EKS-POA-00418

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-POA-00418

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/SGK	530.1	1.2E-159	35	292	258

Status

Unreviewed

Ensembl Protein

ENSPPYP00000012308

UniProt Accession

H2P1Z0;

Protein Name

Protein Synonyms/Alias

Serine/threonine-protein kinase Sgk3;

Gene Name

SGK3

Gene Synonyms/Alias

SGK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPPYG00000011020	ENSPPYP00000012308	ENSPPYT00000012789

Organism

Pongo abelii

Functional Description

Protein Length

367

Protein Sequence
(FASTA)

MNSSPAGTPS PQPSRANGNI NLGPSANPNA RPTDFDFLKV IGKGNYGKVL LAKRKSDGTF 60

YAVKVLQKKS ILKKKEQSHI MAERSVLLKN VRHPFLVGLR YSFQTPEKLY FVLDYVNGGE 120

LFFHLQRERR FLEPRARFYA AEVASAIGYL HSLNIIYRDL KPENILLDCQ GHVVLTDFGL 180

CKEGVEPEET TSTFCGTPEY LAPEVLRKEP YDRAVDWWCL GAVLYEMLHG LPPFYSQDVS 240

QMYENILHQP LQIPGGRTVA ACDLLQSLLH KDQRQRLGSK ADFLEIKNHV FFSPINWDDL 300

YHKRLTPPFN PNVAGPADLK HFDPEFTQEA VSKSIGCTPD TVASSSGASS AFLGFSYAPE 360

DDDILDC 367

Nucleotide Sequence
(FASTA)

ATGAACTCTA GCCCAGCTGG GACCCCCAGT CCACAGCCCT CCAGGGCCAA TGGGAACATC 60

AACCTGGGGC CTTCAGCCAA CCCAAATGCC CGGCCCACGG ACTTCGACTT CCTCAAAGTC 120

ATCGGCAAAG GGAACTACGG GAAGGTCCTA CTGGCCAAGC GCAAGTCTGA TGGGACGTTC 180

TATGCAGTGA AGGTGCTGCA GAAAAAGTCC ATCTTAAAGA AGAAAGAGCA GAGCCACATC 240

ATGGCAGAAC GCAGTGTGCT TCTGAAGAAT GTGCGGCACC CCTTCCTCGT GGGCCTGCGC 300

TACTCCTTCC AGACACCTGA GAAGCTCTAC TTCGTGCTCG ACTATGTCAA CGGGGGAGAG 360

CTCTTCTTCC ACCTGCAGCG GGAGCGCCGG TTCCTGGAGC CCCGGGCCAG GTTCTACGCT 420

GCTGAGGTGG CCAGCGCCAT TGGCTACCTG CACTCCCTCA ACATCATTTA CAGGGACCTG 480

AAGCCAGAGA ACATTCTCTT GGACTGCCAG GGACACGTGG TGCTGACGGA TTTTGGCCTC 540

TGCAAGGAAG GTGTAGAGCC TGAAGAGACC ACATCCACGT TCTGTGGTAC CCCTGAGTAC 600

TTGGCACCTG AAGTGCTTCG GAAAGAGCCT TATGATCGAG CAGTGGACTG GTGGTGCTTG 660

GGGGCAGTCC TCTACGAGAT GCTCCATGGC CTGCCGCCCT TCTACAGCCA AGACGTATCC 720

CAGATGTATG AGAACATTCT GCACCAGCCG CTACAGATCC CCGGGGGCCG GACGGTGGCC 780

GCCTGTGACC TCCTGCAAAG CCTTCTCCAC AAGGACCAGA GGCAGCGTCT GGGCTCCAAA 840

GCAGACTTTC TTGAGATTAA GAACCATGTA TTCTTCAGCC CCATAAACTG GGATGACCTG 900

TACCACAAGA GGCTAACTCC ACCCTTCAAC CCAAATGTGG CAGGACCTGC TGACTTGAAG 960

CATTTTGACC CAGAGTTCAC CCAGGAAGCT GTGTCCAAGT CCATTGGCTG TACCCCTGAC 1020

ACTGTGGCCA GCAGCTCTGG GGCCTCAAGT GCATTCCTGG GATTTTCTTA TGCGCCAGAG 1080

GATGATGACA TCTTGGATTG CTAG 1104

Domain Profile

S: 1     fdflkvigkgsfgkvllakrkadekfyavkvlqkkailkkkeekhimaernvllknvkhp  60

         fdflkvigkg++gkvllakrk+d++fyavkvlqkk+ilkkke++himaer+vllknv+hp

Q: 35    FDFLKVIGKGNYGKVLLAKRKSDGTFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHP  94

         9***********************************************************

S: 61    flvglhysfqtaeklyfvldyvnggelffhlqrersfleprarfyaaeiasalgylhsln  120

         flvgl+ysfqt+eklyfvldyvnggelffhlqrer+fleprarfyaae+asa+gylhsln

Q: 95    FLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSLN  154

         ************************************************************

S: 121   ivyrdlkpenilldskghvvltdfglckeeieaedttstfcgtpeylapevlrkkpydrt  180

         i+yrdlkpenilld++ghvvltdfglcke++e e+ttstfcgtpeylapevlrk+pydr+

Q: 155   IIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEETTSTFCGTPEYLAPEVLRKEPYDRA  214

         ************************************************************

S: 181   vdwwclgavlyemlyglppfysrdvaemydnilnkplqlkpgisvaalelleellekdrk  240

         vdwwclgavlyeml+glppfys+dv++my+nil++plq+++g++vaa++ll++ll+kd++

Q: 215   VDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQR  274

         ************************************************************

S: 241   krlgakedfleiknhvff  258

         +rlg+k+dfleiknhvff

Q: 275   QRLGSKADFLEIKNHVFF  292

         *****************9

Domain Sequence
(FASTA)

FDFLKVIGKG NYGKVLLAKR KSDGTFYAVK VLQKKSILKK KEQSHIMAER SVLLKNVRHP 60

FLVGLRYSFQ TPEKLYFVLD YVNGGELFFH LQRERRFLEP RARFYAAEVA SAIGYLHSLN 120

IIYRDLKPEN ILLDCQGHVV LTDFGLCKEG VEPEETTSTF CGTPEYLAPE VLRKEPYDRA 180

VDWWCLGAVL YEMLHGLPPF YSQDVSQMYE NILHQPLQIP GGRTVAACDL LQSLLHKDQR 240

QRLGSKADFL EIKNHVFF 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0015459	; F:potassium channel regulator activity
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013