EPS-POA-00019

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-POA-00019

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	81.1	7.6E-23	87	150	64

Status

Unreviewed

Ensembl Protein

ENSPPYP00000014520

UniProt Accession

H2P821;

Protein Name

Protein Synonyms/Alias

Gene Name

DUSP19

Gene Synonyms/Alias

DUSP19;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPPYG00000012997	ENSPPYP00000014520	ENSPPYT00000015109

Organism

Pongo abelii

Functional Description

Protein Length

166

Protein Sequence
(FASTA)

MHSFNQEIKA FSRNNLRKQC TRVTTLTGKK IIETWKDARI HVVEEVEPSS GGGCGYVQDL 60

SSDLQVGVIK PWLLLGSQDA AHDLDILKKN KDGVVLVHCN AGVSRAAAIV IGFLMNSEQT 120

SFTSAFSLVK NARPSICPNS GFMEQLRTYQ EGKESNKCDR IQENSS 166

Nucleotide Sequence
(FASTA)

ATGCACTCCT TTAACCAGGA AATTAAAGCA TTCTCCCGGA ATAATCTCAG GAAGCAATGC 60

ACCAGGGTGA CAACGCTAAC TGGAAAGAAA ATTATAGAAA CATGGAAAGA TGCCAGAATT 120

CATGTTGTGG AAGAAGTAGA GCCGAGCAGT GGGGGTGGTT GTGGTTATGT GCAGGACCTT 180

AGCTCGGACC TGCAGGTTGG CGTTATTAAG CCATGGTTGC TCCTAGGGTC ACAAGATGCT 240

GCTCATGATT TGGATATACT GAAAAAGAAT AAGGATGGAG TGGTTCTTGT TCATTGTAAT 300

GCGGGCGTTT CCAGGGCTGC TGCAATTGTA ATAGGTTTCC TGATGAATTC TGAACAAACC 360

TCATTTACCA GTGCTTTTTC TTTGGTGAAA AATGCAAGAC CTTCCATATG TCCAAATTCT 420

GGCTTCATGG AGCAGCTTCG TACATATCAA GAGGGCAAAG AAAGCAATAA GTGTGACAGA 480

ATACAGGAGA ACAGTTCATG A 501

Domain Profile

S: 82    a.kekggkvlvHCaaGvsRSatlvlaYLmkveglslsdAieavkrkrpsiepnegfleQL  140

           k+k+g vlvHC+aGvsR+a++v+++Lm+ e+ s+++A++ vk+ rpsi+pn+gf+eQL

Q: 87    LkKNKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSICPNSGFMEQL  146

         357899******************************************************

S: 141   lele  144

         ++++

Q: 147   RTYQ  150

         *997

Domain Sequence
(FASTA)

LKKNKDGVVL VHCNAGVSRA AAIVIGFLMN SEQTSFTSAF SLVKNARPSI CPNSGFMEQL 60

RTYQ 64

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0008579	; F:JUN kinase phosphatase activity
GO:0008330	; F:protein tyrosine/threonine phosphatase activity
GO:0000188	; P:inactivation of MAPK activity
GO:0007254	; P:JNK cascade
GO:0006470	; P:protein dephosphorylation

KEGG

InterPros

IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR020422	; Dual-sp_phosphatase_subgr_cat.
IPR024950	; DUSP.
IPR000387	; Tyr/Dual-specificity_Pase.

Pfam

PF00782

; DSPc; 1.

SMARTs

Prosites

PS50056	; TYR_PHOSPHATASE_2; 1.
PS50054	; TYR_PHOSPHATASE_DUAL; 1.

Prints

Created Date

20-Feb-2013