EKS-POA-00137

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-POA-00137

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/CDC7	553.4	1.4E-166	58	569	512

Status

Unreviewed

Ensembl Protein

ENSPPYP00000001346

UniProt Accession

H2N6T0;

Protein Name

Protein Synonyms/Alias

Gene Name

CDC7

Gene Synonyms/Alias

CDC7;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPPYG00000001162	ENSPPYP00000001346	ENSPPYT00000001391

Organism

Pongo abelii

Functional Description

Protein Length

574

Protein Sequence
(FASTA)

MEASLGIQMD EPMAFSPQRD RFQAEGSSKK NEQNFKLAGV KKDIEKLYEA VPQLSNVFKI 60

KDKIGEGTFS SVYLATAQLQ VGPEEKIALK HLIPTSHPIR IAAELQCLTV AGGQDNVMGV 120

KYCFRKNDHV VIAMPYLEHE SFLDILNSLS FQEVREYMFN LFKALKRIHQ FGIVHRDVKP 180

SNFLYNRRLK KYALVDFGLA QGTHDTKIEL LKFVQSEAQQ ERCSQHKSHI ITGNKIPLSG 240

PVPKELDQQS TTKASVKRPY TNAQIQIKQG KDGKEGSVGL SVQRSVFGER NFNIHSSISH 300

ESPAVKLMKQ SKTVDVLSRK LATKKKAIST KVMNSGVMRK TASSCPASLT CDCYATDKVC 360

SICLSRRQQV APRAGTPGFR APEVLTKCPN QTTAIDMWSA GVIFLSLLSG RYPFYKASDD 420

LTALAQIMTI RGSRETIQAA KTFGKSILCS KEVPAQDLRK LCERLRGMDS NTPKLTSDVQ 480

GHASHQPAIS EKTDHKASHL IQTPPGQYSG NSLKKGDSNS CEHCFDEYNT NLEGWNEVPD 540

EAYDLLDKLL DLNPASRITA EEALWHPFFK DMSL 574

Nucleotide Sequence
(FASTA)

ATGGAGGCGT CTTTGGGGAT TCAGATGGAT GAGCCAATGG CTTTTTCTCC CCAGCGTGAC 60

CGGTTTCAGG CTGAAGGCTC TTCAAAAAAA AACGAGCAGA ATTTTAAACT TGCAGGTGTT 120

AAAAAAGATA TTGAGAAGCT TTATGAAGCT GTACCACAGC TTAGTAATGT GTTTAAGATT 180

AAGGACAAAA TTGGAGAAGG CACTTTCAGC TCTGTTTATT TGGCCACAGC ACAGTTACAA 240

GTAGGACCTG AAGAGAAAAT TGCTCTAAAA CACTTGATTC CAACAAGTCA TCCTATAAGA 300

ATTGCAGCTG AACTTCAGTG CCTAACAGTG GCTGGGGGGC AAGATAATGT CATGGGAGTT 360

AAATACTGCT TTAGGAAGAA TGATCATGTA GTTATTGCTA TGCCATATCT GGAGCATGAG 420

TCGTTTTTGG ACATTTTGAA TTCTCTTTCC TTTCAAGAAG TACGGGAATA TATGTTTAAT 480

CTGTTCAAAG CTTTGAAACG CATTCATCAG TTTGGTATTG TTCACCGTGA TGTTAAGCCC 540

AGCAATTTTT TATATAATAG GCGCTTGAAA AAGTATGCCT TGGTAGACTT TGGTTTGGCC 600

CAAGGAACCC ATGATACGAA AATAGAGCTT CTTAAATTTG TCCAGTCTGA AGCTCAGCAG 660

GAAAGGTGTT CACAACACAA ATCCCACATA ATCACAGGAA ACAAGATTCC ATTGAGTGGC 720

CCAGTACCTA AGGAGCTGGA TCAGCAGTCC ACCACAAAAG CTTCTGTTAA AAGACCCTAC 780

ACAAATGCAC AAATTCAGAT TAAACAAGGA AAAGACGGAA AGGAGGGATC TGTAGGCCTT 840

TCTGTCCAGC GCTCTGTTTT TGGAGAAAGA AATTTCAATA TACACAGCTC CATTTCACAT 900

GAGAGCCCTG CAGTGAAACT CATGAAGCAG TCAAAGACTG TGGATGTACT GTCTAGAAAG 960

TTAGCAACAA AAAAGAAGGC TATTTCTACA AAAGTTATGA ATAGTGGTGT GATGAGGAAA 1020

ACTGCCAGTT CTTGCCCAGC TAGCCTGACC TGTGACTGCT ATGCAACAGA TAAAGTTTGT 1080

AGTATTTGCC TTTCAAGGCG TCAGCAGGTT GCCCCGAGGG CAGGTACACC AGGATTCAGA 1140

GCACCAGAGG TCTTGACAAA GTGCCCCAAT CAAACTACAG CAATTGACAT GTGGTCTGCA 1200

GGTGTCATAT TTCTTTCTTT GCTTAGTGGA CGATATCCAT TTTATAAAGC AAGTGATGAT 1260

TTAACTGCTT TGGCCCAAAT TATGACAATT AGGGGATCCA GAGAAACTAT CCAAGCTGCT 1320

AAAACTTTTG GGAAATCAAT ATTATGTAGC AAAGAAGTTC CAGCACAAGA CTTGAGAAAA 1380

CTCTGTGAGA GACTCAGGGG TATGGATTCT AACACTCCCA AGTTAACAAG TGATGTACAA 1440

GGGCATGCTT CTCATCAACC AGCTATTTCA GAGAAGACTG ACCATAAAGC TTCTCACCTC 1500

ATACAGACAC CTCCAGGACA ATACTCAGGG AATTCACTTA AAAAGGGGGA TAGTAATAGC 1560

TGTGAGCATT GTTTTGATGA GTATAATACC AATTTAGAAG GCTGGAATGA GGTACCCGAT 1620

GAAGCTTATG ACCTGCTTGA TAAACTTCTA GATCTAAATC CAGCTTCAAG AATAACAGCA 1680

GAAGAAGCTT TGTGGCATCC ATTTTTTAAA GATATGAGCT TGTGA 1725

Domain Profile

S: 1     fkikdkiGeGtfssvylataqleegleekialkhliptshPeriaaeLelltvlgGqenv  60

         fkikdkiGeGtfssvylataql++g+eekialkhliptshP+riaaeL++ltv+gGq+nv

Q: 58    FKIKDKIGEGTFSSVYLATAQLQVGPEEKIALKHLIPTSHPIRIAAELQCLTVAGGQDNV  117

         9***********************************************************

S: 61    vglkecfrkndsvvivlpylehesfldllrslsfqevreYlrnLlvalkrvhkfgivhrD  120

         +g+k+cfrknd+vvi++pylehesfld+l+slsfqevreY++nL++alkr+h+fgivhrD

Q: 118   MGVKYCFRKNDHVVIAMPYLEHESFLDILNSLSFQEVREYMFNLFKALKRIHQFGIVHRD  177

         ************************************************************

S: 121   vkpsnfLynrrlkkfaLvDfGLaq..............seaqkeecsrn..........l  156

         vkpsnfLynrrlkk+aLvDfGLaq              seaq+e+cs+           +

Q: 178   VKPSNFLYNRRLKKYALVDFGLAQgthdtkiellkfvqSEAQQERCSQHkshiitgnkiP  237

         ************************************************999********9

S: 157   lsaavekevd..................................................  166

         ls++v+ke+d

Q: 238   LSGPVPKELDqqsttkasvkrpytnaqiqikqgkdgkegsvglsvqrsvfgernfnihss  297

         ************************************************************

S: 167   ....................................................tcdcygtd  174

                                                             tcdcy+td

Q: 298   ishespavklmkqsktvdvlsrklatkkkaistkvmnsgvmrktasscpaslTCDCYATD  357

         ************************************************************

S: 175   kvcsvclsrrqqvanraGtpGfraPevLlkipdqttaiDiwsaGvilLsllsgryPffka  234

         kvcs+clsrrqqva+raGtpGfraPevL+k+p+qttaiD+wsaGvi+LsllsgryPf+ka

Q: 358   KVCSICLSRRQQVAPRAGTPGFRAPEVLTKCPNQTTAIDMWSAGVIFLSLLSGRYPFYKA  417

         ************************************************************

S: 235   sddlealaeivtilGsreiikaakafgksvllskevp.......................  271

         sddl+ala+i+ti+Gsre+i+aak+fgks+l+skevp

Q: 418   SDDLTALAQIMTIRGSRETIQAAKTFGKSILCSKEVPaqdlrklcerlrgmdsntpklts  477

         ************************************************************

S: 272   .......................................dsdsye...............  277

                                                ds+s+e

Q: 478   dvqghashqpaisektdhkashliqtppgqysgnslkkgDSNSCEhcfdeyntnlegwne  537

         ***************************************888888888999999999999

S: 278   .PdeaydlldkllelnPakritaeealkhpff  308

          Pdeaydlldkll+lnPa+ritaeeal hpff

Q: 538   vPDEAYDLLDKLLDLNPASRITAEEALWHPFF  569

         *******************************8

Domain Sequence
(FASTA)

FKIKDKIGEG TFSSVYLATA QLQVGPEEKI ALKHLIPTSH PIRIAAELQC LTVAGGQDNV 60

MGVKYCFRKN DHVVIAMPYL EHESFLDILN SLSFQEVREY MFNLFKALKR IHQFGIVHRD 120

VKPSNFLYNR RLKKYALVDF GLAQGTHDTK IELLKFVQSE AQQERCSQHK SHIITGNKIP 180

LSGPVPKELD QQSTTKASVK RPYTNAQIQI KQGKDGKEGS VGLSVQRSVF GERNFNIHSS 240

ISHESPAVKL MKQSKTVDVL SRKLATKKKA ISTKVMNSGV MRKTASSCPA SLTCDCYATD 300

KVCSICLSRR QQVAPRAGTP GFRAPEVLTK CPNQTTAIDM WSAGVIFLSL LSGRYPFYKA 360

SDDLTALAQI MTIRGSRETI QAAKTFGKSI LCSKEVPAQD LRKLCERLRG MDSNTPKLTS 420

DVQGHASHQP AISEKTDHKA SHLIQTPPGQ YSGNSLKKGD SNSCEHCFDE YNTNLEGWNE 480

VPDEAYDLLD KLLDLNPASR ITAEEALWHP FF 512

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0008284	; P:positive regulation of cell proliferation
GO:0033261	; P:regulation of S phase

KEGG

pon:100453876

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 2.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013