EKS-POA-00407

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-POA-00407

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/DAPK	437.5	1.5E-131	35	293	259

Status

Unreviewed

Ensembl Protein

ENSPPYP00000014566

UniProt Accession

H2P866;

Protein Name

Protein Synonyms/Alias

Gene Name

STK17B

Gene Synonyms/Alias

STK17B;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPPYG00000013037	ENSPPYP00000014566	ENSPPYT00000015155

Organism

Pongo abelii

Functional Description

Protein Length

372

Protein Sequence
(FASTA)

MSRRRFDCRS ISGLVTTTPQ IPMKMENFNN FYILTSKELG RGKFAVVRQC ISKSTGQEYA 60

AKFLKKRRRG QDCRAEILHE IAVLELAKSC PRVINLHEVY ENTSEIILIL EYAAGGEIFN 120

LCLPELAEMV SENDVIRLIK QILEGVYYLH QNNIVHLDLK PQNILLSSIY PLGDIKIVDF 180

GMSRKIGHAC ELREIMGTPE YLAPEILNYD PITTATDMWN IGIIAYMLLT HTSPFVGEDN 240

QETYLNISQV NVDYSEETFS SVSQLATDFI QSLLVKNPEK RPTAEICLSH SWLQQWDFEN 300

LFHPEETSSS SQTQDHSIRS SEDKTSKSSC NGTCGDREDK ENIPEDSSMV SKRFRFDDSL 360

PNPHELVSDL LC 372

Nucleotide Sequence
(FASTA)

ATGTCGAGGA GGAGATTTGA TTGCCGAAGT ATTTCAGGCC TAGTAACTAC AACTCCTCAA 60

ATTCCAATGA AAATGGAAAA CTTTAATAAT TTCTATATAC TTACATCTAA AGAGCTAGGG 120

AGAGGAAAAT TTGCTGTGGT TAGACAATGT ATATCAAAAT CTACTGGCCA AGAATATGCT 180

GCAAAATTTC TAAAAAAGAG AAGAAGAGGA CAGGATTGTC GAGCAGAGAT TTTACATGAG 240

ATTGCTGTGC TTGAATTGGC AAAGTCTTGT CCCCGTGTTA TTAATCTTCA TGAGGTCTAT 300

GAAAATACAA GTGAAATCAT TTTGATATTG GAATATGCTG CAGGTGGAGA AATTTTCAAC 360

CTGTGTTTAC CTGAGTTGGC TGAAATGGTT TCTGAAAATG ATGTTATCAG ACTTATTAAA 420

CAAATACTTG AAGGAGTTTA TTATCTACAT CAGAATAACA TTGTACACCT TGATTTAAAG 480

CCACAGAATA TATTACTGAG CAGCATATAC CCTCTCGGGG ACATTAAAAT AGTAGATTTT 540

GGAATGTCTC GAAAAATAGG GCATGCGTGT GAACTTCGGG AAATCATGGG AACACCAGAA 600

TATTTAGCTC CAGAAATCCT GAACTATGAT CCCATTACCA CAGCAACAGA TATGTGGAAT 660

ATTGGTATAA TAGCATATAT GTTGTTAACT CACACATCAC CATTTGTGGG AGAAGATAAT 720

CAAGAAACAT ACCTCAATAT TTCTCAAGTT AATGTAGATT ATTCAGAAGA AACTTTTTCA 780

TCAGTTTCAC AGCTGGCCAC AGACTTTATT CAGAGCCTTT TAGTAAAAAA TCCAGAGAAA 840

AGACCAACAG CAGAGATATG CCTTTCTCAT TCTTGGCTAC AGCAGTGGGA CTTTGAAAAC 900

TTGTTTCACC CTGAAGAAAC TTCCAGTTCC TCTCAAACTC AGGATCATTC TATAAGGTCC 960

TCTGAAGACA AGACTTCTAA ATCCTCCTGT AATGGAACCT GTGGTGATAG AGAAGACAAA 1020

GAGAATATCC CAGAGGATAG CAGCATGGTT TCCAAAAGAT TTCGTTTCGA TGACTCATTA 1080

CCCAATCCCC ATGAACTTGT TTCAGATTTG CTTTGTTAG 1119

Domain Profile

S: 3     tgkelgsGkfavvrkcrekstGkeyaakflkkrrlkssrrgvsreeierevavlkeirse  62

         t+kelg+Gkfavvr+c++kstG+eyaakflkkrr    r++++r+ei +e+avl++++s+

Q: 35    TSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRR----RGQDCRAEILHEIAVLELAKSC  90

         789*******************************....**********************

S: 63    pnvinlhevyenksdvililelvaGGelfd..llaekeslseeeatellkqilegvkylh  120

         p+vinlhevyen+s++ilile++aGGe+f+  l + +e++se+++++l+kqilegv+ylh

Q: 91    PRVINLHEVYENTSEIILILEYAAGGEIFNlcLPELAEMVSENDVIRLIKQILEGVYYLH  150

         ******************************877899************************

S: 121   skkivhldlkPenillldkkvpkgdiklidfGlsrkieegaelkeilGtPefvaPeivny  180

         +++ivhldlkP+nill++ + p gdik++dfG+srki +++el+ei+GtPe++aPei+ny

Q: 151   QNNIVHLDLKPQNILLSSIY-PLGDIKIVDFGMSRKIGHACELREIMGTPEYLAPEILNY  209

         ********************.***************************************

S: 181   eplsletdmwsiGvityillsgasPflGdtkqetllnisavnldfseelfssvselakdf  240

         +p++++tdmw+iG+i+y+ll+++sPf+G+++qet+lnis+vn+d+see+fssvs+la+df

Q: 210   DPITTATDMWNIGIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDF  269

         ************************************************************

S: 241   irrllvkdpekrltieeclehswl  264

         i++llvk+pekr t+e cl+hswl

Q: 270   IQSLLVKNPEKRPTAEICLSHSWL  293

         ***********************7

Domain Sequence
(FASTA)

TSKELGRGKF AVVRQCISKS TGQEYAAKFL KKRRRGQDCR AEILHEIAVL ELAKSCPRVI 60

NLHEVYENTS EIILILEYAA GGEIFNLCLP ELAEMVSEND VIRLIKQILE GVYYLHQNNI 120

VHLDLKPQNI LLSSIYPLGD IKIVDFGMSR KIGHACELRE IMGTPEYLAP EILNYDPITT 180

ATDMWNIGII AYMLLTHTSP FVGEDNQETY LNISQVNVDY SEETFSSVSQ LATDFIQSLL 240

VKNPEKRPTA EICLSHSWL 259

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006917	; P:induction of apoptosis

KEGG

pon:100442984

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013