EPS-POA-00033

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-POA-00033

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	192.9	8.8E-57	820	1066	247

Status

Unreviewed

Ensembl Protein

ENSPPYP00000008499

UniProt Accession

H2NRE8;

Protein Name

Protein Synonyms/Alias

Gene Name

PHLPP2

Gene Synonyms/Alias

PHLPP2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPPYG00000007526	ENSPPYP00000008499	ENSPPYT00000008846

Organism

Pongo abelii

Functional Description

Protein Length

1358

Protein Sequence
(FASTA)

MGEVEPGPAG PLDPPEPPEA PASRRPGGIR FLKRNMKRNG SRNCLNRRSR FGSRERDWLR 60

EDVKRGCVYL YGADTTTATT TTTTSSSTSS SSSSSDLHLV LCTVETPASE ICAGEGRESL 120

YLQLHGDLVR RLEPTERPLQ IVYDYLSRLG FDDPVRIQEE ATNPDLGCMI RFYGEKPCHM 180

DHLDRILLSG IYNVRKGKTQ LHKWAERLVV LCGTCLIVSS VKDCQTGKMH ILPLVGGKIE 240

EVKRRQYSLA FSSAGAQAQT YHVSFETLAE YQRWQRQASK VVSQRISTVD LSCYSLEEVP 300

EHLFYSQDIT YLNLRHNFMQ LERPGGLDTL YKFSQLKGLN LSHNKLGLFP ILLCEISTLT 360

ELNVSCNGFR DLPSQIGNLL NLQTLCLDGN FLTTLPEELG NLQQLSSLGI SFNNFSQIPE 420

VYEKLTMLDR VVMAGNCLEV LNLGVLNRMN HIKHVDLRMN HLKTMVIENL EGNKHITHVD 480

LRDNRLTDLD LSSLCSLEQL HCGRNQLREL TLSGFSLRTL YASSNRLTAV NIYPVPSLLT 540

SLDLSRNLLE CVPDWACEAK KIEVLDVSYN LLTEVPMRIL SSLSLRKLML GHNHMQNLPT 600

LIEHIPLEVL DVQHNALTRL PDTLFSKALN LRYLNASANS LESLPSACTG EESLSMLQLL 660

YLTNNLLTDQ CIPVLVGHLH LRILHLANNQ LQTFPASKLN KLEQLEELNL SGNKLKTIPT 720

TIANCKRLHT LVAHSNNISI FPEILQLPQI QFVDLSCNDL TEILIPEALP ATLQDLDLTG 780

NTNLVLEHKT LDIFSHITTL KIDQKPLPTT DSTVMSTFWS HGLAEMAGQR NKLCVSALAM 840

DNFAEGVGAV YGMFDGDRNE ELPRLLQCTM ADVLLEEVQQ STNDTVFMAN TFLVSHRKLG 900

MAGQKLGSSA LLCYIRPDTA DPASSFSLTV ANVGTCQAVL CRGGKPVPLS KVFSLEQDPE 960

EAQRVKDQKA IITEDNKVNG VTCCTRMLGC TYLYPWILPK PHISSTPLTI QDELLILGNK 1020

ALWEHLSYTE AVNAVRHVQD PLAAAKKLCT LAQSYGCQDN VGAMVVYLNI GEEGCTCEMN 1080

GLTLPGPVGF ASTTTIKDAP KPATPSSSSG IASEFSSEMS TSEVSSEVGS TASDEHTTGG 1140

LDAALLPRPE RRCSLHPTPT SGLFQRQPSC ATFSSNQSDN GLDSDDDQPV EGVITNGSKV 1200

EVEVDIHCCR GRDLENSPPL IESSPTPCSE EHARGSCFGI RRQNSVNSGI LLPMSKDRME 1260

LQKSPSTSCL YGKKLSNGSI VPLEDSLNLI EVATEVPKRK TGYFAAPTQM EPEDQFVVPR 1320

DLEEEVKEQM KQHQDSRLEP EPHEEDRTEP LEEFDTAL 1358

Nucleotide Sequence
(FASTA)

ATGGGGGAGG TGGAGCCAGG GCCCGCGGGC CCGCTGGATC CCCCGGAGCC GCCCGAAGCG 60

CCCGCGAGCC GCCGGCCGGG AGGGATCCGG TTCCTGAAGA GAAATATGAA ACGCAATGGG 120

AGCAGAAATT GTTTGAATAG GAGAAGTAGG TTTGGTTCTC GAGAAAGAGA CTGGCTAAGA 180

GAAGATGTAA AGAGAGGCTG TGTTTACCTT TATGGAGCAG ACACTACCAC TGCCACTACA 240

ACCACCACCA CCTCCTCTTC CACTTCCTCC TCCTCCTCTT CCTCTGACTT ACATCTCGTC 300

CTTTGCACTG TAGAGACACC AGCATCAGAA ATATGTGCTG GAGAGGGAAG AGAAAGTCTT 360

TATTTGCAAC TTCATGGAGA CCTGGTCAGG AGACTGGAAC CTACTGAACG ACCTCTTCAG 420

ATCGTTTATG ATTACTTATC CAGGCTGGGA TTTGATGATC CTGTGCGCAT ACAGGAGGAG 480

GCTACAAATC CTGACCTCGG CTGTATGATT CGATTTTATG GTGAAAAACC GTGCCACATG 540

GATCATTTGG ATCGAATCCT ACTGTCTGGC ATCTATAATG TACGCAAGGG AAAGACCCAG 600

CTGCATAAGT GGGCTGAGCG CCTAGTTGTC CTCTGTGGTA CCTGCCTTAT TGTTTCCTCA 660

GTGAAGGATT GTCAAACTGG AAAGATGCAC ATTTTGCCTC TGGTTGGTGG AAAGATAGAA 720

GAAGTGAAGC GACGGCAGTA CTCCCTTGCT TTCAGCTCAG CAGGAGCCCA AGCTCAGACC 780

TATCATGTCA GCTTCGAGAC TTTGGCCGAG TACCAGCGAT GGCAACGGCA AGCATCCAAG 840

GTGGTGTCCC AGCGAATCAG TACTGTGGAT CTCTCATGTT ACAGCCTCGA GGAGGTTCCT 900

GAGCATCTCT TCTATAGTCA AGATATTACC TACCTCAACT TGCGACACAA CTTCATGCAG 960

TTAGAAAGAC CCGGAGGCCT CGATACACTC TACAAATTTT CTCAACTGAA GGGCCTGAAC 1020

TTGTCCCATA ATAAACTTGG GTTGTTTCCT ATATTGTTAT GCGAGATCTC TACCCTGACT 1080

GAGCTCAACG TTTCCTGTAA TGGATTTCGT GACCTACCAA GTCAAATTGG CAATCTGCTA 1140

AATCTTCAAA CCCTCTGTCT TGATGGCAAC TTTCTGACTA CTTTACCTGA AGAATTGGGA 1200

AATCTACAAC AGCTTTCCTC CTTGGGAATT TCCTTCAACA ACTTTAGTCA AATTCCTGAG 1260

GTTTATGAGA AACTCACTAT GTTAGATAGA GTGGTTATGG CAGGAAATTG CCTGGAAGTC 1320

CTGAACTTAG GGGTGCTGAA TAGGATGAAC CATATCAAGC ATGTGGATTT AAGGATGAAC 1380

CATTTGAAAA CCATGGTTAT TGAAAATCTG GAGGGAAATA AACACATCAC CCACGTGGAT 1440

CTGCGGGACA ACCGACTGAC TGACTTGGAT CTTAGCTCCT TATGCAGCTT GGAACAGCTG 1500

CACTGTGGGC GGAATCAGCT GAGGGAGCTA ACACTCAGTG GCTTCTCCCT TCGGACCCTC 1560

TATGCCAGTT CCAACAGGCT GACAGCAGTG AACATTTATC CAGTACCCAG CCTGCTTACT 1620

TCCTTGGATC TCTCCCGAAA CCTGCTAGAG TGTGTCCCTG ACTGGGCCTG TGAAGCAAAG 1680

AAGATAGAAG TATTAGATGT GAGCTATAAT CTTCTCACAG AGGTTCCCAT GAGAATTCTG 1740

AGTAGCTTGA GTCTTAGAAA ACTGATGCTG GGACACAATC ACATGCAAAA CCTCCCAACA 1800

CTGATAGAGC ACATCCCCCT TGAGGTGTTG GATGTTCAGC ATAATGCACT CACGAGGCTG 1860

CCAGACACTC TCTTCTCCAA GGCCTTAAAT CTCAGATACT TGAATGCATC TGCAAATAGT 1920

CTGGAGTCTT TACCATCCGC CTGCACTGGA GAGGAGAGTT TGAGTATGCT GCAGCTGCTT 1980

TATCTGACCA ACAATCTCCT GACGGATCAG TGCATACCTG TCCTGGTAGG GCACCTGCAC 2040

CTGCGAATCT TGCACCTTGC AAACAATCAG TTACAGACCT TTCCTGCAAG CAAACTAAAT 2100

AAATTGGAGC AATTGGAGGA ACTGAACCTA AGTGGCAACA AACTTAAAAC CATTCCCACA 2160

ACCATAGCAA ACTGCAAAAG GCTGCACACC CTTGTTGCAC ACTCCAACAA CATCAGCATT 2220

TTCCCAGAAA TACTGCAGTT GCCTCAGATC CAGTTTGTAG ACCTAAGTTG CAACGACTTG 2280

ACAGAAATCC TGATTCCAGA GGCTTTGCCT GCTACATTAC AAGACCTTGA CCTGACTGGA 2340

AATACAAATC TGGTTCTGGA ACACAAGACA CTGGACATAT TTAGCCATAT CACAACCCTG 2400

AAAATTGATC AGAAACCTTT GCCAACCACA GATTCTACAG TTATGTCAAC CTTCTGGAGC 2460

CATGGACTGG CTGAGATGGC AGGGCAGAGA AATAAGCTGT GTGTCTCAGC ACTTGCTATG 2520

GATAACTTTG CAGAGGGGGT GGGAGCTGTG TATGGCATGT TTGATGGAGA CCGAAATGAG 2580

GAGCTCCCGC GCCTGCTGCA GTGTACGATG GCAGATGTGC TTTTAGAAGA GGTACAGCAG 2640

TCAACTAATG ACACAGTTTT CATGGCTAAC ACCTTCTTGG TATCTCACAG GAAATTAGGA 2700

ATGGCTGGCC AGAAGTTGGG CTCCTCCGCT CTCCTGTGCT ACATCCGCCC TGACACTGCC 2760

GATCCAGCAA GTAGCTTTAG CTTGACTGTA GCCAATGTTG GCACGTGCCA AGCAGTCCTG 2820

TGCCGAGGTG GGAAGCCAGT GCCCCTCTCT AAAGTCTTCA GCCTGGAGCA GGACCCAGAG 2880

GAGGCGCAAA GGGTGAAGGA CCAAAAAGCC ATCATCACAG AGGACAACAA AGTGAATGGG 2940

GTAACCTGCT GTACCCGGAT GCTGGGCTGT ACATACCTCT ACCCTTGGAT CCTCCCCAAG 3000

CCCCACATAT CTTCCACTCC ACTGACCATT CAAGATGAGT TGCTGATTCT GGGAAACAAA 3060

GCATTGTGGG AACACTTGTC CTACACGGAA GCTGTCAATG CTGTACGTCA TGTACAAGAC 3120

CCATTAGCAG CTGCTAAGAA GCTGTGCACA TTAGCGCAGA GCTATGGCTG TCAGGACAAT 3180

GTAGGGGCGA TGGTGGTTTA TTTGAATATT GGTGAGGAAG GCTGCACTTG TGAAATGAAT 3240

GGGCTCACCC TCCCAGGTCC TGTGGGATTT GCTTCAACCA CCACTATCAA GGATGCCCCT 3300

AAGCCAGCCA CTCCATCCTC TAGCAGTGGG ATTGCCTCTG AGTTCAGTAG TGAGATGTCC 3360

ACCTCAGAGG TGAGCAGTGA AGTGGGGTCC ACTGCTTCTG ATGAGCATAC TACTGGGGGC 3420

CTGGACGCTG CCTTGCTTCC GAGGCCAGAG CGGCGCTGCA GCCTCCACCC AACACCCACC 3480

TCTGGGCTGT TTCAGCGCCA GCCTTCTTGT GCTACTTTCT CCAGTAACCA GTCTGACAAC 3540

GGCCTGGACA GTGATGATGA CCAGCCCGTT GAGGGGGTCA TAACCAATGG CAGCAAGGTA 3600

GAGGTGGAAG TAGACATCCA CTGCTGCAGG GGGAGGGATC TGGAGAACTC ACCCCCTCTC 3660

ATAGAGAGTT CTCCTACCCC GTGTTCTGAG GAACATGCTA GAGGGTCGTG TTTTGGGATC 3720

CGAAGACAGA ACAGTGTGAA TAGTGGCATA CTCCTGCCAA TGAGCAAGGA CAGGATGGAG 3780

TTACAGAAGT CTCCCTCCAC CTCCTGCCTC TATGGGAAGA AACTCTCCAA TGGCTCTATT 3840

GTGCCCCTAG AGGACAGCCT GAACCTCATT GAAGTGGCCA CAGAAGTGCC CAAGAGGAAA 3900

ACTGGCTATT TTGCTGCCCC CACTCAGATG GAACCAGAGG ACCAGTTTGT TGTGCCTCGT 3960

GACCTGGAAG AAGAAGTGAA GGAACAAATG AAACAGCACC AGGACAGCCG GCTCGAGCCT 4020

GAGCCCCACG AAGAGGATCG GACCGAGCCC CTGGAGGAGT TTGACACAGC ACTATGA 4077

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g++++ g+rn+++ ++ +++nf++  +     a++g++DG++++e  + +++++ ++l

Q: 820   SHGLAEMAGQRNKLCVSALAMDNFAEGVG-----AVYGMFDGDRNEELPRLLQCTMADVL  874

         6899*********************9877.....59************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

          ee++    ++++ + ++a++Fl  +++l       ++ +k Gs+a++++i+++

Q: 875   LEEVQ----QSTNDTVFMANTFLVSHRKL------GMAGQKLGSSALLCYIRPDtadpas  924

         ***99....77888889************......89***************99999***

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsre.dEleRieeaggsvilkdgaRvlGvL  172

           +l+vanvG ++avLcr+gk+v+ls+ ++ +++ +E +R++++++ +++++  +v+Gv+

Q: 925   sfSLTVANVGTCQAVLCRGGKPVPLSKVFSLEQDpEEAQRVKDQKAIITEDN--KVNGVT  982

         ******************************99866**********9999998..******

S: 173   avsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekk  232

         +++R+lG++yl+p++ p+P+++s++lt +de liL+ + lw+++s  eav++vr+v +

Q: 983   CCTRMLGCTYLYPWILPKPHISSTPLTIQDELLILGNKALWEHLSYTEAVNAVRHVQD--  1040

         **********************************************************..

S: 233   eaeqeaakkLvklalargskdnvsaivv  260

           + +aakkL++la+++g++dnv a+vv

Q: 1041  --PLAAAKKLCTLAQSYGCQDNVGAMVV  1066

         ..************************97

Domain Sequence
(FASTA)

SHGLAEMAGQ RNKLCVSALA MDNFAEGVGA VYGMFDGDRN EELPRLLQCT MADVLLEEVQ 60

QSTNDTVFMA NTFLVSHRKL GMAGQKLGSS ALLCYIRPDT ADPASSFSLT VANVGTCQAV 120

LCRGGKPVPL SKVFSLEQDP EEAQRVKDQK AIITEDNKVN GVTCCTRMLG CTYLYPWILP 180

KPHISSTPLT IQDELLILGN KALWEHLSYT EAVNAVRHVQ DPLAAAKKLC TLAQSYGCQD 240

NVGAMVV 247

Keyword

Complete proteome; Leucine-rich repeat; Reference proteome; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>