EKS-POA-00380

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-POA-00380

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE11	363.9	6.1E-109	372	632	261

Status

Unreviewed

Ensembl Protein

ENSPPYP00000014245

UniProt Accession

H2P7A4;

Protein Name

Protein Synonyms/Alias

Gene Name

MAP3K2

Gene Synonyms/Alias

MAP3K2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPPYG00000012768	ENSPPYP00000014245	ENSPPYT00000014825

Organism

Pongo abelii

Functional Description

Protein Length

635

Protein Sequence
(FASTA)

WENHFPNFQI VELFAIMDDQ QALNSIMQDL AVLHKASRPA LSLQETRKAK SSSPKKQNDV 60

RVKFEHRGEK RILQFPRPVK LEDLRSKAKI AFGQSMDLHY TNNELVIPLT TQDDLDKAVE 120

LLDRSIHMKS LKILLVINGS TQATNLEPLP SLEDLDNTVF GAERKKRLPI IGHTSRDRSS 180

PPPGYIPDEL HQVARNGSFT SINSEGEFIP ESMDQMLDPL SLSSPENSGS GSCPSLDSPL 240

DGESYPKSRM PRAQSYPDNH QEFSDYDNPI FEKFGKGGTY PRRYHVSYHH QEYNDGRKTF 300

PRARRTQGTS LRSPVSFSPT DHSLSTSSGS SIFTPEYDDS RIRRRGSDID NPTLTVMDIS 360

PPSRSPRAPT NWRLGKLLGQ GAFGRVYLCY DVDTGRELAV KQVQFDPDSP ETSKEVNALE 420

CEIQLLKNLL HERIVQYYGC LRDPQEKTLS IFMEYMPGGS IKDQLKAYGA LTENVTRKYT 480

RQILEGVHYL HSNMIVHRDI KGANILRDST GNVKLGDFGA SKRLQTICLS GTGMKSVTGT 540

PYWMSPEVIS GEGYGRKADI WSVACTVVEM LTEKPPWAEF EAMAAIFKIA TQPTNPKLPP 600

HVSDYTRDFL KQIFVEAKLR PSADELLRHM FVHYH 635

Nucleotide Sequence
(FASTA)

TGGGAGAACC ATTTTCCTAA TTTTCAAATT GTTGAGCTAT TTGCCATAAT GGATGATCAG 60

CAAGCTTTGA ACTCAATCAT GCAAGATTTG GCTGTCCTTC ATAAGGCCAG TCGACCAGCA 120

TTATCCTTGC AGGAAACCAG AAAAGCAAAA TCTTCATCAC CAAAAAAACA GAATGATGTC 180

CGAGTCAAAT TTGAACATAG AGGAGAAAAA AGAATCCTTC AGTTCCCCAG ACCAGTTAAA 240

CTGGAAGATC TGAGATCTAA AGCTAAAATT GCCTTTGGAC AGTCTATGGA TCTACATTAT 300

ACCAATAACG AGTTGGTAAT TCCATTAACT ACTCAAGATG ACTTGGACAA AGCTGTGGAA 360

CTGCTGGATC GTAGTATTCA TATGAAGAGC CTCAAGATAT TACTTGTAAT AAATGGAAGT 420

ACACAGGCTA CTAATTTAGA ACCATTGCCA TCACTAGAAG ATTTGGATAA TACAGTATTT 480

GGTGCAGAGA GGAAAAAACG GCTTCCTATA ATAGGTCATA CTAGTAGAGA TAGAAGTTCT 540

CCTCCCCCAG GATACATTCC AGATGAATTA CACCAGGTTG CCCGGAATGG GTCATTCACT 600

AGTATCAACA GTGAAGGAGA GTTCATTCCA GAGAGCATGG ACCAAATGCT GGATCCATTA 660

TCTTTAAGCA GCCCTGAAAA TTCTGGCTCA GGAAGTTGTC CATCACTTGA TAGTCCTTTG 720

GATGGAGAGA GCTATCCAAA ATCACGAATG CCTAGGGCAC AGAGCTACCC AGATAATCAT 780

CAGGAATTTT CAGACTATGA TAACCCTATC TTTGAGAAAT TTGGAAAAGG AGGAACATAT 840

CCAAGAAGGT ATCATGTTTC ATATCATCAT CAAGAGTATA ATGATGGTCG TAAAACTTTT 900

CCAAGAGCTA GAAGGACCCA GGGGACCAGC TTACGGTCTC CTGTGAGTTT CAGTCCTACT 960

GATCATTCCT TAAGCACTAG TAGTGGAAGC AGTATCTTTA CCCCAGAGTA TGATGATAGT 1020

CGAATAAGAA GAAGGGGAAG TGACATAGAC AATCCTACTT TGACCGTAAT GGACATCAGC 1080

CCACCCAGCC GTTCACCTCG AGCTCCGACC AACTGGAGAT TGGGCAAACT GCTTGGCCAG 1140

GGAGCCTTTG GAAGGGTCTA CCTCTGTTAT GATGTTGATA CAGGAAGAGA ATTGGCTGTT 1200

AAGCAAGTTC AATTTGATCC CGACAGTCCT GAGACCAGCA AGGAAGTAAA TGCACTTGAG 1260

TGTGAAATTC AGTTGCTGAA AAACTTGCTA CATGAGCGAA TTGTTCAGTA TTATGGCTGT 1320

TTGAGGGATC CCCAGGAAAA AACACTTTCC ATATTTATGG AATATATGCC AGGGGGTTCA 1380

ATTAAGGACC AATTAAAAGC ATATGGCGCT CTTACTGAGA ATGTGACTAG GAAATACACC 1440

CGTCAGATTC TGGAGGGTGT CCATTATTTG CACAGTAATA TGATTGTCCA TAGAGATATC 1500

AAAGGCGCAA ATATCCTGCG AGATTCAACA GGCAACGTCA AACTAGGAGA TTTTGGGGCC 1560

AGCAAACGGC TTCAGACCAT CTGTCTCTCA GGGACAGGAA TGAAGTCTGT CACAGGCACA 1620

CCATACTGGA TGAGCCCTGA AGTCATCAGT GGAGAAGGCT ATGGAAGAAA AGCAGACATC 1680

TGGAGTGTTG CATGTACTGT GGTAGAAATG CTAACTGAAA AGCCGCCTTG GGCTGAATTT 1740

GAAGCAATGG CTGCCATCTT TAAAATCGCC ACTCAGCCAA CAAACCCAAA GCTGCCACCT 1800

CATGTCTCAG ACTATACTCG AGATTTCCTC AAACAGATTT TTGTAGAGGC CAAACTGAGA 1860

CCTTCAGCTG ATGAACTCTT AAGGCACATG TTTGTGCATT ATCACTAG 1908

Domain Profile

S: 1     wqkrevigkGsfgsvyaaldvdtgellavKeveikpekksekkevkalkeEikllkelkH  60

         w+ ++++g+G+fg+vy+++dvdtg+ lavK+v+++p++ +++kev+al++Ei+llk+l H

Q: 372   WRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNLLH  431

         78899*******************************************************

S: 61    enivkyyGv..eveeeelkiflEyvegGslssllekygkleesvikkytkqileglayLH  118

         e+iv+yyG+  + +e++l+if+Ey++gGs++++l++yg+l+e+v++kyt+qileg++yLH

Q: 432   ERIVQYYGClrDPQEKTLSIFMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLH  491

         *********777899*********************************************

S: 119   ekkivHRDiKgaNilldssgvvklsDFGaskrlaelntkaaelesltGtlaymaPEvikk  178

         +++ivHRDiKgaNil ds+g+vkl+DFGaskrl++++ + + ++s+tGt+++m+PEvi++

Q: 492   SNMIVHRDIKGANILRDSTGNVKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISG  551

         **********************************************************99

S: 179   kekgygrkaDiWslgcvviemltgkrPfaeldeelaimfkvgakktkPeipeklseegkd  238

         +  gygrkaDiWs++c+v+emlt+k+P+ae+ e++a++fk++++ t+P++p ++s+ ++d

Q: 552   E--GYGRKADIWSVACTVVEMLTEKPPWAEF-EAMAAIFKIATQPTNPKLPPHVSDYTRD  608

         8..****************************.9***************************

S: 239   flekcleldpkkrpsaeeLLkhefl  263

         fl++++ +++k rpsa+eLL+h+f+

Q: 609   FLKQIF-VEAKLRPSADELLRHMFV  632

         ******.899*************96

Domain Sequence
(FASTA)

WRLGKLLGQG AFGRVYLCYD VDTGRELAVK QVQFDPDSPE TSKEVNALEC EIQLLKNLLH 60

ERIVQYYGCL RDPQEKTLSI FMEYMPGGSI KDQLKAYGAL TENVTRKYTR QILEGVHYLH 120

SNMIVHRDIK GANILRDSTG NVKLGDFGAS KRLQTICLSG TGMKSVTGTP YWMSPEVISG 180

EGYGRKADIW SVACTVVEML TEKPPWAEFE AMAAIFKIAT QPTNPKLPPH VSDYTRDFLK 240

QIFVEAKLRP SADELLRHMF V 261

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity
GO:0071260	; P:cellular response to mechanical stimulus
GO:0045893	; P:positive regulation of transcription, DNA-dependent

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000270	; OPR_PB1.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF00564	; PB1; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00666	; PB1; 1.
SM00220	; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013