EPS-POA-00036

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-POA-00036

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	169.6	1.1E-49	278	471	194

Status

Unreviewed

Ensembl Protein

ENSPPYP00000014014

UniProt Accession

H2P6N4;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1G

Gene Synonyms/Alias

PPM1G;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPPYG00000012547	ENSPPYP00000014014	ENSPPYT00000014581

Organism

Pongo abelii

Functional Description

Protein Length

515

Protein Sequence
(FASTA)

MQGWRVSMED AHNCIPELDS ETAMFSVYDG HGGEEVALYC AKYLPDIIKD QKAYKEGKLQ 60

KALEDAFLAI DAKLTTEEVI KELAQIAGRP TEDEDEKEKV ADEDDVDNEE AALLHEEATM 120

TIEELLTRYG QNCHKGPPHS KSGAGTGEEP GSQGLNGEAG PEDSTRETPS QENGPTAKAY 180

TGFSSNSERG TEAGQVGEPG IPTGEAGPSC SSASDKLPRV AKSKFFEDSE DESDEAEEEE 240

EDSEECSEEE DGYSSEEAEN EEDEDDTEEA EEDDEEEEEE MMVPGMEGKE EPGSDSGTTA 300

VVALIRGKQL IVANAGDSRC VVSEAGKALD MSYDHKPEDE VELARIKNAG GKVTMDGRVN 360

GGLNLSRAIG DHFYKRNKNL PPEEQMISAL PDIKVLTLTD DHEFMVIACD GIWNVMSSQE 420

VVDFIQSKIS QRDENGELRL LSSIVEELLD QCLAPDTSGD GTGCDNMTCI IICFKPRNTA 480

ELQPESGKRK LEEVLSTEGA EENGNSDKKK KAKRD 515

Nucleotide Sequence
(FASTA)

ATGCAAGGCT GGCGCGTCTC CATGGAGGAT GCTCACAACT GTATTCCAGA GCTGGACAGT 60

GAGACAGCCA TGTTTTCTGT CTACGATGGA CATGGAGGGG AGGAAGTTGC CTTGTACTGT 120

GCCAAATATC TTCCTGATAT CATCAAAGAT CAGAAGGCCT ACAAGGAAGG CAAGCTGCAG 180

AAGGCTTTAG AAGATGCCTT CTTGGCTATT GATGCCAAAC TGACCACTGA GGAAGTCATT 240

AAAGAGCTGG CACAGATTGC AGGGCGACCC ACTGAGGATG AAGATGAAAA AGAAAAAGTA 300

GCTGATGAAG ATGATGTGGA CAATGAGGAG GCTGCACTGC TGCATGAAGA GGCTACCATG 360

ACTATTGAAG AGCTGCTGAC ACGCTACGGG CAGAACTGTC ACAAGGGCCC TCCCCACAGC 420

AAATCTGGAG CTGGGACAGG CGAGGAACCA GGGTCCCAGG GCCTCAATGG GGAGGCAGGA 480

CCTGAGGACT CAACTAGGGA AACTCCTTCA CAGGAAAATG GCCCCACAGC CAAGGCCTAC 540

ACAGGCTTTT CCTCCAACTC GGAACGTGGG ACTGAGGCAG GCCAAGTTGG TGAGCCTGGC 600

ATTCCCACTG GTGAGGCTGG GCCTTCCTGC TCTTCAGCCT CTGACAAGCT GCCTCGAGTT 660

GCTAAGTCCA AGTTCTTTGA GGACAGTGAG GATGAGTCAG ATGAGGCGGA GGAGGAAGAG 720

GAAGACAGTG AGGAATGCAG CGAGGAAGAG GATGGCTACA GCAGTGAGGA GGCAGAGAAT 780

GAGGAAGATG AGGATGACAC CGAGGAGGCT GAAGAGGACG ATGAAGAAGA AGAAGAAGAG 840

ATGATGGTGC CAGGGATGGA AGGCAAAGAG GAGCCTGGCT CTGACAGTGG TACAACAGCG 900

GTGGTGGCCC TGATACGAGG GAAGCAGTTG ATTGTAGCCA ACGCAGGAGA CTCTCGCTGT 960

GTGGTATCTG AGGCTGGCAA AGCTTTAGAC ATGTCCTATG ATCACAAACC AGAGGATGAA 1020

GTAGAACTAG CACGCATCAA GAATGCTGGT GGCAAGGTCA CCATGGATGG GCGAGTCAAC 1080

GGGGGCCTCA ACCTCTCCAG AGCCATTGGG GACCACTTCT ATAAGAGAAA CAAGAACCTG 1140

CCACCTGAGG AACAGATGAT TTCAGCCCTT CCTGACATCA AGGTGCTGAC TCTCACTGAC 1200

GACCATGAAT TCATGGTCAT TGCCTGTGAT GGCATCTGGA ATGTGATGAG CAGCCAGGAA 1260

GTTGTAGATT TCATTCAATC AAAGATCAGC CAGCGTGATG AAAATGGGGA GCTTCGGTTA 1320

TTGTCATCCA TTGTGGAAGA GCTGCTGGAT CAGTGCCTGG CACCAGACAC TTCTGGGGAT 1380

GGTACAGGGT GTGACAACAT GACCTGCATC ATCATTTGCT TCAAGCCCCG AAACACAGCA 1440

GAGCTCCAGC CAGAGAGTGG CAAGCGAAAA CTAGAGGAGG TGCTCTCTAC TGAGGGGGCT 1500

GAAGAAAATG GCAACAGCGA CAAGAAGAAG AAGGCCAAGC GGGACTAG 1548

Domain Profile

S: 87    deel..kvleeksldidksGstavvalikdsklyvanvGdSravLcrngkavelssdHkp  144

         +ee+    +e k++  + sG+tavvali++++l+van+GdSr+v +  gka+ +s dHkp

Q: 278   EEEMmvPGMEGKEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKP  337

         344413234444445566******************************************

S: 145   sredEleRieeaggsvilkdgaRvlGvLavsRalGdlylk.........pyvtpePevts  195

         + e El+Ri++agg+v+ +   Rv+G L++sRa+Gd ++k         +++++ P++ +

Q: 338   EDEVELARIKNAGGKVTMDG--RVNGGLNLSRAIGDHFYKrnknlppeeQMISALPDIKV  395

         *******************9..**************************************

S: 196   hrltsedefliLasDGlwdvvsneeavslvrdvle......kkeaeqeaakkLvklalar  249

          +lt ++ef+++a+DG+w+v+s++e+v+++++ ++      + + ++++ ++L++++la

Q: 396   LTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISqrdengELRLLSSIVEELLDQCLAP  455

         ********************************9998877666667788999999999999

S: 250   gsk......dnvsaiv  259

          ++      dn++ i+

Q: 456   DTSgdgtgcDNMTCII  471

         9987777777777766

Domain Sequence
(FASTA)

EEEMMVPGME GKEEPGSDSG TTAVVALIRG KQLIVANAGD SRCVVSEAGK ALDMSYDHKP 60

EDEVELARIK NAGGKVTMDG RVNGGLNLSR AIGDHFYKRN KNLPPEEQMI SALPDIKVLT 120

LTDDHEFMVI ACDGIWNVMS SQEVVDFIQS KISQRDENGE LRLLSSIVEE LLDQCLAPDT 180

SGDGTGCDNM TCII 194

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0046872	; F:metal ion binding
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0007050	; P:cell cycle arrest
GO:0035970	; P:peptidyl-threonine dephosphorylation

KEGG

InterPros

IPR001932	; PP2C-like.
IPR000222	; PP2C_Mn2_Asp60_BS.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481

; PP2C; 2.

SMARTs

SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

PS01032

; PP2C; 1.

Prints

Created Date

20-Feb-2013