EKS-PEM-00238

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PEM-00238

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/Aur	457.7	4.3E-138	15	265	251

Status

Unreviewed

Ensembl Protein

ENSPMAP00000006739

Gene Name

AURKA

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPMAG00000006106	ENSPMAP00000006739	ENSPMAT00000006769

Organism

Petromyzon marinus

Protein Length

296

Protein Sequence
(FASTA)

PGSPCCRKQW SLDNFDIGRP LGKGKFGNVY LAREKSTKFI LALKVLFKSQ LEKSGVEHQL 60

RREIEIQSHL RHPNILRLYG YFHDRTRVYL ILEYAPRGEL YKLLQKLGKF DEERSASYVA 120

DMADALIYCH SKKVIHRDIK PENLLLGLKG ELKIADFGWS VHAPSSRRAT LCGTLDYLPP 180

EMIEGRTHDE KVDLWSLGVL CYEFLVGRPP FESETHNETY RRISKVDLRF PSHLSDGAKD 240

LIANLLKHNP HTRLQLASVL QHPWVKANAK RIVPPAYTAA TTTSAATISA TTSTAN 296

Nucleotide Sequence
(FASTA)

CCTGGCTCCC CGTGTTGCAG GAAGCAGTGG TCGCTGGACA ACTTTGACAT TGGGCGGCCG 60

CTGGGCAAGG GTAAGTTTGG CAACGTGTAC CTGGCGCGGG AGAAGAGCAC CAAGTTCATC 120

CTGGCGCTCA AGGTGCTCTT CAAGTCTCAG CTGGAGAAGT CAGGTGTGGA GCACCAGCTG 180

CGGCGCGAGA TTGAGATCCA GTCGCACCTG CGGCACCCGA ACATCCTGCG CCTCTATGGC 240

TACTTCCACG ACCGCACGCG TGTCTACCTC ATCCTGGAGT ATGCTCCGCG CGGGGAGCTC 300

TACAAGCTGC TGCAGAAGCT GGGGAAGTTT GACGAGGAAC GCAGCGCCTC GTACGTCGCG 360

GACATGGCGG ACGCACTTAT ATACTGCCAT TCGAAGAAGG TGATCCACCG CGACATTAAG 420

CCTGAGAACT TGCTGCTGGG CCTCAAGGGA GAGCTCAAGA TCGCCGACTT TGGGTGGTCG 480

GTGCACGCGC CCTCCTCCAG GCGCGCGACT CTGTGCGGCA CGTTGGACTA CCTGCCACCC 540

GAGATGATCG AGGGGCGCAC GCACGATGAG AAGGTGGACT TGTGGAGCCT GGGCGTGCTC 600

TGCTACGAGT TTCTTGTCGG GCGCCCGCCC TTTGAGTCAG AGACCCACAA CGAAACCTAC 660

CGCCGCATCT CCAAGGTGGA CCTACGCTTC CCATCACACT TGAGCGATGG AGCCAAGGAC 720

CTGATTGCAA ATCTGCTGAA ACACAACCCC CACACCCGCC TGCAGCTCGC TAGCGTCTTG 780

CAGCACCCCT GGGTCAAGGC CAACGCCAAA CGCATTGTGC CGCCCGCCTA CACCGCTGCC 840

ACCACCACCA GTGCCGCCAC CATCAGTGCC ACCACCAGTA CAGCCAACTG A 891

Domain Profile

S: 1     feiGrklGkGkfGnvylarekkskfivalkvlfkeqlekegvekqlrreieiqshlkhpn  60

         f+iGr+lGkGkfGnvylarek++kfi+alkvlfk+qlek+gve+qlrreieiqshl+hpn

Q: 15    FDIGRPLGKGKFGNVYLAREKSTKFILALKVLFKSQLEKSGVEHQLRREIEIQSHLRHPN  74

         9***********************************************************

S: 61    ilrlygyfhdekrvylileyaprGelykelqkskkldeqraakyieeladalsylhkkkv  120

         ilrlygyfhd++rvylileyaprGelyk lqk  k+de+r+a+y+ ++adal y+h+kkv

Q: 75    ILRLYGYFHDRTRVYLILEYAPRGELYKLLQKLGKFDEERSASYVADMADALIYCHSKKV  134

         ************************************************************

S: 121   ihrdikpenlllgskgelkladfGwsvhapsskrktlcGtldylppemvegreydekvdl  180

         ihrdikpenlllg+kgelk+adfGwsvhapss+r tlcGtldylppem+egr++dekvdl

Q: 135   IHRDIKPENLLLGLKGELKIADFGWSVHAPSSRRATLCGTLDYLPPEMIEGRTHDEKVDL  194

         ************************************************************

S: 181   walGvlcyellvGkppfeseskdetykrikkvdlklpssvskgakdliskllkkepkerl  240

         w+lGvlcye+lvG ppfese+++ety+ri+kvdl++ps++s+gakdli++llk++p+ rl

Q: 195   WSLGVLCYEFLVGRPPFESETHNETYRRISKVDLRFPSHLSDGAKDLIANLLKHNPHTRL  254

         ************************************************************

S: 241   tladvlahpwi  251

         +la vl+hpw+

Q: 255   QLASVLQHPWV  265

         **********8

Domain Sequence
(FASTA)

FDIGRPLGKG KFGNVYLARE KSTKFILALK VLFKSQLEKS GVEHQLRREI EIQSHLRHPN 60

ILRLYGYFHD RTRVYLILEY APRGELYKLL QKLGKFDEER SASYVADMAD ALIYCHSKKV 120

IHRDIKPENL LLGLKGELKI ADFGWSVHAP SSRRATLCGT LDYLPPEMIE GRTHDEKVDL 180

WSLGVLCYEF LVGRPPFESE THNETYRRIS KVDLRFPSHL SDGAKDLIAN LLKHNPHTRL 240

QLASVLQHPW V 251

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>