EKS-POA-00179

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-POA-00179

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NRBP	541.0	5.5E-163	103	366	264

Status

Reviewed

Ensembl Protein

ENSPPYP00000014013

UniProt Accession

Q5RBH9;

Protein Name

Nuclear receptor-binding protein

Protein Synonyms/Alias

Gene Name

NRBP1

Gene Synonyms/Alias

NRBP1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPPYG00000012546	ENSPPYP00000014013	ENSPPYT00000014580

Organism

Pongo abelii

Functional Description

May play a role in subcellular trafficking between theendoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases (By similarity).

Protein Length

573

Protein Sequence
(FASTA)

SCEGVAVIRG PGTRAGAEAE AQAAGRGVGS AGLSVPSSMS EGESQTVLSS GSDPKVESSS 60

SAPGLTSVSP PVTSTTSAAS PEEEEESEDE SEILEESPCG RWQKRREEVN QRNVPGIDSA 120

YLAMDTEEGV EVVWNEVQFS ERKNYKLQEE KVRAVFDNLI QLEHLNIVKF HKYWADIKEN 180

KARVIFITEY MSSGSLKQFL KKTKKNHKTM NEKAWKRWCT QILSALSYLH SCDPPIIHGN 240

LTCDTIFIQH NGLIKIGSVA PDTINNHVKT CREEQKNLHF FAPEYGEVTN VTTAVDIYSF 300

GMCALEMAVL EIQGNGESSY VPQEAISSAI QLLEDPLQRE FIQKCLQSEP ARRPTARELL 360

FHPALFEVPS LKLLAAHCIV GHQHMIPENA LEEITKNMDT SAVLAEIPAG PGREPVQTLY 420

SQSPALELDK FLEDVRNGIY PLTAFGLPRP QQPQQEEVTS PVVPPSVKTP TPEPAEVETR 480

KVVLMQCNIE SVEEGVKHHL TLLLKLEDKL NRHLSCDLMP NENIPELAAE LVQLGFISEA 540

DQSRLTSLLE ETLNKFNFAR SSTLNSAAVT VSS 573

Nucleotide Sequence
(FASTA)

AGCTGTGAGG GAGTCGCTGT GATCCGGGGC CCCGGAACCC GAGCTGGAGC TGAAGCTGAA 60

GCGCAGGCTG CGGGGCGCGG AGTCGGGAGT GCAGGCCTGA GTGTTCCTTC CAGCATGTCG 120

GAGGGGGAGT CCCAGACAGT ACTTAGCAGT GGCTCAGACC CAAAGGTAGA ATCCTCATCT 180

TCAGCTCCTG GCCTGACATC AGTGTCACCT CCTGTGACCT CCACAACCTC AGCTGCTTCC 240

CCAGAGGAAG AAGAAGAAAG TGAAGATGAG TCTGAGATTT TGGAAGAGTC GCCATGTGGG 300

CGCTGGCAGA AGAGGCGAGA AGAGGTGAAT CAACGGAATG TACCAGGTAT TGACAGTGCA 360

TACCTGGCCA TGGATACAGA GGAAGGTGTA GAGGTTGTGT GGAATGAGGT ACAGTTCTCT 420

GAGCGCAAGA ACTACAAGCT GCAGGAGGAA AAGGTTCGTG CTGTGTTTGA TAATCTGATT 480

CAGTTGGAGC ATCTTAACAT TGTTAAGTTT CACAAATACT GGGCTGACAT TAAAGAGAAC 540

AAGGCCAGGG TCATTTTTAT CACAGAATAC ATGTCATCTG GGAGTCTGAA GCAATTTCTG 600

AAGAAGACCA AAAAGAACCA CAAGACCATG AATGAAAAGG CATGGAAGCG TTGGTGCACA 660

CAAATCCTCT CTGCCCTAAG CTACCTGCAC TCCTGTGACC CCCCCATCAT CCATGGGAAC 720

CTGACCTGTG ACACCATCTT CATCCAGCAC AACGGACTCA TCAAGATTGG CTCTGTGGCT 780

CCTGACACTA TCAACAATCA TGTGAAGACT TGTCGAGAAG AGCAGAAGAA TCTACACTTC 840

TTTGCACCAG AGTATGGAGA AGTCACTAAT GTGACAACAG CAGTGGACAT CTACTCCTTC 900

GGCATGTGTG CACTGGAGAT GGCAGTGCTG GAGATTCAGG GCAATGGAGA GTCCTCATAT 960

GTGCCACAGG AAGCCATCAG CAGTGCCATC CAGCTTCTAG AAGACCCATT ACAGAGGGAG 1020

TTCATTCAAA AGTGCCTGCA GTCTGAGCCT GCTCGCAGAC CAACAGCCAG AGAACTTCTG 1080

TTCCACCCAG CATTGTTTGA AGTGCCCTCG CTCAAACTCC TTGCTGCCCA CTGCATTGTG 1140

GGACACCAAC ACATGATCCC AGAGAACGCT CTGGAGGAGA TAACCAAAAA CATGGATACC 1200

AGTGCCGTTC TGGCTGAAAT CCCTGCAGGA CCAGGAAGAG AACCAGTTCA GACTTTGTAC 1260

TCTCAGTCAC CAGCTCTGGA ATTAGATAAA TTCCTTGAAG ATGTCAGGAA TGGGATCTAT 1320

CCTCTGACAG CCTTTGGGTT GCCTCGGCCC CAGCAGCCAC AGCAGGAGGA GGTGACATCA 1380

CCTGTTGTGC CCCCCTCTGT CAAGACTCCG ACACCTGAAC CAGCTGAGGT GGAGACTCGC 1440

AAGGTGGTGC TGATGCAGTG CAACATTGAG TCGGTGGAGG AGGGAGTCAA ACACCACCTG 1500

ACGCTTCTGC TGAAGTTGGA GGACAAACTG AACCGGCACC TGAGCTGTGA CCTGATGCCA 1560

AATGAGAATA TCCCTGAGTT GGCGGCTGAG CTGGTGCAGC TGGGCTTCAT TAGTGAGGCT 1620

GACCAGAGCC GGTTGACTTC TCTGCTAGAA GAGACCTTGA ACAAGTTCAA TTTTGCCAGG 1680

AGCAGTACCC TCAACTCAGC CGCTGTCACC GTCTCCTCTT AG 1722

Domain Profile

S: 1     qkrreevnqrdvpgidsaylamdteegvevvwnevqfserkefkaqeekiravfdnlvql  60

         qkrreevnqr+vpgidsaylamdteegvevvwnevqfserk++k+qeek+ravfdnl+ql

Q: 103   QKRREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQL  162

         89**********************************************************

S: 61    dhlnivklhkywldtkeakarvifiteyvssgslkqflkktkknakalnakawkrwctqi  120

         +hlnivk+hkyw+d+ke+karvifitey+ssgslkqflkktkkn+k++n+kawkrwctqi

Q: 163   EHLNIVKFHKYWADIKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQI  222

         ************************************************************

S: 121   lsalsylhscdppiihgnltcdtifiqhnglikigsvlpdairssvkaereelrnlhffa  180

         lsalsylhscdppiihgnltcdtifiqhnglikigsv+pd+i+++vk++ree++nlhffa

Q: 223   LSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVAPDTINNHVKTCREEQKNLHFFA  282

         ************************************************************

S: 181   peygevtelttavdiysfglcalelavleiqgngess.vteeaieraiksledplqrefi  239

         peygevt++ttavdiysfg+cale+avleiqgngess v++eai++ai++ledplqrefi

Q: 283   PEYGEVTNVTTAVDIYSFGMCALEMAVLEIQGNGESSyVPQEAISSAIQLLEDPLQREFI  342

         ************************************99**********************

S: 240   rkclakdparrpsarellfhrvlf  263

         +kcl+++parrp+arellfh++lf

Q: 343   QKCLQSEPARRPTARELLFHPALF  366

         **********************98

Domain Sequence
(FASTA)

QKRREEVNQR NVPGIDSAYL AMDTEEGVEV VWNEVQFSER KNYKLQEEKV RAVFDNLIQL 60

EHLNIVKFHK YWADIKENKA RVIFITEYMS SGSLKQFLKK TKKNHKTMNE KAWKRWCTQI 120

LSALSYLHSC DPPIIHGNLT CDTIFIQHNG LIKIGSVAPD TINNHVKTCR EEQKNLHFFA 180

PEYGEVTNVT TAVDIYSFGM CALEMAVLEI QGNGESSYVP QEAISSAIQL LEDPLQREFI 240

QKCLQSEPAR RPTARELLFH PALF 264

Keyword

Acetylation; Cell projection; Complete proteome; Cytoplasm; Membrane; Phosphoprotein; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005938	; C:cell cortex
GO:0012505	; C:endomembrane system
GO:0030027	; C:lamellipodium
GO:0016020	; C:membrane
GO:0048471	; C:perinuclear region of cytoplasm
GO:0016772	; F:transferase activity, transferring phosphorus-containing groups
GO:0006888	; P:ER to Golgi vesicle-mediated transport
GO:0006468	; P:protein phosphorylation

KEGG

pon:100172412

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS50011

; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013