EKS-POA-00278

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-POA-00278

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	334.4	5.8E-100	204	505	302

Status

Unreviewed

Ensembl Protein

ENSPPYP00000005223

UniProt Accession

H2NHH1;

Protein Name

Protein Synonyms/Alias

Gene Name

AMHR2

Gene Synonyms/Alias

AMHR2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPPYG00000004580	ENSPPYP00000005223	ENSPPYT00000005427

Organism

Pongo abelii

Functional Description

Protein Length

573

Protein Sequence
(FASTA)

MLGSLGLWAL LPTAVEAPPN RRTCVFFEAP GVRGSTKTLG ELLDTGTELP RAIRCLYSRC 60

CFGIWNLTQD RAQVEMQGCR DSDEPGCESL HCDPSPRAHP SPGSTLFTCS CGTDFCNANY 120

SHLPPPGSPG TPGSQGPQAA PGESIWMALV LLGLFLLLLL LLGSIILALL QRKNYRVRGE 180

PVPEPRPDSG RDWSVELQEL PELCFSQVIR EGGHAVVWAG QLQGKLVAIK AFPPRSVAQF 240

QAERALYELP GLQHDHIVRF ITASRGGPGP LVSGPLLVLE LHPKGSLCHY LTQHTSDWGS 300

SLRMALSLAQ GLAFLHEERW QNGQYKPGIA HRDLSSQNVL IREDGSCAIG DLGLALVLPG 360

LTQPPAWTPT QPQGPAAIME AGTQRYMAPE LLDKTLDLQD WGMALRRADI YSLALLLWEI 420

LSRCPDLSPD SSPPPFQLAY EAELGNTPTS DELWALAVQE RRRPYIPSTW RCFATDPDGL 480

RELLEDCWDA DPEARLTAEC VQQRLASLAH PQESHSFPES CPRGCPPLCP EDCTSIAAPT 540

ILPCRPQRSA CHFSVQQGPC SRNPQPACTL SPV 573

Nucleotide Sequence
(FASTA)

ATGCTAGGGT CTTTGGGGCT TTGGGCATTA CTTCCCACAG CTGTGGAAGC ACCCCCAAAC 60

AGGCGAACCT GTGTGTTCTT TGAGGCCCCT GGAGTGCGGG GAAGCACAAA GACACTGGGA 120

GAGCTGCTAG ATACAGGCAC AGAGCTCCCC AGAGCTATCC GCTGCCTCTA CAGCCGCTGC 180

TGCTTTGGGA TCTGGAACCT GACCCAAGAC CGGGCACAGG TGGAAATGCA AGGATGCCGA 240

GACAGTGATG AGCCAGGCTG TGAGTCCCTC CACTGTGACC CAAGTCCCCG AGCCCACCCC 300

AGCCCTGGCT CCACTCTCTT CACCTGCTCC TGTGGCACTG ACTTCTGCAA TGCCAATTAC 360

AGCCATCTGC CTCCTCCAGG GAGTCCTGGG ACTCCTGGCT CCCAGGGTCC TCAGGCTGCC 420

CCAGGTGAGT CCATCTGGAT GGCACTGGTG CTGCTGGGGC TGTTCCTCCT CCTCCTGCTG 480

CTGCTGGGCA GCATCATCTT GGCCCTGCTA CAGCGAAAGA ACTACAGAGT GCGAGGTGAG 540

CCAGTGCCAG AGCCAAGGCC AGACTCAGGC AGGGACTGGA GTGTGGAGCT GCAGGAGCTG 600

CCCGAGCTGT GTTTCTCCCA GGTAATCCGG GAAGGAGGTC ATGCAGTGGT TTGGGCCGGG 660

CAGCTGCAAG GAAAACTGGT TGCCATCAAG GCCTTCCCAC CGAGGTCTGT GGCTCAGTTC 720

CAAGCTGAGA GAGCATTGTA CGAACTTCCA GGCCTACAGC ACGACCACAT TGTCCGATTT 780

ATCACTGCCA GCCGGGGGGG CCCTGGCCCC CTGGTCTCTG GGCCCCTGCT GGTACTGGAA 840

CTGCATCCCA AGGGCTCCCT GTGCCACTAC TTGACCCAGC ACACCAGTGA CTGGGGAAGT 900

TCCCTGCGGA TGGCACTGTC CCTGGCCCAA GGCCTGGCAT TTCTCCATGA GGAGCGCTGG 960

CAGAATGGCC AATATAAACC AGGTATTGCC CACCGAGATC TGAGCAGCCA GAATGTGCTC 1020

ATTCGGGAAG ATGGATCATG TGCCATTGGA GACCTGGGCC TTGCCTTGGT GCTCCCTGGC 1080

CTCACTCAGC CCCCTGCCTG GACCCCTACT CAACCACAAG GCCCAGCTGC CATCATGGAA 1140

GCTGGCACCC AGAGGTACAT GGCACCAGAG CTCTTGGACA AGACTCTGGA CCTACAGGAT 1200

TGGGGCATGG CCCTCCGACG AGCTGATATT TACTCTTTGG CTCTGCTCCT GTGGGAGATA 1260

CTGAGCCGCT GCCCAGATTT GAGTCCTGAC AGCAGTCCAC CACCCTTCCA ACTGGCCTAT 1320

GAGGCAGAAC TGGGCAATAC CCCTACCTCT GATGAGCTAT GGGCCTTGGC AGTGCAGGAG 1380

AGGAGGCGTC CCTACATCCC ATCCACCTGG CGCTGCTTTG CCACAGACCC TGATGGGCTG 1440

AGGGAGCTCC TAGAAGACTG TTGGGATGCA GACCCAGAAG CACGGCTGAC GGCTGAGTGT 1500

GTACAGCAGC GCCTGGCTTC CCTGGCCCAT CCTCAGGAGA GCCACTCCTT TCCAGAGAGC 1560

TGTCCACGGG GCTGCCCACC TCTCTGCCCA GAAGACTGTA CTTCAATTGC TGCCCCTACC 1620

ATCCTCCCCT GTAGGCCTCA GCGGAGTGCC TGCCACTTCA GTGTTCAGCA AGGCCCTTGT 1680

TCCAGGAATC CTCAGCCTGC CTGTACCCTT TCTCCTGTGT AA 1722

Domain Profile

S: 2     klleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfiaa  61

          ++++i++G ++ Vw+++l+g+ vA+K+f+ ++ a++++E+++y+++ l+h++i++fi+a

Q: 204   CFSQVIREGGHAVVWAGQLQGKLVAIKAFPPRSVAQFQAERALYELPGLQHDHIVRFITA  263

         57899*******************************************************

S: 62    dk.keedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtk  120

          +     +++  llv+e+h+kgsL++yL+++t+d+ ++lr+alsla+Gla+LHee ++++

Q: 264   SRgGPGPLVSGPLLVLELHPKGSLCHYLTQHTSDWGSSLRMALSLAQGLAFLHEE-RWQN  322

         **88999************************************************.8999

S: 121   gkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekee........ldlaansqvG  172

         g++Kp iaHRDl+s+N+l+++d++c+i+DlGLal l   ++         +  aa++++G

Q: 323   GQYKPGIAHRDLSSQNVLIREDGSCAIGDLGLALVLPGLTQPpawtptqpQGPAAIMEAG  382

         **********************************87776666688888888899******

S: 173   tkRYmaPEvleealnlkdfe.afkraDvYslgLvlWEvasRcee..vdeeveeyklpfee  229

         t+RYmaPE+l+++l+l+d+  a++raD+Ysl+L+lWE++sRc +  +d++ ++++l++e+

Q: 383   TQRYMAPELLDKTLDLQDWGmALRRADIYSLALLLWEILSRCPDlsPDSSPPPFQLAYEA  442

         *******************99**********************99999************

S: 230   vvgsdPsleemkevvvekklrPkipeawkkke.alkelsklleecWdadpeaRltalrvk  288

         ++g++P+ +e++++ v+++ rP ip++w++ + + + l++lle+cWdadpeaRlta++v+

Q: 443   ELGNTPTSDELWALAVQERRRPYIPSTWRCFAtDPDGLRELLEDCWDADPEARLTAECVQ  502

         ******************************98789*************************

S: 289   krl  291

+rl

Q: 503   QRL  505

Domain Sequence
(FASTA)

CFSQVIREGG HAVVWAGQLQ GKLVAIKAFP PRSVAQFQAE RALYELPGLQ HDHIVRFITA 60

SRGGPGPLVS GPLLVLELHP KGSLCHYLTQ HTSDWGSSLR MALSLAQGLA FLHEERWQNG 120

QYKPGIAHRD LSSQNVLIRE DGSCAIGDLG LALVLPGLTQ PPAWTPTQPQ GPAAIMEAGT 180

QRYMAPELLD KTLDLQDWGM ALRRADIYSL ALLLWEILSR CPDLSPDSSP PPFQLAYEAE 240

LGNTPTSDEL WALAVQERRR PYIPSTWRCF ATDPDGLREL LEDCWDADPE ARLTAECVQQ 300

RL 302

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Microcebus murinus"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0042562	; F:hormone binding
GO:0005024	; F:transforming growth factor beta-activated receptor activity
GO:0007548	; P:sex differentiation
GO:0007178	; P:transmembrane receptor protein serine/threonine kinase signaling pathway

KEGG

pon:100441106

;

InterPros

IPR000472	; Activin_rcpt.
IPR015771	; Anti-muellerian_hrmn_rcpt_II.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.

Pfam

PF01064	; Activin_recp; 1.
PF00069	; Pkinase; 1.

SMARTs

Prosites

PS50011

; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013