EKS-POA-00200

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-POA-00200

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	519.7	1.5E-156	4	286	283

Status

Unreviewed

Ensembl Protein

ENSPPYP00000013932

UniProt Accession

H2P6F6;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL4

Gene Synonyms/Alias

CDKL4;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPPYG00000012473	ENSPPYP00000013932	ENSPPYT00000014497

Organism

Pongo abelii

Functional Description

Protein Length

379

Protein Sequence
(FASTA)

MEKYEKLAKI GEGSYGVVFK CRNKTSGQVV AIKKFVESED DPVVKKIALR EIRTLKQLKH 60

PNLVNLIEVF RRKRKMHLVF EYCDHTLLNE LERNPNGVAD GVIKSVLWQT LQALNFCHIH 120

NCIHRDVKPE NILITKQGII KICDFGFARI LIPGDAYTDY VATRWYRAPE LLVGDTQYGS 180

SVDIWAIGCV FAELLTGQPL WPGKSDVDQL YLIIRTLGKL IPRHQSIFKS NQFFHGISIP 240

EPEDMETLEE KFSDAHPVAL NFMKGCLKMN PDDRLTCSQL LESSYFDSFQ EDQIKRKARN 300

EGRNRRRQQQ APKSAFPRLF LKTKICQVQR NETQTSGNQI LPNGPILQNS MVTLMTNINS 360

AIYQVTVLHL LSENFEVKS 379

Nucleotide Sequence
(FASTA)

ATGGAAAAGT ATGAAAAATT AGCTAAGATT GGAGAAGGGT CTTATGGGGT TGTATTCAAA 60

TGCAGAAACA AAACCTCTGG ACAAGTAGTA GCTATTAAAA AATTTGTGGA ATCTGAAGAT 120

GATCCTGTTG TTAAGAAAAT AGCACTAAGA GAAATACGTA CGTTGAAGCA ATTAAAACAT 180

CCAAATCTTG TGAACCTCAT TGAGGTGTTC AGGAGAAAAA GGAAAATGCA TTTAGTTTTT 240

GAATACTGTG ATCATACACT TTTAAATGAG CTGGAAAGAA ACCCAAATGG AGTTGCTGAT 300

GGAGTGATCA AAAGTGTATT ATGGCAAACA CTTCAAGCTC TTAATTTCTG TCATATACAT 360

AACTGTATTC ACAGAGATGT AAAACCTGAA AATATTCTAA TAACTAAGCA AGGAATAATC 420

AAGATTTGTG ACTTTGGGTT TGCACGAATT CTGATTCCAG GAGATGCCTA CACCGATTAT 480

GTAGCTACGA GATGGTACCG AGCTCCTGAA CTTCTTGTGG GAGATACTCA GTATGGTTCT 540

TCAGTCGATA TATGGGCTAT TGGTTGCGTT TTTGCAGAGC TCCTGACAGG CCAGCCACTG 600

TGGCCTGGAA AATCAGATGT GGACCAACTT TATCTGATAA TCAGAACACT AGGAAAATTA 660

ATCCCAAGAC ATCAATCAAT CTTTAAAAGT AACCAGTTTT TCCATGGCAT CAGTATACCT 720

GAACCAGAAG ACATGGAAAC TCTTGAGGAA AAGTTCTCAG ATGCTCATCC TGTGGCTCTG 780

AACTTCATGA AGGGGTGTCT GAAGATGAAT CCAGATGACA GATTAACCTG TTCCCAACTC 840

CTGGAGAGCT CCTACTTTGA TTCTTTTCAA GAGGACCAAA TTAAAAGAAA AGCACGTAAT 900

GAAGGAAGAA ACAGAAGACG CCAGCAGCAG GCACCTAAGT CTGCCTTTCC TAGGCTTTTT 960

CTCAAAACCA AGATCTGCCA GGTACAAAGG AATGAAACCC AGACGTCTGG GAACCAAATT 1020

CTACCCAATG GGCCAATATT GCAGAACAGT ATGGTGACTC TTATGACAAA CATTAATTCT 1080

GCAATTTATC AGGTGACTGT CCTTCACTTG CTTTCAGAAA ACTTTGAAGT TAAATCGTAA 1140

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         yekl+k+GeGsyGvv+kcrnk++gq+vaikkf+esedd++vkkialrei+ lkqlkh+nl

Q: 4     YEKLAKIGEGSYGVVFKCRNKTSGQVVAIKKFVESEDDPVVKKIALREIRTLKQLKHPNL  63

         9***********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnl+evfrrk+k++lvfey+d+t+l+eler+pnGv + ++k++l+q+l+a++fch +n+i

Q: 64    VNLIEVFRRKRKMHLVFEYCDHTLLNELERNPNGVADGVIKSVLWQTLQALNFCHIHNCI  123

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrd+kpenili+k+g++k+cdfGfar+l+ pgd+ytdyvatrwyrapellvgdt+yG+sv

Q: 124   HRDVKPENILITKQGIIKICDFGFARILI-PGDAYTDYVATRWYRAPELLVGDTQYGSSV  182

         *****************************.******************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         d+waiGc++aelltG+pl+pgksdvdqly+i++tlG+liprhq+if++n++f+G+++pe+

Q: 183   DIWAIGCVFAELLTGQPLWPGKSDVDQLYLIIRTLGKLIPRHQSIFKSNQFFHGISIPEP  242

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         ed+e+le+k++++++v+l+++k+clk++p++rl+c++ll+++yf

Q: 243   EDMETLEEKFSDAHPVALNFMKGCLKMNPDDRLTCSQLLESSYF  286

         ******************************************98

Domain Sequence
(FASTA)

YEKLAKIGEG SYGVVFKCRN KTSGQVVAIK KFVESEDDPV VKKIALREIR TLKQLKHPNL 60

VNLIEVFRRK RKMHLVFEYC DHTLLNELER NPNGVADGVI KSVLWQTLQA LNFCHIHNCI 120

HRDVKPENIL ITKQGIIKIC DFGFARILIP GDAYTDYVAT RWYRAPELLV GDTQYGSSVD 180

IWAIGCVFAE LLTGQPLWPG KSDVDQLYLI IRTLGKLIPR HQSIFKSNQF FHGISIPEPE 240

DMETLEEKFS DAHPVALNFM KGCLKMNPDD RLTCSQLLES SYF 283

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Equus caballus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Tursiops truncatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

pon:100458367

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013