EKS-PEM-00008

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-PEM-00008

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/InsR	505.8	1.2E-152	61	326	266

Status

Unreviewed

Ensembl Protein

ENSPMAP00000009441

Gene Name

INSR

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPMAG00000008570	ENSPMAP00000009446	ENSPMAT00000009485
ENSPMAG00000008570	ENSPMAP00000009441	ENSPMAT00000009481

Organism

Petromyzon marinus

Protein Length

492

Protein Sequence
(FASTA)

LYLMIAPFEF VFIALCVCIL CLNRNEAAVP NGVLYASVNP EYFSTADVYI ADEWEVERDK 60

VKMMRELGQG TFGMVYEGLA RGIVKGEDET RVAIKTVNET ATMRERYEFL NEASVMKSFN 120

CHHVVRLLGV VSQAQPILVI MELMTRGDLK SYLRSLRPDA EKKPTRPPSS LPEMLQMAGE 180

IADGMAYLNA KKFVHRDLAA RNCMVAEDFT VKIGDFGMTR DIYETDYYRK GGKGLLPVRW 240

MSPESLKDGV FTTHSDVWSF GVVLWEIATQ AEQPYQGLSN EQVLKFVMDG GLLVLPPACP 300

ERLQELIRKC WQYNPRMRPT FLEILDGLAP DLHPSFHEFS FYHSEENRPP DHDRDPPGME 360

MQSMQSMQSM QSYPLDEESC QLEGASPSKS LSPSEPSSPV PVLGVQAVDE RNQPYARLDT 420

LPAEKPPCAE SSSESSVPSS PTGSGSVSLS PTKAGVNLPS PTASGNKQLP YAHMNGGRKD 480

GRALPLPQST AC 492

Nucleotide Sequence
(FASTA)

TTATACCTAA TGATTGCCCC GTTTGAGTTC GTATTTATTG CTTTGTGTGT ATGCATTCTG 60

TGTTTGAACA GAAATGAGGC AGCAGTACCC AATGGAGTTT TGTATGCATC GGTCAACCCT 120

GAGTATTTCA GCACAGCTGA TGTTTACATC GCTGACGAGT GGGAGGTGGA GAGGGACAAG 180

GTGAAGATGA TGCGGGAGTT GGGCCAGGGC ACGTTCGGCA TGGTGTACGA GGGCCTGGCC 240

CGCGGCATCG TCAAGGGCGA GGACGAGACG CGCGTGGCCA TCAAGACGGT GAACGAGACG 300

GCCACCATGC GCGAGCGTTA CGAGTTCCTC AACGAGGCCT CGGTCATGAA GTCCTTCAAC 360

TGTCACCACG TGGTTCGGCT TTTGGGAGTT GTTTCACAGG CTCAGCCCAT TTTGGTGATA 420

ATGGAGCTGA TGACACGTGG GGACCTGAAA AGTTATCTCC GGTCTCTGCG ACCTGATGCT 480

GAGAAAAAGC CAACACGGCC CCCATCAAGC CTGCCGGAGA TGCTGCAGAT GGCGGGCGAA 540

ATTGCCGATG GGATGGCTTA TCTCAACGCC AAAAAGTTTG TGCATCGTGA CCTCGCTGCT 600

AGAAACTGTA TGGTGGCGGA GGACTTCACC GTCAAAATCG GCGATTTTGG AATGACACGG 660

GACATTTATG AAACCGATTA CTATCGCAAG GGCGGGAAGG GGCTGCTTCC CGTCCGCTGG 720

ATGTCTCCTG AGTCACTCAA AGACGGTGTG TTCACCACCC ACTCGGACGT TTGGTCTTTT 780

GGAGTTGTTC TGTGGGAGAT AGCCACGCAA GCCGAGCAAC CATATCAGGG CTTATCCAAC 840

GAGCAGGTCC TCAAGTTTGT CATGGACGGT GGGCTATTGG TATTGCCCCC AGCTTGTCCA 900

GAAAGGCTAC AAGAGCTAAT TCGCAAGTGC TGGCAGTACA ACCCACGCAT GCGACCAACG 960

TTTCTGGAAA TCCTTGACGG GCTTGCCCCT GACCTTCATC CATCTTTCCA CGAGTTCTCG 1020

TTCTATCACA GCGAGGAGAA CAGACCTCCG GATCACGATC GTGACCCACC TGGGATGGAG 1080

ATGCAGAGCA TGCAGAGCAT GCAGAGCATG CAGAGCTACC CCCTCGATGA AGAATCCTGT 1140

CAGCTTGAGG GGGCATCACC GAGCAAGTCT CTTTCACCCT CCGAGCCTTC CTCTCCAGTC 1200

CCTGTGCTTG GTGTTCAAGC GGTGGATGAG CGAAATCAGC CATATGCACG ATTAGACACC 1260

CTCCCAGCAG AGAAGCCTCC GTGTGCTGAA TCATCGTCTG AGAGCTCGGT GCCATCCTCT 1320

CCTACCGGCT CCGGTTCCGT GTCATTATCG CCCACAAAAG CCGGGGTCAA CCTACCGTCG 1380

CCGACTGCAT CGGGCAACAA ACAGCTTCCT TATGCCCACA TGAATGGTGG AAGAAAAGAT 1440

GGGCGGGCAT TGCCACTCCC TCAGTCAACA GCATGTTAG 1479

Domain Profile

S: 1     ivllrelGqGsfGmvyeGvakdvvkgeeetrvaiktvneaassrerieflkeasvmkefk  60

         + ++relGqG+fGmvyeG+a+++vkge etrvaiktvne+a++rer efl+easvmk+f+

Q: 61    VKMMRELGQGTFGMVYEGLARGIVKGEDETRVAIKTVNETATMRERYEFLNEASVMKSFN  120

         5789********************************************************

S: 61    thhvvrllGvvskgqpalvvmelmkkGdlksylrslrpeeeneaalappaldkliqmaae  120

         +hhvvrllGvvs++qp+lv+melm++Gdlksylrslrp++e++++++p +l ++ qma+e

Q: 121   CHHVVRLLGVVSQAQPILVIMELMTRGDLKSYLRSLRPDAEKKPTRPPSSLPEMLQMAGE  180

         ************************************************************

S: 121   iadGmayleakkfvhrdlaarncmvaedltvkiGdfGmtrdiyetdyyrkggkgllpvrw  180

         iadGmayl+akkfvhrdlaarncmvaed+tvkiGdfGmtrdiyetdyyrkggkgllpvrw

Q: 181   IADGMAYLNAKKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRW  240

         ************************************************************

S: 181   mspeslkdGvftsksdvwsfGvvlweivtlaeqpyqGlsneqvlkfvldggvlekpencp  240

         mspeslkdGvft++sdvwsfGvvlwei+t aeqpyqGlsneqvlkfv+dgg+l  p +cp

Q: 241   MSPESLKDGVFTTHSDVWSFGVVLWEIATQAEQPYQGLSNEQVLKFVMDGGLLVLPPACP  300

         ************************************************************

S: 241   elltelmrlcwqynpklrpsfleive  266

         e+l+el+r+cwqynp++rp+flei++

Q: 301   ERLQELIRKCWQYNPRMRPTFLEILD  326

         ************************97

Domain Sequence
(FASTA)

VKMMRELGQG TFGMVYEGLA RGIVKGEDET RVAIKTVNET ATMRERYEFL NEASVMKSFN 60

CHHVVRLLGV VSQAQPILVI MELMTRGDLK SYLRSLRPDA EKKPTRPPSS LPEMLQMAGE 120

IADGMAYLNA KKFVHRDLAA RNCMVAEDFT VKIGDFGMTR DIYETDYYRK GGKGLLPVRW 180

MSPESLKDGV FTTHSDVWSF GVVLWEIATQ AEQPYQGLSN EQVLKFVMDG GLLVLPPACP 240

ERLQELIRKC WQYNPRMRPT FLEILD 266

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>