EKS-POA-00110

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-POA-00110

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NAK	393.8	4.0E-118	46	309	264

Status

Unreviewed

Ensembl Protein

ENSPPYP00000013757

UniProt Accession

H2P5Y7;

Protein Name

Protein Synonyms/Alias

Gene Name

AAK1

Gene Synonyms/Alias

AAK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPPYG00000012336	ENSPPYP00000013757	ENSPPYT00000014316

Organism

Pongo abelii

Functional Description

Protein Length

1306

Protein Sequence
(FASTA)

MKKFFDSRRE QGGSGLGSGS SGGGGSTSGL GSGYIGRVFG IGRQQVTVDE VLAEGGFAIV 60

FLVRTSNGMK CALKRMFVNN EHDLQVCKRE IQIMRDLSGH KNIVGYIDSS INNVSSGDVW 120

EVLILMDFCR GGQVVNLMNQ RLQTGFTENE VLQIFCDTCE AVARLHQCKT PIIHRDLKVE 180

NILLHDRGHY VLCDFGSATN KFQNPQTEGV NAVEDEIKKY TTLSYRAPEM VNLYSGKIIT 240

TKADIWALGC LLYKLCYFTL PFGESQVAIC DGNFTIPDNS RYSQDMHCLI RYMLEPDPDK 300

RPDIYQVSYF SFKLLKKECP IPNVQNSPIP AKLPEPVKAS EAAAKKTQPK ARLTDPIPTT 360

ETSIAPRQRP KAGQTQPNPG ILPIQPALTP RKRATVQPPP QAAGSSNQPG LLASVPQPKP 420

QAPPSQPLPQ TQAKQPQAPP TPQQTPSTQA QGLPAQAQAT PQHQQQLFLK QQQQQQQPPP 480

PQQQPAGTFY QQQQQAQTQQ FQAVHPATQQ PAIAQFPVVS QGGSQQQLMQ NFYQQQQQQQ 540

QQQQQQQLAT ALHQQQLMTQ QAALQQKPTV AAGQQPQPQP AAAPQPAPAQ EPAIQAPVRQ 600

QPKVQTTPPP AVQGQKVGSL TPPSSPKTQR AGHRRILSDV THSAVFGVPA SKSTQLLQAA 660

AAEASLNKSK SATTTPSGSP RTSQQNVYNP SEGSTWNPFD DDNFSKLTAE ELLNKDFAKL 720

GEGKHPEKLG GSAESLIPGF QSTQGDAFAT TSFSAGTAEK RKGGQTVDSG LPLLSVSDPF 780

IPLQVPDAPE KLIEGLKSPD TSLLLPDLLP MTDPFGSTSD AVIEKADVAV ESLIPGLEPP 840

VPQRLPSQTE SVTSNRTDSL TGEDSLLDCS LLSNPTTDLL EEFAPTAISA PVHKAAEDSN 900

LISGFDVPEG SDKVAEDEFD PIPVLITKNP QGLQRESNPC PVITVEHFKE SLGVKGLPLY 960

PDPSRVPGTK TQNNLESDYL ARDGPSSNSS FHSSEEEGTD LEGDMLDCSG SRPLLMESEE 1020

EDESCRPPQG KLGGVVPFVP PEVSPEQAKT VQGGRKNQFQ ALTQPATDGL SEPDVFAIAP 1080

FRSSRVPNDD MDIFSKAPFV SKSSMAPSQP EESDVFLRAP FTKKKSMEEL TVIQSTSQEL 1140

PAQTGLLSQT GDVPLPVGRE RAVYTSVQAQ YSTAGFVQQS NLLSHSVQAA DHLDSISPRG 1200

SCLESGGHSN DRNKGPQLQK EAVSGPMAGK PFRPQSLSKY SRHYSPEDEP SPEAQPIAAY 1260

KIVSQTNKQS IAGSVSITSL SSRTTELPAA DPFALAPFPS KSGKKP 1306

Nucleotide Sequence
(FASTA)

ATGAAGAAGT TTTTCGACTC CCGGCGAGAG CAGGGCGGCT CTGGCCTGGG CTCCGGCTCC 60

AGCGGAGGAG GGGGCAGCAC CTCGGGCCTG GGCAGTGGCT ACATCGGAAG AGTCTTTGGC 120

ATCGGGCGAC AGCAGGTCAC AGTGGACGAG GTGTTGGCGG AAGGTGGATT TGCTATTGTA 180

TTTCTGGTGA GGACAAGCAA TGGGATGAAA TGTGCCTTGA AACGCATGTT TGTCAACAAT 240

GAGCATGATC TCCAGGTGTG CAAGAGAGAA ATCCAGATAA TGAGGGACCT TTCAGGGCAC 300

AAGAATATTG TGGGTTACAT TGATTCTAGT ATCAACAACG TGAGTAGCGG TGATGTATGG 360

GAAGTGCTCA TTCTGATGGA CTTTTGTAGA GGTGGCCAGG TGGTAAACCT GATGAACCAG 420

CGCCTGCAAA CAGGCTTTAC AGAGAATGAA GTGCTCCAGA TATTTTGTGA TACCTGTGAA 480

GCTGTTGCCC GCCTGCATCA GTGCAAAACT CCTATTATCC ACCGGGACCT GAAGGTTGAA 540

AACATCCTCT TGCATGACCG AGGCCACTAT GTCCTGTGTG ACTTTGGAAG TGCCACCAAC 600

AAATTCCAGA ATCCACAAAC TGAGGGAGTC AATGCAGTAG AAGATGAGAT TAAGAAATAC 660

ACAACGCTGT CCTATCGAGC ACCAGAAATG GTCAACCTGT ACAGTGGCAA AATCATCACT 720

ACGAAGGCAG ACATTTGGGC TCTTGGATGT TTGTTGTATA AATTATGCTA CTTCACTTTG 780

CCATTTGGGG AAAGTCAGGT GGCAATTTGT GATGGAAACT TCACAATTCC TGATAATTCT 840

CGATATTCTC AAGACATGCA CTGCCTAATT AGGTATATGT TGGAACCAGA CCCTGACAAA 900

AGGCCGGATA TTTACCAGGT GTCCTACTTC TCATTTAAGC TACTCAAGAA AGAGTGCCCA 960

ATTCCAAATG TACAGAACTC TCCCATTCCT GCAAAGCTTC CTGAACCAGT GAAAGCCAGT 1020

GAGGCAGCTG CAAAAAAGAC CCAGCCAAAG GCCAGACTGA CAGATCCCAT TCCCACCACA 1080

GAGACTTCAA TTGCACCCCG CCAGAGGCCT AAAGCTGGGC AGACTCAGCC GAACCCAGGA 1140

ATCCTTCCCA TCCAGCCAGC CCTGACACCC CGGAAGAGGG CCACTGTTCA GCCCCCACCT 1200

CAGGCTGCAG GATCCAGCAA TCAGCCTGGC CTTTTAGCCA GTGTTCCCCA ACCAAAACCC 1260

CAAGCCCCAC CCAGCCAGCC TCTGCCACAA ACTCAGGCCA AGCAGCCACA GGCTCCTCCC 1320

ACTCCACAGC AGACGCCTTC TACTCAGGCC CAGGGTCTGC CTGCTCAGGC CCAGGCCACA 1380

CCCCAGCACC AGCAGCAACT CTTCCTCAAG CAGCAACAGC AGCAGCAACA GCCACCGCCA 1440

CCACAGCAGC AGCCGGCAGG CACGTTTTAC CAGCAGCAGC AGCAGGCCCA GACTCAGCAG 1500

TTTCAGGCAG TACATCCAGC AACCCAGCAA CCAGCAATTG CTCAGTTCCC TGTGGTGTCC 1560

CAAGGAGGCT CTCAACAGCA GCTAATGCAG AATTTCTACC AGCAGCAGCA GCAGCAACAA 1620

CAACAACAGC AACAGCAACA GCTGGCCACA GCCCTGCATC AACAACAGCT GATGACTCAG 1680

CAGGCTGCCT TGCAGCAAAA GCCCACTGTG GCAGCAGGAC AGCAGCCCCA GCCACAGCCA 1740

GCTGCAGCCC CACAGCCAGC GCCTGCCCAG GAGCCAGCGA TTCAAGCCCC AGTAAGACAA 1800

CAGCCAAAGG TTCAGACAAC CCCACCTCCT GCCGTCCAGG GGCAGAAAGT TGGATCTCTC 1860

ACTCCACCCT CGTCCCCCAA AACCCAACGT GCTGGGCACA GGCGTATTCT CAGTGACGTA 1920

ACCCACAGTG CAGTCTTTGG GGTCCCTGCC AGCAAATCAA CCCAGCTGCT CCAGGCAGCT 1980

GCAGCTGAGG CCAGTCTCAA TAAGTCCAAG TCTGCAACCA CCACTCCTTC AGGCTCTCCT 2040

CGGACCTCTC AACAAAACGT TTATAATCCT TCAGAAGGGT CTACGTGGAA TCCCTTCGAT 2100

GACGATAATT TCTCCAAACT CACAGCTGAA GAACTGCTAA ACAAGGACTT TGCCAAGCTG 2160

GGGGAAGGCA AACATCCCGA GAAGCTTGGA GGCTCAGCTG AGAGTTTGAT CCCAGGCTTT 2220

CAATCAACCC AAGGTGATGC TTTTGCTACG ACCTCATTTT CTGCTGGAAC TGCTGAAAAA 2280

AGGAAGGGTG GGCAGACTGT GGACTCTGGC CTCCCGCTTC TAAGCGTGTC TGATCCTTTC 2340

ATTCCTCTTC AAGTACCTGA TGCACCAGAA AAACTAATTG AGGGACTCAA ATCTCCTGAC 2400

ACTTCTCTTC TGCTCCCTGA CCTCTTGCCT ATGACAGATC CTTTTGGTAG CACTTCCGAT 2460

GCTGTAATTG AAAAAGCTGA TGTTGCTGTT GAGAGTCTCA TACCAGGACT GGAGCCCCCA 2520

GTTCCCCAGC GCCTCCCATC TCAGACGGAA TCTGTGACCT CGAATCGCAC AGATTCTCTC 2580

ACCGGGGAAG ATTCCCTGCT TGATTGCTCT CTGCTCTCTA ACCCTACTAC TGACCTTCTG 2640

GAAGAGTTTG CCCCCACAGC AATCTCTGCT CCAGTCCATA AAGCTGCAGA AGATAGTAAT 2700

CTCATCTCAG GTTTTGATGT CCCTGAGGGC TCGGACAAGG TGGCTGAAGA TGAGTTTGAC 2760

CCTATTCCTG TATTGATAAC CAAAAACCCA CAAGGTCTCC AGAGAGAGTC CAATCCCTGT 2820

CCTGTAATAA CTGTAGAGCA CTTTAAAGAA TCACTGGGCG TTAAAGGCCT TCCTCTGTAT 2880

CCAGACCCCT CCAGAGTACC TGGCACAAAG ACTCAGAACA ACTTAGAATC TGACTACTTG 2940

GCCAGAGATG GCCCTTCAAG CAACAGCTCA TTCCACAGCA GCGAAGAGGA AGGGACTGAC 3000

CTTGAAGGAG ACATGCTGGA CTGCAGTGGG TCTCGGCCTC TCCTTATGGA GTCTGAAGAA 3060

GAAGATGAGA GCTGCAGACC CCCCCAGGGG AAGCTGGGAG GAGTCGTTCC ATTTGTTCCA 3120

CCAGAAGTCT CTCCTGAGCA AGCAAAGACA GTGCAAGGTG GAAGAAAGAA CCAGTTTCAA 3180

GCCCTCACAC AGCCAGCCAC TGATGGGCTC AGTGAGCCAG ATGTTTTTGC CATAGCTCCC 3240

TTCAGGAGCT CAAGGGTTCC AAATGATGAC ATGGACATTT TCTCCAAAGC CCCATTTGTC 3300

TCCAAGAGCA GTATGGCTCC TTCCCAGCCA GAGGAGTCAG ACGTGTTTTT GAGAGCTCCT 3360

TTCACTAAGA AGAAAAGCAT GGAGGAGTTA ACAGTTATCC AGAGCACCTC CCAGGAGCTG 3420

CCTGCACAGA CCGGTCTCCT CAGTCAGACA GGTGACGTCC CCCTGCCCGT GGGCCGTGAG 3480

AGAGCTGTGT ACACCTCTGT CCAAGCTCAG TATTCCACAG CTGGTTTTGT GCAACAGTCT 3540

AACCTCCTCT CCCATTCTGT ACAAGCAGCA GACCATCTGG ACAGCATCTC TCCCAGGGGA 3600

TCCTGCCTGG AATCTGGGGG TCATTCTAAT GACAGAAACA AAGGACCTCA GCTCCAGAAA 3660

GAAGCTGTCT CAGGCCCCAT GGCTGGCAAA CCATTCCGCC CCCAGTCCTT ATCCAAGTAT 3720

TCCCGTCACT ATAGCCCAGA AGACGAGCCA AGTCCAGAAG CCCAGCCCAT TGCTGCCTAC 3780

AAAATTGTTT CACAAACCAA CAAGCAGTCG ATAGCTGGGT CTGTTTCTAT CACATCCCTT 3840

TCCTCCAGGA CTACGGAGCT GCCAGCTGCT GATCCATTTG CTTTAGCACC CTTCCCTTCA 3900

AAATCAGGCA AGAAACCCTA G 3921

Domain Profile

S: 1     vriekvlaeGGfalvylaedastgekyalKrilvneeedleeikrEieimkklsghkniv  60

         v++++vlaeGGfa+v+l++ +s+g k+alKr++vn+e+dl+ +krEi+im++lsghkniv

Q: 46    VTVDEVLAEGGFAIVFLVR-TSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIV  104

         6899***************.99**************************************

S: 61    klvdssvkeekdngskevlllleyckkgslvdllnkrlekgelseaeilkilldvtrava  120

          ++dss+++ ++++++evl+l+++c+ g++v+l+n+rl++g ++e+e+l+i++d+++ava

Q: 105   GYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTG-FTENEVLQIFCDTCEAVA  163

         ************9***************************9.******************

S: 121   alHalsvpliHRDlkveNillsdegelvlcDlGSattaileveskqelsalqeeiekntt  180

         +lH++++p+iHRDlkveNill+d+g++vlcD+GSat+++++++ +++++a+++ei+k+tt

Q: 164   RLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQ-TEGVNAVEDEIKKYTT  222

         *******************************************.9***************

S: 181   lsyrsPElidlysnlvideksDiWaLGcllYklcffesPfeesvklailngkysiPensr  240

         lsyr+PE+++lys+++i++k+DiWaLGcllYklc+f+ Pf+es ++ai++g+++iP+nsr

Q: 223   LSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPFGES-QVAICDGNFTIPDNSR  281

         *******************************************.****************

S: 241   yseklkslikkmlevdpeeRptiaqvle  268

         ys+++++li++mle+dp++Rp+i+qv++

Q: 282   YSQDMHCLIRYMLEPDPDKRPDIYQVSY  309

         **************************87

Domain Sequence
(FASTA)

VTVDEVLAEG GFAIVFLVRT SNGMKCALKR MFVNNEHDLQ VCKREIQIMR DLSGHKNIVG 60

YIDSSINNVS SGDVWEVLIL MDFCRGGQVV NLMNQRLQTG FTENEVLQIF CDTCEAVARL 120

HQCKTPIIHR DLKVENILLH DRGHYVLCDF GSATNKFQNP QTEGVNAVED EIKKYTTLSY 180

RAPEMVNLYS GKIITTKADI WALGCLLYKL CYFTLPFGES QVAICDGNFT IPDNSRYSQD 240

MHCLIRYMLE PDPDKRPDIY QVSY 264

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>