EKS-POA-00211

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-POA-00211

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NKF1	409.5	5.6E-123	53	313	261

Status

Unreviewed

Ensembl Protein

ENSPPYP00000008162

UniProt Accession

H2NQH7;

Protein Name

Serine/threonine-protein kinase SBK1

Protein Synonyms/Alias

SH3-binding kinase 1;

Gene Name

SBK1

Gene Synonyms/Alias

SBK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPPYG00000007219	ENSPPYP00000008162	ENSPPYT00000008499

Organism

Pongo abelii

Functional Description

Protein Length

426

Protein Sequence
(FASTA)

MSMGCPEPEP PRSLTCCGPG TAPGPGAGVP LLTEDMQALT LRTLAASDVT KHYELVRELG 60

KGTYGKVDLV VYKGTGTKMA LKFVNKSKTK LKNFLREVSI TNSLSSSPFI IKVFDVVFET 120

EDCYVFAQEY APAGDLFDII PPQVGLPEDT VKRCVQQLGL ALDFMHGRQL VHRDIKPENV 180

LLFDRECRRV KLADFGMTRR VGCRVKRVSG TIPYTAPEVC QAGRADGLAV DTGVDVWAFG 240

VLIFCVLTGN FPWEAASGAD AFFEEFVRWQ RGRLPGLPSQ WRRFTEPALR MFQRLLALEP 300

ERRGPAKEVF RFLKHELTSE LRRRPSHRAR KPPGDRPPAA GPLRLEAPGP LKRTVLTESG 360

SGSRPAPPAV GSVPVPVPVP VPVPVPVPVP VPEPGLAPPG PPGRTDGRAD KSKGQVVLAT 420

AIEICV 426

Nucleotide Sequence
(FASTA)

ATGAGCATGG GCTGCCCAGA GCCTGAGCCG CCCCGCTCCC TGACCTGCTG TGGGCCGGGG 60

ACTGCCCCTG GGCCTGGTGC CGGTGTGCCC CTTCTCACTG AAGACATGCA GGCCCTGACT 120

CTCCGCACAC TGGCCGCCAG CGACGTCACC AAGCACTACG AACTAGTCCG GGAGCTGGGC 180

AAAGGCACCT ATGGGAAGGT TGACCTGGTG GTCTACAAGG GCACAGGCAC AAAAATGGCA 240

CTGAAGTTTG TGAACAAGAG CAAAACCAAG CTGAAGAACT TCCTGCGGGA GGTGAGCATC 300

ACCAACAGCC TCTCCTCCAG CCCCTTCATC ATCAAGGTCT TTGACGTGGT CTTTGAGACA 360

GAGGACTGCT ACGTCTTTGC CCAGGAGTAC GCACCTGCTG GGGACCTGTT TGACATCATC 420

CCTCCCCAGG TGGGGCTCCC TGAGGACACG GTGAAGCGCT GCGTGCAGCA GCTGGGCCTG 480

GCGCTGGACT TCATGCACGG GCGGCAGTTG GTGCACCGCG ACATCAAGCC CGAGAACGTG 540

CTGCTGTTCG ACCGCGAGTG CCGCCGCGTA AAGCTGGCCG ACTTCGGCAT GACGCGCCGC 600

GTGGGCTGCC GCGTCAAGCG CGTGAGCGGC ACCATCCCTT ACACGGCGCC TGAGGTGTGC 660

CAGGCGGGCC GCGCCGACGG GTTGGCGGTG GACACGGGCG TGGACGTGTG GGCCTTCGGC 720

GTGCTCATCT TCTGCGTGCT CACCGGCAAC TTCCCGTGGG AGGCGGCGTC GGGCGCCGAC 780

GCCTTCTTCG AGGAGTTCGT GCGCTGGCAG CGGGGCCGCC TGCCGGGGCT GCCTTCGCAG 840

TGGCGCCGCT TCACCGAGCC CGCGCTGCGC ATGTTCCAGC GCCTACTGGC CCTGGAGCCC 900

GAGCGCCGCG GCCCGGCCAA GGAGGTGTTC CGCTTCCTCA AGCACGAGCT CACGTCCGAG 960

CTGCGCCGCC GGCCCTCGCA CCGCGCGCGC AAGCCCCCCG GGGACCGCCC GCCCGCCGCC 1020

GGGCCACTGC GCCTCGAGGC GCCCGGGCCG CTCAAGCGGA CGGTGCTGAC CGAGAGCGGC 1080

AGCGGCTCCC GGCCCGCGCC CCCTGCCGTC GGGTCGGTGC CCGTGCCCGT GCCGGTGCCG 1140

GTGCCGGTGC CCGTGCCCGT GCCGGTGCCT GTGCCCGAGC CCGGCTTGGC TCCCCCGGGG 1200

CCCCCCGGCC GGACCGACGG CCGCGCGGAC AAGAGCAAAG GGCAGGTGGT GCTGGCCACG 1260

GCCATCGAGA TCTGCGTCTG A 1281

Domain Profile

S: 1     yelvrklgeGsfgkvlLvehrqsgtkvalKllpkektklkdFlrEfsvglslsshsaivk  60

         yelvr+lg+G++gkv+Lv ++++gtk+alK+++k+ktklk+FlrE+s+++slss+++i+k

Q: 53    YELVRELGKGTYGKVDLVVYKGTGTKMALKFVNKSKTKLKNFLREVSITNSLSSSPFIIK  112

         9***********************************************************

S: 61    tydvaletadayvFaqEyaplgdLaeaiqekvGlpeaavkrvvaqlasAldflHsrnlvh  120

         ++dv++et+d+yvFaqEyap+gdL+++i+++vGlpe++vkr+v+ql+ Aldf+H+r+lvh

Q: 113   VFDVVFETEDCYVFAQEYAPAGDLFDIIPPQVGLPEDTVKRCVQQLGLALDFMHGRQLVH  172

         ************************************************************

S: 121   rdlKpenvLvfdpdcsrvkltDfGltrkkgslvkkkeevipytapelcelvkeeklkvdp  180

         rd+KpenvL+fd++c+rvkl+DfG+tr++g++vk+++ +ipytape+c++ ++++l+vd+

Q: 173   RDIKPENVLLFDRECRRVKLADFGMTRRVGCRVKRVSGTIPYTAPEVCQAGRADGLAVDT  232

         ************************************************************

S: 181   svDvWalGvllfvvltgkfPWdkasleadpfyeeflkwqkrklrklPkkfkrlsekalrl  240

         +vDvWa+Gvl+f+vltg+fPW++a + ad+f+eef++wq+++l+ lP++++r++e+alr+

Q: 233   GVDVWAFGVLIFCVLTGNFPWEAA-SGADAFFEEFVRWQRGRLPGLPSQWRRFTEPALRM  291

         ************************.9**********************************

S: 241   lkklldlepedrskakevakfl  262

         +++ll+lepe+r +akev++fl

Q: 292   FQRLLALEPERRGPAKEVFRFL  313

         *******************997

Domain Sequence
(FASTA)

YELVRELGKG TYGKVDLVVY KGTGTKMALK FVNKSKTKLK NFLREVSITN SLSSSPFIIK 60

VFDVVFETED CYVFAQEYAP AGDLFDIIPP QVGLPEDTVK RCVQQLGLAL DFMHGRQLVH 120

RDIKPENVLL FDRECRRVKL ADFGMTRRVG CRVKRVSGTI PYTAPEVCQA GRADGLAVDT 180

GVDVWAFGVL IFCVLTGNFP WEAASGADAF FEEFVRWQRG RLPGLPSQWR RFTEPALRMF 240

QRLLALEPER RGPAKEVFRF L 261

Keyword

ATP-binding; Complete proteome; Cytoplasm; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Petromyzon marinus"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

pon:100452279

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR016234	; Ser/Thr_kinase_Sbk1.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013