EKS-POA-00441

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-POA-00441

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CK1/CK1	490.2	1.3E-147	9	269	261

Status

Unreviewed

Ensembl Protein

ENSPPYP00000013183

UniProt Accession

H2P4D3;

Protein Name

Protein Synonyms/Alias

Gene Name

CSNK1E

Gene Synonyms/Alias

CSNK1E;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPPYG00000011818	ENSPPYP00000013183	ENSPPYT00000013720

Organism

Pongo abelii

Functional Description

Protein Length

416

Protein Sequence
(FASTA)

MELRVGNKYR LGRKIGSGSF GDIYLGANIA SGEEVAIKLE CVKTKHPQLH IESKFYKMMQ 60

GGVGIPSIKW CGAEGDYNVM VMELLGPSLE DLFNFCSRKF SLKTVLLLAD QMISRIEYIH 120

SKNFIHRDVK PDNFLMGLGK KGNLVYIIDF GLAKKYRDAR THQHIPYREN KNLTGTARYA 180

SINTHLGIEQ SRRDDLESLG YVLMYFNLGS LPWQGLKAAT KRQKYERISE KKMSTPIEVL 240

CKGYPSEFST YLNFCRSLRF DDKPDYSYLR QLFRNLFHRQ GFSYDYVFDW NMLKFGAARN 300

PEDVDRERRE HEREERMGQL RGSATRALPP GPPTGATANR LRSAAEPVAS TPASRIQPAG 360

NTSPRAISRV DRERKVSMRL HRGAPANVSS SDLTGRQEVS RIPASQTSVP FDHLGK 416

Nucleotide Sequence
(FASTA)

ATGGAGCTAC GTGTGGGGAA CAAGTACCGC CTGGGACGGA AGATTGGGAG CGGGTCCTTC 60

GGAGATATCT ACCTGGGTGC CAACATCGCC TCTGGTGAGG AAGTCGCCAT CAAGCTGGAG 120

TGTGTGAAGA CAAAGCACCC CCAGCTGCAC ATCGAGAGCA AGTTCTACAA GATGATGCAG 180

GGCGGCGTGG GGATCCCGTC CATCAAGTGG TGCGGAGCTG AGGGCGACTA CAACGTGATG 240

GTCATGGAGC TGCTGGGGCC CAGCCTAGAG GACCTGTTCA ACTTCTGTTC CCGCAAGTTC 300

AGCCTCAAGA CGGTGCTGCT CCTGGCCGAC CAGATGATCA GCCGCATCGA GTATATCCAC 360

TCCAAGAACT TCATCCACCG GGATGTCAAG CCCGACAACT TCCTCATGGG GCTGGGGAAG 420

AAGGGCAACC TGGTCTACAT CATCGACTTC GGCCTGGCCA AGAAGTATCG GGACGCCCGC 480

ACCCACCAGC ACATTCCCTA CCGGGAAAAC AAGAACCTGA CCGGCACGGC CCGCTACGCT 540

TCCATCAACA CGCACCTGGG CATTGAGCAA AGCCGTCGAG ATGACCTGGA GAGCCTGGGC 600

TACGTGCTCA TGTACTTCAA CCTGGGCTCC CTGCCCTGGC AGGGGCTCAA AGCAGCCACC 660

AAGCGCCAGA AGTATGAGCG GATCAGCGAG AAGAAGATGT CAACGCCCAT CGAGGTCCTC 720

TGCAAAGGCT ATCCCTCCGA ATTCTCAACA TACCTCAACT TCTGCCGCTC CCTGCGGTTT 780

GACGACAAGC CCGACTACTC TTACCTACGT CAGCTCTTCC GCAACCTCTT CCACCGGCAG 840

GGCTTCTCCT ATGACTACGT CTTCGACTGG AACATGCTGA AATTCGGTGC AGCCCGGAAC 900

CCCGAGGACG TGGACCGGGA GCGGCGAGAA CACGAGCGCG AGGAGAGGAT GGGGCAGCTA 960

CGGGGGTCCG CGACCCGAGC CCTGCCCCCT GGCCCACCCA CGGGGGCCAC TGCCAACCGG 1020

CTCCGCAGTG CCGCCGAGCC CGTGGCTTCC ACGCCAGCCT CCCGCATCCA GCCGGCTGGC 1080

AATACTTCTC CCAGAGCGAT CTCACGGGTC GACCGGGAGA GGAAGGTGAG TATGAGGCTG 1140

CACAGGGGCG CGCCCGCCAA CGTCTCCTCC TCAGACCTCA CTGGGCGGCA AGAGGTCTCC 1200

CGGATCCCAG CCTCACAGAC AAGTGTGCCA TTTGACCATC TCGGGAAGTG A 1251

Domain Profile

S: 1     yrvvkkiGsGsfGdiylgknlasgeevaikleskkskapqlklesrvykilqggvgiPev  60

         yr+++kiGsGsfGdiylg+n+asgeevaikle++k+k+pql++es++yk++qggvgiP++

Q: 9     YRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGGVGIPSI  68

         89**********************************************************

S: 61    ryfgkekkynvlvldllGpsledlfdlcerkfslktvllladqlisrieyvhskeliyrd  120

         +++g+e++ynv+v++llGpsledlf++c+rkfslktvllladq+isriey+hsk++i+rd

Q: 69    KWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRD  128

         ************************************************************

S: 121   ikPdnfllgigrkgkkvylidfGlakkyrdaktkkhipyreeksltGtaryasinthlgk  180

         +kPdnfl+g+g+kg+ vy+idfGlakkyrda+t++hipyre+k+ltGtaryasinthlg+

Q: 129   VKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGI  188

         ************************************************************

S: 181   eqsrrddleslgyvllyflrgslPWqglkaatkkqkyekisekklstsievlcegfPeef  240

         eqsrrddleslgyvl+yf+ gslPWqglkaatk+qkye+isekk+st+ievlc+g+P+ef

Q: 189   EQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEF  248

         ************************************************************

S: 241   atylkyvrklkfeekPdyeyl  261

         +tyl+++r+l+f++kPdy+yl

Q: 249   STYLNFCRSLRFDDKPDYSYL  269

         *******************97

Domain Sequence
(FASTA)

YRLGRKIGSG SFGDIYLGAN IASGEEVAIK LECVKTKHPQ LHIESKFYKM MQGGVGIPSI 60

KWCGAEGDYN VMVMELLGPS LEDLFNFCSR KFSLKTVLLL ADQMISRIEY IHSKNFIHRD 120

VKPDNFLMGL GKKGNLVYII DFGLAKKYRD ARTHQHIPYR ENKNLTGTAR YASINTHLGI 180

EQSRRDDLES LGYVLMYFNL GSLPWQGLKA ATKRQKYERI SEKKMSTPIE VLCKGYPSEF 240

STYLNFCRSL RFDDKPDYSY L 261

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0030529	; C:ribonucleoprotein complex
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0034613	; P:cellular protein localization
GO:0030178	; P:negative regulation of Wnt receptor signaling pathway
GO:0090263	; P:positive regulation of canonical Wnt receptor signaling pathway
GO:0032436	; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013