EKS-PEM-00245

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PEM-00245

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/DMPK	371.9	1.0E-111	96	357	262

Status

Unreviewed

Ensembl Protein

ENSPMAP00000005539

Gene Name

CIT

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPMAG00000004999	ENSPMAP00000005539	ENSPMAT00000005559

Organism

Petromyzon marinus

Protein Length

2077

Protein Sequence
(FASTA)

MMKFKRGWKG SADSPGTEPI SSRFLRLNQL FQGKIAQPGQ HRYLATRDGL LDSLLVLFEE 60

CSDPGLMKHN HIANFVSKHA ETVSELQELR VTSSDFEVRG VVSRGHHSEV QVVRERATGD 120

VYAMKVLQKS LLLHRDNVAL FEEERDVLAR ASSPWLTHLQ YAFQDEDNLY LVMEYHPGGD 180

LLGLLGRYED QLDESMVRFY LAELVLATQS LHQMGYVHRD LKPENVLVDR TGHIKLADFG 240

SAAKLNANKM VSSKLPEGSP DYIAPEVLSS FSGKGSYGPE CDWWSVGVIA YEMVYGKTPF 300

AEGISTKTIS NIKNFQKFVR FPSEPAVSVE FVDLVKGLLC GRVDRLTPDK LLCHPFFAGI 360

DWNNIQHMPP PFVPPLQGDD DTSNFEEVER ERPAAPPTPR QLRQPGFSGN NLPFIGFSYS 420

KALVGLSRTE SVMSVLDSPA KNSSIEKKLQ TKAKELQDAQ DKCHKMEREL EGQQRRVLEL 480

QSDLRHRDKE LKAVEVHRGT LERDLAMYIT ECSSLKRGLE QAQLQVSRED DKALQLLQEI 540

REQNIQLQEI REQEFNSQLE ELRLVVKQLQ EELCVAHRQA GLGDTELRKA RTAADDYRRK 600

LVDYQDRLSK TREQNKAEVA ALQSEMGKIN SESHRKINEL QDKLTKAVQA SAEATELLQN 660

VRRAKDQLER DVELAREKHG NRENMRRRLE ESEERCRTLE GQLKRLAVIE RRESKLKEDL 720

LTKSQQTQQM AEKIKELEEQ CRESEISCRR LEVHVKQKEQ MYEEKIRVMD TQMKLDFADK 780

EVLEQSRTKH EEDAVEKTKV LQDQKATIKA MESRIRALEQ HITELSEANK MVANSSMYTQ 840

RSMYVPADMS YMHTCTCSNE TELKYLTMQA RAAEERLQQS QEASSIARTR VAEIEGRLRE 900

AALAAEQRKL DGQREVGEVA LQLQEREAEL QAARASCFAL EVKLRRVQTE LDETTAEAEE 960

EIASLKASRD DIQKKFETLR ESCSVITEME EQLGELSQEN LELNKQNFYL GKQLEELSGA 1020

ALERGRAQSE VEGLRRELTA RDARLSNQDA TLNMLKTTCT ELEQQIADLE GLNDDLLAKE 1080

RACESSRSAL ETECERREQR VRELLRQQDN DRQNRMRVEQ KSVELRQAIE LAVREHKAES 1140

LALQNIAKEQ RLKADNLGEM LSNLEKKHAM LELSSKGLQK LETERELKLR LMEEQVKLQQ 1200

QLDTHKTRIH RLTQGLQESL DQIDLLKTEK IDLENQTENL QVMFSQERVK MEGTIGQQTK 1260

LIDFLQAKLD QPTKKKKGLF GWKKDDGPTP QQLPLPYTEL KAALDKEKSR SNELEEMLQK 1320

IRVELKAARE EAAHLKTVDH QTSNGSANTQ QQIIMSALVC SPGHQPSPMS LLAPPSHRKQ 1380

SATPDELGRH IKQRMHHNIP HRFSVGLNMR ATKCSVCLDT VHFGRQASKC LGLECQVMCH 1440

PKCSVCLPAT CGLPVEYATH FSEAMVRDKL NSPGLKLPEP PHSLRLQGWM KVPRNGRQGL 1500

LGWDRKYLVL EGSMVKIFDN DNIDSGAPAV DEFELVLADG DVTVHGAVSP SELSNTVKTD 1560

IAYVLKLESH PHTTCWPGRL LYMLAPSFPD KQRWVTALES VVAGGRVAQE RADADTKLLG 1620

NSLLKLEGDD RLDINCSLPL TDQIVLVGAE EGLYALNVAK SALTHVPGVG SVFQIHVVKE 1680

LDQLVMIAGE DRTLCVLDIK KVKQSLAQSH LPAQPEVRPS MFDSVNGCHL FAVGTVEGSS 1740

CICAAMPTHV AVLRYNSGLG RFCLRKEVET SEPCSCIHYT NYSIIFGTNK FYELELKQYT 1800

LEEFLDKNDP SLSSAVYASS YLSFPVAITP VSGAANRDDE YLLCFHEFGV FVDTYGRRSR 1860

TEDLKWSRLP LAFAYREPYL FVTHFNSLEV IEIVHNNGKN SASQPMRAFL NIPNPRYLGP 1920

AISGGAVYLA SSYQNKLRII CCKGNLVREE PDRGAQYPSA ARNASPNKRG PPSYTEYMAK 1980

RRAASPARSL GDSSSSDRSG PAQRDSAQRD FRREPSRARQ VEQRREQSPG RCLDTATRRD 2040

KSGGRGPAGD GPGSRVLPGA VKTPLLQARL LMENSTM 2077

Nucleotide Sequence
(FASTA)

ATGATGAAAT TTAAACGAGG CTGGAAGGGA AGTGCGGATT CTCCTGGCAC AGAACCCATC 60

TCCAGCCGCT TTCTTCGCCT GAATCAGCTG TTTCAGGGCA AGATTGCTCA GCCGGGGCAG 120

CATCGGTACC TGGCCACCCG CGATGGTCTT CTCGACTCAC TCCTGGTCCT CTTTGAGGAG 180

TGCAGTGACC CAGGGCTCAT GAAGCACAAC CACATTGCCA ACTTTGTCAG TAAACATGCC 240

GAGACGGTGT CGGAGCTGCA GGAACTGCGT GTGACCTCAT CGGACTTCGA GGTGAGAGGC 300

GTGGTGAGCC GCGGCCACCA TTCTGAGGTG CAGGTGGTGC GCGAGAGAGC CACCGGTGAT 360

GTTTACGCCA TGAAGGTGCT ACAGAAGAGC CTGCTTCTAC ACCGAGACAA TGTGGCCTTG 420

TTTGAGGAGG AGAGGGACGT CCTGGCCAGA GCCAGCAGCC CCTGGCTCAC GCACCTGCAG 480

TACGCCTTCC AGGATGAAGA CAACCTTTAC CTGGTGATGG AGTATCACCC AGGCGGGGAC 540

CTCCTCGGTT TGCTGGGCCG CTATGAGGAC CAACTAGATG AGAGCATGGT CCGCTTCTAC 600

CTGGCCGAAC TGGTTCTTGC CACGCAGAGC CTGCATCAGA TGGGATACGT GCACAGAGAT 660

TTGAAGCCTG AAAACGTTCT GGTGGACCGT ACTGGACACA TCAAGTTGGC TGACTTTGGC 720

TCAGCTGCCA AGCTCAATGC AAACAAAATG GTGAGCTCAA AGTTACCGGA AGGCTCACCG 780

GACTACATAG CACCAGAGGT CCTGAGCAGT TTCAGTGGGA AGGGTTCCTA CGGGCCTGAG 840

TGCGACTGGT GGTCAGTGGG AGTCATCGCT TATGAAATGG TGTATGGAAA GACCCCCTTT 900

GCTGAGGGCA TTTCCACCAA GACCATCAGC AACATCAAAA ACTTTCAGAA GTTCGTCCGT 960

TTTCCATCCG AGCCGGCGGT GAGCGTGGAG TTTGTGGACC TGGTGAAGGG CCTGCTGTGT 1020

GGCCGTGTGG ACCGCCTTAC ACCTGACAAG CTGCTGTGCC ATCCGTTCTT CGCTGGCATC 1080

GATTGGAATA ACATCCAGCA CATGCCTCCT CCCTTCGTGC CACCTCTGCA AGGTGATGAC 1140

GACACGTCGA ACTTTGAGGA GGTGGAGAGG GAGCGCCCAG CTGCCCCACC GACACCTCGC 1200

CAGCTGAGGC AGCCTGGCTT CTCCGGGAAC AATCTGCCCT TCATCGGCTT CTCCTACAGC 1260

AAGGCCCTGG TTGGCCTTTC ACGCACCGAG TCTGTTATGT CGGTTTTGGA TTCCCCAGCC 1320

AAAAACAGTT CCATTGAGAA AAAACTACAA ACCAAGGCCA AGGAACTCCA AGATGCACAG 1380

GATAAATGTC ACAAGATGGA GAGGGAGCTG GAGGGCCAGC AGAGGAGAGT CCTTGAACTG 1440

CAGTCTGATC TACGTCACAG GGACAAGGAG CTAAAGGCTG TTGAGGTCCA CAGGGGAACA 1500

CTCGAAAGAG ACCTTGCCAT GTACATCACC GAGTGCAGCA GCCTAAAGCG TGGGCTGGAG 1560

CAAGCACAGC TTCAGGTGTC ACGAGAGGAC GATAAAGCTT TGCAGCTGCT GCAGGAGATC 1620

CGCGAGCAGA ACATCCAGCT TCAGGAAATC CGCGAGCAGG AGTTCAACTC CCAGCTGGAG 1680

GAGCTGCGTC TCGTGGTGAA GCAGCTTCAG GAGGAGCTGT GCGTGGCGCA CCGGCAGGCC 1740

GGCCTCGGCG ACACGGAGCT GAGAAAGGCC CGGACGGCCG CTGACGATTA CCGCCGCAAA 1800

CTCGTCGACT ATCAAGACAG ACTCAGCAAG ACCAGAGAAC AAAATAAGGC TGAGGTGGCT 1860

GCTCTACAAA GTGAAATGGG AAAGATAAAT TCTGAGAGCC ATAGGAAAAT AAATGAACTT 1920

CAAGATAAGC TCACTAAGGC AGTGCAGGCC AGCGCCGAGG CGACAGAGCT CCTGCAGAAC 1980

GTGCGGCGCG CCAAGGACCA GCTGGAGAGG GACGTGGAGC TTGCGCGCGA GAAGCACGGC 2040

AACAGAGAAA ACATGCGGCG ACGGCTCGAG GAGAGCGAGG AACGGTGCAG AACTCTGGAA 2100

GGTCAGCTGA AGAGGCTGGC AGTGATTGAG AGAAGAGAGA GCAAGCTGAA AGAAGATCTA 2160

CTTACCAAGT CCCAACAGAC ACAACAAATG GCAGAGAAGA TTAAGGAATT GGAGGAACAG 2220

TGTCGAGAGT CAGAAATCAG TTGTCGGCGG CTGGAGGTCC ACGTCAAACA AAAGGAGCAG 2280

ATGTATGAAG AAAAGATTCG GGTTATGGAT ACACAAATGA AATTAGACTT TGCAGACAAA 2340

GAAGTCTTGG AGCAGAGTCG AACAAAACAC GAGGAGGACG CAGTGGAGAA GACCAAAGTC 2400

TTGCAGGACC AGAAAGCGAC GATCAAAGCC ATGGAGTCAA GGATCCGCGC ACTGGAGCAG 2460

CACATCACGG AGCTGAGCGA GGCCAACAAG ATGGTGGCTA ACAGCAGCAT GTACACGCAG 2520

AGGAGCATGT ACGTGCCAGC TGATATGTCT TATATGCACA CGTGTACGTG CAGTAATGAA 2580

ACTGAATTAA AATATCTTAC AATGCAGGCG CGTGCGGCAG AAGAGAGACT ACAGCAAAGC 2640

CAGGAGGCCA GCAGCATCGC TCGCACAAGG GTGGCTGAAA TCGAGGGCAG GCTCCGTGAG 2700

GCTGCATTAG CGGCAGAGCA GCGGAAGCTG GACGGGCAGC GGGAGGTGGG CGAGGTGGCT 2760

CTGCAGCTGC AGGAGCGGGA GGCCGAGCTG CAAGCTGCGC GTGCCAGCTG CTTCGCTCTC 2820

GAGGTCAAGC TGCGTCGCGT GCAGACGGAG CTGGACGAGA CGACGGCCGA AGCAGAGGAG 2880

GAGATCGCCT CGCTCAAGGC AAGCAGAGAT GACATACAGA AGAAGTTTGA AACCTTGCGG 2940

GAAAGCTGCT CGGTGATCAC GGAGATGGAG GAACAACTGG GAGAGCTGAG CCAGGAGAAC 3000

CTGGAGCTGA ACAAGCAGAA CTTCTACCTG GGCAAGCAGC TGGAGGAGCT GTCTGGCGCC 3060

GCGCTGGAGC GGGGTCGTGC GCAGAGCGAG GTGGAGGGCC TGCGTCGCGA GCTGACCGCG 3120

CGCGACGCGC GTCTCTCGAA CCAAGACGCG ACTCTCAACA TGCTGAAGAC GACGTGCACA 3180

GAGCTGGAGC AGCAGATCGC CGACTTGGAG GGCTTGAACG ACGATCTGCT CGCCAAGGAG 3240

CGCGCGTGCG AGAGCTCCCG CTCCGCCCTG GAGACGGAGT GTGAGCGCCG GGAGCAGCGC 3300

GTGCGGGAGC TGCTGAGGCA GCAGGATAAC GACCGGCAGA ACAGGATGCG TGTTGAACAG 3360

AAGAGTGTGG AGTTGCGGCA GGCCATTGAG TTGGCGGTCC GGGAGCACAA GGCTGAGTCC 3420

CTCGCTCTGC AGAACATAGC CAAGGAACAG CGACTGAAGG CCGACAATCT GGGAGAGATG 3480

CTCAGTAACC TGGAGAAGAA GCATGCCATG CTGGAACTCA GCTCCAAGGG CCTGCAGAAA 3540

CTGGAGACGG AGCGGGAACT GAAGCTGAGG CTCATGGAAG AGCAAGTGAA ACTGCAGCAA 3600

CAGCTGGATA CGCACAAGAC ACGCATCCAC CGGCTGACTC AGGGTCTACA GGAATCCCTG 3660

GACCAGATCG ATCTTCTCAA AACGGAGAAA ATCGATTTGG AGAATCAGAC CGAGAACTTG 3720

CAGGTGATGT TCTCACAAGA GCGGGTGAAG ATGGAAGGAA CGATCGGTCA GCAGACAAAG 3780

CTTATTGACT TCCTGCAAGC TAAACTGGAC CAGCCCACCA AGAAGAAAAA GGGGCTGTTT 3840

GGGTGGAAGA AAGACGATGG GCCCACGCCG CAGCAGCTGC CTTTGCCGTA CACGGAGCTG 3900

AAGGCCGCTC TGGACAAAGA GAAGAGTCGC TCGAATGAGC TGGAGGAGAT GCTGCAGAAG 3960

ATTCGCGTGG AGCTCAAAGC TGCACGGGAG GAAGCTGCGC ATCTCAAAAC CGTGGACCAC 4020

CAGACAAGCA ACGGCTCGGC AAACACCCAG CAGCAGATCA TCATGTCGGC ACTCGTGTGC 4080

TCACCGGGAC ATCAGCCCAG CCCCATGAGT CTCCTGGCTC CACCAAGCCA CAGGAAGCAA 4140

TCAGCCACTC CAGATGAGTT GGGGCGCCAC ATCAAACAGA GAATGCATCA CAATATCCCA 4200

CATCGCTTCA GCGTCGGCCT CAACATGAGA GCCACCAAGT GCTCCGTGTG CCTGGACACC 4260

GTTCACTTTG GCCGCCAGGC CTCCAAGTGC CTCGGCTTAG AGTGCCAGGT GATGTGCCAC 4320

CCCAAGTGCT CCGTGTGCCT GCCTGCCACG TGCGGCCTGC CTGTCGAGTA CGCCACGCAC 4380

TTCAGCGAGG CCATGGTGCG CGACAAACTC AATTCGCCCG GCCTCAAGCT GCCTGAGCCA 4440

CCCCACAGCC TGCGCTTGCA AGGGTGGATG AAGGTGCCTC GGAATGGACG ACAGGGGTTG 4500

CTGGGTTGGG ACCGCAAGTA CTTGGTGCTT GAAGGCTCCA TGGTCAAGAT ATTTGACAAT 4560

GACAATATTG ACTCTGGAGC ACCGGCTGTG GATGAGTTTG AACTCGTGCT CGCCGATGGA 4620

GATGTCACTG TTCACGGAGC AGTCAGCCCG TCGGAGCTGT CGAACACCGT GAAAACAGAC 4680

ATAGCGTACG TGCTCAAGCT GGAGTCGCAC CCCCACACCA CGTGCTGGCC GGGCCGCTTG 4740

CTCTACATGC TGGCGCCCAG CTTCCCCGAC AAGCAGCGCT GGGTGACAGC GCTCGAGTCG 4800

GTTGTGGCGG GCGGGCGTGT GGCACAGGAG CGCGCCGACG CCGACACGAA ACTATTGGGC 4860

AATTCTTTAC TGAAGCTTGA AGGAGATGAC CGATTGGACA TCAATTGTTC TCTGCCCCTT 4920

ACCGATCAGA TTGTGCTCGT TGGAGCTGAG GAGGGCTTGT ACGCATTGAA CGTGGCCAAG 4980

AGCGCGCTCA CACACGTTCC CGGCGTGGGA AGTGTGTTTC AAATTCACGT TGTCAAAGAG 5040

CTGGATCAAC TCGTCATGAT TGCCGGCGAG GATCGTACCC TGTGCGTGCT GGACATTAAG 5100

AAGGTGAAGC AATCACTGGC ACAGTCCCAC CTGCCCGCTC AGCCTGAGGT GCGGCCCAGC 5160

ATGTTTGACA GCGTCAACGG GTGCCATCTT TTTGCCGTGG GCACGGTGGA GGGTTCCTCC 5220

TGCATTTGCG CGGCGATGCC AACGCACGTA GCAGTGCTGC GCTACAACAG CGGCCTCGGT 5280

CGATTCTGTC TGCGCAAGGA GGTGGAGACC AGTGAGCCAT GTAGCTGCAT TCACTACACC 5340

AACTACAGCA TCATCTTTGG CACCAACAAG TTCTACGAGC TCGAGCTGAA ACAGTACACG 5400

CTCGAAGAGT TCCTGGACAA GAATGACCCA TCGCTGTCTT CGGCCGTGTA CGCCTCCTCC 5460

TACCTCAGTT TCCCTGTTGC TATCACACCT GTGTCAGGTG CTGCCAACAG GGATGATGAG 5520

TACCTGCTTT GCTTCCACGA ATTTGGGGTG TTTGTTGACA CGTACGGGCG ACGCAGCAGG 5580

ACAGAGGACC TCAAGTGGAG CCGCCTGCCT TTGGCCTTTG CATACAGAGA GCCTTACTTG 5640

TTTGTGACCC ACTTCAACTC CCTGGAGGTG ATTGAGATTG TCCACAACAA TGGGAAGAAC 5700

TCAGCCAGCC AGCCCATGCG CGCTTTCCTA AACATCCCAA ACCCACGGTA CCTGGGGCCA 5760

GCAATCTCGG GGGGTGCAGT CTACCTGGCT TCTTCCTACC AGAACAAGCT ACGCATCATC 5820

TGCTGCAAGG GCAACCTTGT ACGCGAAGAG CCGGACCGAG GTGCTCAGTA TCCCTCCGCG 5880

GCTCGCAACG CCAGCCCAAA CAAGCGGGGC CCCCCGTCCT ACACGGAGTA CATGGCCAAG 5940

CGGCGCGCCG CATCGCCCGC CCGCTCGCTG GGGGACAGCA GCTCGTCGGA TCGATCAGGC 6000

CCTGCGCAGA GAGACTCTGC GCAGAGAGAC TTCCGCAGAG AGCCTTCGAG AGCCCGGCAG 6060

GTGGAGCAGC GGCGGGAGCA GTCCCCCGGG CGCTGCCTCG ACACGGCTAC GAGGCGCGAC 6120

AAGTCTGGGG GACGCGGCCC AGCCGGCGAT GGGCCCGGCA GCAGGGTCCT CCCCGGAGCT 6180

GTCAAAACTC CGCTTTTGCA AGCCAGGCTG TTGATGGAAA ACTCGACGAT G 6231

Domain Profile

S: 1     feilkviGrGafgevavvrekatekvyamkilkklellkraesaffreerdvlvkadsew  60

         fe++ v+ rG+ +ev+vvre+at++vyamk+l+k+ ll+r+++a+f+eerdvl++a s+w

Q: 96    FEVRGVVSRGHHSEVQVVRERATGDVYAMKVLQKSLLLHRDNVALFEEERDVLARASSPW  155

         8999********************************************************

S: 61    ivqlqyafqdekylylvmeylvGGdlltllskyedklpeelarfylaelvlaldsvhelg  120

         +++lqyafqde++lylvmey +GGdll ll +yed+l+e+++rfylaelvla +s+h++g

Q: 156   LTHLQYAFQDEDNLYLVMEYHPGGDLLGLLGRYEDQLDESMVRFYLAELVLATQSLHQMG  215

         ************************************************************

S: 121   yvhrdikpdnilldksGhikladfGsclklnedgtvkssvavGtpdyispevlkaleegk  180

         yvhrd+kp+n+l+d++GhikladfGs++kln++++v+s+ + G+pdyi+pevl + + gk

Q: 216   YVHRDLKPENVLVDRTGHIKLADFGSAAKLNANKMVSSKLPEGSPDYIAPEVLSSFS-GK  274

         ********************************************************9.9*

S: 181   geygkecdwwslGvilyellvgetpfyaeslvetyskilnhkeslkfpedekvseeakdl  240

         g+yg+ecdwws+Gvi+ye+++g+tpf +  +++t s+i n++++++fp++  vs e+ dl

Q: 275   GSYGPECDWWSVGVIAYEMVYGKTPFAEGISTKTISNIKNFQKFVRFPSEPAVSVEFVDL  334

         ************************************************************

S: 241   ikklltsreerlgregiedlkkhpff  266

         +k ll+ r +rl+ +++    +hpff

Q: 335   VKGLLCGRVDRLTPDKL---LCHPFF  357

         ************99887...899998

Domain Sequence
(FASTA)

FEVRGVVSRG HHSEVQVVRE RATGDVYAMK VLQKSLLLHR DNVALFEEER DVLARASSPW 60

LTHLQYAFQD EDNLYLVMEY HPGGDLLGLL GRYEDQLDES MVRFYLAELV LATQSLHQMG 120

YVHRDLKPEN VLVDRTGHIK LADFGSAAKL NANKMVSSKL PEGSPDYIAP EVLSSFSGKG 180

SYGPECDWWS VGVIAYEMVY GKTPFAEGIS TKTISNIKNF QKFVRFPSEP AVSVEFVDLV 240

KGLLCGRVDR LTPDKLLCHP FF 262

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>