EKS-PEM-00123

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PEM-00123

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/MAPKAPK	347.2	3.2E-104	5	259	255

Status

Unreviewed

Ensembl Protein

ENSPMAP00000005429

Gene Name

MKNK1

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPMAG00000004929	ENSPMAP00000005429	ENSPMAT00000005449

Organism

Petromyzon marinus

Protein Length

372

Protein Sequence
(FASTA)

DVVVQIIEKC QGQRRDRVFR EVEMLYQCQG HRNILELVEF FEDEKAFYLV FEKMHGGSIL 60

THIQMRKHFN EKEASRVVRD IASALHFLHN KGIAHRDLKP ENILCELADQ VTPVRICDFD 120

LGSGVPVGST PISTPELATP CGSAEYMAPE VVEAFNEEEA SFYDKRCDLW SLGVITYILL 180

SGYPPFVGNC GGQCGWDSGQ PCSPCQKMLF ARIQEGHYEF PEKDWAGVSV HAKDLISKLL 240

VRNAKQRLSA AQVLDHPWLR GNALENTLLT PQLLQRKSSV TGLTQFAAEA VAFKRQISQK 300

DEHEHGHGEE GAALVDIAEF AAAAEECRPP ASQLHSMRLS PPARSRLARR RANGGRSPVK 360

QVEGEPRAAL AG 372

Nucleotide Sequence
(FASTA)

GATGTTGTGG TCCAGATCAT AGAGAAGTGT CAAGGACAGA GGCGGGACCG AGTTTTCCGC 60

GAGGTGGAAA TGCTGTACCA GTGCCAAGGC CATAGGAACA TCTTAGAGCT AGTTGAGTTC 120

TTTGAGGATG AGAAAGCATT CTACTTGGTG TTTGAGAAGA TGCATGGAGG TTCAATCCTG 180

ACTCACATCC AGATGCGGAA GCATTTCAAT GAGAAGGAAG CCAGCCGGGT TGTACGAGAT 240

ATCGCGAGCG CCCTTCACTT CCTGCACAAC AAAGGAATCG CTCACCGAGA TCTCAAGCCT 300

GAAAACATCC TGTGCGAGTT GGCCGATCAG GTGACCCCAG TGCGGATTTG TGACTTTGAT 360

CTTGGCAGCG GAGTGCCGGT CGGCAGCACG CCCATCTCCA CACCAGAGCT GGCCACACCG 420

TGCGGCTCCG CCGAGTACAT GGCCCCCGAG GTGGTCGAAG CCTTTAACGA GGAGGAGGCT 480

TCCTTCTATG ACAAACGCTG CGACCTCTGG AGCCTGGGCG TCATCACGTA CATCCTGCTC 540

AGCGGTTACC CTCCCTTTGT GGGCAACTGC GGCGGGCAGT GCGGCTGGGA CAGCGGGCAG 600

CCCTGCTCGC CTTGCCAGAA AATGCTATTT GCACGGATCC AAGAGGGTCA CTACGAGTTC 660

CCAGAGAAGG ACTGGGCGGG CGTGTCAGTC CATGCCAAGG ACTTGATCTC CAAGCTGCTG 720

GTGCGCAACG CCAAACAGAG GCTGAGTGCA GCGCAGGTGC TGGATCATCC CTGGTTGAGA 780

GGGAACGCCC TCGAGAACAC GTTGCTAACG CCGCAGCTGC TGCAGCGGAA GAGCAGCGTC 840

ACCGGCCTCA CGCAGTTTGC AGCGGAGGCC GTGGCGTTCA AGCGGCAGAT CTCGCAGAAG 900

GACGAGCACG AGCACGGGCA CGGGGAGGAA GGAGCGGCGC TGGTGGACAT CGCGGAGTTC 960

GCCGCGGCCG CGGAGGAGTG CCGGCCCCCC GCCAGCCAGC TGCACTCCAT GCGCCTCTCG 1020

CCGCCGGCCC GCTCGCGGTT GGCGCGACGC AGAGCGAACG GCGGCCGTTC TCCGGTCAAG 1080

CAGGTGGAGG GGGAGCCGCG GGCCGCCCTG GCCGGC 1116

Domain Profile

S: 30    kil.....kdrkkvrrevelhvqasghknivelidvfensfedekrlllvlekleGGell  84

         +i+     + r++v+reve+++q++gh+ni+el+++fe    dek ++lv+ek++GG++l

Q: 5     QIIekcqgQRRDRVFREVEMLYQCQGHRNILELVEFFE----DEKAFYLVFEKMHGGSIL  60

         555555567899**************************....******************

S: 85    sriqerkaftekeasevvkdiasalkflhskniahrDlkpenlLyeskeknapvklcDfg  144

         ++iq rk+f+ekeas+vv+diasal+flh+k+iahrDlkpen+L+e  ++++pv++cDf+

Q: 61    THIQMRKHFNEKEASRVVRDIASALHFLHNKGIAHRDLKPENILCELADQVTPVRICDFD  120

         ************************************************************

S: 145   laket...eee....eelktpcltaeyvaPevleaeke.eallydksCDlWslGvilyil  196

         l++++   + +    +el+tpc++aey+aPev+ea++e ea++ydk+CDlWslGvi yil

Q: 121   LGSGVpvgS-TpistPELATPCGSAEYMAPEVVEAFNEeEASFYDKRCDLWSLGVITYIL  179

         ***998551.14566********************9762699******************

S: 197   lcGypPfyskkg...........raiskklkeriqegkyefPeeeWsevseeakdlirkl  245

         l+GypPf++++g           + ++k+l++riqeg+yefPe++W+ vs +akdli+kl

Q: 180   LSGYPPFVGNCGgqcgwdsgqpcSPCQKMLFARIQEGHYEFPEKDWAGVSVHAKDLISKL  239

         ***********88*********99************************************

S: 246   Lkrdpkerltieevlnhpwv  265

         L+r++k+rl++++vl+hpw+

Q: 240   LVRNAKQRLSAAQVLDHPWL  259

         *******************6

Domain Sequence
(FASTA)

QIIEKCQGQR RDRVFREVEM LYQCQGHRNI LELVEFFEDE KAFYLVFEKM HGGSILTHIQ 60

MRKHFNEKEA SRVVRDIASA LHFLHNKGIA HRDLKPENIL CELADQVTPV RICDFDLGSG 120

VPVGSTPIST PELATPCGSA EYMAPEVVEA FNEEEASFYD KRCDLWSLGV ITYILLSGYP 180

PFVGNCGGQC GWDSGQPCSP CQKMLFARIQ EGHYEFPEKD WAGVSVHAKD LISKLLVRNA 240

KQRLSAAQVL DHPWL 255

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>