EKS-POA-00284
Eukaryotic Protein Kinase & Protein Phosphatase Database
TagContent
EKPD IDEKS-POA-00284
Classification
Group/FamilyScoreE-ValueStartEndDomain Length
Other/BUB319.51.5E-957531017265
StatusUnreviewed
Ensembl ProteinENSPPYP00000007185
UniProt AccessionH2NMT8;
Protein Name
Protein Synonyms/Alias
Gene NameBUB1B
Gene Synonyms/Alias BUB1B;
Ensembl Information
Ensembl Gene IDEnsembl Protein IDEnsembl Transcript ID
ENSPPYG00000006345ENSPPYP00000007185ENSPPYT00000007484
OrganismPongo abelii
Functional Description
Protein Length1050
Protein Sequence
(FASTA)
MAAVKKEGGA LSEAMSLEGD EWELSKENVQ PLRQGRIMST LQGALAQESA CNNTLQQQKR 60
AFEYEIRFYT GNDPLDVWDR YISWTEQNYP QGGKESNMST LLERAVEALQ GEKRYYSDPR 120
FLNLWLKLGR LCNEPLDMYS YLHNQGIGVS LAQFYISWAE EYEARENFRK ADAIFQEGIQ 180
QKAEPLERLQ SQHRQFQARV SRQTLLALEK EEEEEVFESS VPQRSTLAEL KSKGKKTARA 240
PIIRVGGALK APSQNRGLQN PFPQQMQSNS RITVFDENAD EASTAELSKP TVQPWIAPPV 300
PRAKENELQA GPWNTGRSLE HRPRGNTASL IAVPAVLPSF TPYVEETAQQ PVMTPCKIEP 360
SINHILSTRK PGKEEGDPLQ RVQSHQQASE EKKEKMMYCK EKIYAGVGEF SFEEIRAEVF 420
RKKLKEQREA ELLTSAEKRA EMQKQIEEME KKLKEIQTTQ QERTGDQQEE TMPTKETTKL 480
RIASGSQKIP GMTLSSSVCQ VNSCARETSL VENIWQEQPH SKGPSIPFSI FDEFLLSEKK 540
NKSPPADPPQ VLAQRRPLAV LKTSESITSN EDVSPDVCDE FTGIEPLSED AIITGFRNVT 600
ICPNPEDTCD FARAARFVST PFHEIMSLKD LPSDPERLLP EEDLDVKTSE DQQTACGTIY 660
SQTLSIKKLS PIIEDSREAT HSSGFSGSSA SVASTSSIKC LQIPEKLELT NETSENPTQS 720
PWCSQYRRQL LKSLPELSAS AELCIEDRPM PKLEIEKEIE LGNEDYCIKR EYLICEDYKL 780
FWVAPRNSAE LTVIKVSSQP VPWDFYINLK LKERLNEAFD HLCSCYQYQD GCIVWHQYIN 840
CFTLQDLLQH SEYITHEITV LIIYNLLTIV EKLHKAEIVH GDLSPRSLIL RNRIHDPYDC 900
NKNNQALKIV DFSYSVDLRV QLDVFTLSGF RTVQILEGQK ILANCSSPYQ VDLFGIADLA 960
HLLLFKEHLQ VFWDGSFWKL SQNISELKDG ELWNKFFVRI LNANDEATVS VLGELAAEMN 1020
GVFDTTFQSH LNKALWKVGK LTSPGALLFQ 1050
Nucleotide Sequence
(FASTA)
ATGGCGGCGG TGAAGAAGGA AGGGGGTGCT CTGAGTGAAG CCATGTCCCT GGAGGGAGAT 60
GAATGGGAAC TGAGTAAAGA AAATGTACAA CCTTTAAGGC AAGGGCGGAT CATGTCCACA 120
CTTCAGGGAG CACTGGCACA AGAATCTGCC TGTAACAATA CTCTTCAGCA GCAGAAACGG 180
GCATTTGAAT ATGAAATTCG ATTTTACACT GGAAATGACC CTCTGGATGT TTGGGATAGG 240
TATATCAGCT GGACAGAGCA GAACTATCCT CAAGGTGGGA AGGAGAGTAA TATGTCAACG 300
TTATTAGAAA GAGCTGTAGA AGCACTACAA GGAGAAAAAC GATATTATAG TGATCCTCGA 360
TTTCTCAATC TCTGGCTTAA ATTAGGGCGT TTATGCAATG AGCCTTTGGA TATGTACAGT 420
TACTTGCACA ACCAAGGGAT TGGTGTTTCA CTTGCTCAGT TCTATATCTC ATGGGCAGAA 480
GAATATGAAG CTAGAGAAAA CTTTAGGAAA GCAGATGCGA TATTTCAGGA AGGGATTCAA 540
CAGAAGGCTG AACCACTAGA AAGACTACAG TCCCAACACC GACAATTCCA AGCTCGAGTG 600
TCTCGACAAA CTCTGTTGGC ACTTGAGAAA GAAGAAGAGG AGGAAGTTTT TGAGTCTTCT 660
GTACCACAAC GAAGCACACT AGCTGAACTA AAGAGCAAAG GGAAAAAGAC AGCAAGAGCT 720
CCAATCATCC GTGTAGGAGG TGCTCTCAAG GCTCCAAGCC AGAACAGAGG ACTCCAAAAT 780
CCATTTCCTC AACAGATGCA AAGTAATAGC AGAATTACTG TTTTTGATGA AAATGCTGAT 840
GAGGCTTCTA CAGCAGAGTT GTCTAAGCCT ACAGTCCAGC CATGGATAGC ACCCCCCGTG 900
CCCAGGGCCA AAGAGAATGA GCTGCAAGCA GGCCCTTGGA ACACAGGCAG GTCCTTGGAA 960
CACAGGCCTC GTGGCAATAC AGCTTCACTG ATAGCTGTAC CCGCTGTGCT TCCCAGTTTT 1020
ACTCCATATG TGGAAGAGAC TGCACAACAG CCAGTTATGA CACCATGTAA AATTGAACCT 1080
AGTATAAACC ACATCCTAAG CACCAGAAAG CCTGGAAAGG AAGAAGGAGA TCCTCTACAA 1140
AGGGTTCAGA GCCATCAGCA AGCATCTGAG GAGAAGAAAG AGAAGATGAT GTATTGTAAG 1200
GAGAAGATTT ATGCAGGAGT AGGGGAATTC TCCTTTGAAG AAATTCGGGC TGAAGTTTTC 1260
CGGAAGAAAT TAAAAGAACA AAGGGAAGCC GAGCTATTGA CCAGTGCAGA AAAGAGAGCA 1320
GAAATGCAGA AACAGATTGA AGAGATGGAG AAGAAGCTAA AAGAAATCCA AACTACTCAG 1380
CAAGAAAGAA CAGGTGATCA GCAAGAAGAG ACGATGCCTA CAAAGGAGAC AACTAAACTG 1440
CGAATTGCTT CCGGGTCTCA GAAAATACCA GGAATGACTC TATCCAGTTC TGTTTGTCAA 1500
GTAAACTCTT GTGCCAGAGA AACTTCACTT GTGGAGAACA TTTGGCAGGA ACAACCTCAT 1560
TCAAAAGGTC CCAGTATACC TTTCTCCATT TTTGATGAGT TTCTTCTTTC AGAAAAGAAG 1620
AATAAAAGTC CTCCTGCAGA TCCCCCACAA GTTTTAGCTC AACGAAGACC CCTTGCAGTT 1680
CTCAAAACCT CAGAAAGCAT CACCTCAAAT GAAGATGTGT CTCCAGATGT TTGTGATGAA 1740
TTTACAGGAA TTGAACCCTT GAGCGAGGAT GCCATTATCA CAGGCTTCAG AAATGTAACA 1800
ATTTGTCCTA ACCCAGAAGA CACTTGTGAC TTTGCCAGAG CAGCTCGTTT TGTATCCACT 1860
CCTTTTCATG AGATAATGTC CTTGAAGGAT CTCCCTTCTG ATCCTGAGAG ACTGTTACCA 1920
GAAGAGGATC TGGATGTAAA GACCTCTGAG GACCAGCAGA CAGCTTGTGG CACTATCTAC 1980
AGTCAGACTC TCAGCATCAA GAAGCTGAGC CCAATTATTG AAGACAGTCG TGAAGCCACA 2040
CACTCCTCTG GCTTCTCTGG TTCTTCTGCC TCGGTTGCAA GCACCTCCTC CATCAAATGT 2100
CTTCAAATTC CTGAGAAACT AGAACTTACT AATGAGACTT CAGAAAACCC TACTCAGTCA 2160
CCATGGTGTT CACAGTATCG CAGACAGCTA CTGAAGTCCC TACCAGAGTT AAGTGCCTCT 2220
GCAGAGTTGT GTATAGAAGA CAGACCAATG CCTAAGTTGG AAATTGAGAA GGAAATTGAA 2280
TTAGGTAATG AGGATTACTG CATTAAACGA GAATACCTAA TATGTGAAGA TTACAAGTTA 2340
TTCTGGGTGG CGCCAAGAAA CTCTGCAGAA TTAACCGTAA TAAAGGTATC TTCTCAACCT 2400
GTCCCATGGG ACTTTTATAT CAACCTCAAG TTAAAGGAAC GTTTAAATGA AGCCTTTGAT 2460
CATTTGTGCA GCTGTTATCA ATATCAAGAT GGCTGTATTG TTTGGCACCA ATATATAAAC 2520
TGCTTCACCC TTCAGGATCT TCTCCAACAC AGTGAATATA TCACCCATGA AATAACAGTG 2580
TTGATTATTT ATAACCTTTT GACAATAGTG GAGAAGCTAC ACAAAGCGGA AATAGTCCAT 2640
GGTGACTTGA GTCCAAGGAG TCTGATTCTG AGAAACAGAA TCCACGATCC CTATGATTGT 2700
AACAAGAACA ATCAAGCTTT GAAGATAGTG GACTTTTCCT ACAGTGTTGA CCTTAGGGTG 2760
CAGCTGGATG TTTTTACCCT CAGCGGCTTT CGGACTGTAC AGATCCTGGA AGGACAAAAG 2820
ATCCTGGCTA ACTGTTCTTC TCCCTACCAG GTAGACCTGT TTGGTATAGC AGATTTAGCG 2880
CATTTACTAT TGTTCAAGGA ACACCTACAG GTCTTCTGGG ATGGGTCCTT CTGGAAACTT 2940
AGCCAAAATA TTTCTGAGCT AAAAGATGGT GAATTGTGGA ATAAATTCTT TGTGCGGATT 3000
CTGAATGCCA ATGATGAGGC CACAGTGTCT GTTCTTGGGG AGCTTGCAGC AGAAATGAAT 3060
GGGGTTTTTG ACACTACATT CCAAAGTCAC CTGAACAAAG CCTTATGGAA GGTAGGGAAG 3120
TTAACTAGTC CTGGGGCTTT GCTCTTTCAG TGA 3153
Domain Profile
S: 1     leiekeigeGayakvykaeh....dsk........sgelvalKvekpansWefYIclqlk  48
         leiekei+ G++++++k+e+    d+k        s+el+++Kv++++++W+fYI+l+lk
Q: 753   LEIEKEIELGNEDYCIKREYliceDYKlfwvaprnSAELTVIKVSSQPVPWDFYINLKLK  812
         68******************999988899999999*************************
S: 49    eRlkeeellksiieissallfqdasllvleyasygtlldlinkvkevtnkvmdeelvvll  108
         eRl+e      +++++s++++qd+++++++y++++tl+dl+++++++t     +e++vl+
Q: 813   ERLNEA-----FDHLCSCYQYQDGCIVWHQYINCFTLQDLLQHSEYIT-----HEITVLI  862
         ****87.....*************************************.....*******
S: 109   ivqllkiveklHeveIiHgDlkPdnfllgnrimdkadkdkeekglkliDfgrsiDmkllp  168
         i++ll+iveklH++eI+HgDl+P++++l+nri+d++d++k++++lk++Df++s+D+++++
Q: 863   IYNLLTIVEKLHKAEIVHGDLSPRSLILRNRIHDPYDCNKNNQALKIVDFSYSVDLRVQL  922
         ************************************************************
S: 169   dgtkfkgkaktdafeciemlagkswsYqvDlfglaavihvllfgkyleviqeggswklkq  228
         d+++++g+++++++e++++la++s++YqvDlfg+a+++h+llf+++l+v+++g+ wkl+q
Q: 923   DVFTLSGFRTVQILEGQKILANCSSPYQVDLFGIADLAHLLLFKEHLQVFWDGSFWKLSQ  982
         ************************************************************
S: 229   kikrllkkelwekiferlLNisdastlpsleelve  263
         +i++l++ elw+k+f+r+LN++d++t+++l+el++
Q: 983   NISELKDGELWNKFFVRILNANDEATVSVLGELAA  1017
         ********************************986
Domain Sequence
(FASTA)
LEIEKEIELG NEDYCIKREY LICEDYKLFW VAPRNSAELT VIKVSSQPVP WDFYINLKLK 60
ERLNEAFDHL CSCYQYQDGC IVWHQYINCF TLQDLLQHSE YITHEITVLI IYNLLTIVEK 120
LHKAEIVHGD LSPRSLILRN RIHDPYDCNK NNQALKIVDF SYSVDLRVQL DVFTLSGFRT 180
VQILEGQKIL ANCSSPYQVD LFGIADLAHL LLFKEHLQVF WDGSFWKLSQ NISELKDGEL 240
WNKFFVRILN ANDEATVSVL GELAA 265
KeywordComplete proteome; Reference proteome.
Sequence SourceEnsembl
Orthology
Ortholog group
Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>
EKS-AIM-00274
EKS-ANC-00283
EKS-BOT-00292
EKS-CAJ-00298
EKS-CAF-00298
EKS-CAP-00327
EKS-DAR-00641
EKS-EQC-00283
EKS-FEC-00278
EKS-GAG-00245
EKS-HOS-00298
EKS-ICT-00276
EKS-LOA-00302
EKS-MAM-00295
EKS-MEG-00234
EKS-MOD-00287
EKS-MUM-00323
EKS-MUP-00289
EKS-MYL-00294
EKS-NOL-00269
EKS-ORA-00257
EKS-ORC-00274
EKS-OTG-00298
EKS-PAT-00277
EKS-PES-00260
EKS-PEM-00161
EKS-RAN-00308
EKS-SAH-00274
EKS-SUS-00257
EKS-TAG-00308
EKS-TUT-00048
EKS-XET-00365
Gene Ontology
GO:0000940; C:condensed chromosome outer kinetochore
GO:0048471; C:perinuclear region of cytoplasm
GO:0005524; F:ATP binding
GO:0004672; F:protein kinase activity
GO:0007091; P:mitotic metaphase/anaphase transition
GO:0034501; P:protein localization to kinetochore
KEGG
pon:100455824;
InterPros
IPR011009; Kinase-like_dom.
IPR013212; Mad3_BUB1_I.
IPR000719; Prot_kinase_cat_dom.
IPR015661; Ser/Thr_kinase_Bub1.
Pfam
PF08311; Mad3_BUB1_I; 1.
PF00069; Pkinase; 1.
SMARTs
SM00777; Mad3_BUB1_I; 1.
Prosites
PS51489; BUB1_N; 1.
Prints
Created Date20-Feb-2013