EKS-POA-00204

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-POA-00204

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	336.6	9.5E-101	1	267	267

Status

Unreviewed

Ensembl Protein

ENSPPYP00000016576

UniProt Accession

H2PDM5;

Protein Name

Protein Synonyms/Alias

Cyclin-dependent kinase-like 2;

Gene Name

CDKL2

Gene Synonyms/Alias

CDKL2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSPPYG00000014845	ENSPPYP00000016576	ENSPPYT00000017251

Organism

Pongo abelii

Functional Description

Protein Length

471

Protein Sequence
(FASTA)

MVMKCRNKDT GRIVAIKKFL ESDDDKMVKK IAMREIKLLK QLRHENLVNL LEVCKKKKRW 60

YLVFEFVDHT ILDDLELFPN GLDYQVVQKY LFQIINGIGF CHSHNVNISD ICIIPLEHAK 120

SENLKFEMLW LAFPLSITSV LKKFWVLEHI RMPDFHHIAF RAVDVWAIGC LVTEMFMGEP 180

LFPGDSDIDQ LYHIMMCLGN LIPRHQELFY KNPVFAGVRL PEIKEREPLE RRYPKLSEVV 240

IDLAKKCLHI DPDKRPFCAE LLHHDFFQMD GFAERFSQLQ LKVQKDAKNV SLSKSQNRKK 300

EKEKDDSLGE ERKTLVVQDT NADPKIKDCK LFKIKGSKID GEKAEKGSRA SNASCLHDSR 360

TSHNKIVPST SLKDCSNVSV DHTRNPSVAI PPLTHNLSAV APGINSGMGT ATIPIQGYRV 420

DEKTKKCSIP FVKPNRHSPS GIYNINVTTL VSGPPLSDDS GADLPQMEHQ H 471

Nucleotide Sequence
(FASTA)

ATGGTGATGA AGTGTAGGAA TAAAGATACT GGAAGAATTG TGGCCATAAA GAAGTTCTTA 60

GAAAGTGACG ATGACAAAAT GGTTAAAAAG ATCGCAATGC GAGAAATCAA GTTACTAAAG 120

CAACTGAGGC ATGAAAACTT GGTGAATCTC TTGGAAGTGT GTAAGAAAAA AAAACGGTGG 180

TACCTAGTCT TTGAATTTGT TGACCACACA ATTCTTGATG ACTTGGAGCT CTTTCCAAAT 240

GGACTAGACT ACCAAGTAGT TCAGAAGTAT TTGTTTCAGA TTATTAATGG AATTGGATTT 300

TGTCACAGTC ACAATGTAAA CATCAGTGAT ATTTGCATTA TACCATTGGA GCATGCCAAA 360

TCTGAGAATC TGAAATTTGA AATGCTCTGG TTGGCATTTC CTTTGAGCAT CACCTCCGTG 420

CTCAAAAAGT TTTGGGTTTT GGAGCATATT AGGATGCCAG ATTTTCACCA CATTGCTTTT 480

AGGGCTGTTG ATGTGTGGGC CATTGGTTGT CTGGTAACTG AAATGTTCAT GGGGGAACCC 540

CTATTTCCTG GAGATTCTGA TATTGATCAG CTATATCATA TTATGATGTG TTTAGGTAAT 600

CTAATTCCAA GACATCAGGA GCTTTTTTAT AAAAATCCTG TGTTTGCTGG AGTAAGGTTG 660

CCTGAAATCA AGGAAAGAGA ACCTCTTGAA AGACGCTATC CTAAGCTCTC TGAAGTGGTG 720

ATAGATTTAG CAAAGAAATG CTTACATATT GACCCGGACA AAAGACCCTT CTGTGCTGAG 780

CTCCTACACC ATGATTTCTT TCAAATGGAT GGATTTGCTG AGAGGTTTTC CCAACTACAG 840

TTAAAAGTAC AGAAAGATGC CAAAAATGTT TCTTTATCTA AATCCCAAAA CAGAAAGAAG 900

GAAAAAGAAA AAGATGATTC CTTAGGTGAA GAAAGAAAAA CACTTGTGGT ACAGGATACC 960

AATGCTGATC CCAAAATTAA GGATTGTAAA CTATTTAAAA TAAAAGGCTC AAAAATTGAT 1020

GGAGAAAAAG CTGAAAAAGG CAGTAGAGCT TCAAATGCCA GCTGTCTCCA TGACAGTAGG 1080

ACAAGTCACA ACAAAATAGT GCCTTCAACA AGCCTCAAAG ACTGCAGCAA TGTCAGCGTG 1140

GACCACACAA GGAATCCAAG CGTGGCAATT CCCCCACTTA CACACAATCT TTCTGCAGTT 1200

GCTCCCGGCA TTAATTCTGG AATGGGGACT GCGACTATAC CAATTCAGGG TTACAGAGTG 1260

GATGAGAAAA CTAAGAAGTG TTCTATTCCA TTTGTTAAAC CGAACAGGCA TTCCCCATCA 1320

GGGATTTATA ACATTAATGT GACCACATTA GTATCAGGAC CTCCCCTGTC AGATGATTCA 1380

GGGGCTGATT TGCCTCAAAT GGAACACCAG CACTGA 1416

Domain Profile

S: 14    vvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenlvnllevfrrkkkl  73

         +v+kcrnkdtg+ivaikkfles+ddk+vkkia+reikllkql+henlvnllev+++kk++

Q: 1     MVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRW  60

         79**********************************************************

S: 74    ylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknniihrdikpenilisk  133

         ylvfe+vd+t+ld+le +pnG+++++v+k+l+qi+++i fch++n+   di    +  +k

Q: 61    YLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNVNISDICIIPLEHAK  120

         ****************************************************99999***

S: 134   sgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksvdvwaiGcllaell  193

         s+ +k+  + +a  l+  + v  ++      r p++        ++vdvwaiGcl++e++

Q: 121   SENLKFEMLWLAFPLS-ITSVLKKFWVLEHIRMPDFHHI--A-FRAVDVWAIGCLVTEMF  176

         *********99*9999.7788899999999****98644..3.489**************

S: 194   tGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpevedleslekkypkl  253

         +Geplfpg+sd+dqly+i+++lG+liprhq++f+kn+vfaGv+lpe++++e+le++ypkl

Q: 177   MGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFYKNPVFAGVRLPEIKEREPLERRYPKL  236

         ************************************************************

S: 254   nevlldllkkclkldpaerlsceellkheyf  284

         +ev++dl+kkcl++dp++r +c+ell+h++f

Q: 237   SEVVIDLAKKCLHIDPDKRPFCAELLHHDFF  267

         *****************************98

Domain Sequence
(FASTA)

MVMKCRNKDT GRIVAIKKFL ESDDDKMVKK IAMREIKLLK QLRHENLVNL LEVCKKKKRW 60

YLVFEFVDHT ILDDLELFPN GLDYQVVQKY LFQIINGIGF CHSHNVNISD ICIIPLEHAK 120

SENLKFEMLW LAFPLSITSV LKKFWVLEHI RMPDFHHIAF RAVDVWAIGC LVTEMFMGEP 180

LFPGDSDIDQ LYHIMMCLGN LIPRHQELFY KNPVFAGVRL PEIKEREPLE RRYPKLSEVV 240

IDLAKKCLHI DPDKRPFCAE LLHHDFF 267

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>