EKS-POA-00406

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-POA-00406

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/DAPK	462.3	4.4E-139	13	275	263

Status

Unreviewed

Ensembl Protein

ENSPPYP00000010533

UniProt Accession

H2NX15;

Protein Name

Protein Synonyms/Alias

Gene Name

DAPK3

Gene Synonyms/Alias

DAPK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPPYG00000009392	ENSPPYP00000010533	ENSPPYT00000010947

Organism

Pongo abelii

Functional Description

Protein Length

454

Protein Sequence
(FASTA)

MSTFRQEDVE DHYEMGEELG SGQFAIVRKC RQKGTGKEYA AKFIKKRRLS SSRRGVSREE 60

IEREVNILRE IRHPNIITLH DIFENKTDVV LILELVSGGE LFDFLAEKES LTEDEATQFL 120

KQILDGVHYL HSKRIAHFDL KPDIFLSFHK NVPNPGLKLI DFGIAHNIEA GNEFKNIFGT 180

PEFVAPEIVN YEPLGLEADM WSIGVITYIL LSGASPFLGE TKQETLTNIS AVNYDFDEEY 240

FSNTSELAKD FIRRLLVKDP KRRMTIAQSL EHSWIKAIRR RNVRGEDSGR KPERRRLKTT 300

RLKEYTIKSH SSLPPNNSYA DFERFSKVLE EAAAAEEGLR ELQRSRRLCH EDVEALAAIY 360

EEKEAWYREE SDSLGQDLRR LRQELLKTEA LKRQAQEEAK GALLGTSGLK RRFSRLENRY 420

EALAKQVASE MRFVQDLVRA LEQEKLQGVE CGLR 454

Nucleotide Sequence
(FASTA)

ATGTCCACAT TCAGGCAGGA AGACGTGGAG GACCATTATG AGATGGGGGA GGAGCTGGGC 60

AGCGGCCAGT TTGCGATCGT GCGGAAGTGT CGGCAGAAGG GCACAGGCAA GGAGTACGCG 120

GCCAAGTTCA TCAAGAAGCG CCGCCTGTCA TCCAGCCGGC GTGGGGTGAG CCGGGAGGAG 180

ATTGAGCGGG AGGTGAACAT CCTGCGGGAG ATCCGGCACC CCAACATCAT CACCCTGCAC 240

GACATCTTCG AGAATAAGAC GGACGTGGTC CTCATCCTGG AGCTGGTCTC CGGTGGGGAG 300

CTCTTTGACT TCCTGGCGGA GAAGGAGTCA CTGACGGAGG ACGAGGCCAC CCAGTTCCTC 360

AAGCAGATCC TGGACGGCGT TCACTACTTG CACTCCAAGC GCATCGCACA CTTTGACCTG 420

AAGCCTGATA TCTTCCTGTC GTTCCACAAG AACGTGCCGA ACCCAGGCCT CAAGCTCATC 480

GACTTCGGCA TCGCGCACAA CATCGAGGCG GGGAATGAGT TCAAGAACAT CTTCGGCACC 540

CCGGAGTTTG TGGCCCCAGA GATTGTGAAC TATGAGCCGC TGGGCCTGGA GGCGGACATG 600

TGGAGCATCG GCGTCATCAC CTACATCCTC CTGAGCGGCG CATCCCCGTT CCTGGGCGAG 660

ACCAAGCAGG AGACGCTTAC CAACATCTCA GCCGTGAACT ACGACTTCGA CGAGGAGTAC 720

TTCAGCAACA CCAGCGAGCT GGCCAAGGAC TTCATTCGCC GGCTGCTCGT CAAAGATCCC 780

AAGCGGAGAA TGACCATTGC CCAGAGCCTG GAACATTCCT GGATTAAGGC GATCCGGCGG 840

CGGAACGTTC GTGGTGAGGA CAGTGGCCGC AAGCCCGAGC GGCGGCGCCT GAAGACCACG 900

CGTCTGAAGG AGTACACCAT CAAGTCGCAC TCCAGCTTGC CGCCCAACAA CAGCTACGCC 960

GACTTCGAGC GCTTCTCCAA GGTGCTGGAG GAGGCGGCGG CCGCCGAGGA GGGCCTGCGC 1020

GAGCTGCAGC GTAGCCGGCG GCTCTGCCAC GAGGACGTGG AGGCGCTGGC CGCCATCTAC 1080

GAGGAGAAGG AGGCCTGGTA CCGCGAGGAG AGCGACAGCC TGGGCCAGGA CCTGCGGAGG 1140

CTACGGCAGG AGCTGCTCAA GACCGAGGCA CTCAAGCGGC AGGCGCAGGA GGAGGCCAAG 1200

GGCGCGCTGC TGGGCACCAG CGGCCTCAAG CGCCGCTTCA GCCGCCTGGA GAACCGCTAC 1260

GAGGCGCTGG CCAAGCAAGT GGCCTCCGAG ATGCGCTTCG TGCAGGACCT CGTGCGCGCC 1320

CTGGAGCAGG AGAAGCTGCA GGGTGTGGAG TGCGGGCTGC GCTAG 1365

Domain Profile

S: 1     letgkelgsGkfavvrkcrekstGkeyaakflkkrrlkssrrgvsreeierevavlkeir  60

         +e+g+elgsG+fa+vrkcr+k tGkeyaakf+kkrrl+ssrrgvsreeierev++l+eir

Q: 13    YEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREIR  72

         5789********************************************************

S: 61    sepnvinlhevyenksdvililelvaGGelfdllaekeslseeeatellkqilegvkylh  120

          +pn+i+lh+++enk+dv+lilelv+GGelfd+laekesl+e+eat++lkqil+gv+ylh

Q: 73    -HPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLH  131

         .***********************************************************

S: 121   skkivhldlkPenillldkkvpkgdiklidfGlsrkieegaelkeilGtPefvaPeivny  180

         sk+i+h+dlkP+  l  +k+vp++ +klidfG++++ie+g+e+k+i+GtPefvaPeivny

Q: 132   SKRIAHFDLKPDIFLSFHKNVPNPGLKLIDFGIAHNIEAGNEFKNIFGTPEFVAPEIVNY  191

         ************9999********************************************

S: 181   eplsletdmwsiGvityillsgasPflGdtkqetllnisavnldfseelfssvselakdf  240

         epl+le+dmwsiGvityillsgasPflG+tkqetl+nisavn+df+ee+fs++selakdf

Q: 192   EPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSNTSELAKDF  251

         ************************************************************

S: 241   irrllvkdpekrltieeclehswl  264

         irrllvkdp++r+ti+++lehsw+

Q: 252   IRRLLVKDPKRRMTIAQSLEHSWI  275

         ***********************8

Domain Sequence
(FASTA)

YEMGEELGSG QFAIVRKCRQ KGTGKEYAAK FIKKRRLSSS RRGVSREEIE REVNILREIR 60

HPNIITLHDI FENKTDVVLI LELVSGGELF DFLAEKESLT EDEATQFLKQ ILDGVHYLHS 120

KRIAHFDLKP DIFLSFHKNV PNPGLKLIDF GIAHNIEAGN EFKNIFGTPE FVAPEIVNYE 180

PLGLEADMWS IGVITYILLS GASPFLGETK QETLTNISAV NYDFDEEYFS NTSELAKDFI 240

RRLLVKDPKR RMTIAQSLEH SWI 263

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sorex araneus"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006917	; P:induction of apoptosis
GO:0007243	; P:intracellular protein kinase cascade
GO:0090263	; P:positive regulation of canonical Wnt receptor signaling pathway

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR020675	; Myosin_light_ch_kinase-rel.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013