EKS-POA-00147

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-POA-00147

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/NDR	521.3	7.1E-157	38	331	294

Status

Unreviewed

Ensembl Protein

ENSPPYP00000004999

UniProt Accession

H2NGV3;

Protein Name

Protein Synonyms/Alias

Gene Name

STK38L

Gene Synonyms/Alias

STK38L;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPPYG00000004379	ENSPPYP00000004999	ENSPPYT00000005196

Organism

Pongo abelii

Functional Description

Protein Length

412

Protein Sequence
(FASTA)

MEEEGLADEE KKLRRSQHAR KETEFLRLKR TRLGLDDFES LKVIGRGAFG EVRLVQKKDT 60

GHIYAMKILR KADMLEKEQV AHIRAERDIL VEADGAWVVK MFYSFQDKRN LYLIMEFLPG 120

GDMMTLLMKK DTLTEEETQF YISETVLAID AIHQLGFIHR DIKPDNLLLD AKGHVKLSDF 180

GLCTGLKKAH RTEFYRNLTH NPPSDFSFQN MNSKRKAETW KKNRRQLAYS TVGTPDYIAP 240

EVFMQTGYNK LCDWWSLGVI MYEMLIGYPP FCSETPQETY RKVMNWKETL VFPPEVPISE 300

KAKDLILRFC IDSENRIGNS GVEEIKGHPF FEGVDWEHIR ERPAAIPIEI KSIDDTSNFD 360

DFPESDILQP VPNTTEPDYK SKDWVFLNYT YKRFEGLTQR GSIPTYMKAG KL 412

Nucleotide Sequence
(FASTA)

ATGGAAGAAG AAGGATTAGC AGATGAAGAG AAAAAGTTAC GTCGATCACA ACACGCTCGC 60

AAAGAAACAG AGTTCTTACG GCTCAAAAGG ACCAGACTTG GCTTGGATGA CTTTGAGTCT 120

CTGAAAGTTA TAGGAAGAGG AGCTTTTGGA GAGGTGCGGT TGGTCCAGAA GAAAGATACA 180

GGCCATATCT ATGCAATGAA GATATTGAGA AAGGCTGATA TGCTTGAAAA AGAGCAGGTG 240

GCCCATATCC GAGCAGAAAG AGATATTTTG GTAGAAGCAG ATGGTGCCTG GGTGGTGAAG 300

ATGTTTTACA GCTTTCAGGA TAAGAGGAAT CTTTATCTAA TCATGGAATT TCTCCCTGGA 360

GGTGACATGA TGACATTGCT AATGAAGAAA GACACCTTGA CAGAAGAGGA AACACAGTTC 420

TACATTTCAG AGACTGTTCT GGCAATAGAT GCGATCCACC AGTTGGGTTT CATCCATCGG 480

GATATTAAGC CAGACAACCT TTTATTGGAT GCCAAGGGTC ATGTAAAATT ATCTGATTTT 540

GGTTTATGTA CGGGATTAAA GAAAGCTCAC AGGACTGAAT TTTATAGAAA TCTCACACAC 600

AACCCACCAA GTGACTTCTC ATTTCAGAAT ATGAACTCAA AGAGGAAAGC AGAAACTTGG 660

AAGAAGAACA GGAGACAACT GGCATATTCC ACAGTTGGGA CACCAGATTA CATTGCTCCA 720

GAAGTATTCA TGCAGACTGG TTACAACAAA TTGTGTGACT GGTGGTCTTT GGGAGTGATT 780

ATGTATGAAA TGCTAATAGG ATATCCACCT TTCTGCTCTG AAACACCTCA AGAAACATAC 840

AGAAAAGTGA TGAACTGGAA AGAAACTCTG GTATTTCCTC CAGAGGTACC TATATCTGAG 900

AAAGCCAAGG ACTTAATTCT CAGATTTTGT ATTGATTCTG AAAACAGAAT TGGAAATAGT 960

GGAGTAGAAG AAATAAAAGG TCATCCCTTT TTTGAAGGTG TCGACTGGGA GCACATAAGG 1020

GAAAGGCCAG CAGCAATCCC TATAGAAATC AAAAGCATTG ATGATACTTC AAATTTTGAT 1080

GACTTTCCTG AATCTGATAT TTTACAACCA GTGCCAAATA CCACAGAACC GGACTACAAA 1140

TCCAAAGACT GGGTTTTTCT CAATTATACC TATAAAAGGT TTGAAGGGTT GACTCAACGT 1200

GGCTCTATCC CCACCTACAT GAAAGCTGGG AAATTATGA 1239

Domain Profile

S: 1     feklkvigkGafGevrlvrkkdtkevyalkilrkkdllkknqvahvkaerdilaeadsew  60

         fe+lkvig+GafGevrlv+kkdt+++ya+kilrk+d+l+k+qvah++aerdil+ead +w

Q: 38    FESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKADMLEKEQVAHIRAERDILVEADGAW  97

         899*********************************************************

S: 61    vvklyysfqdkenlylvmeylPGGdlmtllikkeilkeelarfyiaelvlavesvhklGf  120

         vvk++ysfqdk+nlyl+me+lPGGd+mtll+kk++l+ee+++fyi+e+vla++++h+lGf

Q: 98    VVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYISETVLAIDAIHQLGF  157

         ************************************************************

S: 121   ihrdlkPdnllidakGhikltdfGlctGlkkthrseyykelekakeddleaseelkvler  180

         ihrd+kPdnll+dakGh+kl+dfGlctGlkk+hr+e+y++l+++ ++d+++++  ++ +

Q: 158   IHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNLTHNPPSDFSFQNMNSKRKA  217

         *************************************************65555555555

S: 181   rkkkknrrllayslvGtpdyiapevlekkgynklcdwWslGvilyemlvGypPflaetpq  240

            kknrr+lays+vGtpdyiapev++++gynklcdwWslGvi+yeml+GypPf++etpq

Q: 218   ETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQ  277

         555*********************************************************

S: 241   etykkvinwketlkfpeevelseeakdlierliadaekrlgkkGvdeikkhpff  294

         ety+kv+nwketl fp+ev++se+akdli r+++d+e+r+g++Gv+eik hpff

Q: 278   ETYRKVMNWKETLVFPPEVPISEKAKDLILRFCIDSENRIGNSGVEEIKGHPFF  331

         *****************************************************9

Domain Sequence
(FASTA)

FESLKVIGRG AFGEVRLVQK KDTGHIYAMK ILRKADMLEK EQVAHIRAER DILVEADGAW 60

VVKMFYSFQD KRNLYLIMEF LPGGDMMTLL MKKDTLTEEE TQFYISETVL AIDAIHQLGF 120

IHRDIKPDNL LLDAKGHVKL SDFGLCTGLK KAHRTEFYRN LTHNPPSDFS FQNMNSKRKA 180

ETWKKNRRQL AYSTVGTPDY IAPEVFMQTG YNKLCDWWSL GVIMYEMLIG YPPFCSETPQ 240

ETYRKVMNWK ETLVFPPEVP ISEKAKDLIL RFCIDSENRI GNSGVEEIKG HPFF 294

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Canis familiaris"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>

Gene Ontology

GO:0015629	; C:actin cytoskeleton
GO:0005737	; C:cytoplasm
GO:0005634	; C:nucleus
GO:0005886	; C:plasma membrane
GO:0005524	; F:ATP binding
GO:0000287	; F:magnesium ion binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007243	; P:intracellular protein kinase cascade
GO:0051128	; P:regulation of cellular component organization

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013