EKS-POA-00473

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-POA-00473

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/RSKL	315.2	7.5E-94	654	875	222

Status

Unreviewed

Ensembl Protein

ENSPPYP00000000233

UniProt Accession

H2N3Q9;

Protein Name

Protein Synonyms/Alias

Gene Name

RPS6KC1

Gene Synonyms/Alias

RPS6KC1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPPYG00000000226	ENSPPYP00000000233	ENSPPYT00000000248

Organism

Pongo abelii

Functional Description

Protein Length

885

Protein Sequence
(FASTA)

MASNQNSPIR TFGLNLSSDS SALGAVASDS EQSKTEEERE SRSLFPGSLK PKLGKRDYLE 60

KAGELIKLAL KKEEEDDYEA ASDFYRKGVD LLLEGVQGES SPTRREAVKR RTAEYLMRAE 120

SISSLFGKPQ LDDVSQPPGS LSSRPPWNLR SPAEELKAFR VLGVIDKVLL VMDTRTEQTF 180

ILKGLRKSSE YSRNRKTIIP RCVPNMVCLH KYIISEESVF LVLQHAEGGK LWSYISKFLN 240

RSPEESFDIK EVKKPTLEKV HLQQPTSSSQ DSSSFESRGS DGGSMLKALP LKSSLTPSSQ 300

DDSNQEDDGQ DSSPKWPDSG SSSEEECTTS YLTLCNEYGQ EKIEPGSLNE EPFMKTEGNA 360

VDTKAIKSFP AHLAADSDSP STELRAHELK FFPNDDPEAV SSPRTSDSLS RSKNSPMEFF 420

RIDSKDSASE LLGLDFGEKL YSLKSEPLKP FFTLPDGDSA SRSFNTSESK VEFKAQDTIS 480

RGSDDSVPVI SFKDAAFDDV SGTDEGRPDL LVNLPGELES TREAAAMGPT KFTQTNIGII 540

ENKLLEAPDV LCLRLSTEQC QAHEEKGIEE LSDPSGPKSY SITEKHYAQE DPRMLFVAAV 600

DHSSSGDMSL LPSSDPKFQG LGVVESAVTA KNTEESLFRI CSPLSGANEY NASTDTLKTE 660

EVLLFTDQTD DLAKEDPTSL FQRDSETKGE NGLALEGDKE IHQIFEDLDK KLALTSRFYI 720

PEGCIQRWAA EMVVALDALH REGIVCRDLN PNNILLNDRG HIQLTYFSRW SEVEDSCDSD 780

AVERMYCAPE VGAITEETEA CDWWSLGAVL FELLTGKTLV ECHPAGINTH TTLNMPECVS 840

EEARSLIQQL LQFNPLERLG AGVAGVEDIK SHPFFTPVDW AELMR 885

Nucleotide Sequence
(FASTA)

ATGGCTTCCA ATCAAAATTC TCCCATTAGA ACTTTTGGTC TCAATCTTTC TTCGGATTCT 60

TCAGCACTAG GGGCTGTTGC TTCTGACAGT GAACAGAGCA AAACAGAAGA AGAACGGGAA 120

AGTCGTAGCC TCTTTCCTGG CAGTTTAAAA CCGAAGCTTG GCAAGAGAGA TTATTTGGAG 180

AAAGCAGGAG AATTAATAAA GCTGGCTTTA AAAAAGGAAG AAGAAGACGA CTATGAAGCT 240

GCTTCTGATT TTTATAGGAA GGGAGTTGAT TTACTCCTAG AAGGTGTTCA AGGAGAGTCA 300

AGCCCTACCC GTCGAGAAGC TGTGAAGAGA AGAACAGCTG AGTACCTCAT GCGGGCAGAA 360

AGTATCTCTA GTCTTTTTGG GAAACCTCAG CTTGATGATG TATCTCAGCC TCCAGGATCA 420

CTAAGTTCAA GGCCCCCTTG GAACCTAAGG AGCCCTGCCG AGGAGCTGAA GGCCTTCAGA 480

GTCCTTGGGG TGATTGACAA GGTTTTACTT GTAATGGACA CAAGGACAGA ACAGACTTTC 540

ATTTTAAAAG GTCTAAGGAA AAGCAGTGAA TACAGCAGGA ACAGAAAGAC CATCATCCCC 600

CGCTGTGTGC CCAACATGGT GTGTCTGCAT AAGTACATCA TCTCTGAGGA GTCAGTATTT 660

CTTGTGCTGC AGCATGCGGA AGGTGGCAAA CTGTGGTCAT ATATCAGTAA ATTTCTAAAC 720

AGAAGTCCTG AAGAAAGCTT TGACATCAAG GAAGTGAAAA AACCTACACT TGAAAAAGTT 780

CACCTGCAAC AGCCAACTTC TAGTTCTCAG GACAGCAGTA GCTTTGAATC CAGAGGAAGT 840

GATGGTGGAA GCATGCTTAA AGCTCTGCCT TTGAAGAGTA GTCTTACTCC AAGTTCTCAA 900

GATGACAGCA ACCAGGAAGA TGATGGCCAA GATAGCTCTC CAAAGTGGCC AGATTCTGGT 960

TCAAGTTCAG AAGAAGAATG TACTACTAGT TATTTAACAT TATGCAATGA ATATGGGCAA 1020

GAAAAGATTG AACCAGGGTC TTTGAATGAG GAGCCCTTCA TGAAGACTGA AGGGAATGCT 1080

GTTGATACTA AAGCTATTAA AAGCTTCCCA GCACACCTTG CTGCTGACAG TGACAGCCCC 1140

AGCACAGAGC TGAGAGCTCA CGAGCTGAAG TTCTTCCCCA ACGATGACCC AGAAGCAGTT 1200

AGTTCTCCAA GAACATCAGA TTCCCTCAGT AGATCAAAAA ATAGCCCCAT GGAATTCTTT 1260

AGGATAGACA GTAAGGATAG CGCAAGTGAA CTCCTGGGAC TTGACTTTGG AGAAAAATTG 1320

TATAGTCTAA AATCAGAACC TTTGAAACCA TTCTTTACTC TTCCAGATGG AGACAGTGCT 1380

TCTAGGAGTT TTAATACTAG TGAAAGCAAG GTAGAGTTTA AAGCTCAGGA CACCATTAGC 1440

AGGGGCTCAG ATGACTCAGT GCCAGTTATT TCATTTAAAG ATGCTGCTTT TGATGATGTC 1500

AGTGGTACTG ATGAAGGAAG ACCTGATCTT CTTGTAAATT TACCTGGTGA ATTGGAGTCA 1560

ACAAGAGAAG CTGCAGCAAT GGGACCTACT AAGTTTACAC AAACTAATAT AGGGATAATA 1620

GAAAATAAAC TCTTGGAAGC CCCTGATGTT TTATGCCTCA GGCTTAGTAC TGAACAATGC 1680

CAAGCACATG AGGAGAAAGG CATAGAGGAA CTGAGTGATC CCTCTGGGCC CAAATCCTAT 1740

AGTATAACAG AGAAACACTA TGCACAGGAG GATCCCAGGA TGTTATTTGT AGCAGCTGTT 1800

GATCATAGTA GTTCAGGAGA TATGTCTTTG TTACCCAGCT CAGATCCTAA GTTTCAAGGA 1860

CTTGGAGTGG TTGAGTCAGC AGTAACTGCA AAAAACACAG AAGAAAGCTT ATTCCGTATT 1920

TGTAGTCCAC TCTCAGGTGC TAATGAATAT AATGCAAGCA CAGACACTTT AAAAACAGAA 1980

GAAGTATTGC TGTTTACAGA TCAGACTGAT GATTTGGCTA AAGAGGATCC AACTTCTTTA 2040

TTCCAGAGAG ACTCTGAGAC TAAGGGAGAA AATGGTTTAG CGCTAGAAGG AGACAAGGAA 2100

ATACATCAGA TTTTTGAGGA CCTTGATAAA AAATTAGCAC TAACCTCCAG GTTTTACATC 2160

CCAGAGGGCT GCATTCAAAG ATGGGCAGCT GAAATGGTGG TAGCCCTTGA TGCTTTACAT 2220

AGAGAGGGAA TTGTGTGCCG CGATTTGAAC CCAAACAACA TCTTATTGAA TGATAGAGGA 2280

CACATTCAGC TAACGTATTT TAGCAGGTGG AGTGAGGTTG AAGATTCCTG TGACAGCGAT 2340

GCCGTAGAGA GAATGTACTG TGCCCCAGAG GTTGGAGCAA TCACTGAAGA AACTGAAGCC 2400

TGTGATTGGT GGAGTTTGGG TGCTGTCCTC TTTGAACTTC TCACTGGCAA GACTCTGGTT 2460

GAATGCCATC CAGCAGGAAT AAATACTCAC ACTACTTTGA ACATGCCAGA ATGTGTCTCT 2520

GAAGAGGCTC GCTCACTCAT TCAACAGCTC TTGCAGTTCA ATCCTCTGGA ACGACTTGGT 2580

GCTGGAGTTG CTGGTGTTGA AGATATCAAA TCTCATCCAT TTTTTACCCC TGTGGATTGG 2640

GCAGAACTGA TGAGATGA 2658

Domain Profile

S: 121   derislekp..rtesllllvgeeptsrsqreaeeesearvklefssdkskaprGnrirre  178

          +++ +e+    t+++++l++e+pts++qr++e+++e+   le++

Q: 654   TDTLKTEEVllFTDQTDDLAKEDPTSLFQRDSETKGENGLALEGD---------------  698

         455555553225999*************************99999...............

S: 179   gqnsspssskeiklvsedadkslealsrgldkalqsvdkalslrravwslpEelikqWaa  238

                  kei++++ed+dk+l+++sr                   +++pE++i++Waa

Q: 699   ---------KEIHQIFEDLDKKLALTSR-------------------FYIPEGCIQRWAA  730

         .........99*****************...................*************

S: 239   elvvaleaLHeegvlirDlnadniLldskGhllltYfgrwsevekscrreavdnlysAPE  298

         e+vval+aLH+eg+++rDln++niLl+++Gh++ltYf+rwseve+sc+++av+++y+APE

Q: 731   EMVVALDALHREGIVCRDLNPNNILLNDRGHIQLTYFSRWSEVEDSCDSDAVERMYCAPE  790

         ************************************************************

S: 299   vgaiselteasDwWslGalLyelLtGkalaeahPsgiqahtelqlPevvSeeAkdLleeL  358

         vgai+e+tea+DwWslGa+L+elLtGk+l+e+hP+gi++ht+l++Pe+vSeeA++L+++L

Q: 791   VGAITEETEACDWWSLGAVLFELLTGKTLVECHPAGINTHTTLNMPECVSEEARSLIQQL  850

         ************************************************************

S: 359   LqfePalRlGaGeagvdelkaHPFF  383

         Lqf+P +RlGaG+agv+++k+HPFF

Q: 851   LQFNPLERLGAGVAGVEDIKSHPFF  875

         ************************9

Domain Sequence
(FASTA)

TDTLKTEEVL LFTDQTDDLA KEDPTSLFQR DSETKGENGL ALEGDKEIHQ IFEDLDKKLA 60

LTSRFYIPEG CIQRWAAEMV VALDALHREG IVCRDLNPNN ILLNDRGHIQ LTYFSRWSEV 120

EDSCDSDAVE RMYCAPEVGA ITEETEACDW WSLGAVLFEL LTGKTLVECH PAGINTHTTL 180

NMPECVSEEA RSLIQQLLQF NPLERLGAGV AGVEDIKSHP FF 222

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005769	; C:early endosome
GO:0005524	; F:ATP binding
GO:0035091	; F:phosphatidylinositol binding
GO:0004672	; F:protein kinase activity
GO:0007154	; P:cell communication

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR007330	; MIT.
IPR001683	; Phox.
IPR000719	; Prot_kinase_cat_dom.

Pfam

PF04212	; MIT; 1.
PF00069	; Pkinase; 1.
PF00787	; PX; 1.

SMARTs

SM00745	; MIT; 1.
SM00312	; PX; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS50195	; PX; 1.

Prints

Created Date

20-Feb-2013