| Tag | Content |
|---|
| EKPD ID | EPS-POA-00013 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| DSP/aDSP | 157.6 | 1.9E-46 | 31 | 177 | 147 |
|
| Status | Reviewed |
| Ensembl Protein | ENSPPYP00000009390 |
| UniProt Accession | Q5RD73; |
| Protein Name | Dual specificity protein phosphatase 3 |
| Protein Synonyms/Alias | Vaccinia H1-related phosphatase; VHR; |
| Gene Name | DUSP3 |
| Gene Synonyms/Alias | DUSP3; |
| Ensembl Information | |
| Organism | Pongo abelii |
| Functional Description | Shows activity both for tyrosine-protein phosphate andserine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2 (By similarity). |
| Protein Length | 185 |
Protein Sequence
(FASTA) | | MSGSFELSVQ DLNDLLSDGS GCYSLPSQPC NEVTPRIYVG NASVAQDIPK LQKLGITHVL 60 | | NAAEGRSFMH VNTNANFYKD SGITYLGIKA NDTQEFNLSA YFERAADFID QALAQKNGRV 120 | | LVHCREGYSR SPTLVIAYLM MRQKMDVKSA LSIVRQNREI GPNDGFLAQL CQLNDRLAKE 180 | | GKLKP 185 |
|
Nucleotide Sequence
(FASTA) | | ATGTCGGGCT CGTTCGAGCT CTCGGTGCAG GATCTCAACG ACCTGCTCTC GGACGGCAGC 60 | | GGCTGCTACA GCCTCCCGAG CCAGCCCTGC AACGAGGTCA CCCCGCGGAT CTACGTGGGC 120 | | AACGCGTCTG TGGCTCAGGA TATCCCCAAG CTGCAGAAAC TAGGCATCAC CCATGTGCTG 180 | | AACGCGGCTG AGGGCAGGTC CTTCATGCAC GTCAACACCA ATGCCAACTT CTACAAGGAC 240 | | TCCGGCATCA CATACCTGGG CATCAAGGCC AACGACACAC AGGAGTTCAA CCTCAGCGCT 300 | | TACTTTGAAA GGGCTGCCGA CTTCATTGAC CAGGCTTTGG CTCAAAAGAA TGGCCGGGTG 360 | | CTCGTCCACT GCCGGGAAGG TTACAGCCGC TCCCCAACGC TAGTTATCGC CTACCTCATG 420 | | ATGCGGCAGA AGATGGACGT CAAGTCTGCC CTGAGCATCG TGAGGCAGAA CCGTGAGATC 480 | | GGCCCCAACG ATGGCTTCCT GGCCCAGCTC TGCCAACTCA ATGACAGACT AGCCAAGGAG 540 | | GGGAAGTTGA AACCCTAG 558 |
|
| Domain Profile | S: 3 teilpglylgdqataldrreLsklgitvvinaslsv..ikvqviPeylikkgityknipv 60 | +e++p++y+g++ +a d +L+klgit+v+na+ ++ ++v++ +++ ++gity++i++ | Q: 31 NEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRsfMHVNTNANFYKDSGITYLGIKA 90 | 79******************************9754227889999*************** |
| S: 61 dDsdvtdllqyfdeaaefidea.kekggkvlvHCaaGvsRSatlvlaYLmkveglslsdA 119 | +D+++++l+ yf++aa+fid+a +k+g+vlvHC+ G+sRS+tlv+aYLm+++++ +++A | Q: 91 NDTQEFNLSAYFERAADFIDQAlAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSA 150 | **********************9999********************************** |
| S: 120 ieavkrkrpsiepnegfleQLlelekkl 147 | ++ v+++r +i pn+gfl+QL++l+ +l | Q: 151 LSIVRQNR-EIGPNDGFLAQLCQLNDRL 177 | ********.***************9876 |
|
Domain Sequence
(FASTA) | | NEVTPRIYVG NASVAQDIPK LQKLGITHVL NAAEGRSFMH VNTNANFYKD SGITYLGIKA 60 | | NDTQEFNLSA YFERAADFID QALAQKNGRV LVHCREGYSR SPTLVIAYLM MRQKMDVKSA 120 | | LSIVRQNREI GPNDGFLAQL CQLNDRL 147 |
|
| Keyword | Complete proteome; Hydrolase; Nucleus; Protein phosphatase; Reference proteome. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | |
| KEGG | |
| InterPros | |
| Pfam | |
| SMARTs | |
| Prosites | |
| Prints | |
| Created Date | 20-Feb-2013 |