EKS-PEM-00200

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PEM-00200

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/MLK	333.3	5.3E-100	91	351	261

Status

Unreviewed

Ensembl Protein

ENSPMAP00000008358

Gene Name

MAP3K11

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPMAG00000007593	ENSPMAP00000008358	ENSPMAT00000008396

Organism

Petromyzon marinus

Protein Length

1031

Protein Sequence
(FASTA)

PLWTAVFDYE ASAEDELTLR PGDMVEVLSK DSEVSGDVGW WTGKLNNRVG IFPSNYVTCS 60

KSRGSYAKLH NERAPGLFAD PPVEVDFAEL SLEEIIGAGG FGKVYRGTWR GEEVAVKAAR 120

QDPDEDISVT MENVRQEGKL FSMLRHPNII ALKAVCLQAP NLCLIMEYAR GGALNRALAG 180

RRIHPHILLD WAVQIARGMK YLHDEAIVNI IHRDLKSCNV VKVLLQERVE NDDLEAKTLK 240

ITDFGLAREW YKTTMMSAAG TYAWMAPEVI KSSTFSKGSD VWSYGVLLWE LLTGEVPYRG 300

IDGLAVAYGV AVNKLTLPIP STCPEPFSKL MTECWDPDPH SRPPFSRILD ELVAVQESGI 360

FHIPQESFHS LQDDWKLEIQ HMFDELRAKE KELRTREEEL MRASLQQKSQ EELLKRREQE 420

LADREIDVLE RELHILIHHI YQDKPCVKKR KGHFARARLK LSKDGNRISL PSDFQHKITV 480

QASPDRRISV DTPPGSPALI PRLRAIHLSG SSGAKLWGRS AGSPRKEDDR RNGDKKGRGR 540

GGVPGPQRER SSLEDRFCSP SRIDEIGRES PDGVLQTEES ESDGSRLKPV ANGIKVSPGE 600

LPNPRQLLRG VQSSPATPSG SRETGTSDES TSDDDLEKTA VATATADDDD DVPGATCDSS 660

GSATPHDTPH DTPRHTPRHT PRHTPPDVLP PVHQVSKDKE HRSGIALFGC AAVLSVVALG 720

EDVRHAGRIP PASQQQERKR AAFFQRAGLF RRSAGMSVQW RKSPREGGGV NGPQGSPSSS 780

LSICNSTRSL LRSDSEDTTH WPHWPEGSPM SSQVTPGSPA DPLCASLHFE PAVRGHQRNA 840

SDSTITDVSL EQPVSNGVCI SYQALPGLSY FTIPYPSTEP ATVLILSPPP PAGHPSSPER 900

PRTLALTARP RPSPALAHRD PWRVVSSATT ILDPASGQSS GSDTPTNPWP EPLGAKWLAA 960

SDAEERREPP PPPPPQPPQP QPRRPPSEIA TLLDMDVDGQ SKDGTVPLSV RLNALRKDRP 1020

IFYELERQFL G 1031

Nucleotide Sequence
(FASTA)

CCACTTTGGA CGGCCGTGTT TGACTACGAG GCGAGTGCCG AGGACGAGTT GACGCTGCGT 60

CCCGGCGACA TGGTGGAGGT GCTCTCCAAG GACTCGGAGG TGTCTGGCGA CGTGGGCTGG 120

TGGACGGGCA AGCTCAACAA CAGGGTGGGC ATCTTCCCCA GCAACTACGT GACGTGCAGC 180

AAGTCTCGGG GCAGCTACGC GAAGCTGCAC AACGAGAGGG CCCCGGGTTT GTTCGCGGAT 240

CCTCCGGTGG AGGTGGACTT CGCGGAGCTC TCCCTGGAGG AGATCATTGG CGCCGGAGGC 300

TTCGGCAAAG TCTACAGGGG CACGTGGCGC GGCGAGGAGG TGGCCGTGAA GGCCGCTCGC 360

CAGGACCCCG ACGAGGACAT CAGCGTGACG ATGGAGAACG TGAGGCAGGA GGGAAAGCTC 420

TTCTCCATGC TGAGGCATCC GAACATCATT GCGCTGAAGG CCGTGTGCCT GCAGGCGCCC 480

AACCTGTGCC TCATCATGGA GTACGCGCGC GGAGGCGCTC TCAACAGGGC GCTGGCGGGA 540

CGTCGAATCC ACCCGCACAT CCTGCTCGAC TGGGCCGTGC AGATCGCCCG CGGCATGAAG 600

TACCTTCACG ACGAGGCCAT CGTCAATATC ATCCACCGTG ACCTCAAGTC CTGCAATGTC 660

GTGAAAGTCC TGCTGCAGGA GCGCGTGGAG AACGACGACC TGGAGGCCAA GACGCTGAAG 720

ATCACTGATT TTGGGCTGGC CCGCGAGTGG TACAAGACGA CGATGATGAG CGCGGCCGGA 780

ACCTACGCTT GGATGGCGCC CGAGGTCATC AAGTCGTCCA CCTTCTCCAA GGGCAGCGAC 840

GTCTGGAGCT ACGGCGTGCT GCTGTGGGAG CTGCTGACGG GCGAGGTGCC GTACCGCGGC 900

ATCGACGGGC TGGCCGTGGC GTACGGCGTC GCCGTCAACA AGCTCACCCT GCCCATCCCT 960

TCCACCTGCC CGGAGCCCTT CTCCAAGCTC ATGACCGAGT GCTGGGACCC CGATCCGCAC 1020

TCGCGACCCC CGTTCTCACG CATCCTCGAC GAGCTGGTGG CCGTGCAGGA GTCGGGCATC 1080

TTCCACATCC CGCAGGAGTC CTTCCACTCC CTGCAGGACG ACTGGAAGCT GGAGATCCAG 1140

CACATGTTTG ACGAGCTGCG CGCAAAGGAG AAGGAGCTGC GCACGCGGGA GGAGGAGCTG 1200

ATGCGCGCGT CGCTGCAGCA GAAGTCGCAG GAGGAGCTGC TCAAGAGGCG CGAGCAGGAG 1260

CTGGCCGACC GCGAGATCGA CGTGCTGGAG CGAGAGCTGC ACATCCTCAT CCACCACATC 1320

TACCAGGACA AGCCGTGCGT CAAGAAGCGC AAGGGGCACT TTGCGCGCGC GCGGCTCAAG 1380

CTCAGCAAGG ACGGCAACCG CATCAGCCTC CCCTCAGACT TCCAGCACAA GATCACGGTG 1440

CAGGCGTCCC CCGACCGCAG GATAAGCGTC GACACCCCGC CCGGCAGCCC CGCACTCATT 1500

CCCCGCTTGC GCGCCATCCA CCTGTCCGGA TCGAGCGGGG CGAAGCTGTG GGGCCGCAGC 1560

GCAGGCTCGC CGAGAAAGGA AGACGATCGC AGGAACGGGG ACAAGAAGGG GCGAGGGAGG 1620

GGAGGCGTCC CTGGGCCTCA GAGGGAGAGG AGCAGCCTGG AGGACAGGTT TTGTTCCCCA 1680

AGCAGGATAG ACGAGATTGG GAGAGAATCT CCTGATGGGG TGCTACAGAC GGAGGAGAGC 1740

GAAAGTGACG GCAGCAGACT CAAGCCTGTG GCGAATGGGA TCAAGGTGAG CCCAGGAGAA 1800

CTCCCAAATC CCCGGCAGCT GCTGCGAGGA GTCCAGTCTT CGCCCGCAAC GCCCAGCGGC 1860

TCTCGCGAAA CGGGCACGAG CGATGAGTCC ACGAGTGATG ACGACCTTGA GAAAACCGCG 1920

GTCGCCACCG CAACCGCAGA CGATGACGAC GATGTTCCCG GGGCCACGTG CGATTCCTCG 1980

GGCAGTGCCA CCCCGCACGA CACCCCGCAC GACACCCCGC GACACACGCC GCGGCACACG 2040

CCGCGACACA CCCCACCCGA CGTCCTGCCC CCGGTCCACC AGGTCTCCAA AGACAAGGAG 2100

CACCGCAGTG GAATAGCGCT GTTCGGTTGT GCCGCGGTGC TGTCGGTGGT GGCCCTCGGT 2160

GAGGACGTGC GTCACGCTGG GCGCATCCCG CCCGCTTCCC AGCAGCAAGA GCGCAAGCGA 2220

GCAGCGTTTT TCCAGCGCGC GGGGCTGTTC CGTCGCAGCG CGGGAATGTC CGTGCAGTGG 2280

AGGAAGTCGC CACGGGAGGG CGGCGGGGTC AACGGTCCGC AGGGGTCGCC CTCGTCGTCC 2340

CTCTCCATAT GCAACTCGAC GCGCTCCTTG CTGCGCTCGG ACAGCGAGGA CACGACGCAC 2400

TGGCCCCACT GGCCGGAGGG GTCACCGATG TCGTCGCAGG TCACCCCTGG CTCCCCGGCC 2460

GACCCGCTGT GCGCCAGCCT GCACTTTGAG CCGGCGGTCA GAGGCCACCA GCGGAATGCG 2520

TCTGACAGCA CCATCACTGA CGTTTCGCTC GAGCAGCCGG TGTCAAACGG CGTGTGCATC 2580

TCCTACCAAG CTTTACCAGG TTTGAGTTAT TTTACGATCC CTTACCCTTC AACAGAACCG 2640

GCGACAGTGC TGATACTGAG CCCACCGCCG CCGGCGGGAC ACCCTTCGTC CCCGGAGCGG 2700

CCCCGCACGC TGGCGCTCAC CGCCAGGCCA CGCCCCTCGC CGGCGCTCGC TCACCGCGAT 2760

CCCTGGCGCG TCGTCTCCTC GGCGACGACA ATTCTGGACC CGGCGTCCGG CCAGAGCTCC 2820

GGCTCCGACA CGCCCACCAA CCCCTGGCCG GAGCCGCTGG GCGCCAAGTG GCTCGCCGCG 2880

AGCGACGCGG AAGAGCGGAG AGAGCCGCCG CCGCCGCCGC CGCCGCAGCC GCCGCAGCCA 2940

CAGCCCCGCC GCCCCCCCTC GGAGATCGCC ACCCTCCTGG ACATGGACGT TGACGGCCAG 3000

AGCAAGGACG GCACCGTACC GCTGTCGGTG CGCCTCAACG CCTTGCGGAA GGACCGCCCC 3060

ATATTTTACG AGCTCGAAAG ACAGTTCCTT GGA 3093

Domain Profile

S: 2     eleeligsgafgkvykakwrkkevavKklreeaee..kekleklereakllsklshpnii  59

         +lee+ig+g fgkvy+++wr++evavK++r++  e  + ++e++++e kl+s+l+hpnii

Q: 91    SLEEIIGAGGFGKVYRGTWRGEEVAVKAARQDPDEdiSVTMENVRQEGKLFSMLRHPNII  150

         5789****************************99988999********************

S: 60    ellGvcleepnlllvmeyveggsLsnvlhekskreidlevlvswalqiArGmaYLhseap  119

         +l++vcl+ pnl+l+mey++gg+L+++l++   r+i+++ l++wa+qiArGm+YLh+ea

Q: 151   ALKAVCLQAPNLCLIMEYARGGALNRALAG---RRIHPHILLDWAVQIARGMKYLHDEAI  207

         ******************************...9**************************

S: 120   kkiihrdLksknvLl..........seekktlkicdFGtarelskstkmsaagtlawmaP  169

         ++iihrdLks nv+           + e ktlki+dFG are+ k+t+msaagt+awmaP

Q: 208   VNIIHRDLKSCNVVKvllqervendDLEAKTLKITDFGLAREWYKTTMMSAAGTYAWMAP  267

         ************976678*****999999*******************************

S: 170   EvlkeekvseksDvwSygvvLWelltrevPykdlselaiaykvalkglrlpipsscpekl  229

         Ev+k++++s+ sDvwSygv+LWellt+evPy++++ la+ay+va+++l+lpips+cpe++

Q: 268   EVIKSSTFSKGSDVWSYGVLLWELLTGEVPYRGIDGLAVAYGVAVNKLTLPIPSTCPEPF  327

         ************************************************************

S: 230   kkLmkecwnedpekRpsfseivks  253

         +kLm+ecw+ dp++Rp fs i+++

Q: 328   SKLMTECWDPDPHSRPPFSRILDE  351

         ********************9976

Domain Sequence
(FASTA)

SLEEIIGAGG FGKVYRGTWR GEEVAVKAAR QDPDEDISVT MENVRQEGKL FSMLRHPNII 60

ALKAVCLQAP NLCLIMEYAR GGALNRALAG RRIHPHILLD WAVQIARGMK YLHDEAIVNI 120

IHRDLKSCNV VKVLLQERVE NDDLEAKTLK ITDFGLAREW YKTTMMSAAG TYAWMAPEVI 180

KSSTFSKGSD VWSYGVLLWE LLTGEVPYRG IDGLAVAYGV AVNKLTLPIP STCPEPFSKL 240

MTECWDPDPH SRPPFSRILD E 261

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>