EKS-PEM-00240

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PEM-00240

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/ULK	249.4	2.5E-74	4	280	277

Status

Unreviewed

Ensembl Protein

ENSPMAP00000008478

Gene Name

ULK4

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPMAG00000007678	ENSPMAP00000008478	ENSPMAT00000008516

Organism

Petromyzon marinus

Protein Length

1229

Protein Sequence
(FASTA)

MENFVLYEEI GRGRHTVVYK GRRKGTINFV AILCVEKCKR PQITNRVRLT HEVIHENIVQ 60

FLEWYETSNH LWLVVELCTG GSLDAVIAQD KHLPEDVVRE FGIDLVSGLL HIHELGIIFS 120

DLTPAKIMLD GPGNLKLSNL SLARAEGENL QEFFSLVAGE DGDSPDPEAA QGSTLQFRNK 180

GSPVYMAPEV LKGEEFSVAS DFFSLGCMLY ELFTGTPPFY SENFPELMEN IFNEVPATPR 240

VSGENAKKPS PEFVNLLKQL LQKDPSKRPE RQALLEHPFW KGAFSESLPG DIGKPAGKSA 300

LNEDVVDASS ASPPKGSSVA STATSLDRST LSRSFKLEKP DELRPKSVMD TENESMFSLS 360

SRSRAGVGPS AAVPPGTPSR ARSAGQRQPP RTAGTADAST ASQQASEQVF STWELIFHES 420

DLLITPIIDN PKILKPVPVK FDPKTLGVPA ITGEKLAYLP ELELARYLEQ LCGTMAATDK 480

SGSPRTRLNL LCYLCIISTH PHAANRLLNS HLLLVLIQQL QSAQNWDIRG KSARVLALLA 540

HHATELKDTT VISEAMTAVT ELVRESYRNS KLKQCLLPAL GELMCLATRQ EEKRRVSNES 600

WHIPSAAFTV VLRCLRDGEE PLTNHLAAKV VENVCSGASA QTSGFQTAEV GPMLWYLFTH 660

CTVDSLRVTA ISALCRVSRR MPSCFQNVLE KVGLAPVLEA LLSSIARVQQ CLLTLFCIML 720

ASGGHLQRLV HEKEFVAKIV RLLESPSVLI RAKAFLALHQ VLQNNPDMLL YCCQSRLVMY 780

IERDSRRTTP GKDQQQWGHE YLSRCLEILT TLIVHQLPQL TGEVVSVLES VSGRRHPSTV 840

QAKQLKHQLP MLPVLLHLVT SQVFRPQIVN DEFLFKYGIL LGYIKSIDYG ETSIDGAVGQ 900

AQADEAMRVT LSVFEAITQH PVLLTQHHVA VVDSVLPPLT ALVLSQSAER RMFSLRLLSE 960

AASVLLGHEA VSSKASGVSP NAGLLRLVQE TLLPEYENLL MEPDPVPAYA LKLLLALVDY 1020

SPVFIRHLEE LNLVPVLLQV LQEHQESMLG SSMYNVVCLL GNLVANKDTN MTALYQQGLV 1080

ERLVPACMDA GVLVLEGEST SRPASPLLFV LLEMLQELLR RTADMVRRAL QQQKLGDSRS 1140

TQVAEDMLLV NKPFTQLTCT FIQLLCVEES EVGERAMSCL SLVVQLYGAE DADCTGPESA 1200

AHLATALQAT APHPKQQKLL LRIIKRLVS 1229

Nucleotide Sequence
(FASTA)

ATGGAAAACT TCGTCCTTTA CGAGGAGATT GGCCGAGGCC GTCACACCGT GGTCTACAAG 60

GGGCGCCGGA AAGGAACGAT CAACTTTGTG GCTATCCTGT GCGTTGAAAA GTGCAAACGC 120

CCCCAAATTA CGAACAGGGT GAGGTTAACC CATGAAGTTA TTCATGAGAA TATTGTGCAG 180

TTTCTTGAGT GGTACGAGAC CAGCAATCAC TTGTGGCTGG TGGTGGAGCT CTGTACAGGG 240

GGCTCTTTGG ATGCCGTGAT TGCCCAGGAC AAGCACCTCC CAGAGGATGT CGTGCGGGAA 300

TTTGGAATTG ACCTTGTGAG CGGCCTGCTT CACATCCATG AGCTTGGCAT CATCTTCAGT 360

GACCTCACCC CAGCAAAGAT TATGCTCGAT GGACCGGGCA ATCTGAAGCT CAGTAACTTA 420

TCCCTGGCCC GAGCCGAGGG GGAGAATTTA CAAGAGTTCT TCAGCCTGGT GGCCGGAGAG 480

GACGGGGACT CACCTGACCC TGAGGCTGCT CAAGGCAGTA CATTGCAGTT TCGGAATAAA 540

GGCTCGCCAG TCTACATGGC CCCAGAGGTG CTCAAGGGAG AGGAATTCAG TGTTGCCAGT 600

GACTTCTTTT CCCTGGGATG TATGCTGTAT GAACTGTTTA CAGGCACCCC TCCATTTTAT 660

TCTGAAAACT TCCCAGAGCT TATGGAAAAT ATTTTCAATG AGGTGCCAGC TACCCCAAGG 720

GTATCAGGAG AAAATGCAAA GAAACCCTCT CCAGAATTTG TCAACCTGCT GAAACAACTG 780

CTTCAGAAAG ATCCATCTAA AAGGCCGGAG AGGCAGGCTC TGCTAGAGCA CCCATTCTGG 840

AAGGGCGCCT TTTCAGAGTC ACTCCCCGGT GATATCGGCA AGCCTGCAGG GAAGAGTGCT 900

TTAAATGAGG ATGTGGTTGA CGCCTCATCT GCATCGCCTC CCAAGGGCAG CTCCGTGGCT 960

TCCACAGCCA CCAGCCTAGA CCGCAGCACC CTCAGCCGGT CCTTCAAGCT CGAGAAACCG 1020

GATGAATTGA GGCCTAAAAG TGTCATGGAC ACGGAGAACG AGTCAATGTT TTCTCTCAGT 1080

TCACGATCCC GGGCAGGTGT GGGTCCAAGT GCTGCCGTTC CGCCAGGTAC CCCAAGCCGG 1140

GCCAGGTCAG CCGGACAGAG ACAGCCTCCC AGAACGGCAG GCACTGCAGA TGCATCGACA 1200

GCCTCGCAGC AAGCCAGCGA GCAGGTCTTT TCTACATGGG AGCTGATTTT TCATGAGTCA 1260

GACCTGCTCA TCACTCCAAT AATTGATAAC CCCAAGATCC TGAAGCCAGT ACCAGTAAAG 1320

TTTGACCCAA AGACCCTTGG TGTCCCTGCT ATTACAGGAG AGAAGCTTGC GTACCTGCCT 1380

GAACTGGAGT TGGCCCGGTA TCTGGAGCAG CTGTGCGGCA CGATGGCAGC CACTGACAAG 1440

TCAGGCTCTC CACGCACACG ACTCAACCTC CTGTGCTACC TGTGCATCAT CAGCACGCAT 1500

CCACATGCCG CCAACCGTCT TCTCAACTCA CATTTGTTGT TAGTGCTGAT CCAGCAGCTG 1560

CAGTCTGCTC AAAACTGGGA CATCCGGGGG AAGTCGGCTC GTGTTCTGGC TTTGCTGGCC 1620

CATCATGCCA CGGAGCTCAA GGATACCACC GTGATATCTG AGGCCATGAC TGCCGTGACG 1680

GAGCTGGTGC GCGAGAGCTA TAGGAACAGC AAGCTGAAGC AGTGCCTGCT GCCTGCACTA 1740

GGAGAACTCA TGTGCCTTGC CACGAGACAG GAGGAGAAGA GAAGGGTATC GAATGAGAGC 1800

TGGCATATCC CAAGTGCTGC ATTCACTGTG GTACTGCGAT GCTTACGTGA TGGGGAGGAG 1860

CCTCTAACGA ACCACCTGGC AGCAAAAGTA GTGGAGAATG TGTGCAGTGG AGCCTCTGCG 1920

CAGACGAGCG GCTTTCAGAC GGCAGAGGTG GGGCCCATGC TGTGGTACCT GTTCACCCAC 1980

TGCACCGTCG ACTCCCTGCG TGTCACTGCC ATCTCTGCAC TTTGTCGCGT GAGCCGCCGC 2040

ATGCCAAGCT GCTTTCAGAA TGTGCTGGAG AAGGTGGGGC TGGCACCTGT GCTTGAGGCA 2100

CTGCTGTCGA GCATTGCGCG CGTACAGCAG TGCCTGCTCA CCCTGTTCTG CATCATGCTG 2160

GCGTCGGGTG GCCACCTCCA GCGCCTTGTT CATGAGAAGG AGTTTGTGGC AAAGATCGTG 2220

CGTCTGCTGG AGAGTCCGTC GGTGCTAATC CGAGCCAAGG CTTTCCTGGC ACTCCATCAG 2280

GTGCTGCAAA ACAACCCCGA CATGCTGCTC TACTGCTGTC AGTCCCGGCT GGTGATGTAC 2340

ATTGAGAGGG ACTCTCGACG CACAACTCCG GGTAAGGATC AACAGCAGTG GGGGCACGAA 2400

TACCTGTCCC GGTGCCTGGA GATCCTCACT ACTCTCATTG TCCACCAGCT GCCCCAGCTT 2460

ACTGGTGAGG TTGTGTCAGT CCTGGAGAGT GTGTCCGGTA GGCGGCACCC ATCCACAGTC 2520

CAGGCCAAGC AGCTCAAGCA TCAGCTGCCC ATGCTGCCAG TCCTCTTACA TCTTGTCACC 2580

TCACAGGTGT TCAGGCCACA GATTGTGAAT GATGAGTTTC TTTTCAAGTA TGGGATTCTC 2640

TTGGGGTATA TCAAATCAAT CGACTATGGA GAGACCAGCA TTGATGGCGC TGTTGGCCAG 2700

GCACAGGCGG ACGAAGCAAT GAGAGTAACG CTATCGGTGT TCGAGGCCAT CACCCAGCAC 2760

CCTGTTCTGC TGACTCAGCA CCACGTTGCC GTTGTGGACT CTGTTCTGCC TCCTCTGACT 2820

GCTCTTGTTC TGAGCCAAAG TGCGGAGCGC CGTATGTTCA GCTTGCGGCT GCTGTCAGAG 2880

GCGGCATCTG TGCTGCTTGG ACACGAGGCT GTGAGCAGCA AGGCCAGCGG TGTCTCGCCT 2940

AATGCCGGCC TGCTCCGCCT CGTCCAGGAG ACCCTTCTAC CAGAGTATGA GAACCTGCTG 3000

ATGGAACCAG ATCCTGTGCC AGCATATGCT CTCAAGCTTC TACTCGCCCT GGTGGATTAC 3060

AGTCCTGTGT TTATCCGGCA CCTGGAGGAG TTAAACCTTG TTCCAGTACT ATTGCAAGTA 3120

TTGCAGGAGC ACCAGGAGAG CATGCTGGGA AGCAGCATGT ACAACGTGGT GTGCTTATTG 3180

GGCAATCTGG TTGCCAATAA GGACACCAAC ATGACCGCAC TCTATCAGCA AGGCCTGGTG 3240

GAGCGCTTGG TGCCTGCGTG CATGGACGCC GGTGTGCTGG TACTGGAGGG GGAGAGCACC 3300

AGCAGGCCGG CCTCTCCGCT GCTGTTTGTA CTGCTGGAGA TGCTGCAAGA GCTGCTGAGA 3360

CGCACGGCGG ATATGGTGCG GCGTGCGCTG CAGCAACAGA AGTTGGGGGA TTCACGCAGC 3420

ACGCAGGTTG CGGAGGACAT GCTACTTGTG AACAAGCCAT TCACTCAGCT GACCTGCACC 3480

TTCATACAGC TGCTGTGCGT GGAGGAGAGT GAGGTGGGGG AGCGCGCTAT GAGCTGCCTG 3540

TCGCTGGTAG TGCAGCTGTA CGGTGCGGAG GATGCCGACT GCACGGGTCC CGAGAGCGCC 3600

GCACACCTCG CCACCGCTCT GCAAGCCACC GCTCCACACC CCAAACAGCA GAAGCTGCTC 3660

CTGCGCATCA TCAAGAGGCT GGTGAGT 3687

Domain Profile

S: 1     ysleeeiGkGsfavvykgrlrkktsqvvAikvvekkklkkslenlekeikilkelkheni  60

         ++l+eeiG+G  +vvykgr rk t+++vAi++vek+k+    +++++ +++++e+ heni

Q: 4     FVLYEEIGRGRHTVVYKGR-RKGTINFVAILCVEKCKR----PQITNRVRLTHEVIHENI  58

         7899***************.*****************9....9*****************

S: 61    valldveetskevylvmeycaggdLakllkqkkeLsedtvreflqqlasalkaLhskkiv  120

         v++l+++ets++++lv+e+c+gg+L+++++q+k+L+ed+vref  +l+s+l ++h+++i+

Q: 59    VQFLEWYETSNHLWLVVELCTGGSLDAVIAQDKHLPEDVVREFGIDLVSGLLHIHELGII  118

         ************************************************************

S: 121   hrDlkPqniLlsyadakkelkkvtlkladFglarvlkee.....................  159

         + Dl P +i+l+        ++++lkl++ +lar+  e+

Q: 119   FSDLTPAKIMLD--------GPGNLKLSNLSLARAEGENlqeffslvagedgdspdpeaa  170

         ************........9***************************************

S: 160   ...smaatlkGsplYmaPEvvkeqqydakaDlWSiGtilyellvGkpPfaaesiseLvek  216

            +++ + kGsp+YmaPEv+k +++++ +D++S+G++lyel++G+pPf++e++ eL+e

Q: 171   qgsTLQFRNKGSPVYMAPEVLKGEEFSVASDFFSLGCMLYELFTGTPPFYSENFPELMEN  230

         *99899999***************************************************

S: 217   iekndvleppipke....isselkdllqsLLqrdpkkRisfeelfahpfl  262

         i ++   +p++  e     s+e+ +ll++LLq+dp+kR + + l++hpf+

Q: 231   IFNEVPATPRVSGEnakkPSPEFVNLLKQLLQKDPSKRPERQALLEHPFW  280

         *655444666544334449*****************************98

Domain Sequence
(FASTA)

FVLYEEIGRG RHTVVYKGRR KGTINFVAIL CVEKCKRPQI TNRVRLTHEV IHENIVQFLE 60

WYETSNHLWL VVELCTGGSL DAVIAQDKHL PEDVVREFGI DLVSGLLHIH ELGIIFSDLT 120

PAKIMLDGPG NLKLSNLSLA RAEGENLQEF FSLVAGEDGD SPDPEAAQGS TLQFRNKGSP 180

VYMAPEVLKG EEFSVASDFF SLGCMLYELF TGTPPFYSEN FPELMENIFN EVPATPRVSG 240

ENAKKPSPEF VNLLKQLLQK DPSKRPERQA LLEHPFW 277

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>