAGYPLWRI KSPEEHEAET GIKSKEARKY MFNCLEDMGQ VNPASDLEGS DVLAEKADRR 300

QFIELLRRML TMDADKRISP LETLAHPFV 329

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>