EPS-POA-00087

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-POA-00087

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Asp-Based PTP/FCP	85.4	4.5E-24	167	293	127

Status

Unreviewed

Ensembl Protein

ENSPPYP00000011162

UniProt Accession

H2NYS9;

Protein Name

Protein Synonyms/Alias

Mitochondrial import inner membrane translocase subunit TIM50;

Gene Name

TIMM50

Gene Synonyms/Alias

TIMM50;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPPYG00000009969	ENSPPYP00000011161	ENSPPYT00000011596
ENSPPYG00000009969	ENSPPYP00000011162	ENSPPYT00000011597

Organism

Pongo abelii

Functional Description

Protein Length

351

Protein Sequence
(FASTA)

MAASAAVFSR LRSGLRLGSR GLCTRLATPP PRAPDQAAEI GSRGSTKAQG PQQQPGSEGP 60

SYAKKVALWL AGLLGAGGTV SVVYIFGNNP VDENGAKVRG ERDRGLARDP ILVQQLRRTY 120

KYFKDYRQMI IEPTSPCLLP DPLQEYYQPP YTLVLGAHRR PWVCGPGWRF KKRPGIESVF 180

QQLAPLYEMS LTSETGMTAF PLIDSVDPHG FISYRLFRDA TRYMDGHHVK DISCLNRDPA 240

RVVVVDCKKE AFRLQPYNGV ALRPWDGNSD DRVLLDLSAF LKTIALNGVE DVRTVLEHYA 300

LEDDPLAAFK QRQSRLEQEE QQRLAELSKS NKQNLFLGSL TSRLWPRSKQ P 351

Nucleotide Sequence
(FASTA)

ATGGCGGCTT CGGCAGCGGT GTTCTCACGC TTGCGGAGCG GGCTCCGGCT CGGCTCGCGG 60

GGACTGTGTA CGAGGTTGGC GACGCCGCCC CCCCGGGCCC CAGATCAGGC CGCAGAGATC 120

GGGAGCCGCG GGAGCACTAA GGCACAAGGG CCACAGCAGC AGCCGGGCTC AGAGGGTCCC 180

AGCTATGCCA AAAAAGTTGC GCTCTGGCTT GCTGGGCTGC TTGGAGCTGG TGGGACTGTG 240

AGCGTCGTCT ATATCTTTGG AAACAACCCG GTGGACGAAA ATGGTGCCAA GGTGAGGGGG 300

GAAAGAGATC GAGGCCTTGC CAGGGATCCA ATTCTGGTAC AGCAGTTGCG CCGGACATAC 360

AAATATTTCA AAGATTATAG ACAGATGATC ATCGAGCCCA CCAGCCCTTG CCTTCTCCCA 420

GACCCTCTGC AGGAATACTA CCAGCCACCC TACACGCTCG TTTTGGGAGC TCACCGGCGG 480

CCTTGGGTAT GTGGCCCTGG CTGGAGGTTT AAGAAGCGCC CAGGCATCGA GTCCGTGTTC 540

CAGCAGCTTG CCCCTTTATA TGAAATGTCA CTTACGTCAG AGACTGGCAT GACTGCGTTT 600

CCACTCATTG ATAGTGTGGA CCCCCACGGC TTCATCTCCT ACCGCCTATT CCGGGACGCC 660

ACGAGATACA TGGATGGACA CCATGTTAAG GATATTTCAT GTCTGAATCG GGACCCAGCT 720

CGAGTAGTAG TTGTGGACTG CAAGAAGGAA GCCTTCCGCC TGCAGCCGTA TAACGGTGTC 780

GCCCTGCGGC CCTGGGACGG CAACTCTGAT GACCGGGTCT TGTTGGATCT GTCTGCCTTC 840

CTCAAGACCA TTGCACTGAA TGGTGTGGAG GACGTGCGAA CCGTGCTGGA GCACTACGCC 900

CTGGAGGATG ACCCGCTGGC GGCTTTCAAA CAGCGGCAAA GCCGGCTAGA GCAGGAGGAG 960

CAGCAGCGCC TGGCCGAGCT CTCCAAGTCC AACAAGCAGA ACCTCTTCCT CGGCTCCCTC 1020

ACCAGCCGCC TGTGGCCTCG CTCCAAACAG CCCTGA 1056

Domain Profile

S: 26    kasvkkRPgldeFLkelskayevviftasskeyadavldkldpkkklfkkrlyresctle  85

          +++kkRPg +  +++l+  ye+ + t+++ ++a +++d +dp + ++++rl+r+ +++

Q: 167   GWRFKKRPGIESVFQQLAPLYEMSL-TSETGMTAFPLIDSVDP-HGFISYRLFRDATRYM  224

         689*******************987.67777************.6799************

S: 86    ngkyvKdLsllgrdlskvvivDdsprsfelqpdnlipiepfygdsdkdtellkllpflea  145

         +g++vKd+s l+rd  +vv+vD ++++f+lqp+n++ ++p+ g+ ++d+ ll+l+ fl+

Q: 225   DGHHVKDISCLNRDPARVVVVDCKKEAFRLQPYNGVALRPWDGN-SDDRVLLDLSAFLKT  283

         **99***************************************9.999**********99

S: 146   le..ksddvr  153

         ++   ++dvr

Q: 284   IAlnGVEDVR  293

9984559997

Domain Sequence
(FASTA)

GWRFKKRPGI ESVFQQLAPL YEMSLTSETG MTAFPLIDSV DPHGFISYRL FRDATRYMDG 60

HHVKDISCLN RDPARVVVVD CKKEAFRLQP YNGVALRPWD GNSDDRVLLD LSAFLKTIAL 120

NGVEDVR 127

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005744	; C:mitochondrial inner membrane presequence translocase complex
GO:0016607	; C:nuclear speck
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0004725	; F:protein tyrosine phosphatase activity
GO:0043021	; F:ribonucleoprotein complex binding
GO:0007006	; P:mitochondrial membrane organization
GO:0001836	; P:release of cytochrome c from mitochondria

KEGG

InterPros

IPR023214	; HAD-like_dom.
IPR004274	; NIF.

Pfam

PF03031

; NIF; 1.

SMARTs

SM00577

; CPDc; 1.

Prosites

PS50969

; FCP1; 1.

Prints

Created Date

20-Feb-2013