EKS-PEM-00062

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PEM-00062

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NAK	382.5	6.0E-115	45	307	263

Status

Unreviewed

Ensembl Protein

ENSPMAP00000006419

Gene Name

AAK1

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPMAG00000005802	ENSPMAP00000006419	ENSPMAT00000006448

Organism

Petromyzon marinus

Protein Length

951

Protein Sequence
(FASTA)

MKKFFDSRRE GNAGGGGGGG GGGGGGSSSG GAFVGRVYAV GRHQVTVEEV LAEGGFAIVF 60

LVKTSGGVRS ALKRMYVNNE HDLKVCQREI TIMKELSGHK NIVGYLDSSI NAQTSSGVWE 120

VLILMEICRA GQVVNQMNQR LSTGFTECEV LRIFCDTCEA VARLHQCKTP IIHRDLKVEN 180

ILLHDNGNYV LCDFGSATNK ILNPQAHGVS AVEDEIKKYT TLSYRAPEMV NLYNGTPITA 240

KSDIWALGCL LYKLCFFTLP FGESQVAICD GNFTIPDHSR YSHEMHCLIR YMLEPDPDSR 300

PEIYQVACFA FKLSGKECPI LNVNGLSLPN KLPEPLKASE AAARKTQSKT KLTETVGPTE 360

TSIAPRQRPK AGQTNPGAVG ILPLQAVSTP RKRPVATAAA VATQPVIVNI WPPLKPKVPP 420

SMPCPCGKCG NPHSPYTPTL SMPVTNSSNA TASQTAPPAA AQPQPAMPPN GQQQQLTAQN 480

SQPAQPAQPV QQAQQVQIQQ QQQLLQQQQL IQQQQLQQAY LQQQQMIQAQ AQQQAFAFIH 540

STRKNNGIES NAGWQDYSTE YKATAPQLHP PLPLTGQQMV TRVPQNQDIY TGEASQQQGP 600

RLLSVTPPSS PKAQRASGHR RILSDVTYSS VYGVPASRST QVMAAAAAQA SLNKSKSAST 660

TPSGSPRSSQ QDVSRCAANA PDLTTWNPFG DDFTSLSSER LAGNKEEGAR TPVDSLIPGL 720

QAPQTKVQVQ HPPTTTGQVA TQQAPAQTDI FGAVPFVSKP DPFSPLPDSD HPEKLIQGLK 780

SPEPSLLLPD LLPSSDPFGS PGESMHAFHS ALTAFEILTL LYEHAGEYYL LNRILLNTKQ 840

RVFLLQGFSH FVFDLSTVRL KFDFFSLLLS SAGSVGFASL QCAVGEANSL PASIKSDQEA 900

AEPKDDEFDP IPLVPRKSSP SHSRNSSEGS AEGGMPSLGR PLVLVDQLID L 951

Nucleotide Sequence
(FASTA)

ATGAAGAAAT TCTTCGACTC GCGGCGGGAG GGGAACGCCG GCGGCGGAGG AGGTGGAGGA 60

GGAGGCGGCG GCGGCGGCAG CAGCAGCGGC GGCGCCTTCG TGGGCCGGGT GTACGCGGTG 120

GGACGGCACC AGGTCACGGT GGAGGAGGTC CTCGCTGAGG GGGGCTTTGC CATTGTGTTT 180

CTTGTGAAAA CATCGGGCGG AGTTCGCTCT GCACTCAAGC GCATGTACGT TAACAATGAA 240

CACGATCTGA AGGTCTGCCA GAGGGAAATC ACCATCATGA AAGAGCTGTC CGGACATAAA 300

AACATAGTAG GTTATCTGGA CTCGAGTATT AATGCCCAGA CCTCCAGCGG CGTTTGGGAA 360

GTGCTCATTC TCATGGAGAT ATGCCGTGCG GGCCAGGTGG TAAACCAGAT GAATCAAAGG 420

TTGAGCACAG GGTTCACAGA GTGCGAGGTC CTCAGGATAT TTTGTGACAC GTGCGAAGCT 480

GTTGCCCGGC TTCACCAGTG CAAAACGCCG ATTATCCACC GCGATCTGAA GGTTGAGAAC 540

ATCCTGCTTC ACGACAACGG AAACTACGTG CTGTGCGACT TTGGCAGCGC CACCAACAAA 600

ATCCTGAACC CTCAAGCGCA CGGGGTCAGC GCCGTTGAAG ACGAGATTAA AAAGTACACA 660

ACGCTGTCAT ACAGGGCTCC GGAGATGGTC AACTTGTACA ACGGGACACC CATAACAGCA 720

AAGTCCGACA TTTGGGCCCT GGGATGTTTG CTGTACAAGC TGTGCTTCTT TACGCTGCCG 780

TTCGGGGAGA GTCAGGTGGC AATATGCGAC GGGAACTTCA CCATACCCGA CCACTCCCGC 840

TACTCGCATG AAATGCACTG TCTTATACGC TACATGCTGG AGCCTGATCC AGACAGCAGG 900

CCGGAAATCT ACCAGGTGGC CTGCTTTGCA TTCAAGCTTT CAGGCAAAGA ATGTCCCATT 960

CTGAATGTCA ATGGCCTGTC CCTTCCCAAT AAATTGCCGG AGCCACTGAA AGCGAGTGAA 1020

GCTGCTGCCA GGAAGACACA GTCCAAAACC AAACTCACTG AAACGGTTGG CCCCACTGAA 1080

ACGTCGATTG CCCCACGACA AAGGCCTAAG GCAGGGCAGA CAAATCCCGG TGCGGTGGGC 1140

ATCCTGCCCC TGCAGGCAGT CTCCACGCCC AGGAAGAGGC CTGTGGCAAC CGCCGCTGCC 1200

GTCGCCACCC AGCCAGTTAT CGTTAACATC TGGCCACCAT TAAAACCAAA AGTACCACCC 1260

AGCATGCCAT GCCCCTGTGG GAAATGTGGC AACCCTCACT CGCCGTACAC ACCCACACTG 1320

TCCATGCCGG TGACCAACTC GTCCAATGCG ACCGCGAGCC AAACGGCTCC TCCGGCAGCA 1380

GCCCAGCCTC AGCCGGCGAT GCCGCCAAAC GGACAGCAGC AGCAGCTGAC AGCACAGAAC 1440

TCACAGCCGG CTCAACCCGC ACAGCCTGTT CAGCAAGCTC AGCAGGTCCA GATTCAGCAG 1500

CAGCAACAGC TTCTGCAACA ACAGCAGCTG ATCCAACAGC AGCAACTACA ACAGGCCTAC 1560

CTGCAGCAGC AGCAGATGAT TCAAGCTCAA GCCCAACAGC AAGCATTTGC ATTTATACAT 1620

TCAACACGTA AAAACAATGG TATTGAATCG AACGCGGGAT GGCAGGATTA TAGCACGGAG 1680

TATAAGGCAA CTGCGCCGCA GCTTCACCCT CCATTACCTC TTACCGGACA ACAAATGGTT 1740

ACGCGTGTAC CTCAGAATCA GGATATTTAT ACTGGAGAAG CAAGCCAGCA GCAGGGTCCC 1800

CGGCTGCTGT CGGTAACGCC GCCCTCGTCC CCCAAGGCGC AGCGAGCGAG CGGCCACCGT 1860

CGCATCCTGA GCGACGTGAC CTACAGCTCC GTGTACGGCG TGCCGGCCAG CCGCTCCACG 1920

CAGGTCATGG CGGCCGCCGC CGCGCAAGCC TCGCTCAACA AGTCCAAATC TGCAAGCACC 1980

ACCCCGTCAG GATCCCCACG CTCGTCGCAG CAGGATGTTA GCCGGTGTGC TGCCAACGCC 2040

CCGGACCTCA CCACCTGGAA TCCTTTTGGG GACGACTTCA CCTCCCTCTC GTCTGAGCGC 2100

CTTGCGGGAA ACAAGGAGGA AGGCGCACGG ACCCCTGTCG ATAGCCTGAT TCCTGGCCTA 2160

CAGGCTCCCC AGACCAAGGT GCAGGTTCAA CACCCGCCAA CGACCACAGG GCAGGTGGCC 2220

ACGCAGCAAG CTCCGGCACA GACCGACATT TTCGGTGCCG TGCCCTTTGT TTCCAAACCC 2280

GACCCTTTCT CTCCGCTGCC AGACTCCGAC CATCCAGAAA AACTGATCCA AGGCCTAAAA 2340

TCTCCAGAGC CTTCCCTCTT GCTTCCTGAT CTGCTGCCTT CGTCAGACCC ATTTGGCAGC 2400

CCTGGCGAGA GTATGCATGC ATTCCACTCT GCTTTAACAG CCTTTGAAAT ACTAACGCTT 2460

TTATACGAAC ACGCAGGCGA ATACTATCTA CTGAATAGGA TATTGCTAAA CACAAAACAG 2520

CGTGTGTTTT TACTGCAGGG ATTCTCACAT TTTGTGTTTG ATCTTTCGAC GGTTCGTTTG 2580

AAATTCGATT TCTTCTCTCT GCTCCTGTCT TCTGCTGGAT CGGTGGGATT TGCATCACTG 2640

CAATGTGCTG TAGGGGAGGC TAACTCCCTG CCGGCTAGCA TTAAGTCTGA CCAGGAGGCA 2700

GCAGAGCCTA AAGACGATGA ATTTGATCCT ATTCCTCTCG TTCCCAGAAA GAGCTCGCCC 2760

AGCCATTCGC GGAACAGCAG TGAGGGCTCA GCGGAGGGTG GGATGCCCAG CCTAGGTAGG 2820

CCCCTGGTTC TGGTGGACCA GCTGATAGAC CTCTGA 2856

Domain Profile

S: 1     vriekvlaeGGfalvylaedastgekyalKrilvneeedleeikrEieimkklsghkniv  60

         v++e+vlaeGGfa+v+l++ +s g + alKr++vn+e+dl+ ++rEi+imk+lsghkniv

Q: 45    VTVEEVLAEGGFAIVFLVK-TSGGVRSALKRMYVNNEHDLKVCQREITIMKELSGHKNIV  103

         689****************.9999************************************

S: 61    klvdssvkeekdngskevlllleyckkgslvdllnkrlekgelseaeilkilldvtrava  120

          ++dss+++++++g++evl+l+e c++g++v+++n+rl++g ++e e+l+i++d+++ava

Q: 104   GYLDSSINAQTSSGVWEVLILMEICRAGQVVNQMNQRLSTG-FTECEVLRIFCDTCEAVA  162

         ****************************************9.******************

S: 121   alHalsvpliHRDlkveNillsdegelvlcDlGSattaileveskqelsalqeeiekntt  180

         +lH++++p+iHRDlkveNill+d+g++vlcD+GSat++il+++ ++++sa+++ei+k+tt

Q: 163   RLHQCKTPIIHRDLKVENILLHDNGNYVLCDFGSATNKILNPQ-AHGVSAVEDEIKKYTT  221

         *******************************************.9***************

S: 181   lsyrsPElidlysnlvideksDiWaLGcllYklcffesPfeesvklailngkysiPensr  240

         lsyr+PE+++ly++++i+ ksDiWaLGcllYklcff+ Pf+es ++ai++g+++iP++sr

Q: 222   LSYRAPEMVNLYNGTPITAKSDIWALGCLLYKLCFFTLPFGES-QVAICDGNFTIPDHSR  280

         *******************************************.****************

S: 241   yseklkslikkmlevdpeeRptiaqvl  267

         ys+++++li++mle+dp++Rp+i+qv

Q: 281   YSHEMHCLIRYMLEPDPDSRPEIYQVA  307

         *************************96

Domain Sequence
(FASTA)

VTVEEVLAEG GFAIVFLVKT SGGVRSALKR MYVNNEHDLK VCQREITIMK ELSGHKNIVG 60

YLDSSINAQT SSGVWEVLIL MEICRAGQVV NQMNQRLSTG FTECEVLRIF CDTCEAVARL 120

HQCKTPIIHR DLKVENILLH DNGNYVLCDF GSATNKILNP QAHGVSAVED EIKKYTTLSY 180

RAPEMVNLYN GTPITAKSDI WALGCLLYKL CFFTLPFGES QVAICDGNFT IPDHSRYSHE 240

MHCLIRYMLE PDPDSRPEIY QVA 263

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>